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| Patent # | Description |
|---|---|
| 2017/0291907 |
Thienopyrimidine Compounds Compounds of formula (I) are A.sub.2B receptor antagonists: ##STR00001## Wherein R.sub.1 is optionally substituted aryl or an optionally substituted 5- or... |
| 2017/0291906 |
COMPOUNDS FROM RENEWABLE RESOURCES Compounds of formula III: ##STR00001## and salts thereof are disclosed. Also disclosed are methods for preparing compounds of formula III, intermediates useful... |
| 2017/0291905 |
ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Described herein are compounds of Formula (S-I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein... |
| 2017/0291904 |
COMPOUNDS AND METHODS The subject matter generally relates to compounds and methods of treatment and/or prophylaxis of CNS diseases, disorders, and/or injuries. In one aspect, the... |
| 2017/0291903 |
Imidazopyrazinones as PDE1 Inhibitors The present invention provides imidazopyrazinones as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative... |
| 2017/0291902 |
sGC STIMULATORS The present patent application discloses at least the compounds according to Formula I' shown below, or pharmaceutically acceptable salts thereof, ##STR00001## ... |
| 2017/0291901 |
1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and
1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones as PDE1 Inhibitors The present invention provides 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones of formula (I) as PDE1 ... |
| 2017/0291900 |
FLUORINATED INTEGRIN ANTAGONISTS The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to... |
| 2017/0291899 |
NAPHTHYRIDINE DERIVATIVES AS ALPHA V BETA 6 INTEGRIN ANTAGONISTS FOR THE
TREATMENT OF E.G. FIBROTIC DISEASES A compound of formula (I) or a salt thereof: ##STR00001## wherein R.sub.1 represents a five-membered aromatic heterocycle selected from a N- or a C-linked mono-... |
| 2017/0291898 |
LIFE-EXTENDING AGENT, LIFE EXTENSION METHOD USING THE LIFE-EXTENDING
AGENT, NOVEL DUAL OXIDASE ACTIVATOR,... The present invention provides a life-extending agent comprising pyrroloquinoline quinone and/or a derivative of the pyrroloquinoline quinone. |
| 2017/0291897 |
THERAPEUTIC COMPOUNDS AS INHIBITORS OF THE OREXIN-1 RECEPTOR The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The... |
| 2017/0291896 |
PYRAZOLO[3,4-C]PYRIDINE DERIVATIVES Disclosed are a compound of formula (I), a tautomer, an optical isomer or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition... |
| 2017/0291895 |
GLS1 INHIBITORS FOR TREATING DISEASE Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: ... |
| 2017/0291894 |
NOVEL GPR119 AGONIST COMPOUNDS The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds. ##STR00001## |
| 2017/0291893 |
PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with... |
| 2017/0291892 |
SUBSTITUTED OXOPYRIDINE DERIVATIVES The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of... |
| 2017/0291891 |
SUBSTITUTED PYRIDINE-PIPERAZINYL ANALOGUES AS RSV ANTIVIRAL COMPOUNDS The invention concerns novel substituted pyridine-piperazinyl analogues of formula (I) having antiviral activity, in particular, having an inhibitory activity... |
| 2017/0291890 |
HETEROCYCLE SUBSTITUTED AMINO-PYRIDINE COMPOUNDS AND METHODS OF USE
THEREOF The present disclosure relates to heterocycle substituted amino-pyridine compounds. The present disclosure also relates to pharmaceutical compositions... |
| 2017/0291889 |
PYRAZOLE DERIVATIVES AS SGC STIMULATORS Compounds are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for... |
| 2017/0291888 |
1,2,4-TRIAZINE-4-AMINE DERIVATIVES According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the... |
| 2017/0291887 |
PYRIMIDINES FOR TREATMENT OF BACTERIAL INFECTIONS Filamenting temperature-sensitive mutant Z (FtsZ) protein plays a crucial role in the bacterial cell division machinery and is a validated drug target for... |
| 2017/0291886 |
METHODS FOR TREATING PROTOZOAN INFECTIONS The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of... |
| 2017/0291885 |
METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED
THEREIN Provided is a method for preparing an enamide compound, which includes reacting an organic azide compound having .alpha.-hydrogen and an anhydride by addition... |
| 2017/0291884 |
HIGH-COVERAGE, LOW ODER MALODOR COUNTERACTANT COMPOUNDS AND METHODS OF USE The present invention relates to novel compounds and their use as malodor counteractant materials. |
| 2017/0291883 |
SALT OF DICARBOXYLIC ACID COMPOUND It is an object of the present invention to provide a medicament for preventing or treating hyperphosphatemia. The solution is crystals, or hydrate thereof, of... |
| 2017/0291882 |
Solid Forms of Mirabegron Solid forms of Mirabegron, including forms APO-I, APO-II, and various salt forms, and processes for the preparation thereof, are provided. |
| 2017/0291881 |
EFFICIENT AND SCALABLE SYNTHESIS OF
2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID METHYL ESTER AND
... Methods of synthesizing 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) and structural analogs thereof. The methods include... |
| 2017/0291880 |
PROCESS FOR THE PREPARATION OF TOLTRAZURIL AND AN INTERMEDIATE USEFUL FOR
ITS PREPARATION Disclosed is a process for the preparation of toltrazuril of formula (I) via the intermediate ... |
| 2017/0291879 |
Cancer Cell Growth Inhibitor, Anticancer Agent, and Method for Screening
Same, as well as Novel Compound A cancer cell proliferation inhibitor including at least one selected from compounds represented by Structural Formulae (1) to (8), wherein the cancer cell is... |
| 2017/0291878 |
METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE A method for producing a compound (3), which comprises allowing a compound (1) to react with hydrogen gas in an inert solvent, in the presence of a specific... |
| 2017/0291877 |
ANTIMICROBIAL IMIDAZOLIUM COMPOUNDS The present invention relates to antimicrobial imidazolium compounds having the structure of Formula (I) wherein R is an optionally substituted aliphatic group... |
| 2017/0291876 |
ASYMMETRICALLY CATALYZED SYNTHESIS METHOD OF NITROPYRAZOLE AMIDE COMPOUND A synthesis method of .gamma.-nitropyrazole amide compound through asymmetrical catalyzing technique is provided, a nitroalkane and an ... |
| 2017/0291875 |
QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS The present invention provides compounds of formula (I) as described herein and pharmaceutically acceptable salts, hydrates and solvates thereof for use in... |
| 2017/0291874 |
Process for the Manufacture of Idalopirdine via Hydrogenation of an Imine The present invention relates to the preparation of N-(2-(6-fluoro-1H-indol-3-yl)-ethyl)-3-(2,2,3,3-tetrafluoropropoxy)-benzy- lamine (Compound I), INN-name... |
| 2017/0291873 |
Beta-Mercaptoethanol Synthesis A process includes reacting, in a reactor having a fixed bed containing a solid catalyst which contains a heterogeneous ion exchange resin, hydrogen sulfide... |
| 2017/0291872 |
Mixed Decyl Mercaptans Compositions and Methods of Making Same Compositions comprising branched C.sub.10 mercaptans selected from the group consisting of 5-methyl-1-mercapto-nonane, 3-propyl-1-mercapto-heptane,... |
| 2017/0291871 |
2,2' -DIAMINOBIARYLS HAVING ONE PRIMARY AND ONE SECONDARY AMINE Novel 2,2'-diaminobiaryls having one primary and one secondary amine and an electrochemical process for preparation thereof. |
| 2017/0291870 |
SURFACTANT-CONTAINING AMIDE COMPOUND SOLUTION The present invention relates to an amide compound solution comprising an amide compound and a surfactant. More specifically, the invention relates to an amide... |
| 2017/0291869 |
EXHAUST GAS CLEANING IN A METHOD FOR CONTINUOUSLY PRODUCING DINITROTOLUENE The invention relates to a method for producing dinitrotoluene, comprising the following steps: a) nitrating toluene with a mixture of nitric acid and sulfuric... |
| 2017/0291868 |
Diesters for Personal Care Applications Derived from 1-Methylheptyl
Alcohol The invention includes a diester exhibiting improved hydrolytic stability that is an esterification product of a 1-methylheptyl alcohol and a dicarboxylic... |
| 2017/0291867 |
Improved Process for Hydrogenation of Benzenepolycarboxylic Acids and
Derivatives Thereof A process for ring hydrogenation of a benzenepolycarboxylic acid or derivative thereof, includes contacting a feed stream comprising the acid or derivative... |
| 2017/0291866 |
Production of Mixed Aldol Products from the Products of Hydroformylation
Reactions A method for producing mixed aldol products from the products of hydroformylation reactions. In one embodiment, the method comprises mixing hydroformylation... |
| 2017/0291865 |
POLYFLUOROALKYL ALLYL COMPOUND AND METHOD FOR PRODUCING THE SAME A polyfluoroalkyl allyl compound represented by the general formula: CF.sub.3(CF.sub.2).sub.n(CH.sub.2CF.sub.2).sub.a(CF.sub.2CF.sub.2).sub.b- ... |
| 2017/0291864 |
Production of Isobutylene, Isoamylene, or Alkylates from Mixed Alkanes A method includes brominating a butanes feed stream including i-butane in a bromination reactor to form a bromination effluent stream including t-butyl... |
| 2017/0291863 |
METHOD FOR PRODUCING OLEFIN CONTAINING CHLORINE AND FLUORINE A method for producing at least one olefin compound selected from the group consisting of a compound of formula (51) and a compound of formula (52), the method... |
| 2017/0291862 |
METHOD FOR PRODUCING OLEFIN A method for producing at least one olefin compound selected from the group consisting of a compound of formula (51), a compound of formula (52), a compound of... |
| 2017/0291860 |
METHANE CONVERSION APPARATUS AND PROCESS USING A SUPERSONIC FLOW REACTOR Apparatus and methods are provided for converting methane in a feed stream to acetylene. A hydrocarbon stream is introduced into a supersonic reactor and... |
| 2017/0291859 |
METHOD FOR THE PRODUCTION OF BUTADIENE AND HYDROGEN FROM ETHANOL IN TWO
LOW-WATER AND LOW-ENERGY-CONSUMPTION... The invention concerns a process for the production of butadiene from an ethanol feed comprising at least 80% by weight of ethanol, comprising at least one... |
| 2017/0291858 |
LIGHTWEIGHT ASSEMBLABLE APPLIANCE WITH PLIANT EXOSKELETAL SUPPORT
RESPECTIVE KIT-OF-PARTS AND METHOD FOR... An assemblable appliance and method of recycling organic waste into biogas and liquid fertilizer, implementing essentially anaerobic digestion processes, is... |
| 2017/0291857 |
Fermented Soil Additive A soil additive comprising a sugar ferment wherein said ferment contains signalling molecules comprising between about 1-50% of the organic matter present in... |
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