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Patent # Description
2017/0335413 Cell Surface Marker Depletion in a Sample Processing Device
The disclosure provides methods, devices, and kits for conducting a quantitative analysis of a whole blood sample. Various modifications to the disclosed...
2017/0335412 System and Methods For The Detection of Multiple Chemical Compounds
Methods that may be used for the electrochemical detection of multiple parameters, including chemical compounds. Further provided are cells that may be used in...
2017/0335411 CORRECTING CROSSTALK IN BIOLOGICAL SYSTEMS
Aspects of the present disclosure are directed to biosensing circuits that correct crosstalk.
2017/0335410 High Throughput Method for Identification and Sequencing of Unknown Microbial and Eukaryotic Genomes from...
Disclosed are methods for screening biological samples for the presence unknown microbes, such as bacteria and archaea or unknown eukaryotes using rRNA gene...
2017/0335409 DETECTION OF HUMAN UMBILICAL CORD TISSUE-DERIVED CELLS
The invention relates to methods for detecting allogeneic therapeutic cells (such as human umbilical cord tissue-derived cells (hUTC)) in blood. The methods...
2017/0335408 Methods and Systems of Multi-Assay Processing and Analysis
The instant disclosure provides methods of multi-assay processing and multi-assay analysis. Such multi-assay processing and analysis pertain to automated...
2017/0335407 METHOD FOR DETECTING METHYLATION OF COLORECTAL CANCER SPECIFIC METHYLATION MARKER GENE FOR COLORECTAL CANCER...
The present disclosure relates to a method for detecting methylation of the bowel-cancer-specific methylation marker GPM6A (NM_201591, glycoprotein M6A) gene...
2017/0335406 METASTASIS SPECIFIC SPLICE VARIANTS OF MENA AND USES THEREOF IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF TUMORS
Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression...
2017/0335405 METHOD FOR DETECTING THE METHYLATION OF COLORECTAL-CANCER-SPECIFIC METHYLATION MARKER GENES FOR COLORECTAL...
The present disclosure relates to a method for detecting CpG methylation of SDC2 (Syndecan 2) gene, a kit for detecting CpG methylation of SDC2 (Syndecan 2)...
2017/0335404 INHIBITORS OF CELL ADHESION
Nectin-4 and Nectin-1 in cancer progression/development and as a therapeutic target for cancer.
2017/0335403 METHODS FOR DIAGNOSIS AND PROGNOSIS OF EPITHELIAL TUMORS
A biomarker is disclosed that can distinguish aggressive epithelial tumors in a tissue biopsy from, for example, normal, hyperplastic, and benign neoplastic...
2017/0335402 DOT1L INHIBITORS AND USES THEREOF
The present disclosure relates to methods of treating AML, associated with DNMT3A mutations by administering one or more DOT1L inhibitors or related...
2017/0335401 DETECTION OF LUNG NEOPLASIA BY ANALYSIS OF METHYLATED DNA
Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the...
2017/0335400 COMPOSITIONS AND METHODS FOR TREATING CANCERS
The present invention relates to compositions and methods for treating of cancer. In some embodiments, the invention relates to the use of agents that can...
2017/0335399 DETECTION OF MINERALOCORTICOID RECEPTOR ACTIVATION AND PERSONALIZED ANTIHYPERTENSIVE THERAPY BASED THEREON
Provided herein are compositions and methods for the assessment of mineralocorticoid receptor activation or repression, and methods of customizing...
2017/0335398 METHOD TO PREDICT LIKELIHOOD OF INHERITED PERIPHERAL NEUROPATHY IN MAMMALS
Methods and kits for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a...
2017/0335397 METHOD AND DEVICE FOR DIAGNOSING ORGAN INJURY
The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine and isolating corresponding mRNA in order to diagnose and...
2017/0335396 SYSTEMS AND METHODS OF DIAGNOSING IDIOPATHIC PULMONARY FIBROSIS ON TRANSBRONCHIAL BIOPSIES USING MACHINE...
The present invention provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UIP) or non-UIP.
2017/0335395 A PARKINSON'S DISEASE DIAGNOSTIC BIOMARKER PANEL
The present invention relates to a method of diagnosing Parkinson's disease in a subject using a novel set of biomarkers. The invention further includes...
2017/0335394 POLYMORPHISM IN THE APO(A) GENE PREDICT RESPONSIVENESS TO ACETYLSALICYLIC ACID TREATMENT
This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human...
2017/0335393 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS
The present invention relates to in vitro methods for the diagnosis of chronic obstructive pulmonary disease (COPD), wherein the expression of the marker gene...
2017/0335392 Methods For Telomere Length And Genomic DNA Quality Control Analysis In Pluripotent Stem Cells
The generation of clinical-grade cell-based therapies from human embryonic stein cells or cells reprogrammed to pluripotency from somatic cells, requires...
2017/0335391 HIGHLY-MULTIPLEXED SIMULTANEOUS DETECTION OF NUCLEIC ACIDS ENCODING PAIRED ADAPTIVE IMMUNE RECEPTOR...
The invention is directed to methods for highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune heterodimers from a large...
2017/0335390 METHOD FOR GENOTYPING CLONOTYPE PROFILES USING SEQUENCE TAGS
The invention is directed to sequence-based profiling of populations of nucleic acids by multiplex amplification and attachment of one or more sequence tags to...
2017/0335389 SENSOR ARRAYS AND NUCLEIC ACID SEQUENCING APPLICATIONS
Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction regions containing electronic sensors to monitor...
2017/0335387 SYSTEMS AND METHODS FOR IDENTIFYING SEQUENCE VARIATION
Systems and method for determining variants can receive mapped reads, align flow space information to a flow space representation of a corresponding portion of...
2017/0335386 METHOD OF MEASURING ADAPTIVE IMMUNITY
Compositions and methods for measuring adaptive immune receptor (T cell receptor and immunoglobulin) diversity are described, and find uses for assessing...
2017/0335385 METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES
The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a...
2017/0335384 ENZYME-PORE CONSTRUCTS
The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached...
2017/0335383 LINEAR-EXPO-LINEAR PCR (LEL-PCR)
Disclosed herein is a nucleic acid amplification process referred to as Linear-Expo-Linear Polymerase Chain Reaction (LEL-PCR).
2017/0335382 Isothermal Amplification Assay for the Detection of Short Nucleic Acid Sequences
Provided herein is a method of detecting short nucleic acids, such as microRNAs, in a sample, such as urine, and a kit for use in detection of the short...
2017/0335381 METHOD FOR DETECTING AND QUANTIFYING BIOMATERIALS BY USING ACTIVITY OF NUCLEIC ACID POLYMERASE REGULATED BY...
The present invention relates to a method of detecting and quantifying biomolecules using nucleic acid polymerase activity controlled by the target molecule,...
2017/0335380 KINETIC EXCLUSION AMPLIFICATION OF NUCLEIC ACID LIBRARIES
A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting...
2017/0335379 DETECTION OF NUCLEIC ACIDS IN CRUDE MATRICES
A method includes contacting a crude matrix with components of an isothermal nucleic acid amplification reaction for a target nucleic acid species, thereby...
2017/0335378 REAGENTS AND METHODS FOR ISOTHERMAL CHAIN REACTION
In certain aspects, the invention disclosed herein relates to the isothermal amplification of probe linkage products to generate specific amplified signals. In...
2017/0335377 SE33 MUTATIONS IMPACTING GENOTYPE CONCORDANCE
Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex...
2017/0335376 NUCLEIC ACID-INDUCED AGGREGATION OF METAL NANOPARTICLES AND USES THEREOF IN METHODS FOR DETECTING NUCLEIC ACIDS
The invention relates to an aggregate comprising metallic nanoparticles and nucleic acid molecules wherein each metallic nanoparticle is coated with a...
2017/0335375 KIT AND METHOD FOR DETECTION OF MICRORNA
The present invention relates to a kit for detecting miRNA and a method for detecting miRNA using the kit. According to the miRNA detection kit and method of...
2017/0335374 METHODS AND COMPOSITIONS FOR IDENTIFICATION OF SOURCE OF MICROBIAL CONTAMINATION IN A SAMPLE
Herein are described 1058 different bacterial taxa that were unique to either human, grazing mammal, or bird fecal wastes. These identified taxa can serve as...
2017/0335373 AUTOMATED METHOD FOR ANALYZING SAMPLES
An automated method for analyzing a plurality of samples within a housing of a self-contained system. The system is loaded with a plurality of samples, after...
2017/0335372 SPECIMEN DISRUPTING METHOD AND SPECIMEN DISRUPTING APPARATUS
A specimen disrupting apparatus includes: a drive unit that rotates the lower portion of a container having a solution that includes a specimen, a great number...
2017/0335371 Method for Fragmenting a Nucleic Acid for Sequencing
Providing herein, among other things, is a method for preparing a nucleic acid for sequencing. In some embodiments, the method comprises a) amplifying a...
2017/0335370 PRETREATMENT METHOD AND NUCLEIC-ACID-EXTRACTING KIT USABLE FOR THE SAME
The present invention provides a method capable of realizing pretreatment process of genetic screening according to a POCT mode. The method includes: making a...
2017/0335369 TAGGING NUCLEIC ACIDS FOR SEQUENCE ASSEMBLY
Various approaches for generating long-distance contiguity information to facilitate contig assembly and phase determination are disclosed. Nucleic acids are...
2017/0335368 LUCIFERIN-CONTAINING SUBSTRATE AND MONITORING DEVICE INCLUDING THE SUBSTRATE
Luciferin-containing substrates are provided including a substrate and luciferin dried on the substrate. The luciferin-containing substrate is free of a...
2017/0335367 METHOD TO PREDICT THE LACK OF RESPONSE TO ANTI-TNF ALPHA THERAPIES
This invention provides methods for predicting response to anti-TNF.alpha. biological agent treatment in a rheumatoid arthritis patient and methods for...
2017/0335366 Method for the Colorimetric Detection of Contamination with Nucleases
Method for detecting the presence of nucleases in a sample, characterized in that it comprises the steps of: --incubating the sample to be tested for the...
2017/0335365 METHOD FOR DETECTING BACTERIA
The present invention provides a novel method for more simply and rapidly detecting target bacterial cells by a device using a binding molecule capable of...
2017/0335364 METHOD FOR DETECTING ORGANISMS IN A DILUTED SAMPLE
The invention relates to a method for detecting organisms in a liquid sample, comprising the provision of a capture area including particles in a liquid medium...
2017/0335363 Enzyme Electrode and Biosensor Using the Same
The disclosure discloses an enzyme electrode comprising; an electrode comprising a current collector; a monolayer-forming molecule bound to the surface of the...
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