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Patent # Description
2018/0000935 Stable Antibody Containing Compositions
The invention relates to stable and low viscous (<50 cP) protein containing compositions, in particular, but not exclusively stable antibody containing...
2018/0000932 FORMULATION OF AGLYCOSYLATED THERAPEUTIC ANTIBODIES
Described herein are antibody formulations including a therapeutic antibody at a concentration of at least 20 mg/ml, methods for optimizing and producing such...
2018/0000929 D-AMINO ACID DERIVATIVE-MODIFIED PEPTIDOGLYCAN AND METHODS OF USE THEREOF
The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria...
2018/0000926 METHODS OF INDUCING AN IMMUNE RESPONSE TO HEPATITIS C VIRUS
The present disclosure provides methods for inducing an immune response to hepatitis C virus (HCV) in an individual. The present disclosure provides methods...
2018/0000925 VIRAL RNA SEGMENTS AS IMMUNOMODULATORY AGENTS AND VACCINE COMPONENTS
The disclosure provides compositions and methods involving viral RNA segments for use in modulating immune responses, including inhibition inflammation related...
2018/0000923 NEISSERIA MENINGITIDIS COMPOSITIONS AND METHODS THEREOF
In one aspect, the invention relates to a composition including a first polypeptide having the sequence set forth in SEQ ID NO: 1 and a second polypeptide...
2018/0000922 Immunogenic Compositions for Use in Pneumococcal Vaccines
An object of the present invention is to provide immunogenic compositions for protection against S. pneumoniae, in particular against S. pneumoniae serogroup...
2018/0000918 VACCINE COMPOSITIONS FOR USE AGAINST ENTEROTOXIGENIC ESCHERICHIA COLI
The present disclosure provides vaccine compositions for use against enterotoxigenic Escherichia coli (ETEC) comprising EtpA and EatA. EtpA and EatA are...
2018/0000916 ANTIGEN PRESENTING CELL TARGETED CANCER VACCINES
The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen...
2018/0000914 ANTI-HSP70 SPECIFIC CHIMERIC ANTIGEN RECEPTORS (CARS) FOR CANCER IMMUNOTHERAPY
The present invention relates to Chimeric Antigen Receptors (CAR) that are recombinant chimeric proteins able to redirect immune cell specificity and...
2018/0000912 Virus Vectors Expressing Multiple Epitopes of Tumor Associated Antigens For Inducing Antitumor Immunity
Provided are polynucleotides and viral vectors, particularly, alphavirus vectors such as Sindbis viral vectors, which encode multiple, e.g., two or more,...
2018/0000909 TREATMENT OF PSYCHOLOGICAL TRAUMA
The present specification discloses methods of treating a psychological trauma in an individual using botulinum toxins and/or a Targeted Exocytosis Modulator,...
2018/0000908 Methods of Treatment
The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin...
2018/0000906 MULTILAMELLAR LIPID VESICLE COMPOSITIONS INCLUDING A CONJUGATED ANAPLASTIC LYMPHOMA KINASE (ALK) VARIANT AND...
The invention provides compositions including stabilized multilamellar lipid vesicles having crosslinked lipid bilayers (referred to herein as ...
2018/0000905 COMPOSITION AND METHODS FOR TREATING ISCHEMIC WOUNDS AND INFLAMMATORY CONDITIONS
Methods, compositions, and treatment protocols for treating ischemic wounds and inflammatory conditions in a patient. The treatment protocols comprise or...
2018/0000902 PREVENTION OF HYPOGLYCAEMIA IN DIABETES MELLITUS TYPE 2 PATIENTS
A method for the prevention of hypoglycaemia in diabetes mellitus type 2 comprising administering (a) desPro.sup.36Exendin-4(1-39)-Lys.sub.6-NH.sub.2 or/and a...
2018/0000898 Method of Treating or Ameliorating Type 1 Diabetes Using FGF21
Methods of treating metabolic diseases and disorders using a FGF21 polypeptide are provided. In various embodiments the metabolic disease or disorder is type 1...
2018/0000897 Method of treating pain using agents that promote neuronal differentiation
The present invention is based on the seminal concept of treating pain by promoting neuronal differentiation. The invention provides a method of treating pain...
2018/0000896 NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING GASTROINTESTINAL AND GASTRIC CANCER
A method of treating a patient who has gastric cancer, gastrointestinal cancer, colorectal cancer, pancreatic cancer, lung cancer, and/or renal cancer includes...
2018/0000895 METHOD FOR THE TREATMENT OF MALIGNANCIES
The present invention provides for the intratumoral delivery of immunomodulators. In particular, it provides delivery of co-stimulatory molecules using...
2018/0000893 COMPOSITIONS AND METHODS FOR DELIVERING LYPOPHILIC AGENTS TO DENTAL PULP AND FOR ENHANCING DENTIN PRODUCTION
Methods and compositions are provided for enhancing dentin production, and for delivering a lipophilic agent to pulp tissue of a tooth of an individual. In...
2018/0000891 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0000890 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0000888 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0000887 Treatment of Ascites
A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites...
2018/0000884 PROCESS FOR MANUFACTURING GLATIRAMER ACETATE PRODUCT
The patent provides a process of preparing a pharmaceutical preparation of glatiramer acetate and mannitol in a suitable container comprising the steps of: ...
2018/0000883 METHOD OF TREATING ISCHEMIC HEART DISEASE
A method of treating ischemic heart disease can include administering a therapeutically effective amount of a composition including date seed nanoparticles to...
2018/0000881 Phosphatidylserine-Containing Diet Supplement Aids With Melatonin Anti-Catabolic Dietary Nutrients
A supplement includes plant-derived phosphatidylserine in a physiologically beneficial amount and at least one plant-based concentrate or extract which...
2018/0000880 METHODS OF TREATING OR PREVENTING OVERWEIGHT AND OBSESITY IN MAMMALS BY ADMINISTERING A COMPOSITION COMPRISING...
The present invention is based on the discovery that mannoheptulose (mHep) reduces or inhibits the differentiation process of fat stem cells into adipocytes so...
2018/0000879 Methods of Purifying Cannabinoids, Compositions and Kits Thereof
The present specification discloses methods of purifying one or more cannabinoids from a plant material, purified cannabinoids and pharmaceutical compositions...
2018/0000878 PREBIOTIC FORMULATIONS
Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods...
2018/0000876 COMPOSITIONS AND METHODS FOR PROMOTING GROWTH OF BENEFICIAL MICROBES TO TREAT OR PREVENT DISEASE OR PROLONG LIFE
Inoculation of ATM-deficient mice with probiotic microorganisms, such as L. johnsonii, changed immune parameters, decreased a marker of DNA damage and...
2018/0000875 PROBIOTICS FOR USE IN REDUCING THE INCIDENCE AND DURATION OF ILLNESS
The present invention provides probiotic compositions suitable for reducing the incidence and duration of human illness. In particular, the present invention...
2018/0000874 Human disease mitigation with food formulation
A method of administering a food containing at least transfer factor and lactic acid generating bacteria to mitigate the symptoms of a specific human disease...
2018/0000873 Bacillus coagulans MTCC 5856 For The Management of Major Depressive Disorder
The present invention discloses the use of probiotics for therapeutic management of major depressive disorder (MDD). Specifically, the invention discloses the...
2018/0000871 COMPOSITION
The present invention provides a composition comprising: honey; bee pollen; royal jelly; and propolis, wherein the content of the honey is 70% by mass or more...
2018/0000867 Disease Prevention and Alleviation by Human Myoblast Transplantation
Methods and materials are described for human genome prophylaxis and therapy of diseases using myoblast transfer. These methods result in gene transcript...
2018/0000866 ISOLATION, CULTIVATION AND USES OF STEM/PROGENITOR CELLS
The present invention relates to a method of cultivating an epithelial stem/progenitor cell population of the amniotic membrane of umbilical cord, the...
2018/0000865 MACROPHAGES EAT CANCER CELLS USING THEIR OWN CALRETICULIN AS A GUIDE
Therapeutic and diagnostic methods are provided, which methods relate to the induction of expression of calreticulin on phagocytic cells. Specifically, the...
2018/0000863 PEROXIDE FORMULATIONS AND METHODS AND APPLICATORS FOR USING THE SAME
Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and...
2018/0000862 METHODS OF TREATING A TREATMENT-RESISTANT GASTROINTESTINAL SPASM
Methods of treating a gastrointestinal spasm in a subject are provided. The methods can include administering an effective amount of a formulation to treat the...
2018/0000861 Gold Particle for Use in Therapy to Prevent Scar Formation
A gold particle having at least one cross-section in the range of 20-1000 .mu.nm and having a purity greater than 99.00% w/w, preferably 99.99% w/w for use in...
2018/0000857 DECARBOXYLATED CANNABIS RESINS, USES THEREOF AND METHODS OF MAKING SAME
The disclosure relates to decarboxylated cannabis resins and methods of making the decarboxylated cannabis resins by extraction and decarboxylation of...
2018/0000856 ANTIOXIDANT AGENT, AND ANTIOXIDANT COSMETIC AND UV CARE COSMETIC
The present invention provides an antioxidant, an ROS inhibitor, an antioxidant enzyme production promoter, an antioxidant cosmetic, a UV care cosmetic, a...
2018/0000855 NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS
Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its...
2018/0000854 STABLE FORMULATIONS FOR THE ORAL ADMINISTRATION OF AMPHOTERICIN B AND RELATED METHODS
The present invention provides oral AmpB and/or protease inhibitor formulations and their use to treat infectious disease, including HIV.
2018/0000852 Method of Treating Neurological Conditions with Oleandrin
A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or...
2018/0000851 COMBINATION TUMOR IMMUNOTHERAPY
Provided are methods for treating cancer using local administration of certain CpG oligonucleotides (CpG ODN) and systemic administration of a checkpoint...
2018/0000848 Osteoclast Inhibitors for Knee Conditions
Oral dosage forms of osteoclast inhibitors, such as neridronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2018/0000844 STABLE FIXED DOSE PHARMACEUTICAL COMPOSITION COMPRISING MOMETASONE AND OLOPATADINE
The present invention relates to a stable fixed dose aqueous pharmaceutical composition (e.g., contained in a container) for nasal administration to a human,...
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