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Patent # Description
2018/0042932 COMBINATION OF BRIMONIDINE AND TIMOLOL FOR TOPICAL OPHTHALMIC USE
Disclosed are pharmaceutical compositions comprising brimonidine and timolol for topical ophthalmic delivery and a method of treatment comprising administering...
2018/0042931 N-PHENYL-(MORPHOLIN-4-YL OR PIPERAZINYL)ACETAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE WNT SIGNALLING...
The present invention relates to inhibitors of the Wnt signalling pathways of general formula (I) wherein L.sup.A represents *CH.sub.2** or *.DELTA.**; wherein...
2018/0042930 METHODS OF TREATMENT OF MALIGNANCIES
Provided are methods and compositions for treating a malignancy in patients carrying an IDH2 mutation.
2018/0042929 USE OF SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES
The present invention relates to: use of a 2,3-dihydroimidazo[1,2-c]quinazoline compound, or of a pharmaceutical composition containing same, as a sole active...
2018/0042928 METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION
The present disclosure relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present...
2018/0042927 PHOSPHODIESTERASE INHIBITORS TO REPAIR BRAIN AND/OR RETINAL INJURY IN HUMAN NEWBORNS
The present disclosure concerns the use of a phosphodiesterase inhibitor, such as, for example, sildenafil, to repair a brain and/or a retinal injury in a...
2018/0042926 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS
Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in...
2018/0042925 METHODS FOR TREATING CANCER
Some embodiments of the invention include methods to treat cancer in animals by administering an SCD inhibitor. Other embodiments include treating cancer in...
2018/0042924 PHARMACEUTICAL FORMULATIONS, PROCESSES, SOLID FORMS AND METHODS OF USE RELATING TO ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
2018/0042923 COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS...
The present invention provides a medicament having a wider treatment spectrum, causing a fewer side effects and superior in tolerability and safety, as...
2018/0042922 COMPOSITIONS AND METHODS OF TREATING A NEURODEGENERATIVE DISEASE
The present application relates to novel compositions useful for the treatment of a neurodegenerative disease and uses thereof. The present application also...
2018/0042921 METHOD OF TREATING A BRAIN TUMOR
Disclosed herein are methods of treating a brain tumor by administering Plinabulin. Some embodiments relate to treatment of glioblastoma multiforme by...
2018/0042920 NEW ABUSE-RESISTANT PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF OPIOID DEPENDENCE
There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of...
2018/0042919 PARP Inhibitors for the Treatment of Major Depressive Disorder and Related Conditions
Pharmaceutical formulations comprising an inhibitor of poly(ADP)-ribose) polymerase-1 (PARP1) and their use for the treatment of major depressive disorder and...
2018/0042918 RESPIRATORY INFECTION TREATING AGENT
[Problem] The present invention pertains to a safer and more effective respiratory infection treating agent. [Solution] A respiratory infection treating agent...
2018/0042917 COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING METABOLIC DISEASES, CONTAINING AMODIAQUINE AS ACTIVE INGREDIENT
The present invention relates to a novel use of a composition containing, as an active ingredient, an amodiaquine compound or a pharmaceutically acceptable...
2018/0042916 TREATMENT OF MULTIPLE SCLEROSIS WITH LAQUINIMOD
The subject invention provides for methods of reducing the relapse rate and/or reducing the accumulation of physical disability in a relapsing-remitting...
2018/0042915 Treatment of Retinopathy of Prematurity (ROP)
Disclosed herein are methods of treating retinopathy of prematurity (ROP) in a premature and/or low birth weight infant in need thereof, comprising ...
2018/0042914 BROMODOMAIN INHIBITOR
Described herein is the bromodomain inhibitor 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-o- ne, including crystalline forms,...
2018/0042913 USE OF LAQUINIMOD TO DELAY HUNTINGTON'S DISEASE PROGRESSION
The subject invention provides methods of treating or delaying disease progression in a subject afflicted with Huntington's disease (HD) comprising...
2018/0042912 MEDICAL PRODUCT AND METHOD FOR ELIMINATING SYMPTOMS OF NICOTINE WITHDRAWAL
In essence, the present invention relates to a medical product including between about 94% and about 98% of a saline solution, preferably a normal saline...
2018/0042911 OPHTHALMIC COMPOSITION
Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of an ophthalmic agent for treatment...
2018/0042910 THERAPEUTIC AGENT FOR FRONTAL LOBE DYSFUNCTION
The present invention provides a therapeutic and/or prophylactic agent for, for example, frontal lobe dysfunction (for example, cognitive impairment (for...
2018/0042909 Methods of Treating Cancers, Autoimmune Disorders, and Other Conditions Associated with Chronic Inflammation
In one aspect, a method of treating a disorder associated with chronic inflammation includes administering to an individual in need thereof a therapeutically...
2018/0042908 PHENYL DERIVATIVE
The compound of the formula (I-1): ##STR00001## wherein all the symbols have the same meanings as described in the specification, has two cyclic groups,...
2018/0042907 SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION
The present invention relates to an ophthalmic depot preparation comprising benzyl benzoate and/or benzyl alcohol and polyethylene glycol and/or...
2018/0042906 PHARMACEUTICAL COMPOSITIONS
The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the...
2018/0042905 METHODS OF TREATING HEPATITIS B VIRUS
The present invention relates to novel methods of treating Hepatitis B Virus by administering a KDM5 inhibitor.
2018/0042904 COMPOSITIONS AND METHODS FOR TREATING COPD AND OTHER INFLAMMATORY CONDITIONS
The present invention features, inter alia, pharmaceutical compositions and their use in the preparation of a medicament (e.g., a medicament for inflammation,...
2018/0042903 METHODS AND COMPOSITIONS FOR TREATMENT OF EPILEPTIC DISORDERS
Use of allosteric modulators and/or gaboxadol for the treatment of epileptic disorders in a subject in need thereof.
2018/0042902 Heterocyclic Compounds and Uses Thereof
Heterocyclic entities that modulate PI3 kinase activity, pharmaceutical compositions containing the heterocyclic entities, and methods of using these chemical...
2018/0042901 DRUG COMPOSITIONS COMPRISING AN ANTI-PARASITIC AND PROTON PUMP INHIBITOR
Described herein are pharmaceutical compositions including a proton pump inhibitor and an antiparasitic drug. In some embodiments, the compositions can be...
2018/0042900 Compositions and Methods employing Wolbachia FtsZ as a target for Albendazole sulfone
Compositions and Methods are described in which Albendazole sulfone binds to Wolbachia FtsZ providing anti filarial activity.
2018/0042899 Method of Treating Transplant Rejection and Autoimmune Diseases
A method of treating autoimmune diseases and transplant rejection, comprising the step of treating the autoimmune or transplant patient with an effective...
2018/0042898 V1B RECEPTOR ANTAGONIST FOR USE IN THE TREATMENT OF PATIENTS HAVING AN ELEVATED AVP LEVEL AND/OR AN ELEVATED...
The present invention relates to a vasopressin receptor 1B (V.sub.1B) antagonist for use in the treatment of depressive symptoms and/or anxiety symptoms in...
2018/0042897 IPA AS A PROTECTIVE AGENT
Provided is a method for reducing a potential for neurological damage of an animal at risk of head injury, by administering to the animal before exposure to...
2018/0042896 USE OF AMISULPRIDE AS AN ANTI-EMETIC
Amisulpride is used in the therapy of nausea, vomiting or retches. The therapy may utilize a novel injectable formulation, in unit dosage form, comprising less...
2018/0042895 TREATMENT OF AUTOIMMUNE DISEASE IN A PATIENT RECEIVING ADDITIONALLY A BETA-BLOCKER
The present invention relates to methods of treating autoimmune diseases with siponimod in patients receiving additionally a beta-blocker.
2018/0042894 EYE HEALTH COMPOSITION
Ophthalmic nutraceutical composition comprising: vitamins; trace elements; carotenoids; omega-3 fatty acids; and resveratrol.
2018/0042893 PHARMACEUTICAL COMPOSITION CONTAINING SILYBIN
A pharmaceutical composition for treating non-alcoholic fatty liver diseases consists of a silybin-phospholipid complex preparation and Pu'er tea/tea product...
2018/0042892 PHARMACEUTICAL COMPOSITION CONTAINING SILIBININ
Disclosed is a pharmaceutical composition containing silibinin, which is prepared from the following bulk drugs by weight ratio: 8.75-60 parts of silibinin,...
2018/0042891 Cancer Cell Apoptosis
There is described a therapeutic agent capable of directly or indirectly having an effect on the proteins N-methyl-D-aspartate (NMDA), Cyclooxygenase-2...
2018/0042890 CANNABIS-BASED EXTRACTS AND TOPICAL FORMULATIONS FOR USE IN SKIN DISORDERS
The present invention discloses a pharmaceutical topical composition comprising cannabidiol (CBD) or a derivative thereof and Tetrahydrocannabinol (THC) or a...
2018/0042889 METHOD FOR TREATING TAU-ASSOCIATED DISEASES USING TETRAHYDROPYRANOL DERIVATIVES
A method for treating tau-associated disease by administering a pharmaceutical composition comprising a tetrahydropyranol derivative to a subject in need is...
2018/0042888 MONENSIN WATER DISPERSIBLE GRANULES BY WET GRANULATION
The present disclosure provides a water dispersible granule formulation comprising from about 5% to about 80% (w/w) of monensin; from about 1% to about 20%...
2018/0042887 COMBINATION TREATMENT PROTOCOL
The present disclosure provides a combination and a method for treating chronic lymphocytic leukemia (CLL).
2018/0042886 METHODS OF TREATING AGE RELATED DISORDERS
The invention generally relates to methods of treating a patient having, and/or at risk of, oxidative distress disorders and/or age-related disorders. The...
2018/0042885 METHOD FOR TREATING AUTISM AND OTHER NEURODEVELOPMENTAL DISORDERS
A method for treating autism and other neurodevelopmental disorders including the step of administering an effective amount of an isothiocyanate functional...
2018/0042884 COMPOSITIONS FOR USE IN TREATING GLIOBLASTOMA
The present disclosure provides methods of treating glioblastoma multiform (GBM) in a subject in need thereof. Compositions for use in these methods are also...
2018/0042883 COMPOSITIONS AND METHODS FOR LOWERING LEVELS OF HIGH-SENSITIVITY C-REACTIVE PROTEIN (HS-CRP) IN A SUBJECT
The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy...
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