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Patent # Description
2018/0044704 Methods For Enhancing The Degradation Or Conversion Of Cellulosic Material
The present invention relates to methods for degrading or converting a cellulosic material and for producing substances from the cellulosic material under high...
2018/0044703 Method for Producing an Acidic Substance Having a Carboxyl Group
An acidic substance having a carboxyl group is produced by culturing in a medium a microorganism which has been modified to enhance expression of the ybjL...
2018/0044702 METHOD AND APPARATUS FOR PRODUCING ORGANIC SUBSTANCES
It is an object of the present invention to convert CO.sub.2 to CO by bringing about a reverse shift reaction in a relatively low-temperature condition, and...
2018/0044701 BACILLUS MUCILAGINOSUS AND HIGH-DENSITY FERMENTATION METHOD AND USE THEREOF
This invention discloses a mutated strain of wild type Bacillus mucilaginosus HSCUP-76-8 and a high-density fermentation method thereof. The mutated strain...
2018/0044700 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION
The present disclosure provides compositions and methods of site-specific modification of a target DNA, or a protein associated with a target DNA, in a...
2018/0044699 NUCLEIC ACID-CONTAINING LIPID PARTICLES AND RELATED METHODS
Lipid particles containing a nucleic acid, devices and methods for making the lipid particles, and methods for using the lipid particles.
2018/0044698 SITE-SPECIFIC INTEGRATING RECOMBINANT AAV VECTORS FOR GENE THERAPY AND IMPROVED PRODUCTION METHODS
Provided herein are methods of site-specific integration of a heterologous sequence into a host genome (e.g., by administering a recombinant adeno-associated...
2018/0044697 Methods and Compositions for Goss' Wilt Resistance in Corn
The present invention relates to the field of plant breeding. More specifically, the present invention includes a method of using haploid plants for genetic...
2018/0044696 PHACOSPORACEA RESISTANT SOYBEAN PLANTS
The present invention relates to a method of increasing resistance against fungal pathogens of the family Phacosporaceae in transgenic plants and/or plant...
2018/0044695 Method of Increasing Resistance Against Soybean Rust in Transgenic Plants by ADR-1-Gene
The present invention relates to a method of increasing resistance against soybean rust in transgenic plants and/or plant cells. In these plants, the content...
2018/0044694 DOWN-REGULATION OF A HOMEODOMAIN-LEUCINE ZIPPER I-CLASS HOMEOBOX GENE FOR IMPROVED PLANT PERFORMANCE
Methods for modulating plants using optimized ZmME293 down-regulation constructs are disclosed. Also disclosed are nucleotide sequences, constructs, vectors,...
2018/0044693 LIMITED TRANSPIRATION TRAITS AND BREEDING METHODS IN MAIZE
Methods to improve drought tolerance and increasing yield by the application limited transpiration trait in maize plants are provided. Expression of the...
2018/0044692 COLLAGEN PRODUCING PLANTS AND METHODS OF GENERATING AND USING SAME
A method of producing collagen in a plant and plants producing collagen are provided. The method is effected by expressing in the plant at least one type of a...
2018/0044691 PLANT REGULATORY SEQUENCE
The present invention relates to regulatory sequences. In particular, the invention relates to a regulatory nucleic acid molecule, at least part of which has a...
2018/0044690 METHODS AND COMPOSITIONS FOR GENE EXPRESSION IN PLANTS
The invention provides recombinant DNA molecules useful for providing efficient expression of proteins in transgenic plants, as well as compositions and...
2018/0044689 BIOLOGICAL METHODS FOR PREPARING A FATTY DICARBOXYLIC ACID
The technology relates in part to biological methods for producing a fatty dicarboxylic acid and engineered microorganisms capable of such production.
2018/0044688 CORYNEFORM BACTERIUM TRANSFORMANT AND PROCESS FOR PRODUCING ORGANIC COMPOUND USING THE SAME
A coryneform bacterium transformant engineered by the following (A) to (D): (A) enhancement of 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase...
2018/0044687 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION
The invention relates to an artificial nucleic acid molecule comprising an open reading frame and a 3'-UTR comprising at least one poly(A) sequence or a...
2018/0044686 TOOLS AND METHODS FOR USING CELL DIVISION LOCI TO CONTROL PROLIFERATION OF CELLS
The present disclosure provides molecular tools, methods and kits for using cell division loci (CDLs) to control cell proliferation in animal cells. CDLs, as...
2018/0044684 COMPOSITIONS AND METHODS FOR 3-HYDROXYPROPIONIC ACID PRODUCTION
The present application discloses genetically modified yeast cells comprising an active 3-HP fermentation pathway, and the use of these cells to produce 3-HP.
2018/0044683 METHOD FOR PRODUCING COENZYME AND TRANSFORMANT SET FOR COENZYME PRODUCTION
The present invention provides a method for synthesizing NAD.sup.+ or NADH in an enzyme reaction system requiring NAD.sup.+ or NADH so as to supplement...
2018/0044682 TREATMENT OF HYPERHIDROSIS
The present invention relates to a composition for reducing sweating in humans, characterized in that said composition comprises a compound capable of...
2018/0044681 METHODS OF TREATING CANCER HARBORING HEMIZYGOUS LOSS OF TP53
Provided herein are methods of treating a patient having a cancer that exhibits (i) a hemizygous loss of the TP53 gene; (ii) a hemizygous loss of the POLR2A...
2018/0044680 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASYMMETRIC DOUBLE-STRANDED RNA
This invention relates to compounds, compositions, and methods useful for reducing KRAS target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA)...
2018/0044679 COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION
The present invention relates to a composition for preventing or treating diseases associated with human papillomavirus (HPV), and more specifically, cancer...
2018/0044678 DOUBLE-STRANDED RIBONUCLEIC ACID FOR ADJUVANTS
The invention provides a double-stranded ribonucleic acid (dsRNA) having a chain length suitable for simultaneously showing low toxicity and high function in...
2018/0044677 Regulation of Translation of Expressed Genes
The present invention describes mRNA usage improving and/or translation-enhancing nucleic acid sequences, nucleic acid constructs comprising such sequences,...
2018/0044676 COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION
Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
2018/0044675 ANTISENSE NUCLEIC ACIDS
Provided is a drug that allows highly-efficient skipping of exon. The present invention provides an antisense oligomer wherein two or more unit oligomers...
2018/0044674 NOVEL Zn-DPA COMPLEX COMPOUNDS AND siRNA DELIVERY SYSTEMS CONTAINING THE SAME
Provided herein are a novel Zn-DPA complex compound and an siRNA delivery system including the same as a transporter, the Zn-DPA complex compound including: a...
2018/0044673 METHODS FOR MODULATING MECP2 EXPRESSION
Disclosed herein are methods for decreasing MECP2 mRNA and protein expression. Such methods are useful to treat, prevent, or ameliorate MECP2 associated...
2018/0044672 Pericyte Long Non-Coding RNAs
The present invention provides novel non-coding RNAs (lncRNA) that were identified to be expressed in pericytes upon hypoxia. The lncRNA of the invention...
2018/0044671 DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TO P53 AND METHODS OF USE THEREOF
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders...
2018/0044670 GENE VECTOR
A gene vector for use in gene therapy comprising at least one miRNA sequence target operably linked to a nucleotide sequence having a corresponding miRNA in a...
2018/0044669 COMPOSITIONS FOR INHIBITING CHECKPOINT GENE EXPRESSION AND USES THEREOF
The present invention is directed to compounds, compositions, and methods useful for modulating PD1, PDL1, IDO1, LAG3, TIM3, CTLA4, IDO2, CEACAM1, OX40, and/or...
2018/0044668 MATE PAIR LIBRARY CONSTRUCTION
The present invention provides a novel method for ligating an adapter to a target polynucleotide and methods of generating a library of mate-pair ...
2018/0044667 Method for constructing nucleic acid single-stranded cyclic library and reagents thereof
Provided in the present invention are a method for constructing a nucleic acid single-stranded cyclic library and reagents thereof. The method comprises the...
2018/0044666 GENOME-ORIGINATED ARTIFICIAL NCRNA EXPRESSION LIBRARY AND METHOD OF PREPARING THE SAME
The present invention relates to an artificial ncRNA expression library and a method for preparing the same, and particularly the present invention relates to...
2018/0044665 METHOD OF MANUFACTURING PROTEIN ARRAY OR PEPTIDE ARRAY, METHOD OF IDENTIFYING FUNCTIONAL PROTEIN OR FUNCTIONAL...
There is provided a method of manufacturing a protein array or peptide array suitable for an efficient screening of a functional protein or functional peptide....
2018/0044664 METHODS OF SCREENIING FOR MICROORGANISMS THAT IMPART BENEFICIAL PROPERTIES TO PLANTS
The present invention relates to methods for the screening, identification and/or application of microorganisms and/or compositions of use in imparting...
2018/0044663 STRUCTURE ASSISTED DIRECTED EVOLUTION OF MULTIVALENT APTAMERS
Provided herein are methods and systems for structure-assisted evolution of multivalent aptamers using a single stranded DNA or single-stranded RNA...
2018/0044662 USE AND PRODUCTION OF CHD8+/- TRANSGENIC ANIMALS WITH BEHAVIORAL PHENOTYPES CHARACTERISTIC OF AUTISM SPECTRUM...
The invention involves inducing a plurality e.g., 3-50 or more mutations (e.g., any whole number between 3 and 50 or more of mutations, with it noted that in...
2018/0044661 CASSETTE FOR SAMPLE PREPARATION
Apparatuses for preparing a sample are disclosed herein. The apparatuses include a chamber, a first valve at least partially disposed in the first chamber, a...
2018/0044660 METHODS, COMPOSITIONS, AND KITS FOR GENERATING rRNA-DEPLETED SAMPLES OR ISOLATING rRNA FROM SAMPLES
The present invention provides methods, compositions, and kits for generating rRNA-depleted samples and for isolating rRNA from samples. In particular, the...
2018/0044659 METHODS AND KITS FOR FRAGMENTING DNA
A method of DNA fragmentation is provided. The method comprising incubating a semi-solid biological sample which comprises the DNA with an auxiliary...
2018/0044658 BIOFUNCTIONAL MATERIALS
The present invention relates to compositions and processes in the field of self-cleaning system using digestive proteins. One composition includes a...
2018/0044657 MICROSOMAL BIOREACTOR FOR SYNTHESIS OF DRUG METABOLITES
Reusable microsomal biocatalytic systems (bioreactors) constructed on carbon nanostructure modified electrodes are provided. The bioreactors comprise stable,...
2018/0044656 Treatment of Cellulosic Material and Enzymes Useful Therein
The present invention relates to the production of sugar hydrolysates from cellulosic material. The method may be used e.g. for producing fermentable sugars...
2018/0044655 HYPOCHLORITE RESISTANT CYANURIC ACID HYDROLASES AND METHODS OF USE THEREOF
The present invention relates to engineered cyanuric acid hydrolase enzymes that are resistant to hypochlorite and compositions and devices comprising such...
2018/0044654 Agarase, Composition Containing the Same, and Application thereof
The present invention provides a .beta.-agarase, a composition containing the same and applications thereof. The present .beta.-agarase provides the field a...
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