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Patent # Description
2018/0064852 BONE VOID FILLER PREPARATION SYSTEM
A method of recovering progenitor cells from bone marrow aspirate. A bone void filler preparation container is provided. The bone void filler preparation...
2018/0064851 ENGINEERED TISSUE CONSTRUCTS
A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate...
2018/0064850 Biocompatible implants for use in tendon therapy
The invention provides biocompatible implants ("scaffolds") for use in the treatment of tendon injury and/or modulation of the biomechanical properties of...
2018/0064849 CARTILAGE REGENERATIVE MATERIAL
An object of the invention is to provide a cartilage regenerative material that is capable of regenerating bone and cartilage using cells. Provided is a...
2018/0064848 USE OF RESECTED LIVER SERUM FOR WHOLE LIVER-ENGINEERING
The disclosure provides a method of using blood or fractions thereof, e.g., serum, obtained from a mammal subjected to liver surgery, for example, obtained...
2018/0064847 Implants with Wear Resistant Coatings and Methods
An implant comprises a substrate and a coating on a surface of the substrate, and the coating includes silicon nitride and has a thickness of from about 1 to...
2018/0064846 BIODEGRADABLE SINGLE-PHASE COHESIVE HYDROGELS
A process of preparing a biodegradable single-phase cohesive hydrogel composition includes preparing 2 to 5 hydrogels that are independently crosslinked so...
2018/0064845 PATELLAR IMPLANTS
A patellar implant including a base portion formed of a porous metallic material, a polymeric portion formed of a polymeric material and attached to the base...
2018/0064844 HEMOSTATIC PASTE WITH LIGHT-CURABLE FEATURE
A hemostatic paste comprising a hemostatic component; and a light-curable component.
2018/0064843 WOUND DRESSING
The present application is concerned with an improved wound dressing for use in the treatment of skin wounds with some level of exudation, especially for use...
2018/0064842 MATERIALS THAT SHRINK IN ONE DIMENSION AND EXPAND IN ANOTHER DIMENSION
A substrate includes a double-network polymer system including a cross-linked, covalently-bonded polymer and a reversible, partially ionicly-bonded polymer,...
2018/0064841 WOUND DRESSING
Embodiments disclosed herein provide compositions, methods, and uses for treating skin wounds, including chronic wounds such as venous ulcers. Certain...
2018/0064840 AIR PURIFIER
An air purifying operation is performed with a consideration for an influence of a purifying material on a person, and user's comfort and efficiency of the air...
2018/0064839 REPLACEABLE MULTILAYER BREATHING FILM-BASED AROMA CAPSULE AND AROMA-DIFFUSING HEATING DEVICE USING SAME
An aroma-diffusing heating device includes a heating base, and a aroma capsule put in the heating base in a replaceable manner and including a heat-transfer...
2018/0064838 AIR FRESHENING DEVICE
An air freshening device is provided. The device includes a water-based fragrance emitter including water, a water absorbing polymer and a fragrance...
2018/0064837 SYSTEMS AND METHODS FOR DETERMINING THE CLEANLINESS OF A SURFACE
Systems and methods for determining the cleanliness of a surface. Surface marking systems of the present disclosure can include a plurality of retroreflective...
2018/0064836 SYSTEMS, DEVICES, AND METHODS FOR GENERATING CHLORINE DIOXIDE
Methodologies, systems, and devices are disclosed for generating a chemical compound. A reaction chamber holds an amount of a precursor chemical, an activator...
2018/0064835 A CONTAINER, METHOD AND SYSTEM FOR STERILISING A MEDICAL DEVICE
The present invention relates to a container, a method and a system for sterilising a medical device. The invention is particularly, although not exclusively,...
2018/0064834 Targeted Enzymatic Degradation Of Quorum-Sensing Peptides
Methods and compositions for the treatment of biofilms and/or the inhibition of biofilm formation. In one embodiment, a biofilm is treated and/or biofilm...
2018/0064833 DEPLOYABLE ULTRAVIOLET LIGHT SANITIZING SYSTEMS AND METHODS
An ultraviolet (UV) light sanitizing system and method are configured to sanitize at least one surface within an enclosed space. The UV light sanitizing system...
2018/0064831 PSMA TARGETED NANOBUBBLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
A PSMA targeted nanobubble includes a membrane that defines at least one internal void, which includes at least one gas, and at least one PSMA ligand coupled...
2018/0064830 CONTRAST IMAGING AGENT WITH DISSOLVED GAS-EVOLVING FLUID
A diagnostic contrast composition includes a carrier fluid and a non-decaying gas-evolving fluid incorporated in the carrier fluid. The gas-evolving fluid has...
2018/0064829 FLUORESCENT BISPHOSPHONATE ANALOGS
Fluorescent probes based on N-heterocyclic bisphosphonates or their phosphonocarboxylate analogues are provided. The probes have variable spectroscopic...
2018/0064828 METHODS FOR THE DIAGNOSIS AND TREATMENT OF SJOGREN'S SYNDROME
The finding that patients with Sjogren's syndrome exhibit a statistically significant increase in expression of BMP6 in the salivary gland relative to healthy...
2018/0064827 MODULATION OF LIVER GENES
Described herein are compositions and methods for modulation of gene expression in the liver including modulation of PCSK9, TTR, SERPINA1, KLKB1 and/or HAO1.
2018/0064826 NON-VIRAL NANOPARTICLE-BASED DELIVERY SYSTEM
The present invention concerns a polymeric material for the production of a non-viral nanoparticle. The polymeric material comprises (i) a hydrophilic linear...
2018/0064825 ANTI-PD-L1 IMMUNOTOXIN FOR USE IN THERAPY
The present disclosure relates to a combination of an anti-PD-L1 (Programmed Cell Death 1 Ligand 1) with an `immunotoxin` for use in a method for treating a...
2018/0064824 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY
Conjugates which comprise a drug and a ligand which includes a first saccharide; wherein the conjugate is characterized in that, when the conjugate is...
2018/0064823 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS
The disclosure describes prodrugs and derivatives of prostaglandins, carbonic anhydrase inhibitors, kinase inhibitors, beta-adrenergic receptor antagonists and...
2018/0064822 METHOD INVOLVING 1-BENZOTRIAZOLYL CARBONATE ESTERS OF POLY(ETHYLENE GLYCOL)
The invention provides for preparing a polymer-active agent conjugate, the method comprising the steps of reacting an amino acid derivative with a biologically...
2018/0064821 SITE SPECIFIC CURCUMIN-POLYMER MOLECULAR COMPLEXES AND METHODS OF TREATING COLON DISEASES AND INFLAMMATION
Methods and materials relating to a medicament preparation comprising a curcuminoid component, such as curcumin, and a polymer component having a backbone...
2018/0064820 Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs,...
The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydromorphone ...
2018/0064819 Targeting Ligands
Described are novel targeting ligands that may be linked to compounds, such therapeutic compounds that are useful in directing the compounds to the in vivo...
2018/0064818 PHARMACEUTICAL COMPOSITION COMPRISING POLYPEPTIDE
Found out is a pharmaceutical composition that sustained-releases a drug for a long term after administration into the body. Provided is a pharmaceutical...
2018/0064817 Tamper Resistant Pharmaceutical Composition
Tamper resistant pharmaceutical composition and a process for the production of tamper resistant pharmaceutical composition are described herein. Tamper...
2018/0064816 CROSSLINKED HYALURONIC ACID COMPOSITIONS
Crosslinked hyaluronic acid compositions are disclosed herein. More specifically, the hyaluronic acid is crosslinked with a biologically active compound...
2018/0064815 PHOTOCROSSLINKED BIODEGRADABLE HYDROGEL
A photocrosslinked biodegradable hydrogel includes a plurality of natural polymer macromers cross-linked with a plurality of hydrolyzable acrylate cross-links....
2018/0064814 Naltrexone Long Acting Formulations and Methods of Use
The inventions described herein arose from unexpected discoveries made during clinical trials with a long acting formulation of naltrexone. As such, the...
2018/0064813 Oral Composition for Delivery of Drugs and Other Substances
The present disclosure provides for a composition which may be used for the solublization of an agent or the oral administration of an agent, the composition...
2018/0064812 MICROCAPSULE HAVING A MICROCAPSULE SHELL MATERIAL THAT IS RUPTURABLE VIA A RETRO-DIMERIZATION REACTION
A microcapsule encapsulates a payload agent, the microcapsule having a microcapsule shell material that is rupturable (e.g., to release the encapsulated...
2018/0064811 PHARMACEUTICAL COMBINATIONS COMPRISING CD33 ANTIBODIES AND DE-METHYLATING AGENTS
The present invention relates to pharmaceutical combinations CD33 antibodies and de-methylating agents for use in treating diseases like MDS and cancer,...
2018/0064810 USE OF RANK/RANKL ANTAGONISTS FOR TREATING NEUROMUSCULAR DISORDERS, GENETIC MYOPATHIES AND/OR NON GENETIC...
The present invention relates to uses and methods comprising one or more RANK/RANKL antagonists or of a pharmaceutical composition comprising one or more...
2018/0064809 ANTI-DC-HIL ANTIBODIES FOR CANCER DIAGNOSIS, PROGNOSIS AND THERAPY
The present disclosure is directed to antibodies that bind to DC-HIL on the surface of myeloid-derived suppressor cells, and thus antagonize the T cell...
2018/0064808 COMBINATION THERAPY OF BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5 AND CHEMOTHERAPEUTIC AGENTS
The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site...
2018/0064807 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular,...
2018/0064806 IMMUNOGENIC COMPOSITION
present application discloses an immunogenic composition comprising N. meningitidis capsular polysaccharides from at least one of serogroups A, C, W135 and Y...
2018/0064805 Method of Vaccination Comprising a Histone Deacetylase Inhibitor
A vaccination method is provided. The method comprises administering to a mammal a histone deacytelase inhibitor in conjunction with a vaccine that expresses...
2018/0064804 PORCINE EPIDEMIC DIARRHEA VIRUS STRAINS AND IMMUNOGENIC COMPOSITIONS THEREFROM
The present invention is directed to novel nucleotide and amino acid sequences of Porcine Epidemic Diarrhea Virus ("PEDV"), including novel genotypes thereof,...
2018/0064803 METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING...
Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are...
2018/0064802 Immunogenic Human Rhinovirus (HRV) Composition
Novel compositions useful as human rhino virus immunogens are provided. The compositions enable a host response to sites normally not recognized by a host.
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