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Patent # Description
2018/0064700 TESOFENSINE COMPOSITIONS
The present invention relates to tesofensine compositions, methods to prepare the same and uses thereof in preparing medicines for the prevention and treatment...
2018/0064699 METHOD OF TREATING HYPERTENSION
Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include...
2018/0064698 MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or...
2018/0064697 METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and...
2018/0064696 TRICYCLIC ANALOGUES, PREPARATION METHOD AND USES THEREOF
The present invention relates to a series of analogues of natural product Pyripyropene A represented by general formula I and a preparation method and use...
2018/0064695 METHODS OF ADMINISTERING PIRFENIDONE THERAPY
The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors...
2018/0064694 INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING FIBROSIS
A method of treating or preventing a fibrotic disease, disorder or condition includes administering to a subject in need of treatment a 15-PGDH inhibitor.
2018/0064693 Novel Dosing Regimens of Celgosivir for the Treatment of Dengue
Methods of treating a dengue virus (DENV) infection in a human subject, comprising administering to the human subject a compound of Formula (I), or...
2018/0064692 Anti-Fibrotic Pyridinones
Disclosed are pyridinone compounds, method for preparing these compounds, and methods for treating fibrotic disorders.
2018/0064691 Antibacterial compositions
Pharmaceutical compositions comprising cefepime or a pharmaceutically acceptable salt thereof, tazobactam or a pharmaceutically acceptable salt thereof, and...
2018/0064690 THIAZOLES AS MODULATORS OF RORyt
The present invention comprises compounds of Formula I ##STR00001## wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.7, R.sup.8, and ##STR00002## are...
2018/0064689 COMBINATION THERAPY OF HSP90 INHIBITORS AND PD-1 INHIBITORS FOR TREATING CANCER
A pharmaceutical composition comprising a PD-1 inhibitor and a Hsp90 inhibitor, or a tautomer, or a pharmaceutically acceptable salt thereof, wherein the Hsp90...
2018/0064688 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CANCER
The present invention relates to compositions and methods for the treatment of prostate cancer. The present invention relates to polyamides and prostate...
2018/0064687 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ELEVATED INDUCIBLE...
The invention relates to the new medical use of (4R)-2-(4-phenyl-2-oxopyrrolidin-1-yl)acetamide for the treatment of pathological conditions, including sepsis...
2018/0064686 INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS
The present invention is directed to indole derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of...
2018/0064685 CANCER TREATMENT COMPOSITION
The present invention relates to anti-cancer compositions based on extracts of a plant from the Mesembryanthemaceae family, in particular Mesembryanthemum...
2018/0064684 NINTEDANIB DIETHANESULFONATE SALT CRYSTAL AND PREPARATION METHOD AND USE THEREOF
The present invention relates to a nintedanib diethanesulfonate salt A-type crystal represented by formula (II), and also relates to a crystalline composition...
2018/0064683 COMPOSITION FOR PROMOTING HAIR GROWTH AND/OR HAIR RESTORATION CONTAINING PSORALIDIN
The present invention relates to a composition for promoting hair growth and hair restoration containing psoralidin or a derivative thereof, which can be...
2018/0064682 INHIBITORS OF LEUKOTRIENE-MEDIATED ACTIVITY FOR TREATING SIDE EFFECTS OF STATIN THERAPY
The present invention relates to the alleviation of adverse side effects resulting from statin therapy. The present invention further relates to the use of an...
2018/0064681 THERAPEUTIC COMBINATIONS OF CURCUMINOIDS AND FLAVONOIDS
Provided is a formulation and a method associated therewith for treating inflammation. The formulation includes therapeutically effective amounts of...
2018/0064680 DERIVATIVES OF KORORMICIN USEFUL AS ANTIBIOTICS
An antibiotic compound is of formula (I): ##STR00001## R.sup.1-R.sup.3, R.sup.5 and R.sup.6 are independently selected from H, alkyl group, substituted alkyl...
2018/0064679 METHOD FOR TREATING CANCER BASED ON LEVEL OF GLUCOCORTICOID RECEPTOR
The present invention provides methods and compositions for treating cancer with taxane-based therapy. The individuals may have a high level of glucocorticoid...
2018/0064678 USE OF CABAZITAXEL IN THE TREATMENT OF PROSTATE CANCER
The present invention relates to cabazitaxel for use in a method for treating an AR-V7-positive patient suffering from prostate cancer comprising determining...
2018/0064677 Methods of Treating an Overweight or Obese Subject
The invention generally relates to methods of treating an overweight or obese subject, and treating overweight- or obesity-related conditions. In certain...
2018/0064676 METHODS OF TREATING OR PREVENTING PROSTATE CANCER
In various embodiments, the present invention provides methods of treating and/or preventing prostate cancer and, in particular, the method comprising...
2018/0064675 ACTIVE FORMULATION FOR USE IN FEED PRODUCTS
Invention pertains to a free-flowing particulate powder including 2-90 wt. % of an active compound on a carrier, wherein the carrier has a D(v,0.1) of at least...
2018/0064674 Compositions and Methods for the Treatment of Fatty Acid Metabolism Disorders
Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject...
2018/0064673 PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DISEASES
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##
2018/0064672 ALLOSTERIC ACTIVATORS FOR TREATMENT OF PHENYLKETONURIA
A method of restoring activity in phenylalanine hydroxylase is provided. The method comprises exposing the phenylalanine hydroxylase to shikimic acid, a...
2018/0064671 Fixed Dose Combinations and Formulations Comprising ETC1002 and Ezetimibe and Methods of Treating or Reducing...
Disclosed herein are compositions comprising fixed doses of ETC-1002 and Ezetimibe. Also disclosed herein are methods for using fixed doses of ETC-1002 and...
2018/0064670 TREATMENT OF NERVOUS SYSTEM DISORDERS USING COMBINATIONS OF RXR AGONISTS AND THYROID HORMONES
Disclosed herein are methods of treating disease with a combination of a RXR agonist and a thyroid hormone.
2018/0064669 COMPOSITIONS AND METHODS OF PROVIDING THYROID HORMONE OR ANALOGS THEREOF
The present invention includes a pharmaceutical composition and method of making and using comprising one or more thyroid hormones or analogs thereof, wherein...
2018/0064668 METHODS AND COMPOSITIONS FOR IMPROVING MICROVASCULAR FUNCTION, SUPPRESSING CYCLOOXYGENASE ACTIVITY, REDUCING...
Methods of suppressing cyclooxygenase activity or reducing platelet aggregation of a mammal in need thereof by administering to a mammal in need thereof an...
2018/0064667 METHODS OF TREATING LACTOSE INTOLERANCE
Disclosed herein are methods for treating lactose intolerance, including compounds that may be specific or modulate PPAR.gamma. receptors.
2018/0064666 ENHANCED ATRA-RELATED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES, AUTOIMMUNE DISEASES, AND ADDICTION...
The invention features all-trans retinoic acid (ATRA)-related compounds capable of associating with Pin1 and methods of treating a proliferative disorder...
2018/0064665 N-PHENYL-N'-PHENOXYCARBONYL-PHENYLSULFONHYDRAZIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
The present invention relates to a N-phenyl-N'-phenoxycarbonyl-phenylsulfonhydrazide derivative with excellent inhibitory activity on PGE.sub.2 production, a...
2018/0064664 Compounds For Use In Treatment of Mucositis
The present invention provides methods for treating and/or preventing mucositis with one or more compounds, or pharmaceutically acceptable salts thereof,...
2018/0064663 EXTENDED RELEASE LIQUID COMPOSITIONS OF METFORMIN
The present invention relates to extended release liquid compositions of metformin. The extended release liquid compositions are in the form of suspensions or...
2018/0064662 NOVEL COMPOSITIONS AND USES OF METFORMIN AGENTS
Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., an anti-cancer, anti-fibrotic or anti-inflammatory therapy) are...
2018/0064661 Anise Flavored Medication
An anise flavored liquid medication. The liquid medication contains phenylephrine and an anethole analog that is substantially free of aldehyde groups. In one...
2018/0064660 AMINO ALCOHOL DERIVATIVES FOR THE TREATMENT OF DEMYELINATING PERIPHERAL NEUROPATHIES
The invention provides the use of compound of formula V or formula VI in the treatment of a demyelinating peripheral neuropathy: ##STR00001## Wherein X, R.sub.1,...
2018/0064659 AGENTS USEFUL FOR TREATING OBESITY, DIABETES AND RELATED DISORDERS
This invention provides methods of treatment diabetes and related conditions using idebenone and analogs thereof compounds 10, 11, 12 and DF-1176-178.
2018/0064658 Anti-cancer activity of (E)-1-(3',4'-Dimethoxyphenyl) butadiene
The present invention provides a method of using (E)-1-(3',4'-dimethoxyphenyl) butadiene to induce anti-tumorigenic effects in pancreatic carcinoma, ovarian...
2018/0064657 BISPHENOL ETHER DERIVATIVES AND METHODS FOR USING THE SAME
Compounds having a structure of Formula I, or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R.sup.1, R.sup.2, L.sup.1, L.sup.2,...
2018/0064656 TOPICAL PHARMACEUTICAL COMPOSITIONS
The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of ...
2018/0064655 Hydroxynorketamine Transdermal Patch
A transdermal patch comprising (2R,6R)-hydroxynorketamine or a conjugate thereof. The active agent may be in its free base form. The transdermal patch may...
2018/0064654 Sheet Packs And Methods For Treating Skin
A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin...
2018/0064653 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE
The present invention relates to solid oral dosage forms of Dimethyl fumarate. More specifically, the present invention relates to delayed release compositions...
2018/0064652 FORMULATIONS OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE
The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
2018/0064651 ULIPRISTAL ACETATE TABLETS
The invention relates to a pharmaceutical tablet for oral administration comprising ulipristal acetate together with the following excipients: at least one...
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