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Patent # Description
2018/0071319 Compositions and Methods for Preventing and Treating Heterotopic Ossification and Pathologic Calcification
The present invention is directed to compositions and methods for the prevention or treatment of treatment of heterotopic ossification, vascular calcification,...
2018/0071318 VITAMIN D RECEPTOR/SMAD GENOMIC CIRCUIT GATES FIBROTIC RESPONSE
The present disclosure provides compositions that include a nanoparticle and a compound that increases the biological activity of the vitamin D receptor (VDR)...
2018/0071317 USE OF AGENTS THAT ALTER THE PERITUMORAL ENVIRONMENT FOR THE TREATMENT OF CANCER
The invention relates to the use of agents that alter the peritumoral environment, specifically non-peptide NK1 receptor antagonists, for the treatment of...
2018/0071316 Compositions And Methods For Treating Dementia
The present disclosure is directed to methods, compositions, and kits for treating dementia.
2018/0071315 Methods of Treating Certain Depressive Disorders and Delirium Tremens
The disclosure provides a method of treating a patient having postpartum depression, premenstrual dysphoric disorder, menopausal depression, or delirium...
2018/0071314 DEHYDROANDROSTEROL AND METHODS OF USING THE SAME
A method of promoting muscle growth consisting of providing a dietary supplement containing an effective amount of dehydroandrosterol to a user. A composition...
2018/0071313 DRY EYE THERAPEUTIC AGENT COMPRISING NANDROLONE OR ESTER THEREOF OR METHENOLONE OR ESTER THEREOF AS AN ACTIVE...
An object of the present invention is to provide a novel dry eye therapeutic agent that demonstrates superior dry eye therapeutic effects, and from the...
2018/0071312 HIGH-STRENGTH TESTOSTERONE UNDECANOATE COMPOSITIONS
The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The...
2018/0071311 PHARMACEUTICAL DELIVERY SYSTEMS FOR HYDROPHOBIC DRUGS AND COMPOSITIONS COMPRISING SAME
A drug delivery system for oral administration of hydrophobic drugs with enhanced and extended absorption and improved pharmacokinetics is provided. In one...
2018/0071310 COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE AND RELATED DISORDERS
The present disclosure relates generally to methods and compositions for treating symptoms of Parkinson's disease and/or other movement disorders. More...
2018/0071309 FULVESTRANT COMPOSITIONS AND METHOD OF USE
Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and...
2018/0071308 METHODS FOR FAT REDUCTION
Disclosed herein are methods, compounds, and compositions for fat reduction, and in particular fat reduction without significant hair growth and/or additional...
2018/0071307 MEDICINAL COMPOSITION FOR ALLEVIATING ENDOMETRIOSIS AND COMPLICATIONS THEREOF AND USE OF THE SAME
The present invention relates to a medicinal composition for alleviating endometriosis and complications thereof and a use of the same. The medicinal...
2018/0071306 CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS
The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically acceptable salts or hydrates thereof of structural...
2018/0071305 ORAL FORMULATION AND SUSPENSION OF AN ONCOLOGY DRUG
Dry powder formulations for inhalation and their use in the treatment diseases and conditions. The formulation contains a uniform blend of a first spray-dried...
2018/0071304 Phenoxy Acetic Acids and Phenyl Propionic Acids as PPAR Delta Agonists
Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds...
2018/0071303 SYK INHIBITORS
The application provides methods reducing the side effects of chemotherapy and radiotherapy, including, hematopoietic toxicity, anemia, myelosuppression,...
2018/0071302 SYK INHIBITORS
The application provides methods of treating or reducing thrombocytopenia, leukopenia, anemia, or neutropenia in a patient in need thereof, comprising the step...
2018/0071301 USE OF NON-PEPTIDE NK1 ANTAGONISTS IN A PREDETERMINED DOSE FOR THE TREATMENT OF CANCER
Use of the non-peptide NK1 receptor antagonist, preferably Aprepitant, for the treatment of cancer in predetermined doses. The present invention also describes...
2018/0071300 METHOD OF TREATING CANCER
The present invention relates to methods of treating cancer by administering an EZH2 inhibitor or a pharmaceutical composition thereof to the subject in need...
2018/0071299 METHODS FOR TREATING PSYCHOSIS ASSOCIATED WITH PARKINSON'S DISEASE
The present invention provides a method of using arylpiperazine derivatives for treating psychosis associated with Parkinson's disease. The method comprises a...
2018/0071298 METHODS FOR TREATING ALZHEIMER'S DISEASE
The present invention provides a method of using arylpiperazine derivatives for treating behavioral and psychological symptoms in Alzheimer's disease patients....
2018/0071297 TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-ALPHA SYNTHESIS AND AS PDE4 INHIBITORS
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of...
2018/0071296 COMBINATION THERAPY COMPRISING AN INHIBITOR OF JAK, CDK, AND PIM
The present invention relates to a pharmaceutical combination which comprises (a) a JAK inhibitor compound, (b) a CDK inhibitor, and (c) a PIM kinase inhibitor...
2018/0071295 BRUTON'S TYROSINE KINASE INHIBITOR COMBINATIONS AND USES THEREOF
Disclosed herein are methods, compositions, and kits for treating a B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g....
2018/0071294 METHODS FOR THE TREATMENT OF HER2 AMPLIFIED CANCER
Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib.
2018/0071293 TEC FAMILY KINASE INHIBITOR ADJUVANT THERAPY
Described herein are methods and compositions comprising a covalent TEC family kinase inhibitor for use in adjuvant therapy, including adjuvant cancer therapy,...
2018/0071292 RIBOCICLIB TABLET
The present disclosure is directed to oral tablet of ribociclib including its salt(s). One embodiment of the present disclosure is directed to tablet of...
2018/0071291 Treatment of Respiratory Diseases
The present invention relates to compositions, methods and kits for the treatment of respiratory disease. In particular, the compositions, methods and kits are...
2018/0071290 Solid Pharmaceutical Formulation of PARP Inhibitors and Use Thereof
The present invention provides a solid pharmaceutical formulation of PARP inhibitors and its use thereof, and more specifically a solid dispersion powder...
2018/0071289 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER AND RELATED HYPERPROLIFERATIVE DISORDERS
The present invention relates to methods of treating a disease related to cell hyper-proliferation via administration of a therapeutically effective amount of...
2018/0071288 FUNCTIONAL CURE OF RETROVIRAL INFECTION
The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by...
2018/0071287 PHARMACEUTICAL COMPOSITIONS OF 7-(6-(2-HYDROXYPROPAN-2-YL)PYRIDIN-3-YL)-1-((TRANS)-4-METHOXYCYCLOHEXYL)-- ...
Provided herein are compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-- 3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one,...
2018/0071286 HETEROARYL PYRIDONE AND AZA-PYRODINE COMPOUNDS
Heteroaryl pyridone and aza-pyridone compounds are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for...
2018/0071285 SYSTEMS PHARMACOLOGY FOR TREATING OCULAR DISORDERS
A method of treating an ocular disorder in a subject includes administering to the subject subtherapeutic amounts of two or more agents that inhibit and/or...
2018/0071284 PREVENTING OR TREATING VIRAL INFECTION BY INHIBITION OF THE HISTONE METHYLTRANSFERASE EZH1 OR EZH2
Disclosed are methods of preventing or treating a viral infection of a host, the method comprising administering to the host an effective amount of an...
2018/0071283 Treatment of Vasomotor Symptoms
The invention relates to a method for the treatment of vasomotor symptoms comprising the administration of a therapeutically effective amount of flibanserin.
2018/0071282 Flibanserin for the Treatment of Urinary Incontinence and Related Diseases
The invention relates to the use of Flibanserin for the treatment or prevention of urinary incontinence and related diseases. In a further embodiment, the...
2018/0071281 TREATING CHRONIC RHINOSINUSITIS
Methods of treating chronic rhinosinusitis are provided. The methods include topically administering a combination of antifungal agents to the ostiomeatal...
2018/0071280 MODULATORS OF CELL DEATH PROCESSES
Provided are compositions and methods for modulating selective cell death mechanisms. More specifically, provided are methods and compositions for inducing in...
2018/0071279 METHODS AND COMPOSITIONS FOR TREATING DEGENERATIVE AND ISCHEMIC DISORDERS
Model systems have shown that shifting a cell's reliance from oxidative phosphorylation (OXPHOS) to glycolysis can protect against cell death. Exploiting the...
2018/0071278 ANTI-OVERINGESTION DOSAGE FORMS
Described herein are abuse deterrent oral pharmaceutical compositions, methods for making the same, and methods of treatement using such compositions. In...
2018/0071277 ORAL DOSAGE FORMS FOR OXYGEN-CONTAINING ACTIVE AGENTS AND OXYL-CONTAINING POLYMER
The disclosed invention is drawn to pharmaceutical tablets that provide delivery of active agents having at least three oxygen-containing groups, a tri-oxy...
2018/0071276 Combinations of Glycopyrrolate and Beta2 Adrenoceptor Agonists
A medicament comprising, separately or together (A) glycopyrrolate; and (B) either a compound of formula I ##STR00001## in free or salt or solvate form, wherein W,...
2018/0071275 TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD
Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a ...
2018/0071274 MEDICAL PRODUCT FOR REDUCING AND/OR ELIMINATING SYMPTOMS OF NICOTINE WITHDRAWAL
In essence, the present invention relates to a medical product including between about 94% and about 98% of a saline solution, preferably a normal saline...
2018/0071273 NUTRITIONAL COMPOSITIONS TO ENHANCE MITOCHONDRIAL ENERGY PRODUCTION
The present disclosure provides nutritional compositions comprising a synergistic effective amount of a NAD- pre-cursor in a combination with an ATP booster....
2018/0071272 NOVEL CHRONOTHERAPY BASED ON CIRCADIAN RHYTHMS
The invention includes a formulation of a therapeutic compound, wherein release of the therapeutic compound from the formulation coincides with peak or trough...
2018/0071271 Fumarate Analogs and Uses Thereof
Aspects of the present disclosure include compounds that find use for the treatment of a variety of autoimmune and inflammatory diseases and disorders....
2018/0071270 TABLETED COMPOSITIONS CONTAINING ATAZANAVIR
Disclosed are compressed tablets containing atazanavir sulfate, optionally with another active agents, e.g., anti-HIV agents, granules that contain atazanavir...
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