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Patent # Description
2018/0073090 LONG CAMPAIGN LIFE STAVE COOLERS FOR CIRCULAR FURNACES WITH CONTAINMENT SHELLS
Cast-iron and cast-copper stave coolers improve the campaign lives of furnaces with steel shelled vessels. Each stave cooler has a single rectangular body with...
2018/0073089 CHMERIC POLYPEPTIDES
The invention relates to recombinant clostridial neurotoxins which have been modified to improve their activation. In particular, the present invention relates...
2018/0073088 NOVEL HIGH-THROUGHPUT METHOD FOR QUANTIFICATION OF HBV CCCDNA FROM CELL LYSTATE BY REAL-TIME PCR
The present invention provides (1) a set of novel DNA primers that can be used for high efficient real-time qPCR of Hepatitis B virus (HBV) circular DNA...
2018/0073087 QUALITATIVE AND ABSOLUTE QUANTIFICATION KIT FOR DETECTING HEPATITIS B VIRUS CCCDNA
A composition for detecting hepatitis B virus cccDNA includes an upstream primer having the DNA sequence set forth in SEQ ID NO. 1, a downstream primer having...
2018/0073086 METHODS AND COMPOSITIONS FOR IDENTIFYING AND QUANTIFYING MICROBIAL DNA
This invention relates to methods and compositions for identifying microbial DNA in the tissues or body fluid samples of patients. More particularly, the...
2018/0073085 DETERMINING TUMOR ORIGIN
The disclosure provides methods for the use of gene expression measurements to classify or identify among 54 cancer types in samples obtained from a subject in...
2018/0073084 METHOD FOR PREDICTING RESPONSIVENESS TO PHOSPHATIDYLSERINE SYNTHASE 1 INHIBITOR
It is intended to develop a therapeutic strategy for specifically targeting cancer cells having the functional suppression of PSS2. The present inventors have...
2018/0073083 A MULTIGENE ASSAY
An in vitro method of determining the type of a fibroepithelial tumour of the breast in a biological sample is provided. The method comprises the steps of...
2018/0073082 DUMBBELL-STRUCTURE OLIGONUCLEOTIDE, NUCLEIC ACID AMPLIFICATION PRIMER COMPRISING SAME, AND NUCLEIC ACID...
The present invention relates to a dumbbell-structure oligonucleotide (DSO), a nucleic acid amplification primer comprising the same, and a nucleic acid...
2018/0073081 Method for Predicting Prognostic Results of Diseases
The invention is directed to a method to predict prognostic results for diseases including acute myeloid leukemia (AML) by analyzing novel markers which...
2018/0073080 METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING
The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a sample of...
2018/0073079 COMPOSITIONS AND METHODS FOR IDENTIFYING DEPRESSIVE DISORDERS
Provided herein are compositions, kits, and methods for the identification of depressive disorders. In particular, provided herein are compositions, kits, and...
2018/0073078 RNF41 AS A BIOMARKER PREDICTING RESPONSE TO LENALIDOMIDE IN NON-DEL(5Q) MDS
Disclosed herein is a method of using erythroid expression levels of RNF41 as a predictive biomarker for responsiveness to lenalidomide (LEN) in patients with...
2018/0073077 METHODS AND COMPOSITIONS FOR PREDICTION OF THERAPEUTIC EFFICACY OF CANCER TREATMENTS AND CANCER PROGNOSIS
The invention generally relates to methods and compositions for the prediction of therapeutic efficacy of cancer treatments and the prognosis of cancer. The...
2018/0073076 METHODS AND COMPOSITIONS FOR SCREENING AND TREATING DEVELOPMENTAL DISORDERS
This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using...
2018/0073075 Risk Factors of Cigarette Smoke-Induced Spriometric Phenotypes
The technology provided herein relates to the SNPs identified as described herein, both singly and in combination, as well as to the use of these SNPs, and...
2018/0073074 SYSTEMS AND METHODS FOR SEQUENCING IN EMULSION BASED MICROFLUIDICS
Methods, libraries, and kits for nucleotide sequencing are provided.
2018/0073073 METHODS AND COMPOSITIONS FOR LABELING TARGETS AND HAPLOTYPE PHASING
Disclosed herein are methods for estimating the copy number of a target chromosome in a sample. In some embodiments, the methods include: partitioning a sample...
2018/0073072 NANOPORE-BASED NUCLEIC ACID ANALYSIS WITH MIXED FRET DETECTION
Various methods, systems and devices for optical detection and analysis of polymers, such as polynucleotides, using nanopores, e.g., for determining sequences...
2018/0073071 NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION OF TAG MOLECULES
This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide...
2018/0073070 SYSTEM AND METHOD FOR COPY NUMBER VARIATION ANALYSIS
The present invention relates to a method and system for determining Copy Number Variations (CNVs) in a genomic test sample including target amplicons and a...
2018/0073069 NUCLEIC ACID AMPLIFIER, CARTRIDGE FOR NUCLEIC ACID AMPLIFICATION AND NUCLEIC ACID AMPLIFICATION METHOD
A nucleic amplifier is provided to reduce an amplification efficiency drop even with a short cycle time. In the nucleic amplifier, the denaturation phase of...
2018/0073068 HAIRPIN-MEDIATED AMPLIFICATION METHOD
In some embodiments, the amplification method may comprise producing a reaction mix comprising: a nucleic acid sample, a polymerase, nucleotides, a forward...
2018/0073067 Lyophilized integrated composition for storage and manipulation of pyrophosphorolysis activated polymerization
The invention provides a method for lyophilizing integrated composition of pyrophosphorolysis activated polymerization (PAP) in an aqueous solution. It also...
2018/0073066 Method for Blocking miRNA
A blocking nucleic acid for use in reducing the abundance of a non-target micro-RNA (miRNA) in an miRNA library is provided, including: a single-stranded...
2018/0073065 STRUCTURED SUBSTRATES FOR IMPROVING DETECTION OF LIGHT EMISSIONS AND METHODS RELATING TO THE SAME
Structured substrate including (a) a plurality of nanoparticles distributed on a solid support, (b) a gel material forming a layer in association with the...
2018/0073064 METHODS FOR PERFORMING MULTIPLEXED REAL-TIME PCR
The present invention describes methods for performing higher multiplexed real-time PCR for detection and quantitation of target nucleic acids using tagged...
2018/0073063 REUSABLE MICROARRAY COMPOSITIONS AND METHODS
The present application provides a reusable microarray comprising a plurality of immobilized oligonucleotide probes each having one or more nucleotides that...
2018/0073062 COMPOSITIONS AND METHODS FOR IDENTIFYING ENDOGENOUS DNA-DNA INTERACTIONS
Provided herein are compositions and methods for identifying endogenous DNA-DNA interactions. In particular, compositions and methods are provided for...
2018/0073061 LABEL-FREE METHODS FOR ISOLATION AND ANALYSIS OF NUCLEIC ACIDS ON SOLID PHASE DEVICE
Methods and system for the isolation and/or analysis of nucleic acids on a solid phase device comprising (i) incubating a nucleic acid sample with Dimethyl...
2018/0073060 SIMULTANEOUS DETECTION OF OLIGONUCLEOTIDES, A KIT AND A USE RELATED THERETO
In a first aspect, the invention relates to a method for detecting at least two distinct oligonucleotides of equal length in parallel from one biological...
2018/0073059 COMPOSITIONS AND METHODS FOR DETECTING NUCLEIC ACID FROM MOLLICUTES
Compositions, reaction mixtures, kits and methods used in amplifying and detecting nucleic acids from various species of the class Mollicutes. Particular...
2018/0073058 PRIMER PAIR, KIT AND METHOD FOR DETECTING ANAPLASMA PLATYS
Primer pair, kit and method for detecting Anaplasma platys are disclosed. The primer pair includes a forward primer and a reverse primer, and the kit includes...
2018/0073057 METHODS FOR CONSTRUCTING CONSECUTIVELY CONNECTED COPIES OF NUCLEIC ACID MOLECULES
Methods for constructing consecutively connected and optionally truncated copies of nucleic acid molecules are disclosed. Consecutively connected copies of...
2018/0073056 METHODS FOR PERFORMING MULTIPLEXED PCR
The present invention describes methods for performing higher multiplexed PCR for detection and quantitation of target nucleic acids using tagged hydrolysis...
2018/0073055 NUCLEIC ACID EXTRACTION AND AMPLIFICATION CONTROLS AND METHODS OF USE THEREOF
Nucleic acid reagents and corresponding methods of using the same for monitoring and evaluating nucleic acid extraction and amplification reactions.
2018/0073054 FLUORESCENCE DETECTION DEVICE
The fluorescence detection device includes an illumination module and a detection module. The illumination module includes a light source and a first filter....
2018/0073053 PCR Method
A method for generating amplicon constructs of a target sequence is disclosed, the method comprising providing a target sequence; an oligonucleotide probe,...
2018/0073052 Single Domain Antibodies that Bind to Human CD20
Mesoporous sorbents are effective for storing and transporting nucleic acids. In particular, two ethane-bridged silica sorbents with amine functionalities are...
2018/0073051 THERMAL REACTION DEVICE AND METHOD FOR USING THE SAME
A method for carrying out nucleic acid amplification reactions using a microfluidic device is described. Amplification primers and other amplification reagents...
2018/0073050 EXTRACELLULAR DITERPENE PRODUCTION
The present invention relates to a method for the production of a diterpene or a glycosylated diterpene, which method comprises: a. fermenting a recombinant...
2018/0073049 Method of converting RB to RD by using cutinase under stepwise changing temperatures
The present invention provides a method to produce RD by using a cutinase to catalyze the esterification of RB under stepwise cooling temperatures, which is...
2018/0073048 PROCESS FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERIAL AND FERMENTATION OF SUGARS
The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally...
2018/0073047 BIOCATALYTIC PRODUCTION OF L-FUCOSE
The present invention relates to biocatalytic methods, comprising purely enzymatic, mixed enzymatic-fermentative and purely fermentative methods, for the...
2018/0073046 PRODUCTION OF FATTY ACID ESTOLIDES
It has been found that esterification of a hydroxy-fatty acid by a lipase can be coupled with oleate hydratase (OHase) generation of that hydroxy-FA from an...
2018/0073045 Polymer Grade Lactic Acid Monomer Production Bacteria and Construction Method thereof and Technology for...
Disclosed are very high optically pure D- and L-lactic acid fermentation production strains and construction methods thereof and the method for preparing very...
2018/0073044 PROCESS FOR MANUFACTURING PROPIONATE PRODUCTS
A process for manufacturing propionate products through fermentation, including the steps of fermenting a carbon source selected from sugars and lactate in a...
2018/0073043 Production of Cannabidiolic Acid in Yeast
Exemplary embodiments provided herein include genetically engineering microorganisms, such as yeast or bacteria, to produce cannabinoids by inserting genes...
2018/0073042 CO HYDRATASE AND METHOD FOR PRODUCING FORMATE USING THE SAME
Provided are CO hydratase and a method for producing formate using the same, and more specifically, to CO hydratase which is a novel enzyme which is produced...
2018/0073041 PROCESSES OF PRODUCING FERMENTATION PRODUCTS
The invention relates to processes of producing a fermentation product, comprising liquefying a starch containing material with an alpha-amylase; ...
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