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Patent # Description
2018/0079745 PYRAZOLONE COMPOUNDS AND USES THEREOF
The invention disclosed herein is directed to compounds of Formula I [Formula should be entered here] and pharmaceutically acceptable salts thereof, which are...
2018/0079744 METHOD OF PREPARATION FOR LEDIPASVIR AND DERIVATIVE THEREOF, AND INTERMEDIATE COMPOUND FOR PREPARATION OF...
Methods of preparing Ledipasvir and derivatives thereof, and intermediate compounds used in the preparation of Ledipasvir are provided. Specifically, a method...
2018/0079743 FACTOR XIa INHIBITORS
The present invention provides a compound of Formula (I); and pharmaceutical compositions comprising one or more said compounds, and methods for using said...
2018/0079742 Deuterium-Substituted Pyridin- And Pyrimidin-2-yl-Methylamine Compounds
Described are deuterium-substituted pyridin- and pyrimidin-2-yl-methylamine compounds of structural Formula (I), which are agonists of 5-hydroxytryptamine...
2018/0079741 PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND
The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine ...
2018/0079740 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES
Compounds of the formula (I) wherein the substituents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which...
2018/0079739 Manufacturing Method For and Insecticidal Compositions Comprising Thiocyclam Hydrochloride
A method for manufacturing an insecticidal compound and insecticidal compositions comprising the insecticidal compound and methods of use are presented herein....
2018/0079738 AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR,...
Provided are: an aromatic sulfonium salt compound which exhibits low corrosion to a substrate and excellent photolithographic characteristics and is thus...
2018/0079737 FUMAGILLOL SPIROCYCLIC COMPOUNDS AND FUSED BICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME
Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods...
2018/0079736 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME
Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g.,...
2018/0079735 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME
A process for producing acesulfame potassium, the process comprising the steps of providing a cyclizing agent composition comprising a cyclizing agent and a...
2018/0079734 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME
Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of providing a crude acesulfame...
2018/0079733 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME
Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of forming a cyclic sulfur trioxide...
2018/0079732 AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR...
A novel asymmetric diamine, diamino-2-(benzothiazole-2-yl)diphenyl ether, derivatives therefor, and an intermediate for the compound such as ...
2018/0079731 AXIALLY CHIRAL ISOMERS, AND PREPARATION METHODS THEREFOR AND PHARMACEUTICAL USES THEREOF
Disclosed are two axially chiral isomers and pharmaceutically available salts thereof, preparation method therefor, and pharmaceutical use of the two axially...
2018/0079730 ANTI-PCSK9 COMPOUNDS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF CARDIOVASCULAR DISEASES
Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these...
2018/0079729 GHRELIN 0-ACYL TRANSFERASE INHIBITORS
The present invention provides novel GOAT inhibitors and their salts and pharmaceutical compositions thereof.
2018/0079728 USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
Salts of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium, method of preparation thereof and use in the treatment of cardiovascular disease.
2018/0079727 9-MEMBERED FUSED RING DERIVATIVE
The purpose of the present invention is to provide novel compounds having ACC2 selective inhibitory activity. In addition, the present invention provides a...
2018/0079726 BENZIMIDAZOLE DERIVATIVES AND USE THEREOF
The invention provides compounds that are useful as sodium channel blockers. In one aspect, the invention provides compounds of Formula I: ##STR00001## and...
2018/0079725 METHOD FOR PRODUCING PYRAZOLE DERIVATIVE
The invention relates to a production method of pyrazole derivative (6) by reacting compound (5) with an oxidant. ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3,...
2018/0079724 SULFONIC ACID DERIVATIVE COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR,...
Provide are: a sulfonic acid derivative compound which has high absorbance for light having a wavelength of 365 nm and exhibits high solubility in organic...
2018/0079722 HYDROBROMIDE SALT OF N-(4-CHLORO-2-HYDROXY-3-((3S)-3-PIPERIDINYLSULFONYL)PHENYL-N'-(3-FLUORO-2- ...
A compound which is the hydrobromide salt of N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(3-fluoro-- 2-methylphenyl)urea, compositions,...
2018/0079721 ORGANIC ELECTROLYTE COMPOUNDS FOR REDOX-FLOW BATTERIES
The present invention relates to redox electrolyte compounds. The present invention further relates to a redox-flow battery wherein one of the catholyte and...
2018/0079720 NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC...
Compounds of formula (I): ##STR00001## wherein R1 and R2 represent hydrogen or deuterium atoms; R3 represents a hydrogen atom or a --COOH, a --OH or a...
2018/0079719 NOVEL THIOL COMPOUND COMPOSITION FOR OPTICAL MATERIAL
According to the present invention, it is possible to provide a polythiol composition, which comprises a polythiol (A) represented by formula (1) and a thiol...
2018/0079718 Mixed Decyl Mercaptans Compositions and Methods of Making Same
Compositions comprising branched C.sub.10 mercaptans selected from the group consisting of 5-methyl-1-mercapto-nonane, 3-propyl-1-mercapto-heptane,...
2018/0079717 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES
The present invention relates to a new process for preparing 3-chloro-2-vinylphenylsulfonate derivatives.
2018/0079716 CYCLIC PROCESS FOR PRODUCING TAURINE
There is disclosed a process for producing taurine from ammonium isethionate by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or...
2018/0079715 METHOD FOR PRODUCING ALKYLAMINE DERIVATIVE AND ITS PRODUCTION INTERMEDIATE OF ALKYLAMINE DERIVATIVE
A method for producing an alkylamine derivative having a urea bond represented by formula (I), or a salt thereof, comprises the following steps (a) and (b),...
2018/0079714 NOVEL CONFIGURATION AND ITS USE IN PROCESS FOR SYNTHESIS OF ALKYL CARBAMATES FROM ALKYL ALCOHOL AND UREA IN A...
The present invention discloses an improved catalyst free process for synthesis of alkyl carbamates in an integrated system comprising a tubular reactor and a...
2018/0079713 THERMAL CONVERSION VESSEL USED IN A PROCESS FOR AMIDIFICATION OF ACETONE CYANOHYDRIN
The invention relates to a thermal conversion vessel (200) used during amidification step of acetone cyanohydrin (ACH), in the industrial process for...
2018/0079712 INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE FOR THE TREATMENT OF CANCER
There are disclosed compounds of formula (I) that modulate or inhibit the enzymatic activity of indoleamine-2,3-dioxygenase (IDO), pharmaceutical compositions...
2018/0079711 GLAUCOCALYXIN A DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF
Provided is a glaucocalyxin A derivative, or salt thereof, as represented by the formula (I), a method for preparation of said glaucocalyxin A derivative, and...
2018/0079710 AMINE FOR RAPID-CURING EPOXY RESIN COMPOSITIONS
An amine of formula (I) which is particularly suitable for use as a curing agent for epoxy resins. The amine of formula (I) is devoid of non-incorporable toxic...
2018/0079709 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS
The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and...
2018/0079708 PROCESS FOR PRODUCING FLUORINATED ELECTROLYTE SOLVENT
The invention provides a method for producing halogenated carbonates, the method comprising reacting a halogenated alcohol or diol with a solid source of...
2018/0079707 NEW BI-AROMATIC PROPYNYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM AND USES THEREOF
The invention relates to new compounds of the general formula (I): ##STR00001## as well as the use thereof in pharmaceutical compositions intended for use in...
2018/0079706 IMPROVED PROCESS FOR PRODUCING (METH)ACRYLIC ACID
The invention is directed to a process for recovering/purifying (meth)acrylic acid which does not use azeotropic solvent and is based on the use of two columns...
2018/0079705 METHOD FOR PURIFICATION OF AN AROMATIC DIACID OR THE CORRESPONDING ANHYDRIDE
A method of purifying a stream having an aromatic carboxy-aldehyde and an aromatic acid or the corresponding anhydride is described. The method includes...
2018/0079704 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS
New methods of preparing bridged bi-aromatic ligands are disclosed. The methods employ direct di-ortho-lithiation of aromatic rings of bridged protected...
2018/0079703 METHOD FOR CULTIVATION OF MONARDA FISTULOSA FOR PRODUCTION OF THYMOQUINONE
A method for cultivating Monarda fistulosa for production of thymoquinone includes planting seeds at rates between about 2.5 and about 5 pounds per acre,...
2018/0079702 PROCESS FOR THE SEPARATION OF CLYCOLS
The invention provides a process for the separation of MEG and 1,2-BDO from a first mixture comprising MEG and 1,2-BDO in a weight ratio of at least 10:1...
2018/0079701 PROCESS FOR INCREASING XYLENE ISOMER TO BENZENE RATIO
Apparatuses and processes are provided for regulating C7 and C8 feed to an aromatics complex to increase the ratio of a selected xylene isomer to benzene...
2018/0079700 INTEGRATED C3 - C4 HYDROCARBON DEHYDROGENATION PROCESS
An integrated process, suitable for use in a new or retrofitted plant, produces an olefin or di-olefin via the dehydrogenation of an appropriate C3-C4...
2018/0079699 INTEGRATED PROPANE DEHYDROGENATION PROCESS
Processes and systems for the integrated production of propylene and an alkylate, such as cumene, may include feeding a hydrocarbon feedstock containing...
2018/0079698 Catalyst Comprising a Phosphorous Modified Zeolite and Having Partly an Alpo Structure
The present invention relates to a catalyst comprising a phosphorus modified zeolite, said phosphorus modified zeolite having partly an ALPO structure,...
2018/0079697 Solid-rocket Propellants
Solid-fuel rocket propellants comprising an oxidizer, an oxophilic metal-halophilic metal formulation, and a binder are described herein. Further described are...
2018/0079696 REACTIVE GAS SHAPED CHARGE AND METHOD OF USE
A perforating system including a perforating gun having a perforating gun body housing shaped charges oriented outwardly from the gun body and connected to a...
2018/0079695 OBSCURANT EMISSION SYSTEMS AND METHODS
An obscurant-emitting composition may comprise an oxidizer comprising a cation comprising at least one of an alkali metal or an alkaline earth metal, and an...
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