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Patent # Description
2018/0086865 RAFT AGENT, POLYMERIZATION METHOD, POLYMER, RUBBER MIXTURE, AND USE THEREOF
Disclosed are RAFT agents, a method of polymerizing alkenes, dienes, vinyl compounds, and/or vinylidene compounds using at least one RAFT agent, polymers...
2018/0086864 MEDICAL INSTRUMENT, FLUORINE-CONTAINING CYCLIC OLEFIN POLYMER, FLUORINE-CONTAINING CYCLIC OLEFIN POLYMER...
Medical instrument including a substrate using a fluorine-containing cyclic olefin polymer containing a structural unit represented by General Formula (1), in...
2018/0086863 SULFONATION PROCESS
Provided is a method for reacting a resin with sulfuric acid comprising the step of heating a reaction mixture to a temperature of 80.degree. C. or higher,...
2018/0086862 PARAFFIN INHIBITORS, AND PARAFFIN SUPPRESSANT COMPOSITIONS AND METHODS
Disclosed are paraffin inhibitors, paraffin suppressant compositions, and methods of making and using them. The paraffin inhibitors comprise polymers of a...
2018/0086861 PRODUCTION PROCESS FOR PRODUCING WATER-ABSORBENT POLYMER PARTICLES AND BELT DRYER
A production process for production of water absorbing polymer particles, including drying an aqueous polymer gel in a belt drier with a conveyor belt having a...
2018/0086860 LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION, AND METHOD FOR...
The present invention relates to a ligand compound, catalyst system for olefin oligomerization, and a method for oligomerizing olefins using the same. The...
2018/0086859 Supported Catalyst Systems and Processes for Use Thereof
This invention relates to a supported catalyst system and process for use thereof. In particular, the catalyst system includes a pyridyldiamido transition...
2018/0086858 POLYMERIZATION OF MICHAEL-TYPE MONOMERS
A process for precision polymerization is described using a system of a Lewis acid, a Lewis base and a Michael-type monomer that can form a frustrated triple,...
2018/0086857 PROCESS FOR ADDING A CHAIN SHUTTLING AGENT
A process to form a block copolymer comprising two or more regions or segments of differentiated polymer composition or properties, including feeding a first...
2018/0086856 Method and apparatus for the preparation of a polyolefin
A method (100) is proposed for the preparation of a polyolefin from olefin monomers, wherein the olefin monomers are subjected to one or more polymerisation...
2018/0086855 Compound, Modified Polymer, Rubber Composition, Tire, And Conveyor Belt
The present invention is to provide a compound that can provide a modified polymer exhibiting excellent rigidity, wear resistance, and low heat build-up when...
2018/0086854 EXTRACTION OF POLYISOPRENE WITH HIGH MOLAR MASS
The invention relates to a method for extracting high-quality polyisoprene by grinding plants via rotary shearing using a device comprising at least one rotor...
2018/0086853 METHOD FOR SULFATING GLYCOSAMINOGLYCAN
An object of the present invention is provide a method for sulfating a glycosaminoglycan in a solution of a non-organic solvent. In the present invention,...
2018/0086852 Hyaluronic Acid Derivative and Manufacturing Method Therefor and Cosmetics, Food Composition, and...
A method for manufacturing a hyaluronic acid derivative includes a step of reacting a carboxymethyl group-containing modified hyaluronic acid and/or a salt...
2018/0086851 PRODUCTION OF CARBOXYLATED NANOCELLULOSES
The present disclosure provides methods for producing carboxylated nanocelluloses. Compared with conventional methods, the methods of the present disclosure...
2018/0086850 PROTEIN-NANOPARTICLE CONJUGATE PURFICATION METHODS
Methods and kits for purifying protein-nanoparticle conjugates are provided. In some embodiments, a multimodal medium having a size exclusion mode and a...
2018/0086849 BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In...
2018/0086848 ANTIBODIES AGAINST PHOSPHORYLCHOLINE
The present invention relates to an antibody or antibody fragment capable of binding to phosphorylcholine and/or a phosphorylcholine conjugate, wherein the...
2018/0086847 ANTIBODIES BINDING TO PHOSPHORYLCHOLINE (PC) AND/OR PC CONJUGATES
The present invention relates to an antibody or antibody fragment capable of binding to phosphorylcholine and/or a phosphorylcholine conjugate, wherein the...
2018/0086846 ANTIGEN BINDING MOLECULES AND METHODS OF USE THEREOF
Isolated antigen binding molecules that specifically bind to an anti-CD19 scFv comprising SEQ ID NO: 1 are provided. The antigen binding molecules can be used...
2018/0086845 NUCLEIC ACIDS ENCODING ANTIBODIES TO MATRIX METALLOPROTEINASE 9
The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind...
2018/0086844 ANTIBODIES AGAINST MAMMAL SECRETED KLOTHO PROTEIN
Antibodies against mammal secreted Klotho protein The invention relates to new antibodies raised against mammal secret isoform of Klotho protein. There are...
2018/0086843 ANTI-CD22 ANTIBODIES
Anti-CD22 antibodies, including isolated nucleic acids that encode at least one such anti-CD22 antibody, vectors, host cells, transgenic animals or plants, and...
2018/0086842 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BONE METASTASES
The present disclosure relates to methods and pharmaceutical compositions for the treatment of bone metastases. In particular, the present disclosure relates...
2018/0086841 ANTI-CD27 ANTIBODIES
The present invention relates to anti-CD27 antibodies, as well as use of these antibodies in the treatment of diseases such as cancer and infectious disease.
2018/0086840 ANTIBODIES THAT BIND TO TL1A AND THEIR USES
The present invention relates to antibodies or fragments thereof that bind to TL1A. More specifically, the present invention relates to an antibody or fragment...
2018/0086839 ANTI-IL-6/IL-6R ANTIBODIES AND METHODS OF USE THEREOF
This invention provides fully human monoclonal antibodies that recognize the IL-6/IL-6R complex. The invention further provides methods of using such...
2018/0086838 ANTI-CXCR3 ANTIBODIES AND METHODS OF USE THEREOF
The present disclosure provides anti-CXCR3 antibodies and methods of using the antibodies to diagnose and/or treat CXCR3-associated disorders such as diabetes...
2018/0086837 BISPECIFIC CXCR4-CD4 POLYPEPTIDES WITH POTENT ANTI-HIV ACTIVITY
The present invention relates to bispecific polypeptides that are directed against the cellular receptor CD4 as well as a cellular co-receptor for HIV. Said...
2018/0086836 ANTIBODIES THAT BIND TO CCR6 AND THEIR USES
The present invention relates to antibodies or fragments thereof that bind to CCR6. More specifically, the present invention relates to an antibody or fragment...
2018/0086835 LIGANDS THAT BIND TGF-BETA RECEPTOR II
The disclosure provides an anti-TGFbetaRII immunoglobulin single variable domain. Suitably, an anti-TGFbetaRII immunoglobulin single variable domain in...
2018/0086834 ANTI-CD303 MONOCLONAL ANTIBODIES
The invention relates to chimeric or humanised anti-CD303 antibodies to nucleic acids coding for the heavy and light chains of these antibodies, expression...
2018/0086833 INTEGRIN BETA7 ANTAGONISTS AND METHODS OF TREATING CROHN'S DISEASE
Methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including Crohn's disease are provided. Also provided are...
2018/0086832 HLA-RESTRICTED EPITOPES ENCODED BY SOMATICALLY MUTATED GENES
Mutant epitopes encoded by cancer genes are virtually always located in the interior of cells, making them invisible to conventional antibodies. We generated...
2018/0086831 PROTEIN-BASED T-CELL RECEPTOR KNOCKDOWN
The invention relates to protein-based T-cell receptor knockdown, and its use in T-cell therapies.
2018/0086829 ANTI-LILRB ANTIBODIES AND THEIR USE IN DETECTING AND TREATING CANCER
The present disclosure is directed to antibodies binding to LILRBs and methods of detecting and treating cancer therewith.
2018/0086828 SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
Site-specific antibody-drug conjugates are described, in particular conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the...
2018/0086827 THERAPEUTICS AND METHODS OF TREATING FIBROPROLIFERATIVE DISEASES
A method of treating a condition in a mammal comprising: administering a pharmacologically effective amount of a therapeutic; wherein the therapeutic one of...
2018/0086826 MECHANICALLY INTERLOCKING COMPLEXES
Provided herein are functionalized monoclonal antibodies (mAbs) including antibody fragments, including those where a Fab-binding molecule (Fab binding moiety)...
2018/0086825 ANTI-ANG2 ANTIBODY
An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes...
2018/0086824 METHOD OF TREATING NEPHROPATHY
The present disclosure provides a method of treating diabetic nephropathy in a subject suffering from diabetic nephropathy, the method comprising administering...
2018/0086823 ANTI-PLASMODIUM PARASITE ANTIBODIES
The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium...
2018/0086822 METHOD FOR REDUCING THE IMMUNE RESPONSE TO A BIOLOGICALLY ACTIVE PROTEIN
A new use of a molecule comprising at least one moiety which is a biologically active protein and at least one moiety capable of binding to a serum albumin of...
2018/0086821 HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM
Antibodies, particularly human antibodies, are disclosed having activity in treatment of demyelinating diseases and diseases of the central nervous system....
2018/0086820 ENANTIOPURE HAPTENS FOR NICOTINE VACCINE DEVELOPMENT
The invention provides chiral haptens (-)-3'-AmNic and (-)-N4N for use in generating antibodies in a patient specific for (-)-nicotine. The haptens can be...
2018/0086819 HUMAN CYTOMEGALOVIRUS NEUTRALIZING ANTIBODIES AND USE THEREOF
The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and...
2018/0086818 COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNODEFICIENCY
The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the...
2018/0086817 Preventing, Treating or Arresting Alzheimer's, Stroke, Cardiovascular and other Amyloid Related Diseases
This invention provides systems and methods for arresting, treating and/or preventing diseases caused by amyloid deposits of proteins. This invention teaches...
2018/0086816 LONG-LIVED POLYNUCLEOTIDE MOLECULES
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of long-lived polynucleotides, primary transcripts and...
2018/0086815 T1R TASTE RECEPTORS AND GENES ENCODING SAME
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G...
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