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Patent # Description
2018/0092912 LIPOSOMAL CIPROFLOXACIN FORMULATIONS WITH ACTIVITY AGAINST NON-TUBERCULOUS MYCOBACTERIA
Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of...
2018/0092911 OTIC GEL FORMULATIONS FOR TREATING OTITIS MEDIA
Disclosed herein are methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an...
2018/0092910 INJECTABLE FORMULATION
An object of the present invention is to provide a sustained-release injectable preparation which is in a medication administration form that can provide the...
2018/0092909 LURASIDONE NOVEL DOSAGE REGIMENS AND USE THEREOF FOR THE TREATMENT, PREVENTION, AND/OR MANAGEMENT OF AT LEAST...
Dosage regimens for at least one compound chosen from lurasidone and pharmaceutically acceptable salts, solvates, clathrates, and stereoisomers thereof are...
2018/0092908 SMALL MOLECULE OXIDIZERS OF PDI AND THEIR USE
The present invention provides a method for treating or ameliorating the effects of a neurodegenerative disorder in a subject in need thereof. The method...
2018/0092907 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS
Provided is a superior, novel heterocyclic compound with improved solubility in oil such as sesame oil and benzyl benzoate, which has a broader treatment...
2018/0092906 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically,...
2018/0092905 TRANSDERMAL DELIVERY SYSTEM
The invention relates to transdermal therapeutic system for the transdermal administration of buprenorphine, comprising a buprenorphine-containing...
2018/0092904 NOVEL METHODS OF USE OF TETRAHYDROBERBERINE (THB)
Tetrahydroberberine (THB), isolated from the Chinese herb "Corydalis ambigua", exhibits a variety of pharmacological effects, although mechanisms of action are...
2018/0092903 METHODS OF TREATING CANCER PATIENTS WITH FARNESYLTRANSFERASE INHIBITORS
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a...
2018/0092902 CCR6 COMPOUNDS
Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6: ##STR00001##
2018/0092901 COMBINATION OF A PD-1 ANTAGONIST AND A VEGF-R/FGFR/RET TYROSINE KINASE INHIBITOR FOR TREATING CANCER
The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a multi-RTK inhibitor, and the use of...
2018/0092900 PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or...
2018/0092899 METHOD OF TREATING ACUTE MIGRAINE WITH CGRP-ACTIVE COMPOUND
A method of alleviating or mitigating at least one symptom of migraine attack by administering to a patient suffering from a migraine attack a therapeutically...
2018/0092898 PROCESSES OF MAKING AND CRYSTALLINE FORMS OF A MDM2 INHIBITOR
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsu- ...
2018/0092897 METHODS AND DEVICES FOR THE TREATMENT OF OCULAR DISEASES IN HUMAN SUBJECTS
Methods and devices are provided for targeted non-surgical administration of a drug formulation to the suprachoroidal space (SCS) of the eye of a human subject...
2018/0092896 MATERIALS AND METHODS FOR DIAGNOSIS, PREVENTION AND/OR TREATMENT OF STRESS DISORDERS AND CONDITIONS ASSOCIATED...
The subject invention concerns materials and methods for treating and/or preventing diseases associated with accumulation of A.beta. peptide in neural tissue....
2018/0092895 METHOD OF TREATMENT OF HEPATITIS C
The present invention relates to pharmaceutical composition of calcium channel blocker for the method of treatment of hepatitis C in humans. The methods of the...
2018/0092894 TREATMENT OF EOSINOPHILIC INFLAMMATORY DISEASE
Provided herein are compositions and methods for the treatment of eosinophilic inflammatory diseases of the mucosal surfaces using proton pump inhibitors. In...
2018/0092893 METHODS OF USING A PHARMACEUTICAL COMPOSITION CONTAINING PIRFENIDONE IN SUSTAINED-RELEASE TABLET FORM
The instant invention relates to a process for the preparation of a pharmaceutical composition in sustained-release tablet form comprising from 600 milligrams...
2018/0092892 Compositions and Methods for Treating Anemia
Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia...
2018/0092891 PREVENTING AMYLOID PLAQUE FORMATION BY TREATING A HUMAN SUBJECT WITH A NITROXIDE
Disclosed herein are embodiments of a method of inhibiting amyloid plaque deposition. In some embodiments, the method comprises: administering to an individual...
2018/0092890 NOOTROPIC COMPOSITIONS FOR IMPROVING MEMORY PERFORMANCE
The invention relates to compositions and methods for improving memory and related functions as alertness, attention, concentration, learning, and language...
2018/0092889 USE OF ATPENIN TO ACTIVATE INNATE IMMUNITY
Provided is a method for inducing innate apolipoprotein B editing catalytic protein (APOBEC) driven C>U RNA deamination of RNA in a cell comprising...
2018/0092888 PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF NEURODEGENERATIVE DISEASES
There is provided a pharmaceutical composition for treatment or prevention of a neurodegenerative disease, comprising an RXR agonist as an active ingredient,...
2018/0092887 COMPOSITIONS OF 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUNDS AND METHODS FOR THEIR USE
Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are...
2018/0092886 METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES
The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or...
2018/0092885 METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES
The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or...
2018/0092884 METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES
The present invention relates to the compound [2-[(5-nitro-1, 3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) ...
2018/0092883 PHOSPHATASE INHIBITORS FOR TREATING OCULAR DISEASES
Disclosed are compounds and pharmaceutical compositions effective for inhibition of HPTP-.beta.. The compounds can provide effective therapy for ocular...
2018/0092882 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MACULAR DEGENERATION
The present invention is directed to topical ophthalmic compositions of a lipophilic compound and an oligomeric or polymeric carrier wherein the compositions...
2018/0092881 Dosage Regimen, Medication Dispensing Package and Uses Thereof for the Treatment of Major Depressive Disorder
This invention provides an oral dosage regimen for the treatment of depression, a pharmaceutically acceptable medication dispensing package containing multiple...
2018/0092880 SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS
3-aza-bicyclo[3.1.0]hexane-6-carboxylic acid amide derivatives which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating...
2018/0092879 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
2018/0092878 COMBINATION OF LIPOIC ACID AND TAURINE AS OSMOPROTECTIVE AGENT
The present invention relates to a combination of lipoic acid and taurine for use as an osmoprotective agent for the prevention and treatment of ailments of...
2018/0092877 TOPICAL ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITION WITH ZILEUTON CREAM FORMULATION
Provided herein is a zileuton cream type topical anti-inflammatory pharmaceutical composition, and more particularly, a zileuton cream type topical...
2018/0092876 Treating or Preventing Nephrogenic Diabetes Insipidus
In certain embodiments, the disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount...
2018/0092875 PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE FOR ADMINISTRATION AT A LOW DAILY DOSE
The present invention relates to pharmaceutical compositions containing dimethyl fumarate (DMF), More specifically, the present invention relates to a...
2018/0092874 IDENTIFICATION AND USE OF VERY LONG CHAIN DICARBOXYLIC ACIDS FOR DISEASE DIAGNOSIS, CHEMOPREVENTION, AND TREATMENT
A method for determining colorectal cancer risk includes obtaining a blood sample of the subject, isolating serum or EDTA plasma from the blood sample,...
2018/0092873 USE OF NITRATED LIPIDS FOR TREATMENT OF SIDE EFFECTS OF TOXIC MEDICAL THERAPIES
Methods of treating the side effects of a toxic medical therapy using nitrated lipids are disclosed herein. In particular, the methods comprise the use of...
2018/0092872 GEL COMPOSITION FOR TREATMENT OF COMMON ACNE COMPRISING A COMBINATION OF BENZOYL PEROZIDE AND ADAPALENE AND/OR...
Dermatological/cosmetic compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including...
2018/0092871 ANTIMICROBIALS AND METHODS OF USE THEREOF
This disclosure provides generally for antimicrobial compositions and methods of use comprising an anthocyanin, an anthocyanidin or metabolites thereof....
2018/0092870 Butyrate Based Skin Formulation
A topical composition for the treatment of inflammatory skin conditions including a butyrate active ingredient and a dermatologically acceptable carrier. The...
2018/0092869 PHARMACEUTICAL QUALITY STRONTIUM L-LACTATE
The present application relates to strontium L-lactate compositions and methods of use. The methods and compositions disclosed herein are particularly useful...
2018/0092868 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND PARKINSON'S DISEASE
The present invention is directed to tablets for oral administration to a subject, comprising a therapeutically effective amount of SYN120 or a ...
2018/0092867 Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4',9'...
The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from ...
2018/0092866 SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR...
In one aspect, the invention relates to substituted N-([1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide analogues, derivatives thereof, and related...
2018/0092865 NOVEL TREATMENTS FOR ATTENTION AND COGNITIVE DISORDERS, AND FOR DEMENTIA ASSOCIATED WITH A NEURODEGENERATIVE...
The present invention provides a method of treating or preventing an attention and/or cognitive disorder in a subject in need thereof, comprising administering...
2018/0092864 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS
Functional analogs of fenfluramine are provided. The subject fenfluramine functional analogs find use in the treatment of a variety of diseases. For example,...
2018/0092863 ANTICOAGULANT COMPOUNDS AND THEIR USE
According to the invention there is provided a compound of formula (I): wherein R.sup.1, R.sup.2, R.sup.3 and n have meanings given in the description, or a...
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