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Patent # Description
2018/0099011 Compositions and Methods for Treating Irritable Bowel Syndrome and Related Disorders
The present disclosure is in the field of pharmaceutical compositions suitable for the treatment of diseases in mammals. The disclosure provides novel...
2018/0099010 Compositions and Methods for Treating Multiple Sclerosis and Related Disorders
The present disclosure is in the field of pharmaceutical compositions suitable for the treatment of diseases in mammals. The disclosure provides novel...
2018/0099009 Bony Tissue Delivery Systems and Methods
A delivery system and method suitable for delivering a fluid to an interior of a bone and for removing fluid including bodily material from the interior of the...
2018/0099008 METHODS OF TISSUE REPAIR AND REGENERATION
The disclosure provides local delivery of a trace element to a site of tissue injury, which triggers the body' inherent tissue repair mechanism. Local delivery...
2018/0099007 Polysaccharide-Polyamine Copolymers For Removal Of Phosphate
Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic...
2018/0099006 USE OF ALGINATE COMPOSITIONS IN PREVENTING OR REDUCING LIVER DAMAGE CAUSED BY A HEPATOTOXIC AGENT
Disclosed herein are compositions, methods and uses utilizing alginate compositions, for treating, preventing and/or reducing liver damage induced by a...
2018/0099005 CHITOSAN COVALENTLY LINKED WITH SMALL MOLECULE INTEGRIN ANTAGONIST FOR TARGETED DELIVERY
The invention relates to the chitosan polymer derivatives of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Y, X.sup.1, X.sup.4,...
2018/0099004 THERAPEUTIC AGENT FOR EYE DISEASE
The present invention provides a single stranded nucleic acid molecule represented by the following formula (I): TABLE-US-00001 (I) (SEQ ID NO: 1) ...
2018/0099003 ANTI-BACTERIAL APPLICATIONS OF POLY-N-ACETYLGLUCOSAMINE NANOFIBERS
Described herein are compositions comprising shortened fibers of poly-N-acetylglucosamine and/or a derivative thereof ("sNAG nanofibers") and anti-bacterial...
2018/0099002 TUMOR-SELECTIVE COMBINATION THERAPY
The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination...
2018/0099001 DIAGNOSTICS AND METHODS FOR TREATMENT OF NON-ALCOHOLIC HEPATIC STEATOSIS AND HEPATIC STEATOHEPATITIS, AND...
The present invention is directed to a System characterization of NASH that combines Modeling and Biomarkers, enabling pharmaceutical compositions and methods...
2018/0099000 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis
The present invention provides a method for the prophylaxis or treatment of systemic lupus erythematosus and/or lupus nephritis in a patient in need thereof,...
2018/0098999 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF
This invention relates to methods and compositions for use improving cell viability, particularly neural cell viability, and more particularly to methods and...
2018/0098998 HETEROCYCLIC AMIDES AS KINASE INHIBITORS
Disclosed are compounds having the formula: ##STR00001## wherein X, Y, Z.sup.1, Z.sup.2, Z.sup.3, Z.sup.4, R.sup.5, R.sup.A, m, A. L, and B are as defined...
2018/0098997 PHARMACEUTICAL DOSES FOR A BROMODOMAIN AND EXTRATERMINAL PROTEIN (BET) INHIBITOR
The invention is a method for treating patients with cancer comprising administering to the patient a safe and effective dose of ...
2018/0098996 MODIFIED RELEASE PREPARATIONS CONTAINING OXCARBAZEPINE AND DERIVATIVES THEREOF
Controlled-release preparations of oxcarbazepine and derivatives thereof for once-a-day administration are disclosed. The inventive compositions comprise...
2018/0098995 Combination Products with Tyrosine Kinase Inhibitors and their Use
The present invention relates to pharmaceutical products comprising a combination of (i) a MET inhibitor and (ii) an EGFR inhibitor, or a pharmaceutically...
2018/0098994 PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2-(1-HYDROXY-ALKYL)-CHROMEN-4-ONE...
The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the...
2018/0098993 USE OF (2R, 6R)-HYDROXYNORKETAMINE, (S)-DEHYDRONORKETAMINE AND OTHER STEREOISOMERIC DEHYDRO AND HYDROXYLATED...
The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro...
2018/0098992 ANTIVIRAL THERAPY
The present invention relates to combinations of compounds comprising HIV integrase inhibitors and other therapeutic agents. Such combinations are useful in...
2018/0098991 COMPOSITION FOR LIPID DISORDER TREATMENT
A pharmaceutical composition for controlling the lipid metabolism or for the treatment or prevention of dislipidemia, dislipoproteinemia, or ...
2018/0098990 HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF
A compound represented by Formula I or pharmaceutically acceptable salt thereof. The present invention relates to a 4-arylamino quinazoline hydroxamic acid...
2018/0098989 FLUOROURACIL GLYCOLATE A NEW COMPOUND IN THE TREATMENT OF WARTS, MOLLUSCUM CONTAGIOSUM: MAGIC WART CREAM
This is a disclosure for a prescription formulation of fluorouracil Glycolate: Magic Wart Cream. Its treatment regimen results in eradication of HP Group 1-6...
2018/0098988 TREATMENT OF AUTOIMMUNE DISEASE
Provided herein are compositions and methods for the treatment of autoimmune diseases, including lupus, uveitis and encephalitis. Said compositions useful for...
2018/0098987 PRMT5 Inhibitors and Uses Thereof
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present...
2018/0098986 ABUSE RESISTANT TRANSMUCOSAL DRUG DELIVERY DEVICE
The present invention relates to a solid pharmaceutical dosage form for abusable drug delivery with reduced illicit abuse potential. The dosage form is...
2018/0098985 METHOD OF TREATING PAIN UTILIZING CONTROLLED RELEASE OXYMORPHONE PHARMACEUTICAL COMPOSITIONS AND INSTRUCTION ON...
The invention pertains to a method of using oxymorphone in the treatment of pain by providing a patient with an oxymorphone dosage form and informing the...
2018/0098984 PHARMACEUTICAL COMPOSITIONS COMPRISING DEXTROMETHORPHAN AND QUINIDINE FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in...
2018/0098983 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
Chemical entities that modulate PI3 kinase activity, pharmaceutical compositions containing the chemical entities, and methods of using these chemical entities...
2018/0098982 ORAL PHARMACEUTICAL COMPOSITION OF METHYLERGONOVINE AND METHODS OF USE THEREOF
A solid pharmaceutical oral composition for once daily administration is provided. The composition includes from about 0.5 mg to about 0.8 mg in total of...
2018/0098981 THERAPEUTICAL COMPOSITION CONTAINING APOMORPHINE AS ACTIVE INGREDIENT
A pharmaceutical composition contains apomorphine as the active pharmaceutical ingredient, a water-miscible co-solvent, an antioxidant, and water. The solution...
2018/0098980 METHODS AND OPHTHALMIC DEVICES USED IN THE TREATMENT OF OCULAR ALLERGIES
Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.
2018/0098979 TRANSDERMAL ADMINISTRATION OF FENTANYL AND ANALOGS THEREOF
A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a...
2018/0098978 AMLODIPINE FORMULATIONS
Provided herein are stable amlodipine oral liquid formulations. Also provided herein are methods of using amlodipine oral liquid formulations for the treatment...
2018/0098977 SCALABLE MICROPARTICULATE FORMULATIONS CONTAINING POLYMORPHIC NIMODIPINE FORM 2 PREPARED BY A SOLVENT...
The described invention provides stable sustained release particulate formulations of polymorphic Form II of nimodipine and processes for their manufacture...
2018/0098976 MAGNESIUM PICOLINATE COMPOSITIONS AND METHODS OF USE
The present application relates to magnesium picolinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful...
2018/0098975 METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OX- ...
Methods of treating, preventing or managing cancer, including certain leukemias are disclosed. The methods encompass the administration of enantiomerically...
2018/0098974 METHODS OF TREATING DEVELOPMENTAL DISORDERS WITH GABOXADOL
Methods of treating developmental disorders such as Angelman syndrome, Fragile X syndrome, Fragile X-associated tremor/ataxia syndrome (FXTAS), Autistic...
2018/0098973 PRAMIPEXOLE TRANSDERMAL DELIVERY SYSTEM AND USES THEREOF
A pramipexole transdermal patch for treatment of neurological disorders including Parkinson's disease that may be administered on a daily basis. The...
2018/0098972 TREATMENT OF INFECTIOUS DISEASES
Disclosed herein are methods for treating or preventing a disease comprising administering a pharmaceutical composition comprising a therapeutically-effective...
2018/0098971 Transplantation Adjuvant in Cell Therapy Using Neural Progenitor Cells
The present invention provides a transplantation adjuvant for neural progenitor cells containing valproic acid and/or zonisamide as an active ingredient.
2018/0098970 USE OF ISOINDOLES FOR THE TREATMENT OF NEUROBEHAVIORAL DISORDERS
The present invention generally relates to the use of drugs for the treatment of a neurobehavioral disorder associated with dysfunction of the trimonoamine...
2018/0098969 HODGKIN LYMPHOMA THERAPY
There is provided a method of treating Hodgkin lymphoma in a patient in need thereof comprising administering to said patient an effective amount of a compound...
2018/0098968 ANESTHETIC COMPOUNDS AND RELATED METHODS OF USE
Provided herein are compounds according to formula (I): ##STR00001## Provided herein is also a pharmaceutical composition comprising a compound according to...
2018/0098967 CLONIDINE AND/OR CLONIDINE DERIVATIVES FOR USE IN THE PREVENTION OF SKIN INJURY RESULTING FROM RADIOTHERAPY
The present invention pertains to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and Clonidine and/or Clonidine derivatives as a...
2018/0098966 CLONIDINE AND/OR CLONIDINE DERIVATIVES FOR USE IN THE PREVENTION AND/OR TREATMENT OF ADVERSE SIDE EFFECTS OF...
The present invention pertains to specific clonidine and/or clonidine derivatives for use in the prevention and/or treatment of adverse side effects of...
2018/0098965 LOCALLY BIOAVAILABLE DRUGS
Drugs have been designed and developed with a structural motif allowing local bioavailability in the target organ but that are not broadly distributed at a...
2018/0098964 GENOTYPE SPECIFIC METHODS FOR TREATING HUMAN SUBJECTS USING 4-METHYLPYRAZOLE
Provided herein are methods of administering 4-methylpyrazole (4-MP), or physiologically acceptable salts thereof, to subjects of geneic subpopulations...
2018/0098963 LASOFOXIFENE TREATMENT OF BREAST CANCER
The disclosure provides methods for treating estrogen receptor positive (ER.sup.+) cancer in women with an effective amount of lasofoxifene, a pharmaceutically...
2018/0098962 FORMULATIONS OF WATER-SOLUBLE DERIVATIVES OF VITAMIN E AND SOFT GEL COMPOSITIONS, CONCENTRATES AND POWDERS...
Provided herein are compositions that contain water-soluble vitamin E derivative mixtures (compositions), such as tocopheryl polyethylene glycol succinate...
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