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Patent # Description
2018/0104248 THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF IN A SYNERGISTIC COMBINATION WITH CAFFEINE
A human dietary supplement comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theacrine-containing...
2018/0104247 PYRROLOPYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER
Compounds of Formula I: ##STR00001## wherein: one of X and X' is N and the other of X and X' is C, are described, along with compositions containing the same and...
2018/0104246 THERAPEUTIC COMPOUNDS AND USES THEREOF
Described herein are compounds of Formula (I)-(III), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are...
2018/0104245 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES
The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-I), and their use for treatment and...
2018/0104244 COMPOSITIONS AND METHODS FOR TREATMENT OF FRAGILE X SYNDROME
Disclosed are methods of alleviating or preventing one or more symptoms associated with fragile X syndrome in an individual in need thereof via administration...
2018/0104243 Tricyclic Amino Containing Compounds for Treatment or Prevention of Symptoms Associated with Endocrine Dysfunction
The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those...
2018/0104242 4-(2-AMINO-TETRAHYDRONAPHTHALENYL)PYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL...
The present invention relates to a 4-(2-amino-tetrahydronaphthaleneyl)pyrimidine derivative, a preparation method thereof, and a pharmaceutical composition for...
2018/0104241 CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY
A very stable, selective and nrenally safe sodium channel blocker represented by the formula: ##STR00001## The invention also includes a variety of compositions,...
2018/0104240 AMELIORATION OF RADIATION-INDUCED COGNITIVE DYSFUNCTION
Treatment with 2-amino substituted nicotinamides ameliorates the cognitive dysfunction resulting from radiation of the brain.
2018/0104239 Dry Powder Formulation of Azole Derivative for Inhalation
A spray dried-powder composition for inhalation comprising particles (X) containing (a) between 5 and 50% by weight of at least one azole derivative in...
2018/0104238 Method And Composition For Treating Rhinitis
There is provided pharmaceutical compositions for the treatment of rhinitis by, for example, nasal or ocular administration comprising zwitterionic cetirizine,...
2018/0104237 Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient...
2018/0104236 METHODS OF TREATMENT COMPRISING ADMINISTERING A HIGH DAILY DOSE OF OXYCODONE AND NALOXONE IN A 2:1 WEIGHT RATIO
The present invention relates to methods of treatment comprising, inter alia, administering a high daily dose of oxycodone, such as a daily dose of at least 90...
2018/0104235 NEW ABUSE-RESISTANT PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF OPIOID DEPENDENCE
There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of...
2018/0104234 COMBINATION THERAPY FOR CANCER
The present invention provides a method of treating squamous histology cancers and PI3K pathway activated large cell lung and colorectal cancers in a patient...
2018/0104233 METHODS OF TREATMENT AND PHARMACEUTICAL COMPOSITIONS USING BCN057 OR BCN512
The present disclosure is directed to method of treatment for treating or ameliorating various conditions pertaining such as bone marrow recovery (or blood...
2018/0104232 METHODS FOR DETERMINING PROGNOSIS FOR BREAST CANCER PATIENTS
Described herein are methods for treating breast cancer and for providing a prognosis for metastatic-free survival of breast cancer patients. Aspects relate to...
2018/0104231 BENZALKONIUM CHLORIDE FREE OPHTHALMIC COMPOSITION CONTAINING (+)-(S)-4-[4-CHLOROPHENYL) (2-PYRIDYL) METHOXY]...
The present invention relates to pharmaceutical composition(s) containing active ingredient and inactive ingredients without preservative(s). The ...
2018/0104230 PHARMACEUTICAL COMPOSITION COMPRISING GLUTARIMIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF EOSINOPHILIC...
The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their...
2018/0104229 Method of Treating Skin Disorders
In one aspect, a method of treating a disorder associated with chronic inflammation includes administering to an individual in need thereof a therapeutically...
2018/0104228 METHODS AND COMPOSITIONS FOR TREATING NON-ERK MAPK PATHWAY INHIBITOR-RESISTANT CANCERS
The present invention provides, inter alia, methods, pharmaceutical compositions, and kits for treating or ameliorating the effects of a cancer in a subject,...
2018/0104227 NAIL LACQUER COMPOSITION CONTAINING CICLOPIROX
The present invention relates to a nail lacquer composition containing at least one antifungal agent as a pharmacologically active ingredient. The present...
2018/0104226 ANTI-MALARIAL AGENT
The invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the...
2018/0104225 BOWEL CLEANSING COMPOSITION
A bowel cleansing composition includes as a first cleansing ingredient, a specific sugar alcohol such as xylitol, sorbitol, etc., as a second cleansing...
2018/0104223 TREATMENT OF PAIN
(3S)-Tetrahydrofuran-3-yl(4S)-4-isopropyl-1,4,6,7-tetrahydro-5H-imidazo[4- ,5-c]-pyridine-5-carboxylate, and salts thereof for use in the treatment of pain.
2018/0104222 TREATING ATHEROSCLEROSIS BY REMOVING SENESCENT FOAM CELL MACROPHAGES FROM ATHEROSCLEROTIC PLAQUES
Foamy macrophages with senescence markers accumulate in the subendothelial space at the onset of atherosclerosis where they drive pathology by increasing...
2018/0104221 CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
A compound exerts a strong analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. A cyclic amine derivative represented...
2018/0104220 IMIDAZOLE COMPOUND
Disclosed is an imidazole compound, in particular, the compound as shown in formula (I) and a pharmaceutically acceptable salt or tautomer thereof are...
2018/0104219 METHOD OF RESTORING ANALGESIC EFFICACY OF ALPHA2-ADRENOCEPTOR AGONISTS IN NEUROPATHIC PAIN TREATMENT
Provided are a pharmaceutical composition including: an alpha 2 (.alpha.2)-adrenoceptor agonist; a regulator of G-protein signaling (RGS) inhibitor, an...
2018/0104218 RESUSCITATION COMPOSITION AND METHODS OF MAKING AND USING
A resuscitation composition is described herein, as are methods of making and using such a composition.
2018/0104217 Ropinirole-Containing Adhesive Patch
Provided is an adhesive patch containing ropinirole serving as a therapeutic drug for Parkinson's disease, with the ropinirole used being free ropinirole...
2018/0104216 PHARMACEUTICAL COMPOSITION CONTAINING SILIBININ AND PUERARIA ROOT EXTRACT
Disclosed are a pharmaceutical composition for treating non-alcoholic fatty liver and a method for preparing same. The composition is prepared from the...
2018/0104215 PHARMACEUTICAL COMPOSITION CONTAINING SILYBIN AND L-CARNITINE
A pharmaceutical composition for treating non-alcoholic fatty liver diseases. The pharmaceutical composition is prepared from 8.75-60 parts by weight of...
2018/0104214 VAPORIZING DEVICES AND METHODS FOR DELIVERING A COMPOUND USING THE SAME
A method of treating disorders in a human or animal subject may include heating a material containing a compound to a first temperature to form a heated volume...
2018/0104213 CANNABIS BASED COMPOSITIONS AND METHODS OF TREATING HYPERTENSION
The invention relates to a Cannabis-based pharmaceutical composition for the treatment of hypertensive disorders by submucosal delivery comprising a...
2018/0104212 Stabilized Cabazitaxel Formulations
Disclosed herein are improved formulations for the cabazitaxel. The formulations exhibit increased storage stability relative to other formulations, and are...
2018/0104211 HYPOESTOXIDE, DERIVATIVES, RELATED COMPOUNDS, AND AGONISTS THEREOF FOR TREATMENT OR PREVENTION OF...
New uses of hypoestoxide, its derivatives and related compounds for treatment and prevention of neurodegenerative diseases (e.g. Parkinsons disease, Alzheimers...
2018/0104210 DERMATOPHYTOSIS PROPHYLAXIS AND TREATMENT
A composition and method for the prophylaxis and treatment of topical fungal infections is provided. Generally, the composition includes an HMG-CoA reductase...
2018/0104209 PREVENTION OF PSYCHOTIC DISORDERS AND/OR TREATMENT OF PSYCHOTIC SYMPTOMS
The present invention relates to methods of preventing a psychotic disorder in a subject in need of intervention including administering to the subject a...
2018/0104208 PHARMACEUTICAL COMPOSITIONS COMPRISING DGLA AND USE OF SAME
The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions...
2018/0104207 COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF USING THE SAME
The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
2018/0104206 SOAP COMPOSITIONS AND METHODS
Natural soap compositions and methods of manufacturing the same having anti-microbial properties for treating and preventing diaper rash and other microbial...
2018/0104205 MUCOSAL IMMUNOSTIMULATOR
The present invention provides a mucosal immunostimulator comprising, as an active ingredient, at least one selected from the group consisting of saturated...
2018/0104204 High-Stability Packaged Solutions of T4 Thyroid Hormone
The invention relates to highly stable alcohol-free, water-glycerol solutions of T4 thyroid hormone, with a reduced amount of T3 impurity, packaged via...
2018/0104203 ADMINISTRATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID FOR THE TREATMENT OF DERMATOLOGICAL...
Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by...
2018/0104202 Methods of Treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic...
Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a...
2018/0104201 USE OF STRUCTURALLY ENHANCED FATTY ACIDS CONTAINING SULPHUR FOR PREVENTING AND OR TREATING NON ALCOHOLIC...
The present disclosure relates to a method of preventing and/or treating non-alcoholic steatohepatitis in a subject in need thereof, comprising administering...
2018/0104200 TOPICAL FORMULATIONS AND TREATMENTS
The present invention provides topical dosages and formulations of lidocaine and pharmaceutically acceptable salts thereof, which are efficacious, chemically...
2018/0104199 METHOD OF USING NICLOSAMIDE DERIVATIVES
Niclosamide derivatives are provided in the present invention. More particularly, the methods of using niclosamide derivatives for the manufacture of...
2018/0104198 Pharmaceutical Composition, Methods for Treating and Uses Thereof
The invention relates to a pharmaceutical combination comprising an SSAO/VAP-1 inhibitor according to the formula (I) ##STR00001## wherein R1 to R6, and X are as...
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