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Patent # Description
2018/0112040 THERMOPLASTIC COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE THEREOF
A thermoplastic composition comprises, based on the total weight of the thermoplastic composition, 3 to 20 wt. % of an impact modifier composition comprising a...
2018/0112038 POLY(BETA-AMINO ESTER)-CO-POLYETHYLENE GLYCOL (PEG-PBAE-PEG) POLYMERS FOR GENE AND DRUG DELIVERY
Polyethylene glycol (PEG)-b-poly(.beta.-amino ester) (PBAE) co-polymers (PEG-PBAE) and blends of PEG-PBAEs and PBAEs and their use for delivering drugs, genes,...
2018/0112037 POLYMERIC AMINE SYNERGIST
A polymeric amine synergist is disclosed herein. An example of the polymeric amine synergist includes an aniline moiety, a polyethylene glycol chain, and an...
2018/0112036 NOVEL FLUORINATED SURFACTANTS
The present disclosure provides amphiphilic fluorinated surfactant molecules for lowering the surface tension of aqueous, hydrocarbon, or solid phases in the...
2018/0112035 POLYMER BLENDS COMPRISING POLYCARBONATE AND POLYMETHYL METHACRYLATE
The disclosure concerns a polymer derived from melt extrusion of (i) 80 to 95 wt % polycarbonate; said polycarbonate having and endcap level of 45% to 80% and...
2018/0112034 SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION
Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general...
2018/0112033 POLYESTER NANOGEL CORE STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS
Amphiphilic star polymers were prepared having superior loading properties for delivery of hydrophobic biologically active materials intended for use in...
2018/0112032 CURED FILM FORMATION COMPOSITION, ORIENTATION MATERIAL, AND RETARDATION MATERIAL
A cured-film formation composition that forms a cured film exhibiting excellent liquid-crystal orientation properties and excellent light transmission...
2018/0112031 A Process for the Preparation of Insulation Systems for Electrical Engineering, the Articles Obtained Therefrom...
A process for the preparation of insulation systems for electrical engineering by automatic pressure gelation (APG), wherein a multiple component thermosetting...
2018/0112030 CYCLIC CARBONATES
Compounds of the formula ##STR00001## in which R.sup.1 is an organic radical having a (meth)acryloyl group and R.sup.2, R.sup.3, and R.sup.4 independently of one...
2018/0112029 RESIN COMPOSITION, RESIN SHEET, RESIN CURED PRODUCT, AND RESIN SUBSTRATE
A resin composition includes an epoxy compound, a triphenylbenzene compound, an inorganic particle including a magnesium oxide (MgO) or the like, and...
2018/0112028 ABSORBENT POLYMERIC MATERIAL, METHOD FOR PRODUCING SAME AND USES THEREOF
The present disclosure relates to a polymeric material having dilating properties and production of the respective material, such that it is incorporated into...
2018/0112027 Low-Viscosity Phosphate Polyols
A novel phosphate polyol formulation is described, comprising a polyester polyol, a flame retardant comprising a phosphate polyol, a blowing agent, a catalyst,...
2018/0112026 SILANE GROUPS CONTAINING POLYISOCYANATES BASED ON 1,5-DIISOCYANATOPENTANE
The invention relates to modified polyisocyanates, obtained by reacting at least one polyisocyanate (A) based on 1,5-diisocyanatopentane with at least one...
2018/0112025 URETHANE-MODIFIED PREPOLYMERS CONTAINING PENDENT ALKYL GROUPS, COMPOSITIONS AND USES THEREOF
Adducts and prepolymers comprising pendent alkyl groups are disclosed. Polythiol adducts prepared by reacting a polythiol with a ketone and urethane-extended...
2018/0112024 RESIN FOR INK AND INK
A resin for ink is obtained by reaction of a lignin, phenols, aldehydes, a rosin-based resin, and polyhydric alcohol.
2018/0112023 ACRYLIC BLOCK COPOLYMER, RESIN COMPOSITION AND SHAPED ARTICLE INCLUDING THE SAME, AND OPTICAL COMPONENT
The invention provides an acrylic block copolymer which has excellent transparency, profile extrusion properties and surface smoothness of shaped articles, and...
2018/0112022 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL
Provided are a polymerizable composition in which precipitation or the like of crystals does not occur and which has high storage stability; and a...
2018/0112021 Controlled Architecture Polymerization with Photoinitiator Groups in Backbone
Acrylic copolymers that include the controlled placement of particular functional groups within the polymer structure are provided. The copolymers comprise a...
2018/0112020 ETHYLENE COPOLYMERISATES HAVING IMPROVED LOW-TEMPERATURE PROPERTIES AND GOOD OIL RESISTANCE, VULCANIZABLE...
The present invention relates to copolymers of ethylene, vinyl esters of an akyl carboxylic acid and other specific unsaturated carboxylic esters which have...
2018/0112019 LIGHT EMITTER DEVICES AND COMPONENTS WITH IMPROVED CHEMICAL RESISTANCE AND RELATED METHODS
Disclosed are LEDs and LED packages, and methods of making them, having improved resistance to infiltration by chemical entities comprising providing a coating...
2018/0112018 HOSE WITH TUNABLE FLEXIBILITY USING CYCLIZABLE, PHOTOCHROMIC MOLECULES
Embodiments of the disclosure generally provide compositions and methods related to articles that display reversible photoresponsive behavior.
2018/0112017 Ethylene-Based Polymers with Low Hexane Extractables
Ethylene-based polymers comprising the following properties: (A) a density from 0.9190 g/cc to 0.9240 g/cc; (B) a hexane extractable level that is less than or...
2018/0112016 METHOD FOR PRODUCING HALOGENATED ISOOLEFIN-BASED POLYMER
A method for producing a halogenated isoolefin-based polymer includes irradiating an isoolefin-based polymer including alkylstyrene with light in presence of a...
2018/0112015 POLYMERIZATION INITIATOR, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHODS FOR PREPARING THEM
The present invention relates to a polymerization initiator represented by Formula 1, a modified conjugated diene-based polymer, methods for preparing them, a...
2018/0112014 STABILIZED COMPOSITION FOR COMBINED ODOR CONTROL AND ENHANCED DEWATERING
A composition comprising a compound mixture dissolved in water, the compound mixture comprising at least one chlorite salt at least one cyclodextrin; and at...
2018/0112013 METHOD FOR PREPARING LIQUID MEDIUM COMPOSITION, AND PREPARATION DEVICE AND KIT THEREFOR
The present invention provides a method capable of easily mixing any liquid containing a linking substance such as a divalent metal cation and the like with a...
2018/0112012 PROCESS FOR THE OXIDATION OF STARCH-BASED MATERIALS
A process for the oxidation of powder materials containing starch, which comprises the successive steps of mixing a powder material comprising starch with an...
2018/0112011 T CELL RETARGETING HETERO-DIMERIC IMMUNOGLOBULINS
The present invention describes novel hetero-dimeric immunoglobulins or fragments thereof which bind to CD3 and a disease associated antigen. These...
2018/0112010 METHODS FOR PHRASING EPIGENETIC MODIFICATIONS OF GENOMES
Provided herein are methods and compositions for analyzing epigenetic modifications of genomes. The methods and compositions are suited for complete epigenome...
2018/0112009 ANTIBODIES CAPABLE OF BINDING TO THE COAGULATION FACTOR XIA AND USES THEREOF
The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof,...
2018/0112008 ANTI-MUC16 ANTIBODIES AND USES THEREOF
Provided herein are compositions, methods, and uses involving antibodies that immunospecifically bind glycosylated forms of MUC16, a tethered mucin protein....
2018/0112007 HUMANIZED ANTI-MUC1* ANTIBODIES
The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
2018/0112006 AGENTS, SYSTEMS AND METHODS FOR TREATING CANCER
Compositions and methods are provided comprising soluble TRAIL polypeptide agents and cells engineered to express such agents for the treatment of multifocal...
2018/0112005 POLYNUCLEOTIDES ENCODING ANTI-NOTCH1 NRR ANTIBODY POLYPEPTIDES
The invention provides anti-Notch1 NRR antibodies, and compositions comprising and methods of using these antibodies.
2018/0112004 ENGINEERED SITE-SPECIFIC ANTIBODIES AND METHODS OF USE
Provided are novel antibody drug conjugates (ADCs), and methods of using such ADCs to treat proliferative disorders.
2018/0112003 CAR T-CELL THERAPY DIRECTED TO LHR FOR THE TREATMENT OF SOLID TUMORS
Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and...
2018/0112002 MODULATORS OF ROR1-ROR2 BINDING
Provided herein are, inter alia, methods of identifying agents that are capable inhibiting the binding (e.g., coupling) between a ROR1 protein and a ROR2...
2018/0112001 Anti-MUC16 Antibodies, Antibody-Drug Conjugates, and Bispecific Antigen-Binding Molecules that Bind MUC16 and...
Mucin 16 (MUC16) is highly expressed in ovarian cancer and expression on cancer cells is shown to protect tumor cells from the immune system. The present...
2018/0112000 HUMANIZED ANTIBODY OR FRAGMENT THEREOF SPECIFIC FOR CD3
The present invention provides a humanized antibody or fragment thereof specific for the antigen CD3, wherein said antibody or fragment thereof comprises a...
2018/0111999 Reducing Systemic Regulatory T Cell Levels or Activity for Treatment of Disease and Injury of the CNS
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a...
2018/0111998 Reducing Systemic Regulatory T Cell Levels or Activity for Treatment of Alzheimer's Disease
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a...
2018/0111997 Reducing Systemic Regulatory T Cell Levels or Activity for Treatment of Alzheimer's Disease
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a...
2018/0111996 ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1
Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variable region sequences are disclosed. A method of increasing the activity (or reducing...
2018/0111995 ANTI-PD1 ANTIBODIES AND THEIR USE AS THERAPEUTICS AND DIAGNOSTICS
Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in...
2018/0111994 LINGO-2 ANTAGONISTS FOR TREATMENT OF CONDITIONS INVOLVING MOTOR NEURONS
The invention provides methods of treating diseases, disorders or injuries involving motor neuron survival and axonal growth, including amylotrophic lateral...
2018/0111993 NUCLEIC ACID CONSTRUCT FOR EXPRESSING MORE THAN ONE CHIMERIC ANTIGEN RECEPTOR
The present invention provides a nucleic acid construct comprising the following structure: A-X-B in which X is a nucleic acid sequence which encodes a...
2018/0111992 DUAL SPECIFIC ANTI-CD22-ANTI-CD19 CHIMERIC ANTIGEN RECEPTORS
The invention provides dual specific chimeric antigen receptors (CARs) having antigenic specificity for CD19 and CD22. Nucleic acids, recombinant expression...
2018/0111991 MODULATORS OF ACTIVIN AND METHODS FOR MODULATING IMMUNE RESPONSES AND T FOLLICULAR HELPER CELLS
The invention provides methods and uses for stimulating, inducing, increasing or enhancing Tfh (follicular helper) cell differentiation, germinal center B cell...
2018/0111990 NEW METHODS FOR EPITOPE SELECTION
The present invention relates to certain new methods to select epitopes for antibodies. The present invention also provides a method of generating an antibody...
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