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Patent # Description
2018/0119237 DIRECT REDUCTION PROCESS AND SHAFT FURNACE UTILIZING AN EXTENDED FLOW DIVERTER CONE
A shaft furnace for producing metallic direct reduced iron (DRI) from iron-containing pellets or lumps and reducing gas disposed therein, including: a...
2018/0119236 DIRECT REDUCTION WITH COAL GASIFICATION AND COKE OVEN GAS
A method and apparatus for producing direct reduced iron (DRI), including: generating a reducing gas in a coal gasifier using coal, oxygen, steam, and a first...
2018/0119234 METHOD FOR IDENTIFYING VARIETY OF HOP
The present invention relates to a method for identifying the variety of a hop by using an identification marker comprising at least one single nucleotide...
2018/0119230 SYSTEMS AND METHODS FOR ANALYZING NUCLEIC ACID
Increased sensitivity and specificity of characterizing patient-specific variations as mutations that are indicative of a cancer or other disease by...
2018/0119228 POINT MUTATIONS IN TRK INHIBITOR-RESISTANT CANCER AND METHODS RELATING TO THE SAME
Provided herein are methods of treating a subject having a cancer, methods of selecting a treatment for a subject having a cancer, methods of selecting a...
2018/0119227 NOVEL RISK BIOMARKERS FOR LUNG CANCER
Methods and kits for determining a risk of a subject, or subjects for developing lung cancer is disclosed. The method comprises determining a level of...
2018/0119226 Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids
Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific...
2018/0119225 DETECTING 5-HYDROXYMETHYLATED CYTOSINE
Provided herein are methods and kits for detecting 5-hydroxymethylated cytosine.
2018/0119224 IDENTIFICATION OF GENE ASSOCIATED WITH READING DISABILITY AND USES THEREFOR
The present invention relates to identification of a human gene, DCDC2 (MIM: 605755), associated with susceptibility for developing reading disability (RD),...
2018/0119220 PARTICULATE DISTRIBUTED SENSING ELEMENTS
The present invention relates to core-shell particles comprising encapsulated nucleic acids--a sensing sequence and a control sequence; the invention further...
2018/0119219 AUGMENTING IN SITU NUCLEIC ACID SEQUENCING OF EXPANDED BIOLOGICAL SAMPLES WITH IN VITRO SEQUENCE INFORMATION
The invention provides in situ nucleic acid sequencing to be conducted in biological specimens that have been physically expanded. The invention leverages the...
2018/0119218 Spatial Molecular Analysis of Tissue
Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with...
2018/0119214 COMPOSITIONS AND METHODS FOR TARGET NUCLEIC ACID MOLECULE ENRICHMENT
The present disclosure relates to methods of detecting mutations in a target nucleic acid molecule by amplifying a target sequence to contain adaptor sequences...
2018/0119210 FETAL HAPLOTYPE IDENTIFICATION
Methods and kits for prenatal genetic testing and particularly for identifying and/or analyzing fetal haplotype with a high degree of confidence are provided.
2018/0119208 On-Slide Staining by Primer Extension
A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to...
2018/0119207 METHODS AND KITS FOR THE DETECTION OF DNA
The present invention is related to methods and kits for the detection of deoxyribonucleic acid (DNA), in particular pathogenic microbial DNA, which provide...
2018/0119205 MACROMOLECULE DELIVERY TO NANOWELLS
Provided herein is technology relating to depositing and/or placing a macromolecule at a desired site for an assay and particularly, but not exclusively, to...
2018/0119204 SYSTEMS AND METHODS FOR THERMAL ACTUATION OF MICROFLUIDIC DEVICES
A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N...
2018/0119203 PHYSICAL LINKAGE PRESERVATION IN DNA STORAGE
Disclosed herein are compositions, systems, kits and methods related to preserving physical linkage information of isolated DNA subject to DNA damage, and...
2018/0119200 COELENTERAZINE ANALOGUES TETHERED TO ENERGY ACCEPTORS
Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection...
2018/0119199 DEVICE FOR ONLINE MEASUREMENT OF NEUROTRANSMITTERS USING ENZYMATIC REACTORS
The invention relates to a device and a method for measuring neurotransmitters in the brain dialysate of mammals using enzymatic reactors specific to a certain...
2018/0119198 Methods, Compositions and Kits for High Throughput Kinase Activity Screening Using Mass Spectrometry and Stable...
A mass-spectrometry-based method and substrates are provided herein for large scale kinome activity profiling directly from crude lysates using 90 chemically...
2018/0119197 STABILIZED TEST STRIP FOR THE DETECTION OF HYDROGEN PEROXIDE
A colorimetric dry-reagent test strip for direct detection of the presence of hydrogen peroxide in strongly acidic solutions without the necessity of a pH...
2018/0119196 Chemoenzymatic Synthesis of Trehalose Analogs
The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues.
2018/0119194 METALLOPROTEIN COMPOSITIONS
The present invention relates to compositions comprising: a polypeptide, wherein at least a portion of the polypeptide has a coiled coil structure; and a...
2018/0119193 EXPRESSION OF MODIFIED GLYCOPROTEINS AND GLYCOPEPTIDES
The present invention provides recombinant cells that contain a modification causing altered expression or function of at least one mannosyl transferase...
2018/0119192 EARLY POST-TRANSFECTION ISOLATION OF CELLS (EPIC) FOR BIOLOGICS PRODUCTION
Provided herein are methods for selecting a population of cells expressing a target polypeptide. In some aspects, the disclosure provides methods for sorting...
2018/0119190 MEDIUM FOR PRODUCING GLUCOSAMINE AND ITS APPLICATION
The invention relates to a medium for producing glucosamine, including 25-500 g/L molasses, 0.01-100 g/L soybean hydrolysate or 0.25-100 g/L corn steep liquor,...
2018/0119189 PROCESS FOR THE HYDROLYSIS OF BIOMASS
The present invention is directed to a novel and advantageous process for the hydrolysis of biomass which enables a thorough hydrolyzation also of recalcitrant...
2018/0119187 METHODS FOR DEGRADING OR CONVERTING CELLULOSIC MATERIAL
The present invention relates to methods for degrading or converting a cellulosic material, comprising: treating the cellulosic material with an enzyme...
2018/0119177 PROCESS FOR THE MANUFACTURE OF BUTANOL OR ACETONE
A process for the manufacture of butanol, acetone and other renewable chemicals utilizes one or more of by-products of the manufacture of malt whisky, such as...
2018/0119176 Heterologous Pathway to Produce Terpenes
Cells comprising a heterologous metabolic pathway are configured to produce a terpene product containing non-multiples of five carbon, particularly wherein the...
2018/0119171 REPLICATIVE VACCINIA VIRUS VECTOR HIV VACCINE
Provided is a recombinant replicative vaccinia virus, the virus comprising a polynucleotide encoding HSV-TK and HIV antigens. Also provided is a live vector...
2018/0119170 POLYPURINE TRACT MODIFIED RETROVIRAL VECTORS
An integration-defective retroviral vector transfer cassette lacking a functional polypurine tract (PPT) is provided. Also provided are isolated nucleic acids...
2018/0119168 NEGATIVE REGULATOR OF PLANT IMMUNITY AGAINST NEMATODES
The present invention provides methods of enhancing immunity to root knot nematodes in plants. The methods comprise introducing mutations into a G-LecRK-VI.13...
2018/0119167 Genes Encoding Lob Domain Protein 16 And Uses For Plant Improvement
Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such...
2018/0119165 INCREASING PLANT GROWTH AND YIELD BY USING AN ERF TRANSCRIPTION FACTOR SEQUENCE
Compositions and methods for improving plant growth are provided herein. Polynucleotides encoding ERF transcription factor proteins, polypeptides encompassing...
2018/0119162 METHODS AND COMPOSITIONS FOR ACCELERATED TRAIT INTROGRESSION
Compositions and methods are provided for the use of pollen-inhibitor genes and/or color marker genes in accelerated trait introgression. Compositions and...
2018/0119158 Modified CPMV Enhancer Elements
An expression enhancer comprising, in series, a CPMV 5'UTR nucleotide sequence comprising nucleotides 1-160 of SEQ ID NO:1, or comprising a nucleotide sequence...
2018/0119154 TRANSLATION ENHANCER FOR USE IN CELL-FREE PROTEIN SYNTHESIS SYSTEM AND USE THEREOF
This specification provides a translation enhancer that makes it possible to obtain translation template mRNA efficiently in a cell-free protein synthesis...
2018/0119153 ANDROGEN RECEPTOR VARIANT INHIBITORS AND METHODS OF USING
This document relates to materials and methods for treating cancer (e.g., prostate cancer). For example, methods for using one or more androgen receptor...
2018/0119152 ANTISENSE COMPOUNDS TARGETING GENES ASSOCIATED WITH CYSTIC FIBROSIS
The present disclosure relates generally to compounds comprising oligonucleotides complementary to a cystic fibrosis transmembrane conductance regulator (CFTR)...
2018/0119151 SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING DELIVERY FUNCTION AND GENE EXPRESSION REGULATING ABILITY
The present invention provides a single-stranded nucleic acid molecule having a delivery function and capable of inhibiting expression of a target gene. The...
2018/0119145 COMPOUNDS AND METHODS FOR REDUCING TAU EXPRESSION
Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of Tau mRNA in a cell or animal, and in certain instances...
2018/0119142 COMPOSITIONS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT
Disclosed herein are compositions and methods for modulating expression of C9ORF72 antisense transcript in a cell or animal with C9ORF72 antisense transcript...
2018/0119140 Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene Regulation
Provided herein are methods for inducing CRISPR/Cas-based gene regulation (e.g., genome editing or gene expression) of a target nucleic acid (e.g., target DNA...
2018/0119139 STRUCTURED SUBSTRATES FOR IMPROVING DETECTION OF LIGHT EMISSIONS AND METHODS RELATING TO THE SAME
A structured substrate (100) including a substrate body (102) having an active side (104). The substrate body (102) includes reaction cavities or sites (106)...
2018/0119137 INTEGRATED SYSTEMS AND METHODS FOR AUTOMATED PROCESSING AND ANALYSIS OF BIOLOGICAL SAMPLES, CLINICAL...
The present disclosure provides a method for identifying a genomic aberration in one or more biological samples of a subject. The biological samples may be...
2018/0119136 METHODS FOR IDENTIFYING TARGETS FOR ANTIMICROBIAL AND ANTIPROLIFERATIVE COMPOUNDS AND COMPOSITIONS THEREFROM
The invention is directed to methods for identifying targets for antimicrobial and antiproliferative compounds as well as methods for identifying novel...
2018/0119134 METHOD FOR SCREENING FOR PEPTIDE SEQUENCES THAT STIMULATE BACTERIAL GROWTH
Compositions and methods for isolating biologically active polypeptides (e.g., bacterial pro-growth polypeptides) are provided. In some aspects, bacterial cell...
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