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Patent # Description
2018/0133248 THERAPEUTIC OZONE AGENT AND TREATMENT
The use of a medical therapeutic ozone agent in vivo to treat a variety of disorders including, but not limited to hypoxic conditions, autoimmune disease,...
2018/0133247 NOVEL DIETARY SUPPLEMENTS
Compositions and methods for improving nitric oxide levels in a subject, comprising administering to a subject, a composition comprising dietary nitrate...
2018/0133246 INHALATION OF NITRIC OXIDE FOR TREATING RESPIRATORY DISEASES
A method of treating a human subject which is effected by intermittent inhalation of gaseous nitric oxide at a concentration of at least 160 ppm is disclosed....
2018/0133245 Impact of electrolytes on tumors and various diseases
I am filing 8 claims, 7 of them are based on the impact received from electrolytes. At the moment I feel that this is a gray area with heavy regulations which...
2018/0133244 METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL
The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such...
2018/0133243 METHOD AND COMPOSITION FOR CRUDE FORMULATIONS OF FORTIFIED SUGAR FOR GLYCEMIC CONTROL
A composition for glycemic control includes a sweetening agent, a polyphenol, and a starch. Examples of two formulations include but are not limited to i) a...
2018/0133242 COMPOSITION AND METHOD FOR PROMOTING REDUCTION OF HEAT STRESS IN ANIMALS
Disclosed herein is a method for promoting reduction of heat stress in animals, as well as a composition for use in the disclosed method. The composition...
2018/0133241 DEOXYNUCLEOSIDE THERAPY FOR DISEASES CAUSED BY UNBALANCED NUCLEOTIDE POOLS INCLUDING MITOCHONDRIAL DNA...
The invention relates generally to a pharmacological therapy for human genetic diseases, specifically those characterized by unbalance nucleotide pools, more...
2018/0133240 ONCE-DAILY TREATMENT OF PULMONARY FIBROSIS
The present invention relates to a compound of formula (I) for use in a method for treatment of pulmonary fibrosis in a human including administering...
2018/0133239 THERAPEUTIC COMPOSITION
This invention relates to a topical composition for prevention and treatment of viral infections.
2018/0133238 ORAL ADMINISTRATION OF ANTHOCYANINS, ANTHOCYANIDINS, AND THEIR METABOLITES FOR THE TREATMENT OF INFLAMMATION IN...
The invention provides methods of reducing inflammation and improving the catabolic/anabolic state to promote healing of the cartilage in a joint by providing...
2018/0133237 Enrichment Methods for Preparing Tannic Acid Compositions
Methods for preparing tannic acid-containing compositions (e.g., pharmaceutical compositions, nutraceutical compositions or medical food compositions),...
2018/0133236 CHEMOEMBOLISATION
A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein...
2018/0133235 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
2018/0133234 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
2018/0133233 BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS
Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphin-gosine analogs that, after phosphorylation, can...
2018/0133232 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING COMPLEX REGIONAL PAIN...
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2018/0133231 MINOCYCLINE COMPOUNDS FOR BIODEFENSE
Methods of treating or preventing a bacterial infection in a subject are disclosed herein, wherein the bacterial infection is caused by a bacterium which can...
2018/0133230 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS
A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group...
2018/0133229 ANTICONVULSANT ACTIVITY OF STEROIDS
The present invention relates to methods of preventing, inhibiting, delaying, and/or mitigating seizures by administration of a steroid, e.g., a neurosteroid,...
2018/0133228 Human papilloma virus replication inhibitors
Novel antiviral compounds for inhibiting one or more phases of HPV replication cycle are disclosed. Moreover, a mechanism for the inhibition is suggested and...
2018/0133227 COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION
Provided herein are pharmaceutical compositions that are useful for the treatment of hypertension comprising an angiotensin II receptor blocker, a diuretic, a...
2018/0133226 COMBINATION OF A PHOSPHATIDYLINOSITOL-3-KINASE (PI3K) INHIBITOR AND A MTOR INHIBITOR
The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound of formula (I) and (b) a mTOR...
2018/0133225 THERAPEUTIC COMPOUNDS AND USES THEREOF
Described herein are compounds of Formula (I) or Formula (VI), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also...
2018/0133224 METHOD FOR TREATING CANCER
The present invention provides a method for treating or alleviating a symptom of a disorder, e.g., immune evasion, cancer-cell induced immune dysfunction,...
2018/0133223 COMBINATION THERAPY WITH A PHOSPHOINOSITIDE 3-KINASE INHIBITOR WITH A ZINC BINDING MOIETY
The invention provides a method of treating cancer in a subject in need thereof, comprising administering to the subject: (a) a compound of Formula I: ...
2018/0133222 METHODS OF TREATING PEDIATRIC CANCERS
A method of treating a pediatric cancer in a subject in need thereof. The method includes administering to the subject a therapeutically effective amount of...
2018/0133221 ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND CHEMOTHERAPEUTIC AGENTS
Disclosed are methods for the treatment of cancer in patients in need of such treatment. The methods comprise administering to such a patient an ...
2018/0133220 COMPOUNDS FOR USE IN TREATING ACUTE CORONARY SYNDROME AND RELATED CONDITIONS
Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for acute coronary syndrome and related disorders.
2018/0133219 BIHETEROARYL COMPOUNDS AND USES THEREOF
The present invention provides for compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases)....
2018/0133218 FORMULATIONS, METHODS, KIT, AND DOSAGE FORMS FOR TREATING BACTERIAL INFECTION
Pharmaceutical formulations for treating bacterial or fungal infections comprising iclaprim or its enantiomers and a sulfonamide antibiotic, and treatment and...
2018/0133217 TOPICAL FORMULATIONS AND USES THEREOF
Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and...
2018/0133216 IMMEDIATE RELEASE PHARMACEUTICAL FORMULATION OF ...
The present invention relates to a pharmaceutical formulation comprising the drug 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-ben- ...
2018/0133215 SOMCL-9112 SOLID DISPERSION AND PREPARATION METHOD THEREOF AND SOMCL-9112 SOLID PREPARATION CONTAINING...
Disclosed is an SOMCL-9112 solid dispersion. The SOMCL-9112 solid dispersion is characterized by being prepared from the following raw materials in percentage...
2018/0133214 PHARMACEUTICAL COMPOSITION FOR TREATING CANCER AND A METHOD OF USING THE SAME
The invention provides a pharmaceutical composition and a method for treating cancer, and the composition comprises a proteasome inhibitor and a nuclear export...
2018/0133213 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
Provided herein are compounds of the Formula I: ##STR00001## and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X.sup.1,...
2018/0133212 COMBINATION OF A BCL-2 INHIBITOR AND A BROMODOMAIN INHIBITOR FOR TREATING CANCER
Provided herein are methods and compositions for the treatment of cancer. In particular, the methods include administration of a Bcl-2 inhibitor and a BET...
2018/0133210 TRANSMUCOSAL DELIVERY DEVICES WITH ENHANCED UPTAKE
The present invention provides methods for enhancing transmucosal uptake of a medicament, e.g., fentanyl or buprenorphine, to a subject and related devices....
2018/0133209 COMBINATION OF LAQUINIMOD AND PRIDOPIDINE FOR TREATING NEURODEGENERATIVE DISORDERS, IN PARTICULAR HUNTINGTON'S...
This invention provides a method of treating a patient afflicted with a neurodegenerative disorder, e.g., Huntington's disease (HD), comprising administering...
2018/0133208 CANCER TREATMENT VIA REPOSITIONED TRICYCLIC ANTI-DEPRESSANT-LIKE DRUGS AS ANTI-CANCER AGENTS AND NEW...
Methods and compositions for treating a lysosomal movement associated disease in an animal, in which the position of lysosomes can influence disease...
2018/0133207 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
Provided herein are compounds of the Formula I: ##STR00001## or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X.sup.1, X.sup.2, X.sup.3,...
2018/0133206 Treatment of CNS Disorders Associated with Mutations in Genes Encoding Lysosomal Enzymes
Described is a method for treating an individual having a neurological disorder with an associated mutation or mutations in a gene encoding a lysosomal enzyme....
2018/0133205 COMPOUND IMPURITIES AND METHODS OF DETECTING SAME
The present disclosure relates to compositions comprising impurities (e.g., carbamate and/or hydrolysis products) in a lomitapide sample and methods of...
2018/0133204 5-DEUTERO-2,4-THIAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME
The invention provides 5-deuterium-enriched 2,4-thiazolidinediones (e.g., 5-[4-[2-(5-ethyl-2-pyridyl)-2-oxoethoxy]benzyl]-5-deutero-thiazolidine-2,- 4-dione),...
2018/0133203 METHODS OF TREATING LIVER DISEASE
The present disclosure relates to a method of preventing and/or treating liver disease comprising administering an ASK1 inhibitor in combination with a FXR...
2018/0133202 2,4-Thiazolidinedione Derivatives in the Treatment of Central Nervous System Disorders
The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy)benzyl)thiazolidine-2,4-d- ione and novel stereoisomers of said compound for use...
2018/0133201 METHODS AND COMPOSITIONS FOR TREATING GASTRIC ULCERS
A method of treating and/or preventing gastric ulcers, said method comprising administering by injection a therapeutically effective amount of a composition...
2018/0133200 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
Provided herein are compounds of the Formula I: ##STR00001## and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X.sup.1,...
2018/0133199 SINGLE-DOSE, READY-TO-USE INJECTABLE FORMULATIONS
Provided are single-dose, ready-to-use formulations and methods for preparing the formulations that include a compound of Formula (I) ##STR00001## including...
2018/0133198 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS
The present invention provides compounds of Formula (I): ##STR00001## or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the...
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