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Patent # Description
2018/0140633 METHODS OF TREATING A TREATMENT-RESISTANT GASTROINTESTINAL SPASM WITH AN OXIDIZED TANNIN
Methods of treating a gastrointestinal spasm in a subject are provided. The methods can include administering an effective amount of a formulation to treat the...
2018/0140632 NUTRITIONAL SUPPLEMENT FOR GROWTH ENHANCEMENT
Provided are nutritional supplements designed for enhancing the growth, particularly the linear growth, of pre-pubertal children with a stature measure short...
2018/0140631 AMORPHOUS CALCIUM CARBONATE STABILIZED WITH POLYPHOSPHATES OR BISPHOSPHONATES
The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a...
2018/0140630 COMBINATION OF AN H2-RECEPTOR ANTAGONIST, ANTACID, AND ALGINIC ACID TO TREAT EPISODIC HEARTBURN
A combination of an antacid, alginate, and a histamine H.sub.2-receptor antagonist, and methods of using the same for providing fast and lasting relief of...
2018/0140629 IN VITRO BIO-REACTOR CIRCUIT
Embodiments of the invention provide bio-reactor circuits for in vitro research applications. One embodiment provides a bio-reactor circuit comprising at least...
2018/0140628 COMPOSITION INCLUDING GLYCOSAMINOGLYCAN DERIVATIVE AND CHEMOKINE RECEPTOR ACTIVITY REGULATOR
Provided are a composition comprising a GAG derivative and a chemokine receptor activity regulator, and a pharmaceutical composition comprising said composition.
2018/0140627 OLIGODEOXY NUCLEOTIDE FOR PREPARING DRUGS FOR INHIBITING TUMOR GROWTH AND APPLICATION THEREOF
The present invention provides an oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth and an application thereof. The core sequences of the...
2018/0140626 RETINOL-BINDING PROTEIN 3 (RBP3) AS A PROTECTIVE FACTOR IN NON-DIABETIC RETINAL DEGENERATION
Methods for increasing retinal thickness in a non-diabetic mammal, comprising administering to the mammal one or both of: (i) a composition comprising RBP3...
2018/0140625 PRODUCTION OF STABLE NON-POLYADENYLATED RNAS
The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a...
2018/0140624 METHOD FOR IMPROVING KIDNEY AND/OR HEART FUNCTION IN PATIENTS WITH KIDNEY DISEASE
Disclosed herein is novel use of telbivudine for improving kidney and/or heart function of a subject suffering from a kidney disease, such as acute kidney...
2018/0140623 COMPOSITION FOR PREVENTING OR TREATING CERVICAL CANCER INCLUDING GYPENOSIDE LXXV
Provided are a pharmaceutical composition for preventing or treating cervical cancer including gypenoside LXXV or a pharmaceutically acceptable salt thereof as...
2018/0140622 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
2018/0140621 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING ARTHRITIS
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2018/0140620 Pharmaceutical Combinations of Organo-Arsenoxide Compounds and mTOR Inhibitors
The present invention relates to synergistic pharmaceutical combinations comprising organic arsenoxide compounds and mTOR inhibitors. Further, the present...
2018/0140619 COMPOSITIONS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS INTO THE COLON
Enema compositions containing corticosteroids or salicylic acid derivatives are disclosed. The compositions are liquid at room temperature but turn to gels at...
2018/0140618 ANTICANCER ADJUVANT CONTAINING PANAXADIOL GINSENOCIDE COMPOUND
The present invention relates to an anticancer adjuvant containing, as an active ingredient, protopanaxadiol (PPD) or a compound-K, which are types of...
2018/0140617 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING PERIPHERAL DEMYELINATING DISEASES
The present invention relates to methods and pharmaceutical compositions for treating peripheral demyelinating diseases. In particular the present invention...
2018/0140616 METHODS OF TREATMENT OF, AND FORMULATIONS FOR TREATMENT OF ANORECTAL AND GENITOURINARY CONDITIONS
This invention relates to a novel method of treating various inflammation-related anorectal and genitourinary conditions using various related, novel...
2018/0140615 METHOD OF MANUFACTURING CORTICOSTERIOD CONTAINING FOAM COMPOSITIONS
The present invention provides a method of manufacturing foamable, corticosteroid containing compositions as well as methods for treating various skin diseases.
2018/0140614 CORTICOSTERIOD CONTAINING FOAM COMPOSITIONS
The present invention provides a method of manufacturing foamable, corticosteroid containing compositions as well as methods for treating various skin diseases.
2018/0140613 Metal Delivery Agents and Therapeutic Uses of the Same
The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the...
2018/0140612 TOPICAL OPHTHALMIC FORMULATIONS FOR THE TREATMENT AND PREVENTION OF MIGRAINE HEADACHE
The present invention provides topical ophthalmic formulations comprising a combination of one or more antihistamine agents and optionally one or more...
2018/0140611 Combination Therapy of Cardiac Myosin Activator and Sinus Node If Current Inhibitor
Disclosed herein are combination therapies for the treatment of heart failure using a cardiac myosin activator, such as omecamtiv mecarbil, and a sinus node If...
2018/0140610 OPIPRAMOL PATCH
Disclosed herein are compositions that are useful in effecting the transdermal delivery of active agents such as opipramol. More particularly, the disclosed...
2018/0140609 USE OF (4-HYDROXY-2-METHYL-1,1-DIOXIDO-2H-BENZO[E][1,2]THIAZINE-3-YL)(NAPH- THALENE-2-YL) METHANONE IN THE...
The present invention relates to (4-hydroxy-2-methyl-1,1-dioxido-2H-benzo[e][1,2]thiazine-3-yl)(naphthalen- -2-yl)methanone or one of the salts thereof,...
2018/0140608 METHOD
The present invention relates to a method of treating pain in a patient in need of such treatment, said method comprising administering to said patient a...
2018/0140607 HYDROXYL PURINE COMPOUNDS AND USE THEREOF
Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNF.alpha. inhibitors, in particular, the compounds as shown in formula (I),...
2018/0140606 In Vivo Chemoselection with Low Dose Thioguanine
The present disclosure is directed to methods of selecting for modified stem cells in vivo. The present disclosure is also directed to a 6TG dosing schedule....
2018/0140605 COMPOSITIONS AND METHODS INVOLVING POLYMER, SOLVENT, AND HIGH VISCOSITY LIQUID CARRIER MATERIAL
Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent....
2018/0140604 METHODS OF DIAGNOSING AND TREATING CANCER
A variety of different point mutations in NTRK1, NTRK2, and NTRK3 were identified in biopsy samples from a subjects having a variety of different cancers....
2018/0140603 POLYMORPHS OF ARRY-380, A SELECTIVE HER2 INHIBITOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Polymorphs of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dim- ethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine are provided...
2018/0140602 COMBINATION OF CHIMERIC ANTIGEN RECEPTOR THERAPY AND AMINO PYRIMIDINE DERIVATIVES
The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell...
2018/0140601 Neuroprotective Bicyclic Compounds and Methods for Their Use in Treating Autism Spectrum Disorders and...
Embodiments of this invention provide compositions and methods for therapeutic use of diketopiperazines including cyclic G-2-Allyl Proline and other cyclic...
2018/0140600 DEUTERATED DEHYDROPHENYLAHISTIN COMPOUNDS AND PREPARATION METHOD THEREOF AND USE THEREOF IN PREPARATION OF...
Provided are a deuterium-substituted dehydrophenylahistin-like compound, preparation method thereof and use in a preparation of antitumor drugs. The...
2018/0140599 PREVENTION AND/OR TREATMENT OF CONTRAST-INDUCED ACUTE KIDNEY INJURY
Methods are provided for preventing, reducing, and/or treating contrast-induced acute kidney injury which include administering an inhibitor of fatty acid...
2018/0140598 TREAMENT OF T-CELL MEDIATED DISEASES
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The...
2018/0140597 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL INFECTIONS IN PATIENTS SUFFERING FROM...
The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections in patients suffering from cirrhosis. In...
2018/0140596 New Pharmaceutical use and Pharmaceutical composition of pyrroloquinoline quinine, its derivatives and/or its salts
The present invention relates to the use of pyrroloquinoline quinine (PQQ), its derivatives and/or salts for the preparation of drugs for the treatment and/or...
2018/0140595 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases...
2018/0140594 TREATMENT OF LUPUS NEPHRITIS USING LAQUINIMOD
This invention provides a method of treating a subject afflicted with active lupus nephritis comprising periodically administering to the subject an amount of...
2018/0140593 Treatment of Glaucoma Using Laquinimod
The subject invention provides a method of treating a subject afflicted with glaucoma, suffering from retinal ganglion cell (RGC) loss or damage, or elevated...
2018/0140592 5-CHLORO-4-HYDROXY-1-METHYL-2-OXO-N-PHENYL-1,2-DIHYDROQUINOLINE-3-CARBOXAM- IDE, SALTS AND USES THEREOF
The subject invention provides 5-chloro-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxa- mide, its salts and uses.
2018/0140591 ORAL DELIVERY VEHICLE CONTAINING NICOTINE
The invention relates an oral delivery vehicle tablet containing nicotine, the delivery vehicle tablet being formed by compression of a plurality of particles,...
2018/0140590 Method of Treating Substance Addictions
A pharmaceutical composition containing isomyosmine or a pharmaceutically acceptable salt thereof is administered to an individual in need thereof for treating...
2018/0140589 ADMINISTRATION OF DIPEPTIDYL PEPTIDASE INHIBITORS
Pharmaceutical compositions comprising 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-p- yrimidinyl]methyl]-benzonitrile and...
2018/0140588 Method of Providing Pirfenidone Therapy to a Patient
The invention relates to methods for decreasing adverse events associated with pirfenidone (5-methyl-1-phenyl-2-(1H)-pyridone) therapy. The invention discloses...
2018/0140587 METHOD OF TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS
A method of treating focal segmental glomerulosclerosis with a compound of Formula I is provided. FSGS may be primary (no known cause) or secondary. The...
2018/0140586 METHODS OF TREATING DEVELOPMENTAL DISORDERS AND/OR SEIZURE DISORDERS WITH FLUPIRTINE
Methods of treating developmental disorders and/or seizure disorders with flupirtine or a pharmaceutically acceptable salt thereof are provided. The methods...
2018/0140585 BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE
The invention relates to panels of biomarkers including proteins phosphatase 1 regulatory subunit 14A and/or 2',3'-cyclic-nucleotide 3'-phosphodiesterase...
2018/0140584 MACROPINOCYTOSIS IN CANCER
Disclosed herein are compositions and methods for detecting and treating cancer. In some embodiments, the cancer is characterized by activation of Ras.
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