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Patent # Description
2018/0147308 STERILIZING SHEET
A sterilizing sheet is excellent in terms of saving space when a sterilizing operation is being performed, and sterilizing objects of various sizes. This...
2018/0147307 METHODS FOR STERILIZING COMPOSITIONS AND RESULTING COMPOSITIONS
Method for sterilizing a hydrogel composition include subjecting the composition to pulsed light comprising broadband spectrum radiation, the pulsed light...
2018/0147306 SYSTEMS AND METHODS FOR CONTROLLING AN IRRADIATION DEVICE
A method and system for treating a biological fluid within a container by subjecting the container to light is provided. The system includes a fluid treatment...
2018/0147305 Risk Stratification
The present invention relates to a method of in vivo imaging with meta-[.sup.123I]iodobenzylguanidine ([.sup.123I]mIBG) and more particularly wherein said...
2018/0147304 Risk Stratification
The present invention relates to a method of in vivo imaging with meta-[.sup.123I]iodobenzylguanidine ([.sup.123I]mIBG) and more particularly wherein said...
2018/0147303 MULTIVALENT TARGETING FLUORESCENT TRACER IN THE NEAR INFRARED RANGE FOR OPTICAL IMAGING
A fluorescent tracer for targeting tumors, comprises: at least one first fluorophore fluorescing in a range of wavelengths of between 700 and 1000 nm, a...
2018/0147302 COMPOSITIONS AND METHODS FOR MONITORING BIOMETRIC INDICATORS
Methods of measurement of biometric indicators in a mammalian subject are described. Biometric indicators of interest include hematocrit, plasma volume, volume...
2018/0147301 SOLID ORAL COMPOSITION CONTAINING DYES
The present invention relates to methods for improving the detection of pathologies in the colon and method of flagging the mucosal lesions in the colon.
2018/0147300 GLUCOCEREBROSIDASE GENE THERAPY FOR PARKINSON'S DISEASE
The present invention is directed, in part, to the treatment of a subject having a neurodegenerative disorder, such as Parkinson's disease (PD), by providing...
2018/0147299 GENE THERAPY VECTOR SYSTEM AND PRODRUG GENES
The present invention relates to a replication retrovirus vector system comprising thymidine kinase (HSV-TK) gene and cytosine deaminase (CD) gene which make...
2018/0147298 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS
This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo...
2018/0147297 PREPARATION OF SOLID CYCLODEXTRIN COMPLEXES FOR OPHTHALMIC ACTIVE PHARMACEUTICAL INGREDIENT DELIVERY
The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of...
2018/0147296 CARBON MATERIAL DELIVERY SYSTEMS AND METHODS
The present disclosure is directed to carbon nanomaterials and methods for delivering a drug to a mammal's cell including administering the carbon nanomaterial...
2018/0147295 Trimaleimide Linkers and Uses Thereof
A type of trimaleimide linkers and uses thereof are disclosed. The trimaleimide linkers can be applied for preparation of antibody-drug conjugate as shown by...
2018/0147294 ANTIBODY-DRUG CONJUGATES, COMPOSITIONS AND METHODS OF USE
Antibody-cytotoxin antibody-drug conjugates and related compounds, such as linker-cytotoxin conjugates and the linkers used to make them, tubulysin analogs,...
2018/0147293 ANTIGEN BINDING PROTEINS
The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA...
2018/0147292 METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE
A method for producing an antibody-drug conjugate composition, comprising: (i) a step of reacting an antibody with a reducing agent in a buffer to reduce...
2018/0147291 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS
This disclosure features compounds that are useful as pro-drugs of epoxy ketone protease inhibitors.
2018/0147290 NEW ANTIBACTERIAL PRODUCTS
The invention provides a combination of an antibacterial agent (in particular vancomycin or moenomycin) and a delivery agent, in which the delivery agent is...
2018/0147289 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers
This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the...
2018/0147288 CHEMOSELECTIVE MODIFICATION OF A CARRIER PROTEIN WITH A STRAINED ALKYNE-LABELED CARGO AGENT
Pharmaceutical compositions are provided for extending the serum half-life of a therapeutic agent. The composition may include a strained alkyne-labeled...
2018/0147287 Composition and Method for the Protection of Proteins, Cell Components and Cells During Temperature Stress
Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more...
2018/0147286 BONE FRACTURE REPAIR BY TARGETING OF AGENTS THAT PROMOTE BONE HEALING
Aspects of the present disclosure generally relate to compounds for targeting and healing bone fractures. Some of these compounds include a negatively charged...
2018/0147285 LIQUID COMPOSITIONS
Compositions useful in the treatment of cough and cold symptoms, including but not limited to, cough, nasal congestion and sore throat, are disclosed.
2018/0147284 Amorphous Metal-Organic Frameworks
The invention provides an amorphous metal-organic framework for use in methods of treatment. The amorphous metal-organic framework may hold a component for...
2018/0147283 OPHTHALMIC COMPOSITION COMPRISING LIPOIC ACID AND A MUCOMIMETIC POLYMER
The present invention relates to an ophthalmic composition in the form of an oil-in-water emulsion comprising a mucomimetic polymer and lipoic acid as emulsion...
2018/0147282 IRINOTECAN-LOADED DUAL-REVERSE THERMOSENSITIVE HYDROGEL COMPOSITION
Provided is an irinotecan-loaded dual-reverse thermosensitive formulation, which is a dual-reverse thermosensitive hydrogel composition including nanoparticles...
2018/0147281 NOVEL ANTI-HUMAN NGF ANTIBODY FAB FRAGMENT
To provide a superior anti-human NGF antibody Fab fragment that maintains a high neutralizing activity, and that reduces systemic side-effects arising from...
2018/0147280 METHOD OF AVERTING OPIOID ADDICTION
A method of averting opioid addiction in a patient is disclosed. The method can be applied to a patient suffering from moderate to severe low back pain (LBP)....
2018/0147279 COMBINATION THERAPY FOR NON-SMALL CELL LUNG CANCER POSITIVE FOR EGFR MUTATION
The present invention features methods of treating lung cancer (e.g., NSCLC) with an anti-PD-L1 antibody and a tyrosine kinase inhibitor in a subject...
2018/0147278 VACCINE AGAINST PORCINE PARVOVIRUS AND PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND METHODS OF...
The present invention relates to a porcine parvovirus and porcine reproductive and respiratory syndrome virus vaccine for protecting a subject, preferably...
2018/0147277 Peptide Sequences and Compositions
The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides,...
2018/0147276 ATTENUATED SWINE INFLUENZA VACCINES AMD METHODS OF MAKING AND USE THEREOF
This disclosure provides attenuated swine influenza strains, particularly those produced via a reverse genetics approach, compositions comprising same, and...
2018/0147275 CHIMERIC INFECTIOUS DNA CLONES, CHIMERIC PORCINE CIRCOVIRUSES AND USES THEREOF
The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs...
2018/0147274 IPN Virus Genome Mutations and Codon Interactions
The present invention relates generally to infectious pancreatic necrosis virus (IPNV) and specifically to further characterisation of the genetic stability of...
2018/0147273 METHODS FOR DISPLAYING POLYPEPTIDES AND USES THEREOF
Provided herein are methods and compositions for displaying a polypeptide on a tubular structure and uses of such displayed polypeptides in the production of...
2018/0147272 Vaccine Candidates Against Johne's Disease
A composition and method for immunizing a mammal infected with Mycobacterium are disclosed. The genes gcpE, pstA, kdpC, papA2, impA, umaA1, fabG2_2, aceAB,...
2018/0147271 ANTI-ROR1 CHIMERIC ANTIGEN RECEPTORS
The invention provides improved compositions for adoptive cell therapies for cancers that express ROR1.
2018/0147270 TUMOR ANTIGEN PEPTIDE
The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically...
2018/0147269 LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE
Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including...
2018/0147268 CYSTATIN C AND CYSTATIN 9 TO TREAT INFLAMMATION CAUSED BY BACTERIA
The present invention includes a composition and method for controlling an immune response in a host to a pathogenic bacterial infection comprising:...
2018/0147267 COMPOSITIONS AND METHODS FOR TREATING NEONATAL BILIARY ATRESIA
Disclosed are methods and compositions for treatment of a subject having a biliary disorder. The methods include administering a therapeutically effective...
2018/0147266 HIGHLY PURE NEUROTOXIC COMPONENT OF A BOTULINUM TOXIN, PROCESS FOR PREPARING SAME, AND USES THEREOF
The present invention relates to a process for preparing a highly pure neurotoxic component of a botulinum toxin by cultivating clostridium botulinum under...
2018/0147265 METHODS RELATING TO THE TREATMENT OF COLITIS AND INFLAMMATORY BOWEL DISEASE
The methods and compositions described herein relate to the treatment of bowel inflammation, e.g., IBD or a thrombosis, ischemia, and/or pulmonaryembolism...
2018/0147264 Endolysins Active Against Staphylococcus Bacteria, Pharmaceutical Compositions, and Methods Relating Thereto
The present invention relates to methods of treating or preventing a bacterial disease or infection, antibacterial compositions, and antibacterial surfaces,...
2018/0147263 METHOD OF TREATING NEUROLOGICAL DISORDER BY ENHANCING OUTGROWTH OF NEURITE
Disclosed herein is a method of enhancing the outgrowth of the neurite of a neuron in a subject. The present method comprises administering to the subject a...
2018/0147262 NOVEL SKIN MEDICAL AND COSMETIC CARE PRODUCT
Provided are novel skin medical and cosmetic care products as well as compositions for the treatment of the skin based on pulmonary surfactants.
2018/0147261 TREATMENT OF POST-BARIATRIC HYPOGLYCEMIA WITH GLP-1 ANTAGONISTS
Treatment of hyperinsulinemic hypoglycemia comprises administration of an effective amount of a glucagon-like peptide-1 receptor antagonist (GLP1RA) alone or...
2018/0147260 SYSTEMS AND METHODS FOR SYMPATHETIC CARDIOPULMONARY NEUROMODULATION
Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying...
2018/0147259 OLIGOPEPTIDE HAVING PROINFLAMMATORY CYTOKINE SECRETION-INHIBITING ACTIVITY
Provided is an oligopeptide having preventive and therapeutic effects on infarction diseases. The oligopeptide contains a DE loop sequence of RANKL protein,...
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