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Patent # Description
2018/0155401 Method for the Synthesis of Phycocyanin
The invention discloses microorganism cell culture conditions that result in increased cellular and media concentrations of a biological pigment. The invention...
2018/0155400 COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS
Provided herein are synthetic pathways from Escherichia coli and Vibrio cholerae genes for the production of new, synthetic nonribosomal peptides, and methods...
2018/0155399 TFPI INHIBITORS AND METHODS OF USE
The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. Peptide...
2018/0155398 Flavivirus-Binding, Entry-Obstructing, Protease-Resistant Peptide (RI57)
The invention pertains to inhibitors bindable to regions of a virus. More particularly, the invention relates to inhibitors bindable to regions of flaviviral...
2018/0155396 STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO CANCER THERAPEUTICS
This invention relates, e.g., to an inhibitory peptide or CPP inhibitor which specifically binds to p53 having an aberrant conformation (e.g., is aggregated or...
2018/0155395 PEPTIDOMIMETICS FOR IMAGING THE GHRELIN RECEPTOR
The present invention concerns compositions comprising and methods of identification and use of imaging agents. The imaging agents comprise a growth hormone...
2018/0155394 CANCER CELL-TARGETING PEPTIDE AND USE THEREOF
The present invention relates to a peptide targeting a tumor cell and use of the peptide, and more particularly, to a peptide consisting of SEQ ID NO: 1 to SEQ...
2018/0155393 HEPATITIS C VIRUS INHIBITORS
The present disclosure relates to methods for making asunaprevir, useful treatment of Hepatitis C virus (HCV) infection, and its intermediates.
2018/0155392 CYSTARGOLIDE COMPOUNDS AND USES THEREOF
There is provided herein compounds of formula I, wherein R.sub.1 is H or linear or branched C.sub.1-C.sub.6 lower alkyl; R.sub.2 is H, linear or branched...
2018/0155391 Method for extracting proteins and functional lipid from soybean liquid by directional continuous catalysis...
The present invention relates to fields of continuous directional catalysis of soybean slurry to extract protein and functional oil with nano-magnetic...
2018/0155390 SURFACE NEUTRALIZATION OF APATITE
The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
2018/0155389 STEROIDS AND PROTEIN-CONJUGATES THEREOF
Described herein protein steroid conjugates that are useful, for example, for the target-specific delivery of glucocorticoids (GCs) to cells.
2018/0155388 SELECTIVE PROGESTERONE RECEPTOR MODULATOR (SPRM) REGIMEN
The invention is directed to a pharmaceutical composition comprising a progesterone receptor antagonist namely ...
2018/0155387 PRODUCTION OF STEROLS
Method of recovering sterols from tall oil pitch which contains steryl esters. In the method the tall oil pitch is subjected to a transefterification reaction...
2018/0155386 PROGESTERONE ANTAGONISTS
Described herein are compounds which either act as pure antiprogestins or as antiprogestins with partial agonistic activity and methods of treating cancer...
2018/0155385 NUCLEOTIDES FOR THE TREATMENT OF CANCER
The present invention relates to novel nucleoside derivatives, pharmaceutical compositions comprising the compounds, processes of preparation thereof, and...
2018/0155384 SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF
Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such...
2018/0155383 ORGANOMETALLIC COMPOUNDS USEFUL FOR CHEMICAL PHASE DEPOSITION
Organometallic compounds, useful in chemical phase deposition processes, having a structure: [{R.sup.1R.sup.2R.sup.3(A))x-M(CO)y]z, wherein R.sup.1, R.sup.2...
2018/0155382 CYTOTOXIC PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC USE
Platinum(IV) complexes especially suitable for antitumor therapy and methods for their preparation. Further provided is a method for treating a subject, in...
2018/0155381 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
Metal complexes with cyclic ligands having Formula (I), ##STR00001## are disclosed. Ligands with cyclic structure are believed to be beneficial to the rigidity...
2018/0155380 PLATINUM COMPLEX, OLED AND APPARATUS FOR PROVIDING VISIBLE EMISSION OR NEAR-INFRARED EMISSION
A platinum complex, an OLED and an apparatus for providing visible emission or near-infrared (NIR) emission using the same are described. The platinum complex...
2018/0155379 Ruthenium Precursors For ALD And CVD Thin Film Deposition And Uses Thereof
Metal coordination complexes comprising a metal atom coordinated to at least one diazabutadiene ligand having a structure represented by: ##STR00001## where each...
2018/0155378 ANTIBACTERIAL BISMUTH COMPLEXES
Provided herein are organobismuth (III) phosphinate complexes, which comprise a phosphinate group and an aromatic carbocyclyl or aromatic heterocyclyl group....
2018/0155377 NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are...
2018/0155376 ALLYL-PHENOXY-CYCLOPHOSPHAZENE COMPOUND, AND PRODUCTION METHOD THEREFOR
An object of the present invention is to provide a mixture of cyclophosphazenes suitably substituted with phenoxy having a polymerizable functional group, such...
2018/0155375 NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are...
2018/0155374 BISPHOSPHONATES VINYLIC MONOMERS AND POLYMERS AND USES THEREOF
A compound or a polymer is claimed. A first formula can be ##STR00001## wherein X is H, CH.sub.3, CN, phenyl, substituted phenyl, (CH.sub.2).sub.mZ, or...
2018/0155373 Cysteine-Modifying Substrate Analogue Inhibitors of Ribose 5-Phosphate Isomerase for Parasitic Diseases, Along...
Compounds are generally provided, along with pharmaceutical compositions including such compounds. Methods are also generally provided for inhibiting ribose...
2018/0155372 TIN COMPOUND, METHOD OF SYNTHESIZING THE SAME, TIN PRECURSOR COMPOUND FOR ATOMIC LAYER DEPOSITION, AND METHOD...
A tin compound, tin precursor compound for atomic layer deposition (ALD), a method of forming a tin-containing material film, and a method of synthesizing a...
2018/0155371 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE
A process for preparing an acryloyloxysilane, comprising: reacting a metal salt of a carboxylic acid having the formula ...
2018/0155370 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT...
The present invention relates to: a thermosetting alkoxysilyl compound (hereinafter, referred to as "alkoxysilyl compound")having two or more alkoxysilyl...
2018/0155369 A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE
The instant invention provides a process for the preparation of bis(chloromethyl)dichlorosilane (BCMCS) or bis(chloromethyl) (aryl)chlorosilane (BCMACS)...
2018/0155368 METHOD FOR PREPARING L-BPA
Provided is a method for preparing L-BPA, which includes steps of: reacting N-protected (S)-4-halophenylalanine of Formula I, a boronating agent, Grignard...
2018/0155367 ETP DERIVATIVES
Provided herein, inter alia, is the synthesis of ETP derivatives. The uses of the ETP derivatives described herein include treatment of cancer.
2018/0155366 THIAZOLOPYRIMIDINONE COMPOUNDS AND PREPARATION METHODS AND USE THEREOF
The present invention provides structural details of a thiazolopyrimidinone compound, a preparation method thereof, and use thereof in the manufacture of a...
2018/0155365 TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS
The present invention relates to Tetracyclic Heterocycle Compounds of Formula (I). ##STR00001## and pharmaceutically acceptable salts or prodrug thereof, ...
2018/0155364 NOVEL PROCESS FOR THE PREPARATION OF DOLUTEGRAVIR AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
The present invention relates to a novel process for the preparation of dolutegravir and pharmaceutically acceptable salts thereof using novel intermediates.
2018/0155363 COMPOUNDS FOR THE TREATMENT OF ISCHEMIA-REPERFUSION-RELATED DISEASES
The present invention relates to compounds of formula (I) useful in the treatment of ischemia-reperfusion-related pathologies.
2018/0155362 MCL-1 INHIBITORS AND METHODS OF USE THEREOF
Disclosed is a compound which is 17-chloro-5,13,14,22-tetramethyl-28-oxa-2,9-dithia-5,6,12,13,22-pentaazah- ...
2018/0155361 PALLADIUM-MEDIATED KETOLIZATION
Provided herein are palladium-mediated coupling reactions useful in the preparation of ketone-containing organic molecules. The provided methods can be used...
2018/0155360 ETHER ANALOGUES OF GALIELLALACTONE
Ether analogues of galiellalactone, methods of preparing the analogues, and use of the analogues in the treatment of cancer are disclosed. The analogues are of...
2018/0155359 SHIP1 MODULATORS AND METHODS RELATED THERETO
Compounds of formula (II): ##STR00001## wherein ##STR00002## R.sup.1, R.sup.2, R.sup.5 and R.sup.13 are described herein, or a stereoisomer, enantiomer or...
2018/0155358 ERTUGLIFLOZIN CO-CRYSTALS AND PROCESS FOR THEIR PREPARATION
The present invention relates to processes for the preparation of an ertugliflozin-L-pyroglutamic acid (1:1) and co-crystal ertugliflozin-L-proline (1:1)...
2018/0155357 ISOSORBIDE DIESTER AS PEARLIZING AGENT AND OPACIFIER
A description is given of a composition comprising at least one isosorbide diester, at least one isosorbide monoester and at least one fatty acid, and also of...
2018/0155356 Crystals of Dispiropyrrolidine Derivatives
Crystals of a dispiropyrrolidine compound or a salt thereof which inhibits the action of Mdm2 are provided. The present invention provides crystals of ...
2018/0155355 CRYSTALS OF DISPIROPYRROLIDINE DERIVATIVES
Crystals of a dispiropyrrolidine compound or a salt thereof which inhibits the action of Mdm2 are provided. The present invention provides crystals of ...
2018/0155354 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
2018/0155353 Antimicrobial Compounds and Methods
Antimicrobial compounds are provided that are polymerizable. The compounds include monomers with antimicrobial properties. The compounds have cross-linking...
2018/0155352 CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pi- ...
2018/0155351 PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment...
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