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Patent # Description
2018/0155300 SOLID STATE FORMS OF TRISODIUM VALSARTAN: SACUBITRIL
Solid state forms of trisodium vaisartan:sacubitril, processes for their preparation, pharmaceutical compositions containing such solid state forms and...
2018/0155299 Azasteroidal Mimics
An azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic is formed via an oxocycloalkenyl isoxazolium anhydrobase and...
2018/0155298 PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS
The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of...
2018/0155297 INHIBITORS OF ACK1/TNK2 TYROSINE KINASE
Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of...
2018/0155296 SPIROCYCLOHEPTANES AS INHIBITORS OF ROCK
The present invention provides compounds of Formula (I): ##STR00001## or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the...
2018/0155295 CXCR4 CHEMOKINE RECEPTOR MODULATORS
Provided herein are small molecule modulators of CXCR4 activity (e.g., agonists, antagonists, inverse agonists, partial agonists), and methods of use thereof...
2018/0155294 FIPRONIL PRODUCTION PROCESS
An improved oxidation process for preparing 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethy- lsulphinyl-pyrazole, of formula (I) is...
2018/0155293 Substituted Heterocyclyl Derivatives as CDK Inhibitors
The present invention provides substituted heterocyclyl derivatives of formula (I), which are therapeutically useful, particularly as selective transcriptional...
2018/0155292 NOVEL 5-HT2 ANTAGONISTS
The present invention relates to 1-amidino-3-aryl-2-pyrazoline derivatives of the general formula I The invention specifically relates to such derivatives...
2018/0155291 NEW CRYSTAL FORM OF LENVATINIB METHANESULFONATE SALT AND PREPARATION METHOD THEREOF
The present disclosure relates to a novel crystalline form of lenvatinib mesylate and the preparation method thereof. The novel crystalline form of mesylate of...
2018/0155290 Improved Process for the Preparation of Aripiprazole with Reduced Particle Size
The present invention relates to process for preparation of Aripiprazole with reduced particle size having dehydro impurity less than 0.1%.
2018/0155289 MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF
This invention is in the field of medicinal chemistry. In particular, the invention relates to mixed disulfide conjugates of thienopyridine compounds, and...
2018/0155288 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof
There is provided a range of novel compounds which have been demonstrated to have useful electromagnetic radiation absorbing properties. These compounds will...
2018/0155287 COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN
The invention relates to the compounds of formula I, formula II, formula III, formula IV and formula V or its pharmaceutical acceptable polymorphs, solvates,...
2018/0155286 ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS
The present disclosure describes a method to treat conditions, including bacterial infections and cancer, using a photosensitive compound that, upon exposure...
2018/0155285 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES
Compounds of formula (I) as described hereinprocesses for their production and their use as anti-cancer agents. ##STR00001##
2018/0155284 PROCESSES TO PRODUCE BRIVARACETAM
The present invention provides a scalable synthesis of enantiomerically pure brivaracetam, and related derivatives.
2018/0155283 DOPAMINE D2 RECEPTOR LIGANDS
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the...
2018/0155282 PSYCHOTROPIC AGENTS AND USES THEREOF
Novel amisulpride derivatives and pharmaceutical compositions thereof are disclosed. The amisulpride derivative disclosed herein or a pharmaceutical...
2018/0155281 CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF
Disclosed herein are novel compounds of formula (I) as described herein: ##STR00001## and the use of such peptides in making immunoconjugates (i.e Antibody Drug...
2018/0155280 PREPOLYMERS EXHIBITING RAPID DEVELOPMENT OF PHYSICAL PROPERTIES
Hydroxyl-containing bis(alkenyl) ethers can be incorporated into the backbone of polythioether prepolymers and can be used as curing agents in thiol-terminated...
2018/0155279 ARYL ETHERS AND USES THEREOF
The present disclosure relates to HIF-2.alpha. inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in...
2018/0155278 METHOD FOR PREPARING TAURINE
There is disclosed a process for preparing taurine from alkali taurinate or a mixture of alkali taurinate, alkali ditaurinate and alkali tritaurinate by...
2018/0155276 PHTHALONITRILE COMPOUND
The present application can provide a phthalonitrile compound and a use thereof. The present application can provide a phthalonitrile compound capable of...
2018/0155275 A Novel Neuroprotective and Neurorestorative N-Propargyl Caffeamide (PACA) and Use as A Treatment for...
The present invention is directed to compounds, pharmaceutical compositions, and related methods of treatment and/or prevention for neurodegenerative diseases,...
2018/0155274 IDENTIFIABLE CHEMICAL PRODUCT
The invention is a process for manufacturing a chemical product which may be later identified and distinguished from similar chemical products, and comprises...
2018/0155273 CRYSTALLINE SOLID FORMS OF THE ACETATE SALT OF ...
The present invention is generally directed to novel crystalline forms of the acetate salt of ...
2018/0155272 PROCESS FOR RECOVERING AMINOALCOHOLS AND GLYCOLS FROM AQUEOUS STREAMS OF TAURINE PRODUCTION
There is disclosed an extraction process for recovering aminoalcohols and glycols from aqueous streams of taurine production. The aqueous streams which contain...
2018/0155271 SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES
The present disclosure describes methods for silylating aromatic organic substrates, and associated chemical systems, said methods comprising or consisting...
2018/0155270 PROCESS FOR PREPARATION OF CINACALCET INTERMEDIATE AND CINACALCET HYDROCHLORIDE
The present invention provides one pot process for preparation of highly pure unsaturated cinacalcet hydrochloride (II) comprising: i) converting ...
2018/0155269 METHOD OF PURIFYING NITRATED AROMATIC COMPOUNDS FROM A NITRATION PROCESS
A process for removing impurities from crude nitrated aromatic products obtained during the nitration of aromatic compounds. The nitrated aromatic products are...
2018/0155268 NOVEL PRODUCTION METHOD OF HIGHLY UNSATURATED FATTY ACID ETHYL ESTER
The present invention provides a method of producing/purifying highly unsaturated fatty acids and/or derivatives thereof while suppressing deterioration of a...
2018/0155267 7-METHYL-3-METHYLENE-7-OCTENAL ACETAL COMPOUND AND METHODS FOR PRODUCING ALDEHYDE COMPOUND AND ESTER COMPOUND...
There are provided methods of efficiently producing compounds that are, for example, sex pheromones of San Jose Scale. For example, there is provided a method...
2018/0155266 4-HYDROXYBUTYRIC ACID ANALOGS
This invention relates to novel derivatives of 4-hydroxybutyric acid and prodrugs thereof, and pharmaceutically acceptable salts of the foregoing. This...
2018/0155265 3,6-DICHLOROSALICYLIC ACID COMPOUNDS AND RELATED SYNTHETIC PROCESSES
The present disclosure relates, in general, to 5-halo-3,6-dichlorosalicylic acid compounds, 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for...
2018/0155264 CATALYTIC OXIDATION OF 3,5,5-TRIMETHYLCYCLOHEXA-3-ENE-1-ONE ( -ISOPHORONE) WITH HYDROGEN PEROXIDE TO AFFORD...
The present invention provides a novel process for producing 2,6,6-trimethyl-2-cyclohexene-1,4-dione (keto-isophorone) by catalytic oxidation of...
2018/0155263 METHODS AND CATALYSTS FOR CONVERTING METHANE TO METHANOL
The invention encompasses methods of directly converting methane- to methanol The invention further encompasses catalysts that efficiently afford this...
2018/0155262 OXIDATION OF LIMONENE
The invention discloses a process for the oxidation of limonene, comprising the reaction of limonene with hydrogen peroxide in the presence of a catalyst...
2018/0155261 METHOD FOR CONVERTING NATURAL GAS TO DIMETHYL ETHER
Systems and methods for upgrading natural gas that may include the division of a natural gas feed steam into two parts--one that is partially oxidized into...
2018/0155260 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN
The present invention provides a method for producing a target fluorine-containing olefin with high conversion and selectivity using a process comprising a...
2018/0155259 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUNDS
Provided is an efficient method for producing a fluorine-containing compound without the need for a rectification column involving numerous stages, extractive...
2018/0155258 ACETYLENE REMOVAL FROM LIGHT HYDROCARBON MIXTURES BY METAL-ORGANIC FRAMEWORK EXHIBITING DUAL SIZE AND CHEMICAL...
The present invention provides a gas separation system and a gas separation method capable of separating various types of hydrocarbon gas with high...
2018/0155257 TREATING C8-C10 AROMATIC FEED STREAMS TO PREPARE AND RECOVER TRANSMETHYLATED BENZENES
Methods are provided for the treatment of a feed stream containing C9 aromatic components to produce mesitylene-containing products. The methods include...
2018/0155256 DUAL CATALYST SYSTEM FOR PROPYLENE PRODUCTION
Embodiments of processes for producing propylene utilize a dual catalyst system comprising a mesoporous silica catalyst impregnated with metal oxide and a...
2018/0155255 Process of Producing Paraxylene by The Methylation of Toluene and/or Benzene
A process for producing paraxylene by the catalytic alkylation of benzene and/or toluene with methanol. In prior art processes, water is typically co-injected...
2018/0155254 METHOD FOR OLIGOMERIZATION OF OLEFINS (AMENDED)
The present disclosure relates to a method for oligomerization of olefins. The method for oligomerization of olefins according to the present disclosure not...
2018/0155253 Passive Digestion
This invention is a method for the processing of organic materials or organic wastes in a cost-effective and environmentally sound manner. The invention works...
2018/0155252 SYSTEMS AND METHODS FOR CERAMIC MATRIX COMPOSITES
Methods for fabricating a ceramic matrix composite are disclosed. A fiber preform may be placed in a mold. An aqueous solution may be added to the fiber...
2018/0155251 PRE-FORM BONDING AGENT FOR MAKING VITRIFIED PRODUCTS
Pre-form bonding agent for making vitrified products, said agent including sugar.
2018/0155250 METHOD OF MAKING AN ALUMINA-SILICATE OXYNITRIDE AND CUBIC BORON NITRIDE CERAMIC COMPOSITE
A method for producing a composite of cubic boron nitride dispersed in a SiAlON ceramic. This method involves mixing silicon nitride nanoparticles, aluminum...
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