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Patent # Description
2018/0153985 ADJUVANT COMPOSITION CONTAINING ALUMINUM AND VACCINE COMPOSITION CONTAINING THE SAME
The present invention relates to an adjuvant composition including a pH-sensitive carrier and an aluminum-containing substance. According to the present...
2018/0153984 ADJUVANT PARTICLES COMPRISING ADENOSINE RECEPTOR ANTAGONISTS
This document relates to polymeric particles for enhancing the immune response, compositions comprising the polymeric particles, and methods of use thereof....
2018/0153983 CONJUGATION OF STAPHYLOCOCCUS AUREUS TYPE 5 AND TYPE 8 CAPSULAR POLYSACCHARIDES
The invention provides a process for preparing a conjugate of a S.aureus type 5 or type 8 capsular polysaccharide and a carrier molecule, comprising the steps...
2018/0153982 COMPOSITIONS, METHODS AND KITS FOR ELICITING AN IMMUNE RESPONSE
The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in...
2018/0153981 COMPOSITION FOR INDUCING PROLIFERATION OR ACCUMULATION OF REGULATORY T CELLS
It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present...
2018/0153980 Inactivated Bacterial Cell Formulation
The invention relates to the use of lactic acid-producing bacteria to boost the immune system.
2018/0153979 MALARIA ANTIGENS AND METHODS OF USE
The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune...
2018/0153978 TUMORS EXPRESSING IgG1 Fc INDUCE ROBUST CD8 T CELL RESPONSES
A lymphoma cell line was engineered to express surface IgG1 Fc. These tumor cells were taken up rapidly by DCs, leading to enhanced cross-presentation of...
2018/0153977 HUMANIZED ANTI-CD19 ANTIBODY AND USE THEREOF WITH CHIMERIC ANTIGEN RECEPTOR
Embodiments herein relate to humanized CD19 antibodies and disease treatment using the antibodies. For example, a subject having a CD19 positive tumor may be...
2018/0153976 NOVEL CMV PP65 TARGETING DNA VACCINE FOR CANCER IMMUNOTHERAPY
The present invention relates to an attenuated strain of Salmonella comprising a DNA molecule encoding CMV pp65. In particular, the present invention relates...
2018/0153975 SHARED NEOANTIGENS
Disclosed herein in one aspect is a pharmaceutical composition comprising a plurality of neoantigenic peptides and a pharmaceutically acceptable carrier, each...
2018/0153974 Combination Therapies With Recombinant Listeria Strains
The disclosure is directed to compositions comprising an oncolytic virus, chimeric antigen receptor T cells (CAR T cells), a therapeutic or immunomodulating...
2018/0153973 DNA VACCINE AGAINST AMYLOID-BETA AND TAU
An object of the present invention is to provide a vaccine that can simultaneously reduce A.beta. deposition and tau deposition in the brain by means of a...
2018/0153972 C1-INH COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF DISORDERS ASSOCIATED WITH C1 ESTERASE...
Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
2018/0153971 METHODS OF REDUCING EXTRAVASATION OF INFLAMMATORY CELLS
A method for modifying access of cells to extravascular spaces and regions comprising administering to a patient an enzyme that cleaves chondroitin sulfate...
2018/0153970 COMPOSITION AND USES THEREOF
The invention relates to compositions comprising Pinus pinaster stem bark extract, papain, and Aloe vera extract, and methods of manufacturing same. There are...
2018/0153969 Process, Tube And Device For The Preparation Of Wound Healant Composition
The present invention is related to the field of tissue regeneration. It concerns more particularly new processes, tubes and devices for thrombin, platelet...
2018/0153968 METHODS FOR PREPARING MODIFIED VON WILLEBRAND FACTOR
The present invention provides modified von Willebrand Factor molecules, methods for their preparation and uses thereof. The invention further provides...
2018/0153967 PROCESS FOR PREPARING A POWDER COMPRISING A HUMAN COAGULATION FACTOR PROTEIN AND A LACTIC ACID POLYMER
A process for preparing a powder, which includes one or more human coagulation factor proteins and a lactic acid polymer, involves mixing and dispersing a...
2018/0153966 Assessment of Cardiac Health and Thrombotic Risk in a Patient
The invention features methods and compositions for assessing risk, particularly immediate risk, of thrombotic events in patients with suspected or known...
2018/0153965 Therapies for Obesity, Diabetes and Related Indications
The invention relates to methods, uses, compositions and formulations including a melanocortin receptor-4 agonist and a glucagon-like peptide-1 receptor...
2018/0153964 PHARMACEUTICAL COMPOSITION FOR TREATING SARCOPENIA INCLUDING GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST
Provided are a pharmaceutical composition for preventing or treating muscle atrophy or sarcopenia including glucagon-like peptide-1 (GLP-1), a GLP-1 fragment,...
2018/0153963 SURGICAL METHODS AND COMPOSITIONS TO FACILITATE REPAIR OF AVASCULAR TISSUE
Compositions and surgical methods are provided for repairing damaged avascular zones, including intervertebral disc, in a patient in need thereof.
2018/0153962 SYNERGISTIC COMBINATION OF NEURONAL VIABILITY FACTORS AND USES THEREOF
The present invention relates to the synergistic combination of the short and long Rod-Derived Cone Viability Factors and to methods for treating retinal...
2018/0153961 COMPOSITION COMPRISING KA11 POLYPEPTIDE OR GENE ENCODING THE SAME FOR INHIBITING ANGIOGENESIS, AND USE THEREOF
Provided is a composition including a KAI1 polypeptide or a gene encoding the same, for inhibiting angiogenesis, and a use thereof, and more specifically, a...
2018/0153960 IRISIN FOR CARE AND PREVENTION OF OSTEOPOROSIS
An object of the present invention is the use of Irisin for the treatment and/or prevention of osteoporosis. In particular, the present invention refers to the...
2018/0153959 PHARMACEUTICAL AND FOOD COMPOSITIONS FOR INDUCING SATIATION AND PROLONGING SATIETY IN SUBJECTS IN NEED THEREOF
The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular,...
2018/0153958 CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES
The present invention relates to novel cycloundecadepsipeptide compounds and their analogues which bind and inhibit cyclophilins, have reduced ...
2018/0153957 PREPARATIONS CONTAINING AMORPHOUS EMODEPSIDE
The invention relates to preparations comprising amorphous emodepside in a polyvinylpyrrolidone matrix, pharmaceuticals comprising such preparations, and their...
2018/0153956 IN SITU FORMING HYDROGEL AND METHOD USING SAME
A hydrogel (I), comprising a polymer backbone wherein an aqueous solution of the hydrogel comprises a first lower critical solution temperature, and wherein...
2018/0153955 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0153954 ABSORBENT STRUCTURE FOR ABSORBENT ARTICLES
Absorbent structures for absorbent articles are provided, comprising an absorbent layer with absorbent material containing superabsorbent polymer particles...
2018/0153953 METHODS OF TREATING PANCREATIC CANCER USING GPCR ANTAGONISTS
Provided herein are, inter alia, compositions and methods for the treatment of cancer and inhibition of metastasis. The compositions include a .mu.-opioid...
2018/0153952 COMPOSITIONS AND METHODS FOR TREATING POST OPERATIVE COGNITIVE DYSFUNCTION AND NEUROINFLAMMATION WITH ANNEXIN...
The present disclosure provides compositions and methods for treating post-operative cognitive dysfunction with Annexin A1 (ANXA1) peptides.
2018/0153951 Methods for Inducing Adipocyte Browning, Improving Metabolic Flexibility, and Reducing Detrimental White...
This disclosure relates to methods of inducing adipocyte browning, supporting metabolic flexibility, and/or reducing detrimental WAT deposition or reducing WAT...
2018/0153950 EURYCOMA LONGIFOLIA EXTRACT AND ITS USE IN ENHANCING AND/OR STIMULATING IMMUNE SYSTEM
A method for stimulating or enhancing the immune system with a composition that includes a Eurycoma longifolia aqueous extract. Also provided is a method for...
2018/0153949 COMPOSITION, CONTAINING QUISAQUALIS INDICA EXTRACT, FOR PREVENTING OR TREATING PROSTATIC HYPERPLASIA
A pharmaceutical composition comprises a Quisaqualis indica extract as an active ingredient, for preventing or treating prostatic hyperplasia, and may also be...
2018/0153948 SYSTEMS AND METHODS FOR EXTRACTION OF NATURAL PRODUCTS
Described herein, inter alia, are processes, methods, and compositions useful for the extraction of natural products from source materials.
2018/0153947 COMPOSITIONS AND METHODS FOR PREVENTING INFECTIONS
The present invention relates to a dietary supplement or pharmaceutical composition, comprising lyophylized Saccharomyces boulardii as an active ingredient and...
2018/0153946 ONCOLYTIC ADENOVIRUSES WITH MUTATIONS IN IMMUNODOMINANT ADENOVIRUS EPITOPES AND THEIR USE IN CANCER TREATMENT
The present invention relates to oncolytic adenoviruses with functional deletions of immunodominant T-cell epitopes of adenovirus proteins, as well as to...
2018/0153945 ORAL E. COLI VECTOR-BASED VACCINE FOR PREVENTION OF COCCIDIOSIS IN POULTRY
The invention relates to recombinant vaccines capable of presenting all, or antigenic portions of, the Eimeria tenella 3-1e, or profilin. Also provided are...
2018/0153944 METHODS FOR DETECTING RISK OF HAVING A BLOODSTREAM INFECTION AND COMPOSITIONS FOR REDUCING THE RISK
Provided herein is a method for determining the relative abundance of total bacterial in a sample. Optionally, the method also includes determining whether the...
2018/0153943 Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Device for Delivering Them
This application provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments, and methods for making, storing and...
2018/0153942 IONIZING IRRADIATION STERILIZATION OF BACTERIAL MINICELL-BASED BIOPHARMACEUTICALS AND METHODS OF USE
Disclosed herein are methods of terminally sterilizing bacterial minicells or compositions comprising bacterial minicells by exposure to ionizing irradiation....
2018/0153941 METHODS FOR GENERATING STEM CELL-DERIVED BETA CELLS AND USES THEREOF
Disclosed herein are methods for generating SC-.beta. cells, and isolated populations of SC-.beta. cells for use in various applications, such as cell therapy.
2018/0153940 COMPOSITIONS FOR TREATMENT OF OSTEOCHONDRAL DISORDERS
The application provides biocompatible carriers comprising bone forming and/or cartilage forming cells and methods for making them. The application further...
2018/0153938 NK Cells and Antibodies for Cancer Treatment
Treatment of cancer in a patient comprises administering to the patient an effective amount of an antibody and an effective amount of NK cells, wherein the...
2018/0153937 Inoculation by Applying Nanosecond Pulsed Electric Fields to a Biopsy And Reintroducing the Treated Biopsy to...
A subject is inoculated from a disease by exposing a biopsy of a tumor or other abnormal growth to a nanosecond pulsed electric field (nsPEF). A sufficient...
2018/0153936 COMPOSITIONS AND METHODS OF USING LAMELLAR BODIES FOR MODIFYING LINEAR BIOLOGICAL MACROMOLECULES
Compositions comprising therapeutically effective amounts of lamellar bodies to restore lubricity and non-stick properties to mucous surfaces for conditions...
2018/0153935 Medicinal Composition for Total Body Detoxification
A medicinal composition for total body detoxification is administered to a user to remove toxins from the user's body, as well as, provide hangover relief...
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