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Patent # Description
2018/0155754 METHODS AND DEVICES TO DETECT THE PRESENCE OF A CONDITION ASSOCIATED WITH ATP DEPLETION IN A SUBJECT
The invention provides a method of determining a predisposition to a condition associated with ATP depletion, such as an ischaemic event, in a subject...
2018/0155753 MANGANESE SUPPLEMENTATION FOR CONTROL OF GLYCOSYLATION IN MAMMALIAN CELL CULTURE PROCESS
The present invention pertains to a cell culture medium comprising manganese as a media supplement, which was shown to control recombinant protein...
2018/0155752 METHOD AND APPARATUS FOR ANTIBODY PRODUCTION AND PURIFICATION
The subject invention pertains to methods and apparatus for the production and purification of cell products, such as immunoglobulins. One aspect of the...
2018/0155751 FERMENTATION METHODS FOR PRODUCING STEVIOL GLYCOSIDES USING HIGH PH AND COMPOSITIONS OBTAINED THEREFROM
Disclosed are methods for producing steviol glycosides, such as rebaudioside D and rebaudioside M, using engineered yeast. In some embodiments, the methods...
2018/0155750 USE OF A CELLULOSE HYDROLYSATE FOR BIOGAS PRODUCTION
The present invention proposes a cellulose hydrolysis method including contacting a fermentation medium comprising paper sludge as carbon source with cellulase...
2018/0155749 PROCESS FOR PRODUCING ACYL AMINO ACIDS EMPLOYING LIPASES
There is provided a microbial cell for producing at least one acyl amino acid, wherein the cell is genetically modified to comprise: a first genetic mutation...
2018/0155748 FUSION PROTEINS USEFUL LN THE PRODUCTION OF CANNABINOIDS
The present invention is a method for the biosynthesis of hundreds of compounds, mainly found in the cannabis plant. The starting material for these compounds...
2018/0155747 Lactate Production Process
A process for producing alkyl R-lactate from an initial compound comprising substructure (I) ##STR00001## is provided. The process involves producing an...
2018/0155746 Method for material use of organic substrate
The invention relates to a method for obtaining at least one organic target product and biogas. The method is characterised in that a) organic substrate is...
2018/0155745 PROCESSING BIOMASS
Carbon-containing materials, such as biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) or coal are processed to produce useful...
2018/0155744 RECOMBINANT YEAST AND USE THEREOF
A recombinant yeast that expresses both an .alpha.-amylase (SEQ ID NO: 1) and a glucoamylase (SEQ ID NO: 2) from Talaromyces emersonii (recently re-named as...
2018/0155743 PRODUCTION OF PROPANOL AND/OR PROPIONIC ACID
The present invention relates to a method of producing propanol and/or propionic acid from a carbon source in aerobic conditions, the method comprising: (a)...
2018/0155742 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF BUTADIENE
The invention provides non-naturally occurring microbial organisms having a butadiene pathway. The invention additionally provides methods of using such...
2018/0155741 MICROBIAL DERIVED ISOPRENE AND METHODS FOR MAKING THE SAME
Provided herein is a gaseous isoprene composition comprising isoprene, carbon dioxide and water, wherein the isoprene is in an amount between about 0.1% and...
2018/0155740 RECOMBINANT BACULOVIRUS AND METHOD OF USING THE SAME FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR
A recombinant baculovirus, including: an adeno-associated virus Rep gene, an adeno-associated virus Cap gene, and an recombinant adeno-associated virus genome...
2018/0155739 COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS
Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or...
2018/0155738 CONSTITUTIVE PHOTOMORPHOGENESIS 1 (COP1) NUCLEIC ACID SEQUENCE FROM ZEA MAYS AND ITS USE THEREOF
The present invention relates to an isolated COP1 nucleic acid sequence from a maize plant and the isolated COP1 nucleic acid sequence is named as ZmCOP1. The...
2018/0155737 METHOD FOR MODULATING PLANT ROOT ARCHITECTURE
The present invention provides a method for modulating or inhibiting modulation of the root architecture of a plant employing a new class of root architecture...
2018/0155736 MANIPULATING PLANT SENSITIVITY TO LIGHT
The present disclosure identifies new genes which have the potential to increase broad acre yield in crops. This disclosure is based upon our fundamental...
2018/0155735 IDENTIFICATION OF TRANSCRIPTION FACTORS THAT IMPROVE NITROGEN AND SULPHUR USE EFFICIENCY IN PLANTS
The present invention provides an expression cassette comprising at least one polynucleotide comprising a nucleotide sequence selected from the group...
2018/0155734 Isolated Novel Nucleic Acid and Protein Molecules From Soy and Methods of Using Those Molecules to Generate...
This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of...
2018/0155733 A METHOD FOR PRODUCING RESVERATROL
Recombinant hosts and methods for producing resveratrol in recombinant hosts are disclosed herein.
2018/0155732 CONSTRUCTS AND METHODS FOR GENOME EDITING AND GENETIC ENGINEERING OF FUNGI AND PROTISTS
Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting...
2018/0155731 NANNOCHLOROPSIS SPLICED LEADER SEQUENCES AND METHODS OF USE THEREOF
The present invention relates to the culture and manipulation of microorganisms for biotech applications, and is based on the discovery and characterization of...
2018/0155730 Recombinant Microorganism Including Genetic Modification That Increases Activity Of Haloalkane Dehalogenase And...
Provided are a recombinant microorganism including a first genetic modification that increases activity of haloalkane dehalogenase (HAD) and a second genetic...
2018/0155729 METHODS AND COMPOSITIONS FOR EFFICIENT DELIVERY OF NUCLEIC ACIDS AND RNA-BASED ANTIMICROBIALS
The invention relates to the methods for modifying the methylation pattern of bacteriophage DNA and phagemid DNA and to methods for selective killing of...
2018/0155728 METHODS AND COMPOSITIONS FOR TRANSLATIONAL PROFILING AND MOLECULAR PHENOTYPING
Methods and compositions are provided for translational profiling and molecular phenotyping of specific tissues, cells and cell subtypes of interest. The...
2018/0155727 METHODS OF REDUCING OR PREVENTING INTIMAL DAMAGE CAUSED BY MECHANICAL STIMULATION OF ENDOTHELIAL CELLS
Embodiments of the disclosure encompass methods and/or compositions for ameliorating or preventing intimal damage caused by mechanical stimulation of...
2018/0155726 USE OF AN miRNA TO REDUCE PROLIFERATION OF A CANCER CELL
A method is provided for decreasing at least one of the proliferation and the migration of a cancer cell comprising contacting a cancer cell with an effective...
2018/0155725 Method for Generating Aptamers with Improved Off-Rates
The present disclosure describes improved SELEX methods for producing aptamers that are capable of binding to target molecules and improved photoSELEX methods...
2018/0155724 Materials and Methods for Modulation of Tendon Healing
The invention relates to the use of microRNA 29 and precursors and mimics thereof for the modulation of tendon injury and the biomechanical properties of...
2018/0155723 RESTORATION OF THE CFTR FUNCTION BY SPLICING MODULATION
Provided are oligonucleotides capable of binding to and modulating the splicing of the pre-mRNA of the CFTR gene, compositions including said oligonucleotides,...
2018/0155722 NOVEL BETA-ACTIN AND RPS21 PROMOTERS AND USES THEREOF
The invention relates to isolation of novel .beta.-actin promoters and uses thereof. In particular, this invention features nucleotide sequences for rodent...
2018/0155721 SYNTHETIC BACTERIOPHAGES AND BACTERIOPHAGE COMPOSITIONS
Disclosed herein are novel synthetic bacteriophages and bacteriophage compositions, methods of production thereof, and therapeutic uses thereof.
2018/0155720 ENGINEERED NUCLEIC ACID-TARGETING NUCLEIC ACIDS
The present disclosure provides engineered Class 2 CRISPR-Cas-associated discontinuous first-stem nucleic-acid targeting nucleic acids, nucleoprotein complexes...
2018/0155719 MICRORNA COMPOUNDS AND METHODS FOR MODULATING MIR-21 ACTIVITY
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield...
2018/0155718 RNA DUPLEXES WITH SINGLE STRANDED PHOSPHOROTHIOATE NUCLEOTIDE REGIONS FOR ADDITIONAL FUNCTIONALITY
The present invention relates to RNAi constructs and their use in gene silencing. RNAi constructs associated with the invention contain a double stranded...
2018/0155717 GENOMIC ENGINEERING OF PLURIPOTENT CELLS
Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites....
2018/0155716 NOVEL CRISPR ENZYMES AND SYSTEMS
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or...
2018/0155715 RNA-GUIDED TRANSCRIPTIONAL REGULATION AND METHODS OF USING THE SAME FOR THE TREATMENT OF BACK PAIN
Described herein are compositions and methods for treatment and prevention of low back pain. The compositions include vectors comprising nucleotide sequences...
2018/0155714 ONE-STEP SURFACE MODIFICATION TO GRAFT DNA CODES ON PAPER AND ITS BIO-APPLICATIONS
Embodiments described herein are related to a one-step surface modification method with 3-aminopropyl trimethoxysilane (APTMS), which was developed and applied...
2018/0155713 METHODS FOR RNA PROMOTER IDENTIFICATION
Provided are constructs and methods for RNA promoter identification.
2018/0155712 COMPOSITIONS AND METHODS FOR IDENTIFYING POLYNUCLEOTIDES OF INTEREST
Provided are constructs and methods useful for the screening and identification of polynucleotide sequences of interest, in particular promoters, RNA stability...
2018/0155711 SYNTHETIC AUXOTROPHS WITH LIGAND DEPENDENT ESSENTIAL GENES FOR BIOSAFETY
Synthetic auxotrophs with one or more ligand-dependent essential gene functions and methods of production that can be used for biosafety. The ligand-dependent...
2018/0155710 METHOD FOR SOLID-PHASE SYNTHESIS OF DNA ENCODED COMPOUND LIBRARY
The present invention provides a method of solid-phase synthesis of DNA-encoded compound library. The method includes following steps: a) reacting solid...
2018/0155709 SURFACE-BASED TAGMENTATION
Presented herein are methods and compositions surface-based tagmentation. In particular embodiments, methods of preparing an immobilized library of fragmented...
2018/0155708 Split Cas9 Proteins
Split Cas9 proteins, including an active nuclease, a nickase, and a nuclease-null Cas9 protein, are provided. The Cas9 proteins were derived from nucleic acids...
2018/0155707 Methods For Separating Nucleic Acids With Graphene Coated Magnetic Beads
Methods for separating and identifying nucleic acids utilize carbon coated magnetic beads. The method teaches that multivalent cations promote binding of...
2018/0155706 Method And Device For Disaggregation Via Heterogeneous Particles
A method and a device are provided for facilitating the disaggregation of a plurality of solid phase substrate as the plurality of solid phase substrate are...
2018/0155705 METHOD FOR ISOLATING EXTRACELLULAR NUCLEIC ACIDS USING ANION EXCHANGE PARTICLES
The present invention pertains to methods and kits for isolating extracellular nucleic acids from a biological sample using anion exchange particles. It was...
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