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Patent # Description
2018/0155704 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF...
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements...
2018/0155703 RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF
The present invention relates to methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins....
2018/0155702 MULTIPLY-SUBSTITUTED PROTEASE VARIANTS
Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in...
2018/0155701 PROTEASES WITH MODIFIED PROPEPTIDE REGIONS
The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include...
2018/0155700 HETEROLOGOUS EXPRESSION OF TERMITE CELLULASES IN YEAST
The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be...
2018/0155699 BETA-GALACTOSIDASE VARIANT HAVING HIGH TRANSGLYCOSYLATION ACTIVITY, AND USE THEREOF
The present invention relates to a beta-galactosidase mutant having high transglycosylation activity and containing a C-terminal deletion, and the use thereof...
2018/0155698 POLYMERASES ENGINEERED TO REDUCE NUCLEOTIDE-INDEPENDENT DNA BINDING
Provided are engineered DNA polymerases exhibiting modified functionality, and polynucleotides encoding same. Modified features include: (1) reduced catalytic...
2018/0155697 METHOD OF PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS AND RECOMBINANT BACULOVIRUS
A method for producing a recombinant adeno-associated virus (rAAV) and a recombinant baculovirus virus, the method including: (1) infecting an insect host...
2018/0155696 METHODS AND COMPOSITIONS RELATING TO VIRAL LATENCY
Disclosed are compositions and methods that relate generally to viruses, and more particularly to the agents and their identification and use of anti-HIV...
2018/0155695 Cell Having Ability to Form Stratified Epithelial Tissue, and Method for Producing Same
To convert directly from a somatic cell into a cell having the ability to form stratified epithelial tissue that can act as outer skin of the body, a method...
2018/0155694 METHODS OF PRODUCING PLURIPOTENT STEM CELLS FROM CHONDROCYTES
Disclosed herein are methods of producing induced pluripotent stem cells from chondrocytes, and further, methods of producing chondrocytes from said induced...
2018/0155693 Method of Differentiating Stem Cells
There is provided an improved efficient method for differentiating stem cells into pancreatic endoderm cells and pancreatic hormone expressing and secreting...
2018/0155692 METHODS AND COMPOSITIONS FOR CONVERTING NON-ENDOCRINE PANCREATIC TISSUE INTO INSULIN-PRODUCING CELLS
Compositions and methods are provided for generating islet-like cell clusters. The methods include culturing a whole non-islet pancreatic cell discard or cells...
2018/0155691 MECHANICAL APPARATUS AND METHOD FOR ISOLATING STROMAL VASCULAR FRACTION
Provided is an apparatus and process for isolation of stromal vascular fraction (SVF) following lipoaspiration.
2018/0155690 METHOD FOR PREPARING NATURAL KILLER CELLS USING IRRADIATED PBMCS, AND ANTI-CANCER CELL THERAPEUTIC AGENT...
Provided is a method for preparing natural killer cell with high efficiency using irradiated peripheral blood mononuclear cells, more particularly to a method...
2018/0155689 METHOD FOR IN VITRO EXPANSION OF ERYTHROID CELLS
The present invention relates to a method for in vitro expansion of mature erythroid cells. More specifically, the present invention relates to a method for...
2018/0155688 METHOD FOR GENERATING HUMAN DENDRITIC CELLS FOR IMMUNOTHERAPY
In various embodiments methods of producing a cell population enriched for CLEC9A+ dendritic cells are provided where the methods involve culturing stem cells...
2018/0155687 HORMONE RESPONSIVE TISSUE CULTURE SYSTEM AND USES THEREOF
The invention provides tissue culture system for primary cells (e.g. normal mammalian primary epithelial progenitors). This system includes: a) a serum-free,...
2018/0155686 MEANS AND METHODS FOR GENERATION OF BREAST STEM CELLS
The present invention is in the field of stem cell biology, in particular in the field of developmental and regenerative biology. The invention generally...
2018/0155685 METHOD FOR INDUCING OLIGODENDROCYTE PRECURSOR CELLS FROM OCT4-INDUCED HUMAN SOMATIC CELLS THROUGH DIRECT...
Provided is a method of inducing oligodendrocyte precursor cells (OPCS) through direct reprogramming from human somatic cells into which a nucleic acid...
2018/0155684 Neural Progenitor Cell Differentiation
Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ECM) compositions,...
2018/0155683 Methods and Compositions for Somatic Cell Proliferation and Viability
Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding...
2018/0155682 METHOD FOR INDUCING DIFFERENTIATION OF NEURAL CREST CELLS INTO NEURONS OF THE AUTONOMIC NERVOUS SYSTEM
Provided is a method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system, the method including the step of...
2018/0155681 MESODERM AND DEFINITIVE ENDODERM CELL POPULATIONS
The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell...
2018/0155679 CELL CULTURING METHOD AND KIT
The present invention relates to a cell culturing method and kit. More specifically, it relates to a cell culturing method and kit using a support that is...
2018/0155678 PLACENTA-DERIVED MATRIX AND METHODS OF PREPARING AND USE THEREOF
The invention relates to placenta-derived matrix, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells,...
2018/0155677 METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION
The invention provides methods and compositions for preparing antibodies and antibody derivatives with reduced core fucosylation.
2018/0155676 CELL CULTURING METHOD USING NUCLEIC ACID-CONTAINING MEDIUM
An object of the present invention is to provide an animal cell culture method which is high in protein productivity. Provided is a method for culturing animal...
2018/0155675 Method for Dedifferentiating and Culturing Microbial Species
Methods and devices useful for reprogramming microbial cells to grow under different culture conditions are provided. The methods and devices can be used to...
2018/0155674 YEAST STRAIN HAVING IMPROVED CAPABILITY FOR FERMENTING XYLOSE IN THE PRESENCE OF ACETIC ACID
The invention relates to a method for selecting a yeast strain having improved capability for fermenting a pentose, advantageously xylose, in the presence of...
2018/0155673 METHOD FOR CULTURING ANIMAL CELL COMPOSITION, METHOD FOR PRODUCING ANIMAL CELL COMPOSITION USING SAME, AND...
An object of the present invention is to obtain a thicker animal cell composition by a simple and less expensive method. Namely, an object of the present...
2018/0155672 METHOD FOR DEVELOPING MALARIA SPOROZOITES IN VITRO
Described in this application is a method for producing Plasmodium sporozoites in a cell-free, mosquito-free in vitro culture-system. Compositions and methods...
2018/0155671 AIRCRAFT FUEL TANK WITH A VISUAL CONTROL SYSTEM INSIDE THE TANK, RELATED AIRCRAFT AND VISUAL CONTROL METHOD
Aircraft fuel tank, which has a visual control system inside the tank, includes at least a side wall (12), an upper wall (14) and a lower wall (16), the tank...
2018/0155670 MICROBIAL EXPERIMENT COOLING AND TEMPERATURE-SENSING MULTIPURPOSE RACK
A multi-function cooling and thermo-sensitive rack includes horizontal bars, a base, positioning holes, connectors, a lateral frame, connecting holes, a...
2018/0155669 Device for Mechanical and Hydrodynamic Microfluidic Transfection
Methods for introducing exogenous material into a cell are provided, which include exposing the cell to a transient decrease in pressure in the presence of the...
2018/0155668 BIOMANUFACTURING SUITE AND METHODS FOR LARGE-SCALE PRODUCTION OF CELLS, VIRUSES, AND BIOMOLECULES
The present invention provides a production module for large-scale production of cells and/or cell-derived products such as antibodies or virus; a production...
2018/0155667 RETENTION SYSTEM
The present invention relates to a Disposable Bioprocess System consisting of a Single-Use-Bioreactor, a Single-Use-Pump and a single-use micro-organism...
2018/0155666 Low Surface Energy Coatings For Mammalian Cell Culture
A cultureware system is directed to maintaining viability of mammalian cells, and includes a disposable holding container having a cell receiver with a...
2018/0155665 CELL CULTURE APPARATUS AND CULTURE METHODS USING SAME
Cell culture apparatus for emulating gastrointestinal tract conditions and comprising at least two adjacent, microfluidic, cell cultivation channels separated...
2018/0155664 MULTI-MICROWELL ARRAY FOR MULTI-CELLULAR ADJACENT CO-CULTURE
The invention provides a multi-microwell platform that enables co-culture of up to 4 cell types in discrete adjacent wells using either 2-dimension or...
2018/0155663 PRESSURIZED BEVERAGE CONCENTRATES AND APPLIANCES AND METHODS FOR PRODUCING BEVERAGES THEREFROM
The present invention describes methods and devices in which concentrated beverage products, each packaged in a pressurized container, can be combined with...
2018/0155662 PRESSURIZED BEVERAGE CONCENTRATES AND APPLIANCES AND METHODS FOR PRODUCING BEVERAGES THEREFROM
The present invention describes methods and devices in which concentrated beverage products, each packaged in a pressurized container, can be combined with...
2018/0155661 Water-Soluble Encapsulated PH Control Agent
The present invention is directed to materials and method of encapsulating chemical agents. In particular, the present invention is directed to compositions...
2018/0155660 TOILET RIM BLOCK AND RIM BLOCK CAGE
A toilet rim block which consists of an outer cover and a core, and to a rim block cage including the toilet rim block. The outer cover includes a first...
2018/0155659 STORAGE STABLE LIQUID WASHING OR CLEANING AGENT CONTAINING PROTEASE AND CELLULASE
According to the invention, storage stability in terms of cellulolytic activity is to be improved in a liquid washing or cleaning agent which comprises a...
2018/0155658 CLEANING COMPOSITIONS INCLUDING ENZYME AND BLEACH
Cleaning compositions that include an extracellular-polymer-degrading enzyme selected from the group consisting of endo-beta-1,6-galactanase enzymes, mannanase...
2018/0155657 LAUNDRY DETERGENT COMPOSITION
The present invention provides a domestic laundry cleaning composition, said composition comprising an anionic surfactant, an alkyl ether carboxylic acid...
2018/0155656 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS
A laundry care composition including at least one laundry care ingredient and at least one leuco polymer including a polymeric carbohydrate and a leuco moiety....
2018/0155655 COMPOSITION
A dishwasher detergent composition, preferably pH neutral, and comprising a strong biodegradable builder and optionally a bleach, and optionally a sulfonated...
2018/0155654 ANIONIC SURFACTANTS AND DETERGENTS COMPRISING THEM
Surfactants of the general formula (I) in which R.sup.1 is a linear or branched akyl radical having 6 to 20, especially 10 to 16 C atoms, R.sup.2 and R.sup.3...
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