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Patent # Description
2018/0162974 FLUORINATED POLYMER, METHOD FOR ITS PRODUCTION, AND CURED PRODUCT OF THE FLUORINATED POLYMER
To provide a curable fluorinated polymer excellent in solubility in an alcohol, a method for its production and a cured product of the fluorinated polymer. A...
2018/0162973 Production of Polyolefins with Internal Unsaturation Structures Using a Metallocene Catalyst System
This invention relates to a process to polymerize olefins, particularly to produce ethylene polymers with internal unsaturation structures.
2018/0162972 MICROSTRUCTURE-CONTROLLED COPOLYMERS OF ETHYLENE AND C3-C10 ALPHA-OLEFINS
A copolymer including ethylene units and units of one or more C.sub.3-10 alpha-olefins. The copolymer has a number average molecular weight of less than 5,000...
2018/0162971 Thermoplastic Polyolefin Compositions
This invention relates to a thermoplastic polyolefin composition with (a) a polypropylene having a melting point of greater than 130.degree. C. and a melt flow...
2018/0162970 Ziegler-Natta - Metallocene Dual Catalyst Systems with Activator-Supports
Catalyst systems having both a metallocene catalyst component and a Ziegler-Natta component are disclosed. Such catalyst systems can contain a metallocene...
2018/0162969 Process for Transitioning Between Low Percentage Chrome and High Percentage Chrome Catalysts
A method of transitioning from a first catalyst to a second catalyst in a gas phase fluidized bed reactor comprising continuously feeding the first catalyst...
2018/0162968 POLYARYLENE RESINS
Certain cyclopentadienone monomers having polar moieties are useful in forming polyarylene resins having improved solubility in certain organic solvents and...
2018/0162967 POLYARYLENE RESIN COMPOSITIONS
Polyarylene oligomer compositions capable of curing at lower temperatures than conventional polyarylene oligomers are useful in forming dielectric material...
2018/0162966 METHOD FOR PRODUCING POLYACRYLAMIDE COMPOSITION
Disclosed is a method for producing an aldehyde crosslinked polyacrylamide composition useful for strengthening paper. The method includes steps, wherein a) an...
2018/0162965 PROCESS FOR MANUFACTURING A DISPERSION OF A VINYLIDENE FLUORIDE POLYMER
A process for manufacturing a dispersion of a vinylidene fluoride (VDF) thermoplastic polymer [polymer (F)], said process includes polymerizing VDF in an...
2018/0162964 Supported Metallocene Catalyst Systems for Polymerization
This invention relates to supported metallocene catalyst systems for polymerization, the catalyst systems comprising asymmetrically substituted indenyl groups,...
2018/0162963 POLYMERIC BINDERS FOR INK JET INKS
A process for improving a latex comprising the steps of (a) providing a latex comprising a polymer binder, wherein said polymer binder is formed by...
2018/0162962 Recovery of Unreacted Monomers from Olefin Polymerization Processes
A process, for recovery of unreacted olefin monomer(s) from a particulate product of an olefin polymerization reactor, the particulate polymer product is...
2018/0162961 Methods to Control Swell Index in High Impact Polystyrene
A method including operating a high impact polystyrene (HIPS) reaction system having a devolatilizer downstream of a polymerization reactor, and from which a...
2018/0162960 MODIFIED PLANT FIBERS, ADDITIVE FOR RUBBER, PROCESS FOR PRODUCING SAME, AND RUBBER COMPOSITION
Provided are modified plant fibers suitable for addition to rubber; an additive for rubber comprising the modified plant fibers which can be micronized and...
2018/0162959 MODIFIED AND CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THEREOF
The present invention provides a compound represented by Formula 1, a modified and conjugated diene-based polymer with a high modification ratio, which...
2018/0162958 METHODS FOR TREATING LIGNOCELLULOSIC MATERIALS
Methods for producing refined xylan from a biomass solution, including: (i) providing a biomass solution, which comprises xylan; (ii) concentrating or...
2018/0162957 PROCESS FOR PREPARING (1→6)-α-D-GLUCAN
A process for preparing (1.fwdarw.6)-.alpha.-D-glucan. A large amount of (1.fwdarw.6)-.alpha.-D-glucan can be prepared from banana by using this process. The...
2018/0162956 WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF
The presently disclosed subject matter provides nitric oxide-releasing polysaccharides and oligosaccharides, in particular, polyglucosamines, and their use in...
2018/0162955 ASSEMBLY OF BISPECIFIC ANTIBODIES
Described herein are methods for the efficient production of a heteromultimeric protein, such as a bispecific antibody. Heteromultimeric proteins may be...
2018/0162954 METHODS FOR INCREASING THERMOGENIC ADIPOCYTES
In certain aspects, the present invention provides compositions and methods for increasing thermogenic adipocytes (e.g., brown adipocytes or other UCP-1...
2018/0162953 ASSAYS FOR TIMP2 HAVING IMPROVED PERFORMANCE IN BIOLOGICAL SAMPLES
The invention provides TIMP2 immunoassays with improved clinical performance, particularly when used in the evaluation of renal injuries. The immunoassays rely...
2018/0162952 NOVEL MODULATORS AND METHODS OF USE
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyperproliferative disorders are provided.
2018/0162951 TREATMENT WITH ANTI-ErbB2 ANTIBODIES
The present invention concerns the treatment of cancer with anti-ErbB2 antibodies.
2018/0162950 Fc VARIANTS WITH ALTERED BINDING TO FcRn
The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for...
2018/0162949 PSMA Targeting Trispecific Proteins and Methods of Use
Provided herein are prostate specific membrane antigen (PSMA) targeting trispecific proteins comprising a domain binding to CD3, a half-life extension domain,...
2018/0162948 CD138-TARGETED INTERFERON DEMONSTRATES POTENT APOPTOTIC AND ANTI-TUMOR ACTIVITIES
In various embodiments chimeric moieties (constructs) are provided that show significant efficacy against cancers. In certain embodiments the constructs...
2018/0162947 ANTIBODIES
The present invention relates to an anti-CSF-1R antibody and binding fragments thereof, DNA encoding the same, host cells comprising said DNA and methods of...
2018/0162946 Fc VARIANTS WITH ALTERED BINDING TO FcRn
The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for...
2018/0162945 SUBCUTANEOUS ANTI-HLA-DR MONOCLONAL ANTIBODY FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES
The present invention concerns compositions and methods of use of anti-HLA-DR antibodies or fragments thereof. In preferred embodiments, the antibodies are...
2018/0162944 NOVEL ANTI-PD-L1 ANTIBODIES
The present disclosure provides monoclonal antibodies against protein programmed cell death 1 ligand (PD-L1), which can block the binding of PD-L1 to PD-1, and...
2018/0162943 GM-CSF/CD40L VACCINE AND CHECKPOINT INHIBITOR COMBINATION THERAPY
A method is disclosed for treating a cancer in a subject. The method comprises administering to the subject a composition comprising a therapeutically...
2018/0162942 TREATMENT OF RENAL CELL CARCINOMA
This disclosure provides methods for treating a subject afflicted with a tumor derived from a renal cell carcinoma. The methods comprise administering a first...
2018/0162941 COMBINATION THERAPY FOR HEPATOCELLULAR CARCINOMA
Provided are methods and compositions for a combination therapy for liver disorders such as hepatocellular carcinoma. Also provided is a method for determining...
2018/0162940 ANTI-CEACAM6 ANTIBODIES AND USES THEREOF
The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are...
2018/0162939 CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF
The present disclosure provides chimeric antigen receptors, compostions, and methods thereof. In one embodiment the present disclosure provides a method of...
2018/0162938 ANTIBODIES SPECIFIC FOR CLAUDIN 6 (CLDN6)
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing Claudin-6 (CLDN6),...
2018/0162937 ANTI-5T4 ANTIBODIES AND USES THEREOF
Anti-5T4 antibodies, anti-5T4 antibody/drug conjugates, and methods for preparing and using the same.
2018/0162936 Compounds
Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6 ) and neutralise its biological effects. Use of binding members for IL-6 in...
2018/0162935 PRECISION MEDICINE FOR CHOLESTEROL TREATMENT
The invention relates to human targets of interest (TOI), anti-TOI ligands, kits compositions and method.
2018/0162934 COMPOSITIONS AND METHODS RELATING TO INHIBITING CANCER CELL GROWTH AND/OR PROLIFERATION
The present invention determined that EGFL6 functions as a tumor vascular regulator of ovarian cancer stem cells (CSC). In addition, the present invention...
2018/0162933 ANTIBODIES AGAINST THE RGM A PROTEIN AND USES THEREOF
The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize RGM A protein. Specifically, these antibodies...
2018/0162932 ANTIBODIES BINDING TO BMP4, AND USES THEREOF
The present invention relates to antibody which binds to an epitope located within the BMPR1 binding region of BMP4.
2018/0162931 METHODS FOR TREATING HEADACHE USING ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE
The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster...
2018/0162930 IMMUNOGLOBULIN PURIFICATION
The current invention reports a method for purifying an immunoglobulin, wherein the method comprises applying an aqueous, buffered solution comprising an...
2018/0162929 CD137 Binding Fibronectin Type III Domains
FN3 domains that specifically bind to CD137, their conjugates, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making and...
2018/0162928 PD-L1 Binding Fibronectin Type III Domains
FN3 domains that specifically bind to PD-L1, their conjugates, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making and...
2018/0162927 CD8A-Binding Fibronectin Type III Domains
Fibronectin type III domains (FN3) that specifically bind to CD8A, related polynucleotides capable of encoding CD8A-specific FN3 domains, cells expressing the...
2018/0162926 INHIBITORS OF TYPE 2 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to...
2018/0162925 ALBUMIN VARIANTS
The present invention relates to variants of a parent albumin having altered plasma half-life compared with the parent albumin. The present invention also...
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