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Patent # Description
2018/0162823 PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS
The present invention provides compounds of Formula (I): ##STR00001## or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the...
2018/0162822 HETEROCYCLIC INHIBITORS OF MCT4
Disclosed herein are compounds and compositions useful in the treatment of MCT4 mediated diseases, such as proliferative and inflammatory diseases, having the...
2018/0162821 FACTOR XIA MACROCYCLES WITH NOVEL P1 GROUPS
The present invention provides compounds of Formula (I): P-Ma (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the...
2018/0162820 NEW METHOD FOR THE PREPARATION OF HIGHLY PURE IVABRADINE BASE AND SALTS THEREOF
A method for the preparation of purified ivabradine and salts thereof, a method for the purification of ivabradine and salts thereof, a new reactant used in...
2018/0162819 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM
The present invention relates to methods and compounds for regulating or enhancing erythropoiesis and iron metabolism, and for treating or preventing iron...
2018/0162818 211-ASTATINE CONTAINING RADIOTHERAPEUTICS FOR THE TREATMENT OF CANCER
Described herein is an alpha-emitting radionuclide, .sup.211At, which has been incorporated into a selective sigma-2 ligand moiety to provide cytotoxic...
2018/0162817 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES
The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for...
2018/0162816 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS
Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety...
2018/0162815 ROR GAMMA (RORY) MODULATORS
Novel compounds according to Formula I ##STR00001## or a pharmaceutically acceptable salt thereof wherein: A.sub.11-A.sub.14 are N or CR.sub.11, CR.sub.12,...
2018/0162814 METHOD OF PREPARING BENZYL 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PICOLINATE
A method of preparing benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (I) from benzyl ...
2018/0162813 MIF MODULATORS
The invention provides novel heterocyclic compounds, pharmaceutical compositions and methods of treatment that modulate levels of MIF expression and treat...
2018/0162812 COVALENT INHIBITORS OF KRAS G12C
Irreversible inhibitors of G12C mutant K-Ras protein are provided. Also disclosed are methods to modulate the activity of G12C mutant K-Ras protein and methods...
2018/0162811 ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING ISOTHIOCYANATE FUNCTIONAL SURFACTANTS AND...
The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate...
2018/0162810 MANUFACTURE OF ORGANOPOLYSULFIDES AND SALTS THEREOF
A method of producing an organopolysulfide or salt thereof is provided which includes a step of mixing an organomonosulfide or salt thereof and elemental...
2018/0162809 ROR GAMMA (RORY) MODULATORS
The present invention relates to compounds according to Formula I: or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of...
2018/0162808 ROR GAMMA (RORy) MODULATORS
The present application relates to compounds according to (Formula IA) or (Formula IB): ##STR00001## or a pharmaceutically acceptable salt thereof. The...
2018/0162807 AROMATIC COMPOUNDS AND USES THEREOF
Aromatic entities that modulate HIF-2.alpha. activity, pharmaceutical compositions containing the aromatic entities, and methods of using these chemical...
2018/0162806 PROCESS FOR PRODUCING TAURINE
There is disclosed a process for producing taurine by decomposing ammonium taurinate to taurine and ammonia. Ammonium taurinate is prepared by the...
2018/0162805 METHOD FOR PREPARING CITALOPRAM DIOL INTERMEDIATE
The present invention relates to a method for preparing a citalopram diol represented by formula IV, comprising the following steps: in the existence of an...
2018/0162804 PENDANT AMINES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
This present disclosure is directed to compounds of formula (I): ##STR00001## where R.sup.1a, R.sup.1b, R.sup.1c, R.sup.1d, R.sup.1e, R.sup.3, R.sup.4a,...
2018/0162803 METAL COMPLEXES
The disclosure provides metal complexes which have improved stability in the presence of humidity. The disclosure also provides a method of making metal...
2018/0162802 MONAMINE AND MONOAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
This present disclosure is directed to compounds of formula (I): ##STR00001## where r, q, R.sup.1a, R.sup.1b, R.sup.1c, R.sup.1d, R.sup.1e, R.sup.2, R.sup.3,...
2018/0162801 METHODS OF MAKING CERIUM OXIDE POLYANILINE COMPOSITE NANOSPHERES AND METHODS OF USE
Methods of synthesizing cerium oxide and polyaniline nanocomposites, including nanospheres enclosing a hollow core, are specified. Properties of the cerium...
2018/0162800 Use of the Irritating Principal Oleocanthal in Olive Oil, as Well as Structurally and Functionally Similar...
The invention provides methods of synthesizing the purified enantiomers of oleocanthal. The invention further provides methods of using oleocanthals in various...
2018/0162799 SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF
The present invention relates to substituted aromatic compounds of Formula I and their pharmaceutical uses. Particular aspects of the invention relate to the...
2018/0162798 METHOD FOR THE PRODUCTION OF 2,4-DIHYDROXYBUTYRIC ACID
Methods for the production of 2,4-dihydroxybutyrate (2,4-DHB) from erythrose and other four-carbon sugars are disclosed. The improved methods facilitate the...
2018/0162797 SEPARATION OF ORGANIC ACIDS FROM MIXTURES CONTAINING AMMONIUM SALTS OF ORGANIC ACIDS
The invention relates to a process for separation of organic acids from mixture of ammonium salts of one or more organic acids and other compounds via an...
2018/0162796 METHOD FOR PREPARING BRANCHED ALCOHOL
A method for preparing a branched alcohol by dimerizing an aliphatic monoalcohol having three or more carbon atoms in the presence of a base and a catalyst....
2018/0162795 METHOD FOR PRODUCING FLUORINATED OLEFINS
Fluorinated olefins are produced in a reductive coupling reaction by contacting a first reactant with a second reactant in the gas phase under an inert...
2018/0162794 METHOD OF MANUFACTURING 1-CHLORO-2,3,3-TRIFLUOROPROPENE
There is provided a method of efficiently manufacturing 1-chloro-2,3,3-trifluoropropene by an industrially feasible method by using a raw material which is...
2018/0162793 PROCESSES FOR THE SYNTHESIS OF 1,2,3,4-TETRACHLORO-HEXAFLUORO-BUTANE
The present invention relates to processes for the manufacture of 1,2,3,4-tetrachloro-hexafluoro-butane in a microreactor.
2018/0162792 PREPARATION OF ALKYLAROMATIC COMPOUNDS
Described herein are methods useful for preparing alkylaromatics.
2018/0162791 DEHYDROGENATION OF OLEFIN-RICH HYDROCARBON MIXTURES
The object of the invention is to specify a process for dehydrogenating alkanes in which such feedstock mixtures may be used having a high proportion of...
2018/0162790 MODIFIED PROPANE DEHYDROGENATION SYSTEM AND METHOD FOR PRODUCING ONE OR MORE CHEMICAL PRODUCTS FROM PROPANE
Disclosed is a modified propene dehydrogenation (PDH) system and method for producing one or more chemical products from propane as the sole feed stock. The...
2018/0162789 METHODS AND SYSTEMS FOR CONVERTING HYDROCARBONS
Methods and systems for converting hydrocarbons including exposing a portion of a hydroperoxide-containing feed including tert-butyl hydroperoxide to a solid...
2018/0162788 PRODUCTION OF ISO-OCTENE FROM TERTIARY ALCOHOLS
Systems and methods are provided for forming alkylate from a tertiary alcohol feed. Olefins for the alkylation reaction can be generated from a portion of the...
2018/0162787 PRODUCTION OF HIGH OCTANE HYDROCARBON FROM LIGHT ALKANE FEED USING OXIDATION AND ACID CATALYSIS CHEMISTRY
Systems and methods are provided for production of high octane hydrocarbon from an isoparaffin feed using oxidation acid catalysis chemistry.
2018/0162786 PRODUCTION OF ALKYLATE FROM LIGHT ALKANES
Systems and methods are provided for forming alkylate from an isoparaffin-containing feed. Olefins for the alkylation reaction can be generated from a portion...
2018/0162785 LOW INLET TEMPERATURE FOR OXIDATIVE COUPLING OF METHANE
Disclosed is a process for producing C.sub.2+ hydrocarbons, and systems for implementing the process, that includes providing a reactant feed that includes...
2018/0162784 CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING
Conjugates derived from non-steroidal anti-inflammatory drugs (NSAIDs) and methods of use thereof are disclosed, useful for, inter alia, identifying and...
2018/0162783 Non-Aqueous Organo Liquid Delivery Systems containing dispersed Poly (organic acids) that improve availability...
The present invention relates to improving the efficiency of man-made and/or natural organic-based animal manure fertilizers by administration of formulations...
2018/0162782 EFFICIENCY OF MAN-MADE AND/OR NATURAL ORGANIC BASED ANIMAL MANURE FERTILIZERS BY LIBERATING THE BOUND NUTRIENTS...
The present invention relates to improving the efficacy of man-made and/or natural organic-based animal manure fertilizers by administration of an organic...
2018/0162781 FERTILIZER PELLETS WITH MICRONIZED SULPHUR
Fertilizer pellets may be formed by compressing or compacting a primary fertilizer powder mixed with micronized sulphur.
2018/0162780 MULTILAYER CERAMIC CAPACITOR AND MANUFACTURING METHOD OF MULTILAYER CERAMIC CAPACITOR
A multilayer ceramic capacitor includes: a multilayer chip in which each of dielectric layers and each of internal electrode layers are alternately stacked and...
2018/0162779 CUTTING TOOL INSERT
A polycrystalline diamond (PCD) compact and method for making the compact are provided. The method includes bringing a first PCD wafer and a second PCD wafer...
2018/0162778 REFRACTORIES FOR APPLICATIONS IN COMBUSTION CHAMBERS INTENDED FOR PRODUCING ENERGY AND/OR WASTE DISPOSAL
The present invention relates to refractories with a composition gradient for lining the interior surface of combustion chambers. The invention envisages the...
2018/0162777 SELF-DESICCATING, DIMENSIONALLY-STABLE HYDRAULIC CEMENT COMPOSITIONS WITH ENHANCED WORKABILITY
Cementitious binder compositions for cementitious products including a hydraulic cement-based reactive powder blend, an inorganic flow control agent, and a...
2018/0162776 Self-Consolidating Concrete Construction with Self-Roughening Properties
Adding a small amount of lightweight course aggregate to a normal weight concrete mix to produce a clean, rough top surface so that manual or mechanical...
2018/0162775 DISPERSANT COMPOSITION FOR HYDRAULIC COMPOSITIONS FOR CENTRIFUGAL MOLDING
The present invention provides a dispersant composition for hydraulic compositions for centrifugal molding, which contains (A) a dispersant for hydraulic...
2018/0162774 METHOD TO PRODUCE AGGREGATES FROM UNSETTLED CEMENTITIOUS MIXTURES
Method to produce aggregates from unsettled cementitious mixtures, comprising the steps of (a) adding at least one pelletizing agent to an unsettled...
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