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Patent # Description
2018/0161404 CONTROLLED RELEASE SYSTEM FOR PULMONARY DELIVERY OF SURFACTANT PROTEIN D
A controlled release system includes surfactant protein D (SPD) and a carrier suitable for controlled release that can be polylactic-co-glycolic acid (PLGA)....
2018/0161403 ADENO-ASSOCIATED VIRUS FACTOR VIII VECTORS
The invention provides improved adeno-associated virus (AAV) Factor VIII (FVIII) vectors, including AAV FVIII vectors that produce a functional Factor VIII...
2018/0161402 TRUNCATED VON WILLEBRAND FACTOR POLYPEPTIDES FOR TREATING HEMOPHILIA
The invention relates to a polypeptide comprising a truncated von Willebrand Factor (VWF) for use in the treatment of a blood coagulation disorder, wherein the...
2018/0161401 Novel Formulations of PTHrP Analogue
The present invention provides a non-buffered, neutral pH easily prepared, storage-stable composition containing a parathyroid hormone-related protein (PTHrP)...
2018/0161400 ANTIDIABETIC ORAL INSULIN BIGUANIDE COMBINATION
Pharmaceutical dosage forms, comprising insulin, a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream...
2018/0161399 TREATMENT OF CANCER WITH IMMUNE STIMULATORS
The present invention provides compositions and methods for treating cancer or a metastasis thereof in a subject. In some embodiments, the methods involve...
2018/0161398 COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK
The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing...
2018/0161397 METHODS FOR MODULATING AN INFLAMMATORY RESPONSE
The inventive subject matter relates to novel methods for modulating an immune response in an animal, which comprises administering to said animal an effective...
2018/0161396 NOVEL T CELL RECEPTORS AND IMMUNE THERAPY USING THE SAME
The present invention pertains to antigen recognizing constructs against tumor associated antigens (MAGEA1). The invention in particular provides novel T cell...
2018/0161395 METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALZHEIMER'S DISEASE
The present invention relates to methods and pharmaceutical compositions for the treatment of Alzheimer's disease. In particular the present invention relates...
2018/0161394 Methods and Related Kits for Treating and Regenerating Tooth Pulp and Periapical Tissues in a Mammal
In one embodiment, a method of regenerating tooth pulp in a mammal is provided. The method comprises removing at least a portion the existing tooth pulp of a...
2018/0161393 PRG4 FOR TREATING GOUT AND ITS SYMPTOMS
Disclosed are methods of treating gout in a subject and methods of reducing joint pain in a subject with gout or pseudogout, comprising administering to the...
2018/0161392 THERAPEUTIC USE OF P75NTR NEUROTROPHIN BINDING PROTEIN
The present invention relates to a p75NTR neurotrophin binding protein, p75NTR(NBP), for use in the treatment of pain and/or a symptom of pain.
2018/0161391 INHIBITORS OF BCL-2
A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids...
2018/0161390 ADIPONECTIN PEPTIDOMIMETICS FOR TREATING OCULAR DISORDERS
Provided herein are compositions and methods for treating dry eye or an ocular disease associated with inflammation in a subject in need thereof. The...
2018/0161389 R-SPONDIN AGONIST-MEDIATED HAIR GROWTH
Cosmetic skin and hair care compositions for enhancing the growth and appearance of mammalian hair in an individual are provided, which compositions comprise a...
2018/0161388 SUBSTANCE P, MAST CELL DEGRANULATION INHIBITORS, AND PERIPHERAL NEUROPATHY
Described herein are methods of using Substance P, mast cell degranulation inhibitors, or combinations thereof to delay the onset of, to reverse, or to reduce...
2018/0161387 COMPOSITIONS OF HERBAL FORMULATIONS AND USES THEREOF
Disclosed herein are herbal formulations for relief from symptoms of skin disease. The formulations can also be combined with an active or inactive ...
2018/0161386 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DEPRESSION AND PREPARATION METHOD THEREOF
Disclosed is a pharmaceutical composition for the treatment of Depression, wherein the pharmaceutical composition is comprised of the following herbs in weight...
2018/0161385 COMPOSITIONS AND METHODS FOR MAINTAINING OR ENHANCING HOMEOSTASIS OR FUNCTION OF FEMALE LOWER REPRODUCTIVE TRACT
The present disclosure provides compositions and methods for making and using topical compositions comprised of an isotonic, biome-friendly solution containing...
2018/0161384 Vaporized Medicants and Methods of Use
A method and formulation for delivering an active analgesic compound, such as an opiate, in a vaporized state using low temperatures to vaporize the...
2018/0161383 NATURAL PHARMACEUTICAL COMPOSITION FOR TREATING MENOPAUSAL MENTAL DEPRESSION AND ATYPICAL DEPRESSIVE DISORDER...
The present disclosure discloses a pharmaceutical composition for treating menopausal mental depression and atypical depressive disorder and an application...
2018/0161382 PREBIOTIC COMPOSITIONS COMPRISING ONE OR MORE TYPES OF BACTERIOPHAGE
Disclosed herein are compositions that comprise one or more types of bacteriophage and methods of using such bacteriophages as a prebiotic to promote the...
2018/0161381 NUTRITIONAL COMPOSITIONS AND METHODS FOR REDUCING THE OCCURRENCE OR SEVERITY OF VIRAL INFECTIONS, BACTERIAL...
The present disclosure is directed to methods for reducing the risk of developing or reducing the severity of a viral infection, bacterial infection, or viral...
2018/0161380 THERAPEUTIC TREATMENT OF SKIN DISEASE WITH RECOMBINANT COMMENSAL SKIN MICROORGANISMS
The invention relates to methods for treating or preventing abnormal skin conditions in a human in need thereof, comprising administering a cell culture...
2018/0161379 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING TISSUE INJURY AND DISEASE
The present invention provides novel compositions comprising multipotent cells or microvascular tissue, wherein the cells or tissue has been sterilized and/or...
2018/0161378 AGENT FOR PROMOTING MIGRATION OF PLURIPOTENT STEM CELLS
An agent for promoting migration of pluripotent stem cells containing an extract from inflamed tissues inoculated with vaccinia virus. An extract from inflamed...
2018/0161377 METHOD OF TREATING NEUROLOGICAL DISORDERS WITH STEM CELL THERAPY
A method for isolating self-renewable stem cells from pluripotent stem cells (embryonic or induced) by treating the pluripotent stem cells with a combination...
2018/0161376 COMPOSITIONS AND METHODS FOR NEURONAL DIFFERENTIATION OF CELLS
This invention relates to compositions and methods for enhanced differentiation of cells towards a neuronal phenotype. Neuronal cells produced using the...
2018/0161375 Therapeutic method for repairing damaged pancreas
The invention is a therapeutic method for repairing damaged pancreas. The method comprises administrating Epigallocatechin gallate (EGCG) of green tea and a...
2018/0161374 USING AUTOLOGOUS MESENCHYMAL STEM CELLS TO TREAT MULTIPLE SYSTEM ATROPHY
This document provides methods and materials for treating multiple system atrophy in a mammal. Specifically, the methods comprises intrathecally administering...
2018/0161373 METHODS AND DEVICES FOR THE PRODUCTION AND DELIVERY OF BENEFICIAL FACTORS FROM STEM CELLS
Provided herein are methods and devices related to inducing a population of self-renewing or senescent stem cells, to produce one or more beneficial factors...
2018/0161371 ENGINEERED NATURAL KILLER CELLS AND USES THEREOF
Disclosed herein are engineered natural killer cells that have been modified to express chimeric antigen receptors (CARs). The cells optionally contain other...
2018/0161370 METHODS FOR EXPANSION OR DEPLETION OF T-REGULATORY CELLS
The invention features methods of producing compositions enriched in Tregs and methods for treating immunological disorders using these compositions. The...
2018/0161369 COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY
The present disclosure relates to compositions and methods for using cells having cellular immunotherapies comprising a composition of chimeric antigen...
2018/0161368 COMPOSITION AND METHODS FOR REGULATING INHIBITORY INTERACTIONS IN GENETICALLY ENGINEERED CELLS
Provided are engineered cells for adoptive therapy, including T cells. Also provided are methods and compositions for engineering and producing the cells,...
2018/0161367 THERAPY AND METHODS FOR INTRODUCING IMMATURE AND DENDRITIC CELLS AND/OR CYTOTOXIC T LYMPHOCYTE AND ANTI-TNF...
The invention relates to therapy and methods of applying the therapy to a patient. The invention includes the introduction of immature dendritic cells into the...
2018/0161366 METHODS OF OBTAINING MONONUCLEAR BLOOD CELLS AND USES THEREOF
Methods of obtaining mononuclear blood cells are provided. Also provided are methods of using the obtained cells for treating diseases such as cancer,...
2018/0161365 Phosphate-Binding Magnesium Salts And Uses Thereof
The present invention provides, among other things, compositions and methods suitable for the treatment of hyperphosphatemia based on phosphate-binding...
2018/0161364 CATIONIC COMPOUNDS AND THEIR USE AS ANTIMYCOTIC AND ANTIMICROBIAL AGENTS
The invention relates to cationic compounds and their use as antimicrobial and antimycotic agents, in particular as disinfectants and preservatives in...
2018/0161363 Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications
The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces....
2018/0161362 Controllably Degradable Compositions and Methods
Methods for treating, adhering, or sealing biological tissue are provided. The methods include combining solutions containing a polymer component and a...
2018/0161361 USE OF A BLOCK POLYMER COMPRISING A BLOCK OF POLY(3-(METHACRYLOYLAMINO)PROPYLTRIMETHYLAMMONIUM CHLORIDE)...
The subject of the invention is use of block polymers with a block of poly(3-methacryloylpropyltrimethylammonium chloride) to direct neutralization of heparin,...
2018/0161360 P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION
Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided...
2018/0161359 METHODS AND COMPOUNDS FOR TREATMENT OF LYMPHOCYTE-RELATED DISEASES AND CONDITIONS
Methods for treatment of lymphocyte-related diseases and conditions, such as cancer and automimmune diseases, are provided. The methods comprise administration...
2018/0161358 COMPOSITIONS AND METHODS FOR TREATING CANCER
Provided are nucleic acid constructs and systems which comprise (i) a first nucleic acid construct encoding a toxin operatively linked to a first promoter and...
2018/0161357 MIR-155 INHIBITORS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS (ALS)
The present invention provides methods for treating a neurological disease such as ALS in a subject by administering to the subject an oligonucleotide...
2018/0161355 Method For Storing P1, P4-bis(5'-Uridyl)Tetraphosphate Crystals
[Problem] Provided is a method for easily and stably storing crystals of P.sup.1, P.sup.4-bis(5'-uridyl)tetraphosphate for a long term. [Solution] A method for...
2018/0161354 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
2018/0161353 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
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