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Patent # Description
2018/0161352 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
2018/0161351 NUTRITIONAL FORMULATIONS INCLUDING HUMAN MILK OLIGOSACCHARIDES AND ANTIOXIDANTS AND USES THEREOF
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that...
2018/0161350 TERNARY MIXTURES OF 6'-SL, LNnT and LST c
A mixture of human milk oligosaccharides that consists essentially of 6'-SL, LNnT and LSTc, made by treating 6'-SL and LNnT in the presence of an...
2018/0161349 ARGINASE INHIBITOR COMBINATION THERAPIES
The disclosure relates to methods of treating or preventing a disease in a subject by conjointly administering to the subject an arginase inhibitor disclosed...
2018/0161348 OSTEOCLAST INHIBITORS SUCH AS ZOLEDRONIC ACID FOR LOW BACK PAIN TREATMENT
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2018/0161347 METHODS AND MATERIALS FOR KILLING HIV INFECTED CELLS
This document provides methods and materials involved in killing HIV infected cells (e.g., CD4 T cells). For example, methods and materials for using one or...
2018/0161346 ESTRIOL THERAPY FOR TREATMENT OF MULTIPLE SCLEROSIS
The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, including post-partum auto immune diseases....
2018/0161345 VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
In one aspect, pharmaceutical compositions and methods for the treatment of vulvovaginal atrophy (VVA) are provided. In one embodiment, the method comprises...
2018/0161344 VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
In one aspect, compositions and methods for the treatment of vulvovaginal atrophy (VVA) are provided. In one embodiment, the method comprises administering an...
2018/0161343 VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
In one aspect, compositions and methods for the treatment of vulvovaginal atrophy (VVA) are provided. In one embodiment, the method comprises administering an...
2018/0161341 USE OF N-DESMETHYLCLOBAZAM IN THE TREATMENT OF CHRONIC PAIN DISORDERS AND RELATED METHODS
The present invention is directed to N-desmethylclobazam or any suitable pharmaceutically acceptable thereof useful for the prevention and/or treatment of a...
2018/0161340 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS
In one aspect, pharmaceutical compositions comprising a CDK2 inhibitor and one or more of at least one agent known to treat a hearing impairment and at least...
2018/0161339 USE OF CARBONIC ANHYDRASE INHIBITORS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
The invention is directed to the use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders.
2018/0161338 RETOSIBAN FOR THE TREATMENT OF PRE-TERM LABOUR
The present invention relates to a method of treating pre-term labour with retosiban in subjects with conditions resulting in uterine overdistension including...
2018/0161337 NOVEL BICYCLIC BROMODOMAIN INHIBITORS
The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical...
2018/0161336 DNA-PK INHIBITORS
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said...
2018/0161335 METHODS TO TREAT NEUROLOGICAL DISEASES
Disclosed is a method of treating a subject who has a neurological disease. The neurological disease may be associated with altered C9ORF72 protein activity....
2018/0161334 USE OF FACTOR XA INHIBITORS FOR REGULATING GLYCEMIA
The present invention concerns a factor Xa inhibitor for use as a medicament in a method for regulating glycemia in a subject, in particular for use for...
2018/0161333 INHIBITORS OF MACROPINOCYTOSIS IN PREVENTION AND TREATMENT OF DISEASE
Described herein are pharmaceutical compositions capable of inhibiting vesicle formation and methods of treatment or prophylactic administration of these...
2018/0161332 TREATMENT OF MITOCHONDRIAL DISEASES
The present invention provides a composition comprising one or more deoxyribonucleosides for use in the treatment of a mitochondrial DNA depletion and/or...
2018/0161331 NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF
A method for inhibiting androgen activity, including administering an effective amount of a tetrahydropyridopyrimidine compound of formula (I) or a...
2018/0161330 THIENO- AND PYRROLOPYRIMIDINE ANALOGUES AS ANTICANCER AGENTS AND METHODS OF USE THEREOF
The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory...
2018/0161329 PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
The purpose of the present invention is to provide a compound having an excellent CDK4/6 inhibiting activity. The present invention is a compound represented...
2018/0161328 TREATMENT OF CANCER AND BENIGN PROLIFERATIVE DISORDERS
Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign...
2018/0161327 ANTAGONIST OF THE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) FOR USE IN THE TREATMENT OR THE PREVENTION OF...
The present invention relates to the treatment or prevention of skeletal disorders, in particular skeletal diseases, developed by patients that display...
2018/0161326 PAC-1 COMBINATION THERAPY
The invention provides compositions and methods for the induction of cancer cell death. The compositions and methods of using them include use of compositions...
2018/0161325 PHARMACEUTICAL FORMULATION CONTAINING TADALAFIL
Disclosed herein are pharmaceutical compositions comprising Tadalafil, or a salt, or derivatives thereof and pharmaceutical excipients, processes for the...
2018/0161324 SHIP1 MODULATORS AND METHODS RELATED THERETO
Compounds of formula (I): ##STR00001## where ##STR00002## n, R.sup.1, R.sup.4a, R.sup.4b, R.sup.5, R.sup.7 and R.sup.8 are defined herein, or pharmaceutically...
2018/0161323 TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM
A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic...
2018/0161322 PHARMACEUTICAL COMPOSITION
A preparation for oral administration comprising: a pregelatinized starch comprising ...
2018/0161321 Therapeutic Uses of Compounds Having Combined SERT, 5-HT3 and 5-HT1A Activity
New pharmaceutical uses of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine and pharmaceutically acceptable salts thereof are provided.
2018/0161320 INTRANASAL NALOXONE COMPOSITIONS AND METHODS OF MAKING AND USING SAME
Disclosed herein are compositions containing an opioid antagonist such as naloxone and one or more pharmaceutically acceptable excipients. The compositions may...
2018/0161319 METHODS OF ENHANCING IMMUNE RESPONSE
The present invention relates to a method of enhancing immune response in a subject.
2018/0161318 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OBESITY OR LIVER DISEASES, CONTAING TLR7 AGONIST
The present invention is based on the fact that imiquimod, which is a substance that enhances Toll-like receptor 7 (TLR7) related to the innate immunity of a...
2018/0161317 MESYLIC ACID SALT OF ACYLTHIOUREA COMPOUND, CRYSTAL OF THE SAME, AND PROCESS FOR PRODUCING THESE
An object of the present invention is to provide a salt compound of 4-(2-fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylqu- ...
2018/0161316 2-(AZAINDOL-2-YL) BENZIMIDAZOLES AS PAD4 INHIBITORS
Compounds of formula (I) wherein; R.sub.1 is hydrogen or C.sub.1-6alkyl; R.sub.2 is hydrogen, C.sub.1-6alkyl, perhalomethylC.sub.0-5alkyl-O--, or ...
2018/0161315 TREATMENT METHODS UTILIZING STEM CELL MOBILIZERS AND IMMUNOSUPPRESSIVE AGENTS
The present invention relates to the field of organ transplantation. In one aspect, the present invention provides methods of treating an organ transplant...
2018/0161314 Methods for Treating Hyperuricemia and Related Diseases
Provided herein are methods of treating gout, treating hyperuricemia, lowering serum uric acid, or the like with compounds of formula (I) have the following...
2018/0161313 Inhibitors of Mcl-1 as Drugs to Overcome Resistance to BRAF Inhibitors and MEK Inhibitors
The present invention includes compositions and methods for inhibiting MCL-1, including novel inhibitors of MCL-1, and compositions and methods for treating a...
2018/0161312 SUBSTITUTED IMIDAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are...
2018/0161311 SYNTHETIC TRITERPENOIDS AND METHODS OF USE IN THE TREATMENT OF DISEASE
The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial...
2018/0161310 COMPOUNDS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
Compounds that inhibit synaptic hyperexcitability, pharmaceutical compositions of these compounds, and methods of using the compounds and pharmaceutical...
2018/0161309 METHODS AND COMPOSITIONS INVOLVING (S)-BUCINDOLOL
Disclosed is bucindolol substantially free of its R-stereoisomer. Also disclosed are pharmaceutical compositions that include bucindolol substantially free of...
2018/0161308 SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES
Disclosed herein are self-emulsifying compositions and formulations of Diindolylmethane ("DIM") and certain derivatives of DIM, their uses and methods of...
2018/0161307 SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF
This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of...
2018/0161306 DULOXETINE SPRINKLES
The present invention relates in part a to multiparticulate sprinkle dosage form comprising duloxetine or a pharmaceutically acceptable salt thereof, having...
2018/0161305 ACETOGENIN MOLECULES HAVING ANTIPLATELET AND/OR ANTITHROMBIC ACTIVITIES, AND METHODS AND COMPOSITIONS THEREOF
The present disclosure relates, according to some embodiments, to acetogenin molecules that may have antiplatelet and/or antithronibic activities. In some...
2018/0161304 EQUINE SUPPLEMENT
Disclosed herein are methods of using nutritional supplements and specific combinations thereof to counteract exercise-induced stress and its sequelae in...
2018/0161303 Methods and Compositions for Inhibition of ATR and FANCD2 Activation
This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the...
2018/0161302 PHARMACEUTICAL COMBINATION AND USES THEREOF
The invention relates to pharmaceutical combinations comprising a vascular disrupting agent, in particular the tubulin polymerisation inhibitor BNC105, and an...
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