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Patent # Description
2018/0163277 COMPOSITIONS AND METHODS FOR DETECTION AND DISCRIMINATION OF EMERGING INFLUENZA VIRUS SUBTYPES
Compositions and methods for detecting presence of an emerging influenza virus in a sample, such as a biological sample obtained from a subject or an...
2018/0163276 METHOD AND APPARATUS FOR DETERMINING A PROBABILITY OF COLORECTAL CANCER IN A SUBJECT
A method of determining a probability that a human test subject has colorectal cancer as opposed to not having colorectal cancer is disclosed. The method...
2018/0163275 MOLECULAR ASSAY KITS
Methods, kits, and compositions for evaluating the quality of nucleic acids within a biological sample for analysis in a molecular assay are provided.
2018/0163274 CIRCULATING MICRORNA AS A MARKER FOR HEPATOCELLULAR CARCINOMA
Provided herein are methods for the diagnosis, or management of liver diseases, e.g., hepatocellular carcinoma, using profiles of the miRNAs determined from...
2018/0163273 BREAST CANCER BIOMARKERS AND METHODS OF USING SAME
The present invention provides breast cancer markers based on RECQL mutations, and related methods, uses, agents, and kits. The invention includes methods for...
2018/0163272 METHODS FOR THE DETECTION OF GENOMIC COPY CHANGES IN DNA SAMPLES
The present invention includes compositions and methods useful for the detection of a mutational change, SNP, translocation, inversion, deletion, change in...
2018/0163271 Use of PARP Inhibitors to Treat Breast or Ovarian Cancer Patients Showing a Loss of Heterozygosity
In one embodiment, the subject invention relates to a method for treatment of a breast or ovarian cancer patient that includes receiving assay results stating...
2018/0163270 INTEGRATED IMMUNO-PCR AND NUCLEIC ACID ANALYSIS IN AN AUTOMATED REACTION CARTRIDGE
In various embodiments methods detecting and/or quantifying a target analyte using immuno-PCR and optionally nucleic acid amplification are provided. In...
2018/0163269 Method for Assessing the Quality of Various Cells Including Induced Pluripotent Stem Cells
The present invention relates to a method for assessing the quality, utility and applicability of a cell according to the said method comprising the following...
2018/0163268 NANOPORE-BASED POLYMER ANALYSIS WITH MUTUALLY-QUENCHING FLUORESCENT LABELS
The invention is directed to a method for determining a monomer sequence of a polymer that is translocated through a nanopore. Monomers of the polymer are...
2018/0163267 MODULAR NUCLEOTIDE COMPOSITIONS AND USES THEREFOR
Nucleic acid compositions, methods of making and using such compositions that comprise modular functional groups that can be configured to provide desired...
2018/0163266 NUCLEOTIDE SENSING DEVICE HAVING A NANOPORE FORMED IN AN INORGANIC MATERIAL
Methods and apparatuses for sensing nucleotides are disclosed. A related nucleotide sensing device may include an insulator having an electrode well and a...
2018/0163265 UNBIASED IDENTIFICATION OF DOUBLE-STRAND BREAKS AND GENOMIC REARRANGEMENT BY GENOME-WIDE INSERT CAPTURE SEQUENCING
The invention provides for systems, methods, compositions, and kits for the complete characterization of targeted nuclease specificity which necessitates...
2018/0163264 Detection of Nucleic Acid Molecules
The present invention relates to methods for the detection of nucleic acid molecules at the lower detection limit.
2018/0163263 HIGH-SENSITIVITY METHOD FOR DETECTING TARGET NUCLEIC ACID
Provided are: a method with which it is possible to suppress nucleic-acid amplification of non-target nucleic acids and to selectively nucleic-acid amplify a...
2018/0163262 PREDICTING PROGRESSION TO ADVANCED AGE-RELATED MACULAR DEGENERATION USING A POLYGENIC SCORE
The present invention relates to methods for identifying individuals with intermediate age-related macular degeneration (AMD) who possess a greater risk of...
2018/0163261 METHODS AND APPARATUSES FOR IMPROVING MUTATION ASSESSMENT ACCURACY
Embodiments are provided that relate to methods, systems, kits, computer-readable medium, and apparatuses comprising a computer-based variant calling model...
2018/0163260 GENE POLYMORPHISM ANALYSIS DEVICE
A gene polymorphism analysis device for determining the allele mating type of a gene polymorphism on the basis of the first fluorescence intensity change over...
2018/0163259 MULTIPLEX INVASIVE CLEAVAGE ASSAYS
The present disclosure relates to compositions and methods, and related systems, products and kits, for performing temperature-dependent multiplex invasive...
2018/0163258 REACTION MIXTURE CONTAINING PROBES HAVING INDISTINGUISHABLE LABELS
Reaction mixture containing an analyte probe and an internal control probe, where the analyte probe and the internal control probe target different nucleic...
2018/0163257 BIOPROBES AND METHODS OF USE THEREOF
Disclosed are biomolecule based bioprobes that exhibit improved water solubility and mono layer-forming properties with substantially little or no aggregation...
2018/0163256 PRESERVATION OF CELL-FREE NUCLEIC ACIDS
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic...
2018/0163255 Nucleic Acid Preparation Method
A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least...
2018/0163254 METHODS FOR ASSEMBLING DNA MOLECULES
The invention provides compositions and methods for assembling a DNA molecule having a desired sequence. The methods involve contacting a DNA polymerase,...
2018/0163253 METHODS FOR PRODUCING A PAIRED TAG FROM A NUCLEIC ACID SEQUENCE AND METHODS OF USE THEREOF
Methods for producing a paired tag from a nucleic acid sequence are provided in which the paired tag comprises the 5' end tag and 3' end tag of the nucleic...
2018/0163252 SQUARE WAVE THERMAL CYCLING
Embodiments disclosed herein relate to methods and systems for analysis of melting temperatures, and particularly to analysis of duplex nucleic acids.
2018/0163251 TARGET REGION ENRICHMENT METHOD BASED ON MULTIPLEX PCR, AND REAGENT
Provided are a target region enrichment method based on multiplex PCR, and a reagent, the method comprising: connecting a first linker and a second linker...
2018/0163250 Screening Broths Comprising Esculatin Compounds for the Detection of Specific Microorganisms
The present invention relates to the use of an esculatin compound in a method for detecting the presence or absence of an enzymatic reaction in a sample...
2018/0163249 Methods and Systems for Determining ADAMTS13 Enzyme Activity
Disclosed are methods and systems for the analysis activity of enzyme disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13...
2018/0163248 METHOD AND AGENTS FOR DETECTING LUCIFERASE ACTIVITY
The invention provides methods and reagents for detecting luciferase in biological samples. The methods and reagents of the present invention allow detecting...
2018/0163247 SELECTIVE ENRICHMENT MEDIUM FOR CARBAPENEM-RESISTANT BACTERIA
The present invention relates to a method for direct detection and differentiation of carbapenem-resistant bacteria in a sample comprising (i) inoculation with...
2018/0163246 METHOD, APPARATUS AND ELECTROCHEMICAL TEST DEVICE
A method of processing data from a test device is provided. The method comprises determining a concentration of a first analyte in a fluid sample using first...
2018/0163245 METHODS AND DEVICES TO DETECT STROKE IN A SUBJECT
The invention describes a method of determining the presence of acute cerebral ischaemic disorder in a subject comprising: a. measuring the concentration of...
2018/0163244 HEAT TREATMENT TO PRODUCE GLYCOSIDES
Disclosed are methods of releasing or enriching for steviol glycosides produced by yeast. The disclosed methods enhance or improve the release or enrichment of...
2018/0163243 Enzymatic Systems and Methods for Synthesizing Nicotinamide Mononucleotide and Nicotinic Acid Mononucleotide
Enzyme-based systems and methods for synthesizing the NAD precursors NMN and NaMN are disclosed. Such methods and systems utilize a mutated form of...
2018/0163242 GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF FOR BIOMASS HYDROLYSIS
The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase...
2018/0163241 METHODS OF PRODUCING EPIMERASES AND BENZYLISOQUINOLINE ALKALOIDS
A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the...
2018/0163240 COMPOSITIONS AND METHODS FOR BIOLOGICAL PRODUCTION OF METHIONINE
The present disclosure provides compositions and methods for using modified hydrogenotrophic microorganisms capable of biologically utilizing or converting CO...
2018/0163239 EXPRESSION OF RECOMBINANT TETRACYCLINE EFFLUX PUMPS FOR THE PRODUCTION OF LYSINE OR LYSINE-DERIVED PRODUCTS,...
The present invention provides a mutant polypeptide comprising the amino acid sequence of Escherichia coli tetracycline efflux pump A (TetA), and a...
2018/0163238 PREPARATION CONTAINING ERGOTHIONEINE, PREPARATION METHOD THEREOF AND USE OF MUSHROOM EXTRACELLULAR FERMENT LIQUOR
Disclosed is a preparation containing ergothioneine, the ergothioneine is provided by an extracellular ferment liquor which is obtained by removing the mycelia...
2018/0163237 Modified Cyanobacteria
Provided is a cyanobacterium improved in fatty acid productivity. A method for producing a modified cyanobacterium, comprising causing loss of function of a...
2018/0163236 mtgA GENE-DEFICIENT MICROORGANISM
Provided is a bacterial strain having a mutation in the gene that codes for monofunctional peptidoglycan transglycosylase (MtgA), wherein the mutation...
2018/0163235 BIOSYNTHESIS OF PHENYLPROPANOIDS AND PHENYLPROPANOID DERIVATIVES
Provided herein are recombinant hosts and methods for producing phenylpropanoid and phenylpropanoid derivative compounds. It was found that tyrosine ammonia...
2018/0163234 COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS
This invention generally relates to natural gas and methylotrophic energy generation, bio-generated fuels and microbiology. In alternative embodiments, the...
2018/0163233 METHODS AND PRODUCTS FOR PRODUCING ENGINEERED MAMMALIAN CELL LINES WITH AMPLIFIED TRANSGENES
Methods of inserting genes into defined locations in the chromosomal DNA of cultured mammalian cell lines which are subject to gene amplification are...
2018/0163232 A METHOD FOR MAKING SITE-DIRECTED MODIFICATION TO PLANT GENOMES BY USING NON-INHERITABLE MATERIALS
The invention disclosed a method for conducting site-directed modification to a plant genome using non-inheritable materials. The method provided in the...
2018/0163231 MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME
The present invention is directed to non-naturally occurring peptides containing a membrane-penetrating amino acid sequence and further at least one...
2018/0163230 RECOMBINANT HVT VECTORS EXPRESSING MULTIPLE ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising...
2018/0163229 NOVEL RECOMBINANT ADENO-ASSOCIATED VIRUS CAPSIDS CONTAINING A DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) OR...
The present invention relates to variant AAV capsid polypeptides containing designed ankyrin repeat proteins (DARPins), wherein the variant capsid polypeptides...
2018/0163228 METHOD FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS
A method for producing recombinant adeno-associated virus, the method including: (1) transforming a gene of interest (GOI) into a recombinant baculovirus,...
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