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Patent # Description
2018/0171415 SYSTEMS AND METHODS TO DETECT RARE MUTATIONS AND COPY NUMBER VARIATION
The present disclosure provides a system and method for the detection of rare mutations and copy number variations in cell free polynucleotides. Generally, the...
2018/0171414 GEP5 MODEL FOR MULTIPLE MYELOMA
The invention provides, inter alia, methods of prognosing a subject with, or suspected of having, multiple myeloma. In certain embodiments, the methods entail...
2018/0171413 HEAD AND NECK SQUAMOUS CELL CARCINOMA ASSAYS
We queried DNA from saliva or plasma of 93 HNSCC patients, searching for somatic mutations or human papillomavirus genes, collectively referred to as tumor...
2018/0171412 TARGETED THERAPIES FOR CANCER
Various embodiments provide compositions and methods for detecting cancers containing an NRG1 fusion event and treating a patient with a therapeutic agent that...
2018/0171411 GFRalpha1 AS A BIOMARKER FOR CISPLATIN-INDUCED CHEMORESISTANCE AND METASTASIS
Certain embodiments are directed to methods and composition for detecting the level of GFR.alpha.1 in cancers and treating same.
2018/0171410 METHOD FOR IDENTIFYING SUBJECTS WITH AGGRESSIVE MELANOMA SKIN CANCER ATDIAGNOSIS
This disclosure is in the field of molecular biology and medical diagnosis and provides means and methods for determining the prognosis and disease outcome of...
2018/0171409 SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING CHROMOSOME COPY NUMBER
Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of...
2018/0171408 Characterizing Gastro-Intestinal Disease
A method for characterizing a gastro-intestinal disease in a subject involves comparing ratios of expression levels of genes in a biological sample from a...
2018/0171407 GENETIC POLYMORPHISMS ASSOCIATED WITH AUTOINFLAMMATORY DISEASES, METHODS OF DETECTION AND USES THEREOF
The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoinflammatory diseases such as psoriasis....
2018/0171406 IDENTIFICATION OF EPIGENETIC BIOMARKERS IN THE SALIVA OF CHILDREN WITH AUTISM SPECTRUM DISORDER
The present invention relates to systems, devices, collections, techniques, and methods for diagnosing autism spectrum disorder (ASD) in a subject in addition...
2018/0171405 THERAPEUTIC AND DIAGNOSTIC METHODS FOR IL-33-MEDIATED DISORDERS
The invention relates to methods of treating a patient suffering from an IL-33-mediated disorder, such as asthma, comprising administering to the patient an...
2018/0171404 METHOD AND SYSTEM FOR ESTIMATING WHETHER A FEMALE IS PREGNANT BASED ON A BLOOD SAMPLE
A method for estimating whether a female is pregnant, said method comprising measuring allele presences (D) for a plurality of genetic markers of at least one...
2018/0171403 METHOD FOR DETERMINING THE RISK OF PRETERM LABOR
Provided is a method for determining the risk of preterm labor in a pregnant female subject. The method comprises detecting the expression level of one or more...
2018/0171402 NUCLEIC ACID SEQUENCING WITH NANOSCALE ELECTRODE PAIRS
Sequencing methods, devices, and systems are described. Arrays of nanoscale electronic elements comprising two electrodes separated by an insulating layer are...
2018/0171401 METHODS FOR OBTAINING A SEQUENCE
The invention generally relates to methods for obtaining a sequence, such as a consensus sequence or a haplotype sequence. In certain embodiments, methods of...
2018/0171400 Small RNA Capture, Detection and Quantification
Methods, compositions and kits for capturing, detecting and quantifying mature small RNAs are provided herein. Embodiments of the methods comprise ligating 5'...
2018/0171399 Helicase Suppression of Non-Template Amplification
Provided herein is a method for reducing amplification of non-template molecules in a nucleic acid sample. In certain embodiments, the method involves adding a...
2018/0171398 IMPROVEMENTS IN AND RELATING TO NUCLEIC ACID PROBES AND HYBRIDISATION METHODS
The invention provides a method of nucleic acid sequence hybridisation comprising the steps of: a) hybridising one or more samples comprising nucleic acids...
2018/0171397 Compositions and Methods for Analyzing Modified Nucleotides
Methods and compositions are provided for identifying any of the presence, location and phasing of methylated and/or hydroxymethylated cytosines in nucleic...
2018/0171396 IMAGING INDIVIDUAL MRNA MOLECULES USING MULTIPLE SINGLY LABELED PROBES
A method for probing a target sequence of messenger ribonucleic acid molecules (mRNA's) in a fixed, permeabilized cell, said target sequence including at least...
2018/0171395 Enzymatic methods for genotyping on arrays
The invention relates to methods for enzymatic, genotyping of polymorphisms on solid supports. In some aspects the methods include ligation of allele or base...
2018/0171394 Methods and Compositions for Cannabis Characterization
Provided are methods for determining if a cannabis sample comprises hemp or marijuana, or Cannabis sativa and/or Cannabis indica as well as primers and kits...
2018/0171393 MONITORING AND ANALYSIS OF NUCLEIC ACID HYBRIDIZATION STATE AND AMPLIFICATION USING L-DNA
Systems, methods, and compositions for monitoring and analyzing nucleic acid hybridization state using L-DNA probes are described. The methods include adding...
2018/0171392 FLUID IDENTIFICATION SYSTEM AND PRODUCTION AND USE THEREOF
A fluid identification system comprising a plurality of particles, each particle encapsulating therein at least one tracer material having an identifiable DNA,...
2018/0171391 Methods and Compositions For Sorting and/or Determining Organisms
This invention is directed to methods and compositions for sorting and/or determining microscopic organisms or cells. The methods and compositions are directed...
2018/0171390 METHOD AND SYSTEM FOR ESTIMATING A GENDER OF A FOETUS OF A PREGNANT FEMALE
A method for estimating a gender of a foetus of a pregnant female, said method comprising measuring allele presences (Dx) for a first plurality of genetic...
2018/0171389 METHOD OF TREATING CROHN'S DISEASE
The invention relates to the treatment of inflammatory bowel disease characterised by chronic inflammation. In particular, the invention relates to methods of...
2018/0171388 NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF TICK-BORNE PATHOGENS
The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B....
2018/0171387 SYSTEMS AND METHODS FOR FLUORESCENCE DETECTION WITH A MOVABLE DETECTION MODULE
A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one...
2018/0171386 Long Adapter Single Stranded Oligonucleotide (LASSO) Probes to Capture and Clone Complex Libraries
Long adapter single strand oligonucleotide (LASSO) probes that can be used to capture and clone thousands of kilobase-sized DNA fragments in a single reaction,...
2018/0171385 ALKB -FACILITATED RNA METHYLATION SEQUENCING (ARM-SEQ)
In various embodiments, the invention teaches methods for detecting ribonucleic acid (RNA) molecules that contain certain chemical modifications using...
2018/0171384 COPY NUMBER PRESERVING RNA ANALYSIS METHOD
The present invention provides a method for generating an amplified nucleic acid portion of a template RNA molecule, comprising after having obtained a...
2018/0171383 METHODS FOR NUCLEIC ACID IDENTIFICATION
Provided herein are methods and devices for obtaining nucleotide sequence information from nucleic acid and nucleic acid samples. The methods involve modifying...
2018/0171382 BRANCHED PROXIMITY HYBRIDIZATION ASSAY
The invention relates to a method for detecting the proximity of at least two biomolecules using branched DNA technology. The assay is called branched...
2018/0171381 COMPOSITIONS, METHODS, AND PLANT GENES FOR THE IMPROVED PRODUCTION OF FERMENTABLE SUGARS FOR BIOFUEL PRODUCTION
Described herein are compositions comprising at least one auxin transport inhibitor for pre-treating a plant or seed to increase saccharification, or...
2018/0171380 ENGINEERED ENZYMES WITH METHIONINE-GAMMA-LYASE ENZYMES AND PHARMACOLOGICAL PREPARATIONS THEREOF
Methods and composition related to the engineering of a novel protein with methionine-.gamma.-lyase enzyme activity are described. For example, in certain...
2018/0171379 IMMOBILIZED ENZYMATIC REACTOR
An immobilized enzymatic reactor can include a wall defining a chamber having an inlet and an outlet; a solid stationary phase covalently linked to an enzyme...
2018/0171378 SENSORS AND METHODS FOR CAPTURE, KILLING, AND RELEASE OF BACTERIA
There is provided a renewable sensor for sensing or selectively capturing a targeted bacteria in a fluid. The renewable sensor includes a surface, the surface...
2018/0171377 DROPLET ARRAY FOR SINGLE-CELL ANALYSIS
Techniques, systems, and devices are described for implementing a droplet array for single-cell analysis. A method of conducting single-cell analysis comprises...
2018/0171376 METHOD FOR EVALUATION OF GRAFTS
A method and system for evaluating the competence for transplantation of a graft sample containing cells capable of multinucleation are provided. In one form,...
2018/0171375 METHODS AND COMPOSITIONS FOR DIAGNOSING BACTERIAL VAGINOSIS
Disclosed are methods for diagnosing Bacterial Vaginosis (BV). The disclosed methods generally include detecting select species of Eggerthella and/or...
2018/0171374 Microorganism For Expressing A Human Membrane Protein
The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type,...
2018/0171373 ASSAYS AND OTHER REACTIONS INVOLVING DROPLETS
The present invention generally relates to droplets and/or emulsions, such as multiple emulsions. In some cases, the droplets and/or emulsions may be used in...
2018/0171372 METHODS FOR THE SYNTHESIS OF CHIRAL KYNURENINE COMPOUNDS
Provided are methods for synthesizing compounds, including chiral kynurenine compounds. The methods are suitable for large-scale manufacture and produce the...
2018/0171371 METHODS FOR CONTINUOUS PRODUCTION OF PRODUCTS FROM MICROORGANISMS
The present invention relates to improved methods for producing biosynthetic products in a cascade of bioreactors. In particular the present invention relates...
2018/0171370 A MICROORGANISM HAVING ENHANCED PRODUCTIVITY OF LACTIC ACID AND A PROCESS FOR PRODUCING LACTIC ACID USING THE SAME
The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased...
2018/0171369 DIBASIC ORGANIC ACID PRODUCING STRAIN AND PREPARATION AND APPLICATION OF SAME
Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or...
2018/0171368 PROCESS FOR THE BIOLOGICAL PRODUCTION OF METHACRYLIC ACID AND DERIVATIVES THEREOF
A process of producing methacrylic acid and/or derivatives thereof including the following steps: (a) biologically converting isobutyryl-CoA into...
2018/0171367 Method for High-efficiency Production of Pinoresinol Using an H2O2 Auto-scavenging Cascade
The present invention provides a method for high-efficiency production of pinoresinol by use of an H.sub.2O.sub.2 auto-scavenging enzymatic cascade. It uses...
2018/0171366 XYLITOL PRODUCING METSCHNIKOWIA SPECIES
Provided herein are Metschnikowia species that produce xylitol from xylose when cultured, as well as methods to make and use these Metschnikowia species.
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