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Patent # Description
2018/0171315 POLYPEPTIDES HAVING XANTHAN DEGRADING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to polypeptides having xanthan degrading activity, and polynucleotides encoding the polypeptides. The invention also relates to...
2018/0171314 THERMOSTABLE CAS9 NUCLEASES
Thermostable Cas9 nucleases. The present invention relates to the field of genetic engineering and more particularly to nucleic acid editing and genome...
2018/0171313 POLYPEPTIDES WITH LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to isolated polypeptides with lipase activity. The invention also relates to polynucleotides encoding the polypeptides; nucleic...
2018/0171312 VARIANT THIOESTERASES AND METHODS OF USE
The present invention relates to variant thioesterases and their use in plants, e.g., to increase enzymatic activity and to promote increased production of...
2018/0171311 MODIFIED TRANSPOSASES FOR IMPROVED INSERTION SEQUENCE BIAS AND INCREASED DNA INPUT TOLERANCE
Presented herein are transposase enzymes and reaction conditions for improved fragmentation and tagging of nucleic acid samples, in particular altered...
2018/0171310 PRODUCTION OF POLYUNSATURATED FATTY ACIDS (PUFAs) USING A NOVEL MODULAR DOCOSAHEXAENOIC ACID (DHA) SYNTHASE
This disclosure concerns a novel modular docosahexaenoic acid (DHA) synthase and recombinant host organisms genetically modified with such synthase and one or...
2018/0171309 IMMORTALISED CHICKEN EMBRYO FIBROBLASTS
The present invention relates to immortalised chicken embryo fibroblasts, to cell cultures comprising such immortalised cells, to vaccines comprising such...
2018/0171308 DEVELOPMENT OF DENGUE VIRUS VACCINE COMPONENTS
The invention is related to a dengue virus or chimeric dengue virus that contains a mutation in the 3' untranslated region (3'-UTR) comprising a .DELTA.30...
2018/0171307 PESTIVIRUS VACCINES FOR CONGENITAL TREMORS
The present invention relates to a vaccine for protecting a piglet against diseases associated with a novel pestivirus. The vaccine commonly includes a...
2018/0171306 METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES
Methods of using viruses labeled with alkyne-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal...
2018/0171305 USE OF PHOSPHOLIPID SCRAMBLASE INHIBITORS FOR MODULATING INFLAMMATORY IMMUNE RESPONSES
The finding that phosphatidylserine (PtdSer) exposure on the outer leaflet of virally transduced cells triggers their engulfment by resident immune cells is...
2018/0171304 CONTINUOUSLY BIOPRINTED MULTILAYER TISSUE STRUCTURE
Provided herein are synthetic living tissue structures comprising multiple layers of fibers deposited in solidified form from a 3D bioprinter, together with...
2018/0171303 COMBINED CHEMICAL AND GENETIC APPROACHES FOR GENERATION OF INDUCED PLURIPOTENT STEM CELLS
The present invention provides for identification and use of small molecules to induce pluripotency in mammalian cells as well as other methods of inducing...
2018/0171302 Genetically Modified IPS Cells That Carry a Marker to Report Expression of Neurogenin3, TPH2, FOXO1 and/or...
Provided herein are insulin-negative cells that have been genetically modified to report expression of one or more target genes. Exemplified are reporter cell...
2018/0171301 DRYING FORMULATON FOR HYDROGEL MICROCARRIERS
A method of making a cell culture article is provided. The method includes forming a microcarrier from a microcarrier composition comprising a polygalacturonic...
2018/0171300 PASSAGING AND HARVESTING FORMULATION AND METHOD FOR HUMAN PLURIPOTENT STEM CELLS
Formulations and methods are disclosed for the harvesting and subsequent passaging of human pluripotent stem cells without the use of enzymes and/or scraping...
2018/0171299 FUNCTIONAL CELL SHEET USING ELECTRICALLY ACTIVATED CONDUCTIVE POLYMER, AND METHOD OF PRODUCING SAME
The present invention relates to a functional cell sheet using an electroactive conductive polymer and a method of preparing the same, and more particularly,...
2018/0171298 METHODS FOR IMPROVING FUNCTIONALITY IN NK CELL BY GENE INACTIVATION USING SPECIFIC ENDONUCLEASE
The present invention relates to methods for improving therapeutic activity of NK cell, such as their cytotoxic/cytolytic activity, to be used in...
2018/0171297 TARGETING BCL11A ENHANCER FUNCTIONAL REGIONS FOR FETAL HEMOGLOBIN REINDUCTION
Provided herein are nucleic acid molecules that target the BCL11A enhancer functional regions, compositions comprising the nucleic acid molecules and methods...
2018/0171296 Dendritic Cell Generator
Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from...
2018/0171295 BUOYANCY ENABLED SEPARATION METHOD AND SYSTEM
A buoyancy enabled separation method for isolation from a sample including a variety of different cells a sparse subset of cells that is differentiated by a...
2018/0171294 IN VITRO ARTIFICIAL LYMPH NODE METHOD FOR SENSITIZATION AND EXPANSION OF T CELLS FOR THERAPY AND EPITOPE MAPPING
A method of creating a microenvironment for culture expansion of T cells. The expanded T cells can be used for a variety of therapeutic and research purposes.
2018/0171293 CYTOPHERESIS CARTRIDGES AND USE THEREOF
The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions within a subject and to related...
2018/0171292 METHOD OF PRODUCING RETINAL PIGMENT EPITHELIAL CELL SHEET
The present invention provides a method of producing a cell sheet including the following steps (1) seeding and culturing retinal pigment epithelial cells on a...
2018/0171291 DERIVATION OF ENDOTHELIAL CELLS FROM MAMMALIAN PLUIRPOTENT STEM CELLS
This invention relates, e.g., to a method for differentiating mammalian (e.g., human) pluripotent stem cells (PSCs) into endothelial cells (ECs) in vitro, by...
2018/0171290 METHOD OF PRODUCING PROGENITOR CELLS FROM DIFFERENTIATED CELLS
The present invention provides a method of producing progenitor cells, such as cells capable of being differentiated into a plurality of different cell types,...
2018/0171289 SYSTEMS, METHODS AND APPARATUSES FOR PROCESSING PLANT EMBRYOS
A pick-and-place system for plant embryos includes a tray for receiving a suspension of plant embryos. The tray is movable to repeatedly reposition the plant...
2018/0171288 METHODS OF TREATING CANCER
Compositions and methods of treating a subject with cancer are described. The methods include administering to the subject a therapeutically effective amount...
2018/0171287 Methods of Measuring Cell Purity for Making Quality Control Determinations and Related Compositions
This disclosure relates to methods of detecting and quantifying low concentrations of cells in a sample with targeted nanoparticles having Raman reporters...
2018/0171286 Peptide Conjugated Hydrogel Substrate for the Maintenance and Expansion of Human Pluripotent Stem Cells
Compositions useful for propagation of pluripotent stem cells are provided. The compositions comprise a polysaccharide hydrogel linked to a peptide fragment of...
2018/0171285 PROPAGATING MICROORGANISMS & RELATED METHODS & SYSTEMS
Disclosed are methods and systems for propagating microorganisms such as yeast using a carbon source that includes glycerol and a nutrient source that includes...
2018/0171284 DEVICES, SYSTEMS AND METHODS FOR THE PRODUCTION OF HUMANIZED GUT COMMENSAL MICROBIOTA
One embodiment provides a commensal gut production platform for ex vivo production of human gut commensal microbiota. Another embodiment provides devices,...
2018/0171283 STREPTOMYCES AND METHOD FOR PRODUCING MILBEMYCIN A3 USING SAME
Provided are a Streptomyces (Streptomyces hygroscopicus) HS7523 and a method for preparing milbemycin A3 by culturing the Streptomyces. The Streptomyces...
2018/0171282 CORDYCEPS CICADAE MYCELIUM ACTIVE SUBSTANCES, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND APPLICATION...
A method of preparing Cordyceps cicadae mycelium active substances for preventing and/or treating xerophthalmia is provided. The method comprises: (a)...
2018/0171281 CORIOLIS FLOW METER FOR MEASURING PROPERTIES OF A FLUID AND METHOD THEREFOR
A Coriolis flow meter for measuring one or more properties of a fluid is described herein which involves a modular configuration, and includes a fluid flow...
2018/0171280 CELL CULTURE EXPOSURE SYSTEM (CCES)
An vitro air-liquid interface (ALI) exposure of cultured cells makes it possible to examine the toxicological properties of the tested air. A method for...
2018/0171279 CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE
Methods of protein production in continuous perfusion mammalian cell culture bioreactors are provided. Methods for continuous perfusion culture by allowing...
2018/0171278 Liquid Flow-Circulation Chamber, Cell Concentration Device, and Cell Concentration System
The present invention is directed to provide cell concentration devices and cell concentration systems having a novel liquid flow-circulation chamber. It is a...
2018/0171277 MULTI-CHAMBERED CELL CULTURE DEVICE TO MODEL ORGAN MICROPHYSIOLOGY
A method of testing an analyte can include using a cell culture device that includes: at least three distinct chambers between the top wall and bottom wall....
2018/0171276 DEVICE AND METHOD FOR ANALYSIS OF TISSUE CONSTRUCTS
The present invention provides an integrated microphysiological device and fabrication methods thereof, as well as methods of use to perform biological assays.
2018/0171275 PHOTOBIOREACTOR SYSTEMS AND METHODS
An algal growth system including a first flexible sheet material mounted in a first mounted geometry such that the height is greater than the width of the...
2018/0171274 ADDITION OF INGREDIENTS HAVING AROMATIC COMPONENTS TO A BEVERAGE
A method for dry hopping a beverage such as young beer includes the steps of removing a portion of the beverage from the fermentation tank, mixing it with hops...
2018/0171273 Fermentation Monitoring and Management
A fermentation monitoring system may measure the weight of a fermenting product to determine the progress of fermentation. The weight of a fermenting batch may...
2018/0171272 MANGANESE BLEACH CATALYST GRANULES FOR USE IN DISHWASH DETERGENTS
The present invention relates to co-granules comprising an enzyme and a bleach catalyst and to their use in bleach-containing granular automatic dishwash (ADW)...
2018/0171271 LAUNDRY DETERGENT COMPOSITION, METHOD FOR WASHING AND USE OF COMPOSITION
The patent application discloses the use of enzymes capable of degrading cellulosic material for removing and preventing build up of fuzz and pills and for...
2018/0171270 LAUNDRY METHOD, USE OF POLYPEPTIDE AND DETERGENT COMPOSITION
The present invention concerns a method for laundering a textile, the use of a polypeptide having DNase activity and a detergent composition comprising a...
2018/0171269 LAUNDRY METHOD
The present invention concerns the use of a cutinase for preventing built up and/or removal of fuzz and pills, a method for laundering a textile and a...
2018/0171268 FABRIC AND HOME CARE PRODUCTS
This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such...
2018/0171267 Laundry Method, Use of Polypeptide and Detergent Composition
The present invention concerns a method for laundering a textile, the use of an enzyme having DNase activity and a detergent composition comprising an enzyme...
2018/0171266 AQUEOUS COMPOSITION SUITABLE FOR CLEANING AND PROTECTION COMPRISING SILICA NANOPARTICLES, COPOLYMER OF...
Compositions include a water-soluble polymer, silica nanoparticles, and a combination of a nonionic and anionic dispersed in an aqueous liquid phase. The...
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