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Patent # Description
2018/0179516 METHODS TO ACCELERATE ANTIBODY DIVERSIFICATION
Methods for increasing somatic hypermutation of antibodies, especially in vitro expression of an isolated retroviral protein in an isolated mammalian...
2018/0179515 MAGNETIC NANOSTRUCTURE FOR DETECTING AND ISOLATING CELL-FREE DNA COMPRISING CATIONIC POLYMER AND...
Provided is a magnetic nanostructure for detecting and isolating cell-free DNA (cfDNA) that including a cationic polymer and a magnetic-nanoparticle-containing...
2018/0179514 METHOD FOR ISOLATING POLY(A) NUCLEIC ACIDS
The present invention pertains inter alia to a method for isolating poly(A) nucleic acids having a single stranded poly(A) stretch from a nucleic acid...
2018/0179513 METHOD OF BREEDING EUKARYOTE USING PROTEIN HAVING DOUBLE-STRANDED DNA CLEAVAGE ACTIVITY
A method includes introducing a protein having double-stranded DNA cleavage activity itself into the eukaryote or a part of the eukaryote, and rearranging DNA...
2018/0179512 Novel self-photosensitized nonphotosynthetic microorganism
The present invention provides for a genetically modified microorganism capable of photosynthesizing an organic compound from carbon dioxide, wherein the...
2018/0179511 PROTEIN HAVING SYNTHETIC ACTIVITY FOR IMIDAZOLE DIPEPTID AND PRODUCTION METHOD OF IMIDAZOLE DIPEPTIDE
The present invention provides L-amino acid .alpha.-ligase represented by sequence number 1 (SEQ ID NO. 1), which is a mutant protein including substitution of...
2018/0179510 VARIANT OF D-PSICOSE 3-EPIMERASE AND USES THEREOF
The present invention relates to an improved variant of a D-psicose 3-epimerase and its uses.
2018/0179509 DEGRON FUSION CONSTRUCTS AND METHODS FOR CONTROLLING PROTEIN PRODUCTION
Engineered fusion proteins comprising a self-excising degron for controlling protein production are disclosed. In particular, the inventors have constructed...
2018/0179508 POLYPEPTIDES HAVING MANNANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to polypeptides, isolated from Myrothecium roridum, having mannanase activity, catalytic domains, and carbohydrate binding...
2018/0179507 NOVEL XYLANASE
Provided is a novel xylanase having high xylanase activity. A protein consisting of an amino acid sequence described in the following (a), (b) or (c) and...
2018/0179506 Polypeptides Having Endoglucanase Activity and Polynucleotides Encoding Same
The present invention relates to polypeptides having endoglucanase activity, catalytic domains, and polynucleotides encoding the polypeptides or catalytic...
2018/0179505 Polypeptides Having Endoglucanase Activity And Polynucleotides Encoding Same
The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding...
2018/0179504 POLYPEPTIDES HAVING TREHALASE ACTIVITY AND THE USE THEREOF IN PROCESS OF PRODUCING FERMENTATION PRODUCTS
The present invention relates to polypeptides having trehalase activity. The invention also relates to nucleic acid constructs, vectors, and host cells...
2018/0179503 EDITING OF CCR5 RECEPTOR GENE TO PROTECT AGAINST HIV INFECTION
Provided herein are systems, compositions, and methods of introducing protective and/or loss-of-function variants of CCR5 and CCR2. Variants may be introduced...
2018/0179502 Nucleic Acid Analogue-Guided Chemical Nuclease System, Methods and Compositions
Nucleic acid analogue-guided chemical nuclease systems, methods and compositions, which can manipulate the genome DNA sequence in a sequence-specific manner....
2018/0179501 COMPOSITIONS AND METHODS FOR TRANSIENT DELIVERY OF NUCLEASES
The disclosure in some aspects relates to recombinant adeno-associated viruses having nuclease grafted to one or more capsid proteins. In some aspects, the...
2018/0179500 MODIFIED ENZYMES
The invention relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing...
2018/0179499 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES
The description provides, inter alia, recombinant microorganisms, engineered metabolic pathways, chemical catalysts, and products produced through the use of...
2018/0179498 Molecular Cloning and Expression of cDNA Encoding O-methyltransferase Isolated from Mangifera Indica
The present invention relates to the cloning and expression of cDNA encoding O-methyl transferase for catalyzing the synthesis of vital volatile flavor...
2018/0179497 Artificial immune cell emulating selected properties of granulocytes utilizing Fenton-type reactions
An artificial immune cell emulating certain properties of the granulocytes is disclosed as a construct or aggregate of several constituent particles that...
2018/0179496 GENERATING MATURE LINEAGES FROM INDUCED PLURIPOTENT STEM CELLS WITH MECP2 DISRUPTION
Provided herein are methods for the efficient in vitro maintenance, expansion, culture, and/or differentiation of pluripotent cells with disruption of the...
2018/0179495 Growth and Survival Compositions for Cells Capable of Producing Antibodies and Methods Related Thereto
This disclosure relates to growth media and environments for in vitro culturing of cells that produce or are capable of producing antibodies. In certain...
2018/0179494 CULTURE MEDIUM FOR GENERATING MICROGLIA FROM PLURIPOTENT STEM CELLS AND RELATED METHODS
Described herein are cell culture media useful for the differentiation of human pluripotent stem cells into microglia. The methods described herein relate to...
2018/0179493 MULTILAYER SHEET OF CELLS
A multilayer sheet of cells, comprising a layer of endothelial cells, and a layer of podocytes is disclosed.
2018/0179492 ISOLATION OF NON-EMBRYONIC STEM CELLS AND USES THEREOF
The invention described herein relates to methods of isolating non-embryonic stem cell, e.g., adult stem cell, from a non-embryonic tissue, e.g., an adult...
2018/0179491 METHOD FOR CONTROLLING DIFFERENTIATION OF EMBRYONIC STEM CELLS INTO ADIPOCYTES OR KIDNEY PRECURSOR CELLS BY...
The present disclosure relates to a method for controlling the differentiation of embryonic stem cells into adipocytes or kidney precursor cells by regulating...
2018/0179490 CELL COMPOSITION DEPLETED FROM TCRab and CD45RA POSITIVE CELLS
The invention is directed to a method for the preparation of a cell population from a sample originating from bone marrow or blood, comprising the steps a)...
2018/0179489 DIGESTIBLE SUBSTRATES FOR CELL CULTURE
A cell culture article is provided. The cell culture substrate includes a polygalacturonic acid compound selected from at least one of: pectic acid or salts...
2018/0179488 METHOD FOR RESTORING SENSITIVITY OF ANTIBIOTIC RESISTANT BACTERIA TO ANTIBIOTICS AND REDUCING THE EXPRESSION OF...
A method for restoring the sensitivity of antibiotic resistant bacteria to antibiotics and a method for reducing the expression of hilA gene in animals. In...
2018/0179487 OBSERVATION APPARATUS
Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can...
2018/0179486 SENSOR INTERFACE FOR SINGLE-USE CONTAINERS
A single-use sensor interface for coupling a single-use container to a re-usable sensing instrument is provided. The single-use sensor interface includes a...
2018/0179485 SYSTEM AND METHOD OF USING A MICROFLUIDIC ELECTROPORATION DEVICE FOR CELL TREATMENT
A system and method of using a microfluidic electroporation device for cell treatment is provided. The cell or exosome treatment system can include a...
2018/0179483 IMAGING APPARATUS FOR EXPERIMENTAL USE, EXPERIMENTAL SYSTEM, AND CONTROL METHOD OF EXPERIMENTAL SYSTEM
An experimental system includes an imaging unit which generates image data by imaging a sample, and an observation moving mechanism which changes a position of...
2018/0179482 Flexible Fermentation Vessel and Uses Thereof
The present invention relates to a flexible fermentation, storage, transportation, and dispensing vessel and, more particularly, to a vessel that is structured...
2018/0179481 METHOD FOR PRODUCING CHIP FOR CELL CULTURE
A method for producing a chip for cell culture that enables production of a microchannel structure, enables mass production at low cost, and also has functions...
2018/0179480 PLANT FOR DEALCOHOLISING ALCOHOLIC BEVERAGES
A plant for dealcoholising alcoholic beverages includes a rectification column having at least one inlet for the alcoholic beverage, a sump and a top. The...
2018/0179479 COMPRESSED YEAST FOR DIRECT INOCULATION OF A FRUIT OR VEGETABLE SUBSTRATE
The present invention relates to a novel form of compressed yeast for direct inoculation in the fermentation of a fruit or vegetable substrate, e.g. for the...
2018/0179478 WATER-SOLUBLE UNIT DOSE ARTICLE COMPRISING ZWITTERIONIC POLYAMINE
The present disclosure is to a water-soluble unit dose article comprising a detergent composition wherein the detergent contains a zwitterionic polyamine, and...
2018/0179477 WATER-SOLUBLE UNIT DOSE ARTICLE COMPRISING ETHOXYLATED POLYETHYLENEIMINE
The present disclosure is to a water-soluble unit dose article comprising a laundry detergent composition wherein the detergent contains an ethoxylated...
2018/0179476 SOLVENT COMPOSITIONS FOR USE AS HEPTANE REPLACEMENTS
The present disclosure provides, in part, a solvent composition for use as a heptane replacement. The solvent composition may include a first methylated...
2018/0179475 AUTOMATIC DISHWASHING DETERGENT COMPOSITION
A phosphate-free automatic dishwashing cleaning composition comprising a protease wherein the protease is a variant of a parent protease, the parent protease...
2018/0179474 Polymeric Esters of Aromatic Dicarboxylic Acids as Soil Release Agents
The cleaning power of detergents when washing textiles was to be improved. This was accomplished mainly by using polyesters that are accessible from the...
2018/0179473 FABRIC SOFTENER COMPOSITION HAVING IMPROVED DETERGENT SCAVENGER COMPATIBILITY
The present invention relates to fabric softener compositions as well as the methods of making and using same. Such liquid fabric softener compositions...
2018/0179472 FABRIC SOFTENER COMPOSITION HAVING IMPROVED DISPENSING PROPERTIES
The present invention relates to thickened liquid fabric softener compositions as well as the methods of making and using same. Such thickened, structured...
2018/0179471 FABRIC SOFTENER COMPOSITION HAVING IMPROVED FREEZE THAW STABILITY
Fabric softener compositions as well as the methods of making and using same. Such liquid fabric softener compositions comprise a quaternary ammonium ester...
2018/0179469 AUTOMATIC DISHWASHING COMPOSITION
An automatic dishwashing cleaning composition having an alkyl amphocarboxylate surfactant.
2018/0179468 LIQUID SURFACTANT COMPOSITIONS HAVING A MODIFIED OXO-ALCOHOL DERIVATIVE
A liquid surfactant composition can include a C.sub.9-C.sub.20 alkylbenzene sulfonate, a first alcohol ether sulfate (AES), and a nonionic surfactant. The...
2018/0179467 LIQUID SURFACTANT COMPOSITIONS AND ASSOCIATED METHODS
A liquid surfactant composition can include a C.sub.9-C.sub.20 alkylbenzene sulfonate, a nonionic surfactant, and an anionic surfactant. The anionic surfactant...
2018/0179466 Nonionic Surfactant Composition and Surface Cleaning Formulation
The present invention describes a composition of nonionic surfactants comprising a mixture of Guerbet alcohols and natural fatty alcohols with different...
2018/0179465 Articles Fashioned as Candles with Integrated Health, Beauty and Well-Being Functionalities
Candles are provided with special purpose constituent matter to impart hell and well-being properties into the environments in which these articles are...
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