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Patent # Description
2018/0179313 THERMOPLASTIC RESIN COMPOSITION AND MOLDING PRODUCT MADE THEREFROM
A thermoplastic resin composition and a molding product made therefrom are provided in the invention. The thermoplastic resin composition includes a branched...
2018/0179312 THERMOPLASTIC RESIN COMPOSITION AND MOLDING PRODUCT MADE THEREFROM
A thermoplastic resin composition and a molding product made therefrom are provided in the invention. The thermoplastic resin composition includes a branched...
2018/0179311 Ethylenic Polymer and its Use
New ethylene polymers having low levels of long chain branching are disclosed. Films and film layers made form these polymers have good hot tack strength over...
2018/0179310 Spray-Dried Olefin Polymerization Catalyst Compositions and Polymerization Processes for Using the Same
Disclosed herein are spray-dried catalyst compositions including one or more olefin polymerization catalysts and at least one support of an organosilica...
2018/0179309 Single Reactor Production of Polymers in Gas or Slurry Phase
Disclosed are methods for the production of polymers, including random copolymers (RCPs), in single reactor gas or slurry phase polymerization processes, and...
2018/0179308 POLYMERISATION OF ETHYLENE IN THE PRESENCE OF A SILYLCHROMATE BASED CATALYST
The invention relates to a process for the production of high density polyethylene having a density in the range between 945 and 965 kg/m3 by polymerisation of...
2018/0179307 USE OF POLYETHYLENE MATERIALS IN THE PRODUCTION OF STERILISABLE LIQUID CONTAINERS
The present invention relates to the use of a polyethylene material in liquid containers that are sterilisable at a temperature of .gtoreq.100.degree. C....
2018/0179306 PIGMENT DISPERSION LIQUID CONTAINING ORGANIC COLOR PIGMENT AND INFRARED ABSORBING DYE, COLORED RESIN...
The present invention addresses the problem of providing: a pigment dispersion liquid with which an optical filter layer having the functions of both a color...
2018/0179305 IMPROVED METHOD FOR PRODUCING HYDROXYL GROUP-CONTAINING VINYL ETHER POLYMER
A method for producing a hydroxyl group-containing vinyl ether polymer according to the present invention includes: a step of radical polymerizing at least one...
2018/0179304 ALDIMINES AND KETIMINES AS INITIATORS IN HARDENER SYSTEMS AND CORRESPONDING RESIN COMPOSITIONS INTER ALIA FOR...
A hardener system for a synthetic resin composition having free-radical-polymerisable compounds, which includes the following constituents: a) at least one...
2018/0179303 METHOD FOR MANUFACTURING WET RUBBER MASTERBATCH, METHOD FOR MANUFACTURING RUBBER COMPOSITION, AND METHOD FOR...
A problem which is addressed is the provision of a method for manufacturing a wet rubber masterbatch that will serve as raw material for vulcanized rubber...
2018/0179302 Method of Crosslinking of Polysaccharides Using Photoremovable Protecting Groups
The invention discloses a method of preparation of crosslinked materials based on polysaccharides using electromagnetic radiation in an aqueous solution...
2018/0179301 Method of Preparing Oxidized Starch Haemostatic Material
A method of preparing an oxidized starch haemostatic material, including adding a starch raw material to an external circulation pulsatile reactor; switching...
2018/0179300 GENERATION OF BINDING MOLECULES
Provided are methods for efficiently and comprehensively screening antibody repertoires from B cells to obtain and produce molecules with binding...
2018/0179299 TRI-SPECIFIC ANTIBODIES FOR HIV THERAPY
Provided are tri-specific fusion antibodies created to target multiple epitopes of the Human Immunodeficiency Virus (HIV). The fusion antibodies provide...
2018/0179298 METHOD FOR CONTROLLING AFFINITY OF ANTIBODY FOR ANTIGEN, ANTIBODY WHOSE AFFINITY FOR ANTIGEN HAS BEEN ALTERED,...
Disclosed is a method for controlling affinity of an antibody for an antigen, comprising substituting at least 3 amino acid residues of framework region 3...
2018/0179297 TARGETED DELIVERY METHODS AND COMPOSITIONS FOR ANTIHISTAMINES
Products, compositions, and methods for using one or more small particles to facilitate the delivery of one or more antihistamines to a human body are...
2018/0179296 ENGINEERED IMMUNOGLOBULIN HEAVY CHAIN-LIGHT CHAIN PAIRS AND USES THEREOF
The present invention provides heterodimer pairs comprising a first heterodimer and a second heterodimer wherein each heterodimer comprises an immunoglobulin...
2018/0179295 Bispecific Antigen-Binding Constructs Targeting HER2
Provided herein are biparatopic antigen-binding constructs that specifically bind HER2. The biparatopic antigen-binding constructs comprise one antigen-binding...
2018/0179294 TOLL-LIKE RECEPTOR 3 ANTAGONISTS
Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the...
2018/0179293 METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION
In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of...
2018/0179292 RKIP AGONISM IN THE TREATMENT AND PREVENTION OF HEART FAILURE
The present invention relates to a pharmaceutical composition comprising Raf kinase inhibitor protein (RKIP), or a fragment or a variant thereof; or an RKIP...
2018/0179291 Fusion Protein Containing BDNF
Disclosed is a fusion protein containing a brain-derived neurotrophic factor (BDNF). The fusion protein is a fusion protein of BDNF and a specific range of...
2018/0179290 ANTIBODY FORMULATION
Anti-BAFFR antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration...
2018/0179289 USE OF CHIMERIC ANTIGEN RECEPTOR MODIFIED CELLS TO TREAT CANCER
The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR)...
2018/0179288 HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN IL-4 RECEPTOR
The present invention provides nucleic acid molecules that encode antibodies or antigen-binding fragments thereof, which specifically bind human interleukin-4...
2018/0179287 BINDING MOLECULES FOR THE TREATMENT OF CANCER
This invention relates to binding molecules that bind specifically to TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2) and cadherin-17 (CDH17) and...
2018/0179286 MONOCLONAL ANTIBODIES AGAINST HER2
Isolated monoclonal antibodies which bind to human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are...
2018/0179285 BISPECIFIC ANTIBODIES
The present invention relates to engineered heteromultimeric proteins, and more specifically, to methods for producing and purifying heterodimeric proteins,...
2018/0179284 Anti-Inflammatory Polypeptides
This invention concerns anti-inflammatory agents, compositions, and methods for treating inflammatory disorders.
2018/0179283 T CELL RECEPTOR LIKE ANTIBODIES HAVING FINE SPECIFICITY
An antibody capable of binding, with a human major histocompatibility complex (MHC)-restricted specificity, a MHC being complexed with an HLA-restricted...
2018/0179282 TREATMENT OF CANCER BY COMBINED BLOCKADE OF THE PD-1 AND CXCR4 SIGNALING PATHWAYS
This disclosure provides a method for treating a subject afflicted with a cancer comprising administering to the subject a combination of therapeutically...
2018/0179281 COSTIMULATORY B7-H1 IN RENAL CELL CARCINOMA PATIENTS: INDICATOR OF TUMOR AGGRESSIVENESS AND POTENTIAL...
The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of...
2018/0179280 BLOCKADE OF CD7 EXPRESSION AND CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY OF T-CELL MALIGNANCIES
The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods...
2018/0179279 METHODS AND COMPOSITIONS FOR TREATING FIBROTIC DISEASES
The invention provides methods and compositions for the prevention or treatment of fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic...
2018/0179278 Methods for Treating Inflammatory Disorders or Cancer Metastasis by Administering Antibodies to Connexin 43...
Methods for identifying compounds that positively regulate connexin 43 hemichannels.
2018/0179277 Compositions and Methods including a Recombinant Human MAB that Promotes CNS Remyelination
Antibodies, and particularly human antibodies, are disclosed that demonstrate activity in the treatment of demyelinating diseases as well as other diseases of...
2018/0179276 NOVEL COMPOUNDS CAPABLE OF ANTAGONIZING ISLET AMYLOID POLYPEPTIDE (IAPP) INDUCED BETA-CELL DAMAGE AND IMPAIRED...
Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as...
2018/0179275 ANTI-CCL2 ANTIBODIES FOR TREATMENT OF SCLERODERMA
The present invention provides, among other things, improved anti-CCL2 antibodies characterized with high affinity, potency, tissue selectivity and/or epitope...
2018/0179274 PROTEINS COMPRISING A MUTATED LAIR-1 FRAGMENT AND USES THEREOF
The present invention provides a protein comprising a mutated LAIR-1 fragment, which broadly binds to erythrocytes infected with Plasmodium falciparum. The...
2018/0179273 MONOCLONAL ANTI-ALPHA-SYNUCLEIN ANTIBODIES FOR PREVENTING TAU AGGREGATION
The invention relates to a novel use of monoclonal anti-alpha-synuclein antibodies. The antibodies can be used to prevent tau aggregation and thereby treating...
2018/0179272 NOVEL ASSAY TO DETECT HUMAN PERIOSTIN
This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients...
2018/0179271 Agents, Uses and Methods for the Treatment of Synucleinopathy
The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's...
2018/0179270 Agents, Uses and Methods for the Treatment of Synucleinopathy
The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's...
2018/0179269 NUCLEIC ACID AND CORRESPONDING PROTEIN NAMED 158P1D7 USEFUL IN THE TREATMENT AND DETECTION OF BLADDER AND OTHER...
The invention described herein relates to novel nucleic acid sequences and their encoded proteins, referred to as 158P1D7 and variants thereof, and to...
2018/0179268 METHODS AND COMPOSITIONS FOR TREATING CELIAC DISEASE
The invention features the treatment of gastrointestinal disorders associated with an innate immune response triggered by alpha amylase inhibitor CM3, alpha...
2018/0179267 ANTI-STAPHYLOCOCCUS AUREUS ANTIBODY COMBINATION PREPARATION
An anti-Staphylococcus aureus antibody combination preparation comprising a) a toxin cross-neutralizing antibody comprising at least one polyspecific binding...
2018/0179266 IMMUNOGLOBULIN SINGLE VARIABLE DOMAIN ANTIBODY AGAINST RSV PREFUSION F PROTEIN
The present invention relates to immunoglobulin single variable domains (ISVDs) that are directed against respiratory syncytial virus (RSV). More specifically,...
2018/0179265 ENGINEERED HUMAN ANTI-AAV ANTIBODIES AND USES THEREOF
A method for generating engineered human anti-AAV antibodies is described. Also described are compositions, panels and arrays containing these antibodies and...
2018/0179264 SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence...
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