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Patent # Description
2018/0177800 COMPOSITION FOR PERCUTANEOUS ABSORPTION
Provided is a composition for percutaneous absorption containing testosterone and one or more organic solvents selected from the group consisting of propylene...
2018/0177799 Compositions and Methods for Muscle Regeneration Using Prostaglandin E2
Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or...
2018/0177798 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or...
2018/0177797 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS
Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions including a ...
2018/0177796 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS
Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions including a ...
2018/0177795 ISOQUINOLIDINOBENZODIAZEPINE (IQB)-1(CHLOROMETHYL)-2,3-DIHYDRO-1H-BENZO[E]INDOLE (CBI) DIMERS
Provided herein are isoquinolidinobenzodiazepine (IQB)-1(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) dimers, antibody-drug conjugates comprising them and...
2018/0177794 METHODS OF TREATMENT AND PHARMACEUTICAL COMPOSITIONS USING AN SGLT-2 INHIBITOR AND A NEUROLEPTIC AGENT
The invention relates to methods for preventing, slowing the progression of, delaying or treating metabolic disorders induced in patients by the treatment with...
2018/0177793 CYCLIC AMINES
The present invention is directed to novel cyclic amines which inhibit the P2X7 receptor.
2018/0177792 COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH RTK MUTANT CELLS
Disclosed herein are compositions and methods for treating cancer patients who have been previously treated with one or more chemotherapeutic agents and have...
2018/0177791 COMBINATION THERAPIES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
2018/0177790 COMBINATION THERAPIES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
2018/0177789 COMBINATION THERAPIES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
2018/0177788 THERAPEUTIC COMPOSITIONS, COMBINATIONS, AND METHODS OF USE
This invention relates to methods comprising administering a FAK inhibitor and an immunotherapeutic agent such as anti-PD-1 or anti-PD-L1; that are useful in...
2018/0177787 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE AND THERAPEUTIC USES THEREOF
Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole...
2018/0177786 MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER
A method of treating prostate cancer in a subject with biochemically recurrent prostate cancer is provided. The method includes administering to a subject in...
2018/0177785 Method of Making Sustained Release Microparticles
Various embodiments of a method of preparing sustained release microparticles are described. In one embodiment, the method includes the steps of forming a...
2018/0177784 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
Disclosed are compounds of Formula (I'), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The...
2018/0177783 COMBINATION THERAPY USING BELINOSTAT AND PRALATREXATE TO TREAT LYMPHOMA
The present invention relates to compositions and methods for treating lymphoma in a subject in need thereof, said methods comprising administering to the...
2018/0177782 NOVEL USES
The invention relates to the administration of inhibitors of phosphodiesterase 1 (PDE1) for the treatment of diseases or disorders characterized by disruption...
2018/0177781 NOVEL CRYSTALLINE FORMS
The present invention relates to novel crystalline polymorphic forms of 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-2-methyl-4H-pyrid- ...
2018/0177780 PYRIDAZINONE COMPOUNDS AND THEIR USE AS DAAO INHIBITORS
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R.sup.1 and R.sup.2 are as defined in the...
2018/0177779 Methods for Treating HCV
The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as...
2018/0177778 Methods for Treating HCV
The present invention features interferon-free therapies for treating Hepatitis C Virus (HCV) genotypes 1b, 2, 3 or 4. In one aspect, the therapies comprises...
2018/0177777 FORMULATIONS FOR MITIGATING OPIOID OVERDOSE AND METHODS OF MAKING AND USING THE SAME
The presently disclosed subject matter is directed to opioid antagonist formulations for use in mitigating opioid abuse and/or overdose in a subject....
2018/0177776 COMPOSITIONS FOR THE TREATMENT OF CANCER AND USES THEREOF
The invention pertains to compositions comprising inhibitors of PI3K, AKT and/or mTOR, one or more 4-quinolinemethanols and a pharmaceutically acceptable...
2018/0177775 COMPOSITIONS AND METHODS FOR TREATMENT RELATED TO FALL AND FALL FREQUENCY IN NEURODEGENERATIVE DISEASES
The present disclosure provides methods and compositions for treating fall-related symptoms in patients with neurodegenerative diseases such as Parkinson's...
2018/0177774 TOPICAL RETINOID COMPOSITIONS
The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active...
2018/0177773 USE OF ANTI-CONNEXIN AGENTS FOR ENHANCING THE THERAPEUTIC EFFECT OF ACETYLCHOLINESTERASE INHIBITORS
This invention relates to improvements in therapeutic neurological and neuropsychic treatments using acetylcholinesterase inhibitors. More specifically, the...
2018/0177772 METHODS OF TREATING GLIOBLASTOMA MULTIFORME USING IBUDILAST
Compositions and methods for treating glioblastoma or recurrent glioblastoma and its associated symptoms by administration of ibudilast ...
2018/0177771 BIOMARKERS FOR NANOPARTICLE COMPOSITIONS
The present invention provides methods and compositions for treating a hyperplasia (such as cancer, restenosis, or pulmonary hypertension) by administering a...
2018/0177770 METHODS OF TREATING EPITHELIOID CELL TUMORS
The present invention provides methods and compositions for treating epithelioid cell tumors (such as a PEComa) by administering a composition comprising...
2018/0177769 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase
The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are...
2018/0177768 METHODS AND COMPOSITIONS TO TREAT CANCER
Embodiments provided herein relate to methods and compositions for treating cancer. Some embodiments include treating lung cancers and renal cancers.
2018/0177767 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME
Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of...
2018/0177766 THERAPEUTIC AGENT FOR NEUROTROPHIC KERATOPATHY
Provided are a novel pharmaceutical use of PPAR.delta. agonist such as a therapeutic agent for neurotrophic keratopathy, an improving agent for decrease of...
2018/0177765 Compositions and Methods employing Wolbachia FtsZ as a target for Albendazole sulfone
Compositions and Methods are described in which Albendazole sulfone binds to Wolbachia FtsZ providing anti filarial activity.
2018/0177764 TREATMENT OF CARDIAC DISORDERS BY BLOCKING SK4 POTASSIUM CHANNEL
Methods of inducing bradycardia (slowing a heart rate) in a subject in need thereof, treating a medical condition in which inducing bradycardia (slowing a...
2018/0177763 SMALL MOLECULES THAT MIMIC OR ANTAGONIZE ACTIONS OF GRANULOCYTE COLONY-STIMULATING-FACTOR (G-CSF)
Described herein are compound for the modulation of the G-CSF receptor. The compounds may act as agonists, antagonists, and/or mixed or partial ...
2018/0177762 ANTI-DANDRUFF COMPOSITIONS COMPRISING A SPIROFURANONE LACTAM TETRAMIC ACID DERIVATIVE
Anti-Dandruff Agents A novel anti-dandruff composition comprising spirofuranone-lactam tetramic acid or derivatives thereof, and optionally at least one...
2018/0177761 AMINO COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS
Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or...
2018/0177760 COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE...
Described are compositions that may be orally administered that comprise a bioreversible derivative of hydroxy N-substituted-2-aminotetralin or an enantiomer...
2018/0177759 COMBINATION OF AN ANTIANDROGEN WITH A VITAMIN K ANTAGONIST OR WITH A GAMMA-GLUTAMYL CARBOXYLASE INHIBITOR FOR...
The present invention relates to the combination of an antiandrogen with a vitamin K antagonist or with a .gamma.-glutamyl carboxylase inhibitor for use in the...
2018/0177758 COMPOUNDS FOR TREATMENT OF ANGIOGENESIS-MEDIATED DISEASES
Synthetic cremastranone and cremastranone analogs are disclosed. Additionally, methods for synthesizing cremastranone and cremastranone analogs are disclosed....
2018/0177757 ULTRAPURE TETRAHYDROCANNABINOL-11-OIC ACIDS
This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use...
2018/0177756 A 19-144, A2-73 AND CERTAIN ANTICHOLINESTERASE INHIBITOR COMPOSITIONS AND METHOD FOR ANTI-SEIZURE THERAPY
This invention concerns a dosage form comprising a therapeutically effective amount of A19-144 or A2-73 and a therapeutically effective amount of at least one...
2018/0177755 METHODS OF TREATING UROLOGICAL DISORDERS USING SARMs
The present invention is directed to methods of treating, preventing, suppressing and/or inhibiting urological disorders such as urinary incontinence including...
2018/0177754 COMPOSITIONS FOR USE IN TREATING PULMONARY ARTERIAL HYPERTENSION
The present disclosure provides methods of treating pulmonary arterial hypertension (PAH) in a subject in need thereof. Compositions for use in these methods...
2018/0177753 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT
A method of management of migraine symptom reduction and/or management and/or prophylaxis is disclosed using 3-hydroxybutyate glycerides is disclosed.
2018/0177752 PHARMACEUTICAL SUSPENSIONS CONTAINING DRUG PARTICLES, DEVICES FOR THEIR ADMINISTRATION, AND METHODS OF THEIR USE
The invention features a pharmaceutical suspension containing drug particles, a drug delivery device anchored in the mouth for continuously administering the...
2018/0177751 VALPROIC ACID FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH EXCESS FIBRIN...
There is herein provided valproic acid, or a pharmaceutically acceptable salt, thereof, for use in treating or preventing a pathological condition associated...
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