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Patent # Description
2018/0177750 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ENHANCER OF ZESTE HOMOLOG 2 POLYPEPTIDE
The present disclosure relates to bifunctional compounds, which find utility as modulators of enhancer of zeste homolog 2 (target protein). In particular, the...
2018/0177749 USE OF CYP EXPRESSION TO DIRECT THERAPEUTIC INTERVENTION IN CANCER
Certain embodiments of the invention provide a method for identifying a cancer cell that is sensitive to a biguanide compound or other CYP epoxygenase...
2018/0177748 COMBINATION MEDICATION FOR NEURO-DEGENERATIVE DISEASES
A pharmaceutical composition containing a benzhydrylsulfinylacetamide antidepressant, and either or both of an SSRI uptake inhibitor and/or a stimulating...
2018/0177746 ALKOXY COMPOUNDS FOR DISEASE TREATMENT
The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and...
2018/0177745 Application Of R-ketamine And Salt Thereof As Pharmaceuticals
Provided is a novel compound having rapid and long-lasting therapeutic effects on diseases exhibiting depressive symptoms. Specifically, provided are an agent...
2018/0177744 METHOD OF TREATING PAIN AND DEPRESSION USING A HYBRID MIXTURE OF S-KETAMINE AND R-KETAMINE
A method of administering a drug formulation comprising intranasally administering a nanoparticle composition of an effective amount of hybridized esketamine...
2018/0177743 METHOD OF TREATING PAIN USING RACEMIC MIXTURE OF S-KETAMINE AND R-KETAMINE
A method of administering a drug formulation comprising intranasally administering a nanoparticle composition of an effective amount of a subanesthetic racemic...
2018/0177742 NON-AQUEOUS PATCH COMPRISING LIDOCAINE
The present invention relates to non-aqueous patches containing lidocaine.
2018/0177741 Thin Film With Non-Self-Aggregating Uniform Heterogeneity And Drug Delivery Systems Made Therefrom
The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films...
2018/0177740 NON-NATURAL FIBER OR FILAMENT WITH HERBAL RESIDUE AND METHOD OF MAKING THE SAME
The non-natural fiber or filament composition comprises an herbal masterbatch, a base polymer powder or a polymer, and one or more additives such as coupling...
2018/0177739 DELIVERY OF DRUG NANOPARTICLES AND METHODS OF USE THEREOF
Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a...
2018/0177738 STABILIZED POLYMERIC NANOCAPSULES, DISPERSIONS COMPRISING THE NANOCAPSULES, AND METHODS FOR THE TREATMENT OF...
A nanocapsule includes a liquid hydrophobic care including an essential oil, and a shell encapsulating the core. The shell includes a copolymer having...
2018/0177737 INSTRUMENT FOR SKIN TREATMENT
An apparatus configured to result in a penetration of one or more gasses into a dermis of biological skin, wherein the apparatus includes a fluid reservoir...
2018/0177736 Cell Lines and Their Use in Encapsulated Cell Biodelivery
The present invention relates to generation of cell lines expressing recombinant proteins for use in naked and encapsulated cell biodelivery of secreted...
2018/0177735 Stable Pharmaceutical Composition Of Phytonadione And A Novel Process For Preparation Thereof
The present invention is related to a process of preparing a stable pharmaceutical composition of phytonadione comprising the steps of a preparing dispersion...
2018/0177734 PHARMACEUTICAL FORMULATIONS COMPRISING TENOFOVIR AND EMTRICITABINE
The invention provides a solid oral dosage form comprising tenofovir alafenamide or a pharmaceutically acceptable salt thereof, and emtricitabine or a...
2018/0177733 RAPID DISSOLVE TABLET COMPOSITIONS FOR VAGINAL ADMINISTRATION
Disclosed herein are pharmaceutically acceptable rapid dissolve vaginal tablet compositions comprising one or more active pharmaceutical ingredients suitable...
2018/0177732 OXIDATION-STABILIZED TAMPER-RESISTANT DOSAGE FORM
A thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising a pharmacologically active ingredient...
2018/0177731 Composite Preparation of Mosapride and Rabeprazole
The present invention relates to a composite preparation with various dosage forms comprising mosapride and rabeprazole. The composite preparation prepared...
2018/0177730 MICROSPHERES CONTAINING ANTHELMINTIC MACROCYCLIC LACTONES
Disclosed are microspheres containing 1% to 20% by weight of milbemycin, avermectin or a derivative thereof, 50% to 95% by weight of a fat, a wax or a mixture...
2018/0177729 G PROTEIN-COUPLED RECEPTORS INCORPORATED INTO REHYDRATED POLYMER VESICLES RETAIN FUNCTIONALITY
A G Protein Coupled Receptor (GPCR) is incorporated in polymeric giant unilamellar protein vesicles (pGUPs). By utilizing an agarose rehydration technique, the...
2018/0177728 NANOPARTICLES
The invention provides a (drug-containing) lipid nanoparticle with: (i) at least one phospholipid; (ii) at least one lysolipid; and (iii) at least one...
2018/0177727 USE OF EXOSOMES FOR THE TREATMENT OF DISEASE
The present invention provides lipid-based nanoparticles (e.g., liposomes or exosomes) having CD47 on their surface and comprising a therapeutic agent (e.g., a...
2018/0177726 USE OF LIPOSOMES IN A CARRIER COMPRISING A CONTINUOUS HYDROPHOBIC PHASE AS A VEHICLE FOR CANCER TREATMENT
The invention compositions comprising a continuous hydrophobic phase and liposomes as a vehicle for delivery of an antigen capable of inducing a cytotoxic T...
2018/0177725 CELL MEMBRANE-FORMED NANOSCALE VESICLES AND METHODS OF USING THEREOF
The present disclosure provides vesicle composition comprising a cell membrane and an agent for the treatment and identification of diseases. Methods of...
2018/0177724 SITE-TARGETED NANO-LIPOSOMAL NITROGLYCERIN THERAPEUTICS
The disclosure provides for nanoliposomal formulations comprising nitroglycerin, methods of making the formulations, and methods of use thereof.
2018/0177723 COMPOSITION AND METHOD OF PRODUCING NANOFORMULATION OF WATER INSOLUBLE BIOACTIVES IN AQUEOUS BASE
Exemplary embodiment of the present disclosure are directed towards a stable nanodispersion comprising an aqueous dispersion medium, a dispersed phase, a...
2018/0177722 Coenzyme Q10 Aerosol
The present invention provides a formulation of Coenzyme Q10 that can be re-dispersed from a stable dry powder to formulation to yield a nano dispersion that...
2018/0177721 Manufacture of Pharmaceutical Compositions
The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active...
2018/0177720 Chewable Composition and Delivery Pouch
A chewable delivery pouch including a chewable composition containing cannabis. An interior volume of the chewable pouch is filled with a composition having a...
2018/0177719 PHARMACEUTICAL COMPOSITIONS
By individually metering and dispensing specific volumes and/or weights of each component of a dosage, an amount of the components for each dose is secured...
2018/0177718 IMPLANT FOR TREATMENT OF AN OCULAR CONDITION
The present disclosure relates to the field of pharmaceutical compositions, ocular implants, and systems and methods for treating an ocular condition. In...
2018/0177717 IMPLANTABLE POLYMERIC DEVICE FOR SUSTAINED RELEASE OF BUPRENORPHINE
The present invention provides compositions, methods, and kits for treatment of opiate addiction and pain. The invention provides a biocompatible nonerodible...
2018/0177716 TRANSPLANTATION IMPLANT FOR PROMOTING HAIR GROWTH
The present disclosure relates to a transplantation implant that includes stem cells having an ability of secreting a cytokine that having a hair-growing...
2018/0177715 NATURAL BASE TEETH WHITENING GEL CONTAINING NO PEROXYDE
The invention relates to a teeth whitening gel containing no peroxidizing agent or petrochemical by-products, and comprising a combination of a whitening agent...
2018/0177714 A HIGHLY CONCENTRATED SEAWATER MINERAL EXTRACT AND USES THEREOF
A seawater mineral extract derived from seawater having a salinity of from 3.4% Brix to 3.6% Brix, wherein the seawater mineral extract comprises a mineral...
2018/0177713 AGENT AND METHOD FOR THE TEMPORARY SHAPING OF KERATINOUS FIBERS
Agents and compositions and methods are provided for the temporary shaping of keratinous fibers. In an exemplary embodiment, cosmetic composition includes from...
2018/0177712 COSMETIC COMPOSITIONS WHICH ARE HOMOGENOUS IN THE BULK AND CAPABLE OF FORMING A MULTILAYER STRUCTURE AFTER...
Cosmetic compositions capable of forming a multilayer structure after application to a keratinous material are provided, as well as methods of applying such...
2018/0177711 COSMETIC COMPOSITIONS WHICH ARE HOMOGENOUS IN THE BULK AND CAPABLE OF FORMING A MULTILAYER STRUCTURE AFTER...
Cosmetic compositions capable of forming a multilayer structure after application to a keratinous material are provided, as well as methods of applying such...
2018/0177710 GEL POLISH COMPOSITION FORMING A NAIL GEL FILM ON A KERATINOUS MATERIAL OF MAMMALS AND THE METHOD OF USING THEREOF
A gel polish composition forming a nail gel film on a keratinous material of mammals comprises a film-forming polymer selected from the group consisting of...
2018/0177709 Oral Care Whitening Compositions
Described herein are whitening compositions comprised of a peroxide component, and an adhesion system, which effectively provide whitening using a remarkably...
2018/0177708 COSMETIC COMPOSITIONS FOR TREATING KERATINOUS SUBSTRATES
Disclosed are compositions for treating and cleansing keratinous substrates, comprising: a polysaccharide; a cationic polymer in an amount of at least 0.1% by...
2018/0177707 METHOD OF PREPARING A COMPOSITION BASED ON HYALURONIC ACID
The invention relates to a method of preparing a composition, the composition comprising a crosslinked first polymer, optionally a second polymer, which may be...
2018/0177706 COMPOSITIONS CONTAINING HYALURONIC ACID AND SYNERGISTIC ANTI-HYALURONIDASE ACTIVES
Compositions comprising a hyaluronic acid adjuvant system comprising hyaluronic acid, purple rice extract and dipotassium glycyrrhizate, present together in...
2018/0177705 ANESTHETIC MOISTURIZING BODY WAX
The present invention relates to a cosmetic composition added to the body wax wherein, the cosmetic composition is made from naturally ingredients that has...
2018/0177704 COMPOSITIONS COMPRISING FRUIT ENZYME SUITABLE FOR ALTERING THE COLOR OF HAIR
Provided are hair color-altering compositions which comprise a fruit enzyme selected from the group consisting of bromelain, papain, and combinations thereof;...
2018/0177703 Niacinamide Mononucleotide Formulations For Skin Aging
Topical compositions including niacinamide mononucleotide to improve the appearance of aging skin and to prevent and treat skin aging; and methods of use of...
2018/0177702 COSMETIC COMPOSITION HAVING HIGH DOSAGE FORM STABILITY
The present invention relates to a cosmetic composition using a mannosylerythritol lipid, which is a kind of glycolipid, as a stabilizer in order to prevent...
2018/0177701 HAIR REMOVAL METHODS AND COMPOSITIONS
Compositions and methods for selectively and permanently removing hair from the body. The compositions are formulated to be topically applied upon discrete...
2018/0177700 HAIR REMOVAL COMPOSITIONS AND METHODS
Compositions and methods for selectively and permanently removing hair from the body. The compositions are formulated to be topically applied upon discrete...
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