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Patent # Description
2018/0200229 TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are...
2018/0200228 Use of Chloroquine and Clemizole Compounds for Treatment of Inflammatory and Cancerous Conditions
Disclosed herein are methods for use of R-chloroquine or clemizole or combinations of R-chloroquine and clemizole for the treatment of a subject in need...
2018/0200227 Use of 2-(5S-methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetamide in the Treatment of Seizures
Use of 2-(55-Methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetamide or its pharmaceutically acceptable salt in manufacture of a medicament for prophylaxis and...
2018/0200226 COMPOSITIONS AND METHODS OF USE OF ANTIBACTERIAL DRUG COMBINATIONS
The present disclosure encompasses antibacterial compositions and methods of treating bacterial infections caused by resistant bacteria.
2018/0200225 HYDRAZONE MODULATORS OF CANNABINOID RECEPTORS
Hydrazone compounds which modulate cannabinoid receptors are presented. Pharmaceutical compositions containing these compounds, methods of using these...
2018/0200224 Antiviral Activity from Medicinal Mushrooms and Their Active Constituents
Compounds having unique antiviral properties found in mushroom mycelium and their analogs are extracted, concentrated, isolated or manufactured to create...
2018/0200223 APPLICATION OF NARINGENIN AND NARINGIN IN TUMOR RADIOTHERAPY
The present invention provides applications of a small molecular flavonoid compound in preparing a medication for sensitizing/synergizing tumor radiation...
2018/0200221 BENZONATATE MODIFIED RELEASE SOLID TABLETS AND CAPSULES
A modified release benzonatate solid tablet or capsule is described which comprises a benzonatate adsorbate in a matrix with a sufficient amount of one or more...
2018/0200220 PROPHYLAXIS AND MITIGATION OF MIGRAINE HEADACHES USING KETOGENIC MEDIUM CHAIN TRIGLYCERIDES, KETONE ESTERS, AND...
The invention provides methods of reducing the frequency of migraine onset in a migraineur, reducing migraine symptoms experienced by a migraineur, augmenting...
2018/0200219 PHEROMONE COMPOSITIONS AND USES THEREOF
The present invention relates to a composition of less than or equal to about 1% of pheromones useful to treat or prevent a behavioral stress problem of a...
2018/0200218 INHIBITORS FOR TREATING DISEASES CHARACTERIZED BY ATRIAL ENLARGEMENT OR REMODELING
The present invention relates to the NEP inhibitor pro-drug N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylb- utanoic acid ethyl ester,...
2018/0200217 COMPOSITIONS FOR USE IN TREATING INFLAMMATORY BOWEL DISEASES AND INTESTINAL COLITIS
Compositions for use in treating and/or alleviating a symptom of inflammatory bowel disease, colitis, and/or enterocolitis in a subject in need thereof are...
2018/0200216 Compositions for Mitigating Head Trauma
A method for mitigating the effects of traumatic brain injury in an individual comprising is disclosed. The method includes administering an amount of a...
2018/0200215 Controlled Release Dosage Form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in...
2018/0200214 Controlled Release Dosage Form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in...
2018/0200213 METHODS OF TARGETING APE/REF-1 TO INHIBIT HYPOXIA SIGNALING GENES
Methods for targeting apurinic/apyrimidinic endonuclease1/redox effector factor 1 (APE1/Ref-1) are disclosed. More particularly, methods for inhibiting...
2018/0200212 SYSTEMS AND METHODS FOR TREATING VITILIGO
The present invention generally relates to systems and methods for treating vitiligo. In one set of embodiments, the present invention comprises a composition...
2018/0200211 [2.2.2] BICYCLIC DERIVATIVES AND METHODS OF USE
Administration of a salt of bi-cyclo [2.2.2] octane-2-carbonic acid reduces dysphoria in dysphoric subjects, ameliorates ethanol craving in alcoholics, reduces...
2018/0200210 METHOD OF ADMINISTRATION OF GAMMA HYDROXYBUTYRATE WITH MONOCARBOXYLATE TRANSPORTERS
One embodiment of the present invention is to improve the safety and efficacy of the administration of GHB or a salt thereof to a patient. It has been...
2018/0200209 ENHANCED BIOAVAILABILITY OF N-(2,6-BIS(1-METHYLETHYL)PHENYL)-N'-((1-(4-(DIMETHYLAMINO)-PHENYL)CYCLOPE- ...
Methods for enhancing the bioavailability of N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(4-(dimethylamino)phenyl)cyclopen- tyl)-methyl)urea hydrochloride (ATR-101)...
2018/0200208 COMPOSITIONS FOR IMPROVING OR MAINTAINING MYOCARDIAL FUNCTION
Compositions comprising melatonin or derivatives thereof together with coenzyme Q10 and/or alpha-lipoic are provided for oral administration to act as a...
2018/0200207 5-HYDROXYTRYPTAMINE 1B RECEPTOR-STIMULATING AGENT FOR USE AS A PROMOTER OF SATELLITE CELLS SELF-RENEWAL AND/OR...
The present invention relates to the field of muscle regeneration, and more particularly to the replenishment of the in vivo muscle stem cells pool. It more...
2018/0200206 TRANSPAPILLARY METHODS AND COMPOSITIONS FOR TREATING BREAST DISORDERS
Methods and treatments are taught for the treatment of breast disorders, including proliferative breast disease, breast cancer, and increased breast density....
2018/0200205 Treatment of Irritable Bowel Syndrome
A method of treating irritable bowel syndrome in a patient in need thereof by administering to said patient a pharmaceutically effective amount of tapentadol.
2018/0200204 CANCER PROGNOSIS AND THERAPY BASED ON SYNTHEIC LETHALITY
Systems and methods for identifying synthetic lethal (SL) and synthetic dosage lethal (SDL) interactions and networks are provided. Further provided are...
2018/0200203 CONTROLLED RELEASE DELIVERY SYSTEM FOR NASAL APPLICATION OF NEUROTRANSMITTERS
This invention relates to a galenical gel formulation for nasal administration of neurotransmitters/neuromodulators such as dopamine, serotonin or pregnenolone...
2018/0200202 PRE-FILLED SYRINGE
The invention relates to a pre-filled syringe, an auto-injector device comprising such pre-filled syringe, a method of administering a pharmaceutical...
2018/0200201 SOLID DISPERSIONS OF COENZYME Q10
The invention relates to a solid dispersion comprising Coenzyme Q.sub.10 and a phospholipid, in the presence of a cellulosic derivative and/or a polymeric...
2018/0200200 PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF
The present invention relates to the fields of medicine and cancer treatment. The invention more specifically relates to the use of a panicein or a derivative...
2018/0200199 PATCH FOR TREATING DERMATOPHYTOSIS
A patch for a nail for treating dermatophytosis which includes a pressure-sensitive adhesive layer containing an acrylic-based pressure-sensitive adhesive and...
2018/0200198 PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERMEATION
Pharmaceutical compositions having enhanced active component permeation properties are described.
2018/0200197 NANOCAPSULE FOR DELIVERY OF LIPOPHILIC COMPOUND AND PROCESS OF PREPARATION THEREOF
The invention relates to biocompatible polysaccharide-based nanocapsule templated on oil core of diameter not exceeding 1 .mu.m, stabilized without low...
2018/0200196 Modular Particulars for Immunotherapy
Nanoparticulate compositions are disclosed. The nanoparticulate compositions typically include at least one, preferably two or more, active agent(s), one of...
2018/0200195 STABILIZED HIGH DRUG LOAD NANOCARRIERS, METHODS FOR THEIR PREPARATION AND USE THEREOF
The present invention relates to generally to pharmaceutical formulations. Particularly, the present invention relates to a drug nanocarrier that is stabilized...
2018/0200194 DECOY NANOPARTICLES TO DISRUPT CANCER CELL-STROMAL CELL NETWORKS
The present invention relates to compositions and methods for disrupting cancer stromal cell networks using synthetic nanoparticles coated with plasma membranes.
2018/0200193 PEDIATRIC FORMULATION
The present invention relates to pediatric drug formulation. Especially, this invention relates to the manufacturing of granules comprising a core comprising a...
2018/0200192 FORMULATIONS OF N-ACETYLCYSTEINE AND USES THEREOF
Disclosed herein are compositions comprising a first compound that is N-acetylcysteine or a salt thereof, optionally a second compound that is a...
2018/0200191 Multi Component Pill and Method(s) of Use
A multi component pill and method(s) of use are described. The multi component pill comprises disparate nutrient or vitamin components in a unitary pill....
2018/0200190 MULTIPLE PILL ABUSE-RESISTANT IMMEDIATE RELEASE SOLID DOSAGE FORM OF HYDROCODONE
An immediate-release, abuse-resistant solid dosage form comprising melt extrudates of a mixture of: hydrocodone or its pharmaceutically acceptable salt,...
2018/0200189 METHOD OF INDUCING SATIETY
The invention provides a method of inducing satiety in a subject comprising a step of orally administering a composition comprising an effective amount of a...
2018/0200188 Protease Cleavage Site Peptides as an HIV Vaccine
Instead of generating immune responses to several HIV proteins and risk over activating more CD4+ T cells (easy targets for HIV-1 infection) as current...
2018/0200187 LIPOSOME LOADING
Provided herein is technology relating to incorporation of drugs into liposomes and particularly, but not exclusively, to methods for incorporating drugs into...
2018/0200186 COMPOSITIONS AND METHODS FOR TREATING LUNG DISEASES AND LUNG INJURY
Compositions comprising an RNA interference (RNAi) compound complexed to or encapsulated by lipid particles are provided. The lipid particle is a lipid...
2018/0200185 IMPLANTS AND CONSTRUCTS INCLUDING HOLLOW FIBERS
Hollow fiber drug delivery devices are described. Device can contain structural or solid fibers. Fabric can be formed by fibers being interwoven or joined to...
2018/0200184 RAPAMYCIN FOR THE TREATMENT OF LYMPHANGIOLEIOMYOMATOSIS
The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods...
2018/0200183 2' FLUORO-MODIFIED RNAs AS IMMUNOSTIMULATORS
Methods of inhibiting the growth of cells or inducing cell death by contacting the cells with or introducing into the cells a composition including a 5'...
2018/0200182 TRANSMUCOSAL DRUG DELIVERY DEVICES FOR USE IN CHRONIC PAIN RELIEF
Provided herein are methods for treating chronic pain by administering low doses of buprenorphine twice daily (or once daily) via a transmucosal drug delivery...
2018/0200181 COMPOSITION FOR BODY SLIMMING AND SKIN CARE AND PREPARATION METHOD THEREOF
Disclosed is a composition which has the functions of weight loss and skin care, comprising the following raw materials in parts by weight: 5-10 parts of oats,...
2018/0200180 MAGNOLIA BARK EXTRACT AS A HYDROPHOBIC LIGAND FOR PREFERENTIAL REMOVAL OF GRAM NEGATIVE BACTERIA FROM THE ORAL...
The present disclosure relates generally to oral compositions and methods for freshening breath and oral cleansing, and more particularly, to oral compositions...
2018/0200179 FAT STEM CELL ATTRACTANT-CONTAINING AGENT FOR IMPROVING SKIN LOOSENESS OR AGING CAUSED BY DERMAL CAVITATION
The purpose of the present invention is to provide an agent for improving skin looseness or aging caused by dermal cavitation. By attracting fat stem cells...
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