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Patent # Description
2018/0265486 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS
Novel 1-oxa-4-azonium cyclohexane salts are described. These compounds can be used as structure directing agents, and they overcome many of the typical...
2018/0265485 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS
Novel 1-oxa-4-azonium cyclohexane salts are described. These compounds can be used as structure directing agents, and they overcome many of the typical...
2018/0265484 HEPATITIS B CORE PROTEIN MODULATORS
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of...
2018/0265483 MICROBIOCIDAL OXADIAZOLE DERIVATIVES
Compounds of the formula (I) wherein, the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides. ##STR00001##
2018/0265482 METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF
Provided here are methods of manufacture of viloxazine and its various salts, as well as viloxazine-related compounds, such as novel intermediate reaction...
2018/0265481 METHOD FOR PREPARATION OF CERTAIN 1,5 DISUBSTITUTED TETRAZOLES
The invention discloses a method for the preparation of certain 1,5 disubstituted tetrazole and similar compounds starting from certain thioacetamides, which...
2018/0265480 METHOD FOR PREPARING CONTRAST AGENT PRECURSOR
A method for preparing a contrast agent precursor is revealed. The method includes several steps. First dissolve di-tert-butyl ...
2018/0265479 FATTY ACID SYNTHASE INHIBITORS AND METHODS OF USE
The present disclosure provides for methods of treating cancer in a subject. In certain embodiments, the method comprises administering a therapeutically...
2018/0265478 PRMT1 INHIBITORS AND USES THEREOF
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein...
2018/0265477 SPIRO COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME
The present specification provides a spiro structured compound and an organic light emitting device including the same.
2018/0265476 CONDENSED RING DERIVATIVE, AND PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Disclosed are a condensed ring derivative, and a preparation method, an intermediate, a pharmaceutical composition and a use thereof. The condensed ring...
2018/0265475 HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS
The present invention provides halogenated quinoline derivatives, such as compounds of Formula (I) or (I'), and pharmaceutically acceptable salts thereof, and...
2018/0265474 POLYMORPHIC COMPOUNDS AND USES THEREOF
The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions, in which aldehyde...
2018/0265473 CRYSTAL FORMS OF BEDAQUILINE FUMARATE AND PREPARATION METHODS THEREFOR
Provided are crystal forms I, II, and III of bedaquiline fumarate, and preparation methods thereof. The crystal forms have high purity, excellent...
2018/0265472 PROCESS FOR PREPARING ARIPIPRAZOLE LAUROXIL AND INTERMEDIATES THEREOF
A process for preparing a compound of formula I': ##STR00001## or a pharmaceutically acceptable salt thereof, in which R represents optionally substituted or...
2018/0265471 4-(METHYLAMINOPHENOXY)PYRDIN-3-YL-BENZAMIDE DERIVATIVES FOR TREATING CANCER
The present invention provides a novel compound having an excellent antitumor effect, stability and metabolic stability. The compound of the present invention...
2018/0265470 Drier Composition and Use Thereof
The invention relates to a drier composition for an autoxidizable alkyd based coating composition, comprising: a) at least one Fe complex comprising Fe and...
2018/0265469 MALEIC ACID SALT OF A SILODOSIN INTERMEDIATE
The present invention relates to a salt of formula (I), the preparation method for preparing same, and the use thereof in the preparation of silodosin. ...
2018/0265468 Born-Based Cycloaddition Catalysts and Methods for the Production of Bio-Based Terephthalic Acid, Isophthalic...
Methods for producing cycloaddition products comprising: reacting a diene with a dienophile in the presence of one or more boron-based catalysts of Formula I...
2018/0265467 PYRAZOLIDINE DERIVATIVES AND RELATED COMPOUNDS
The present invention relates to pyrazolidine derivatives and related compounds, methods of preparing said compounds, pharmaceutical compositions and...
2018/0265466 PYRROLE COMPOUND, COMPOSITIONS AND PROCESS FOR PREPARATION THEREOF
The present invention relates to compositions comprising saroglitazar magnesium wherein the saroglitazar magnesium has a purity of greater than or equal to 99%...
2018/0265465 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF
The invention provides compounds having the general Formula (I); ##STR00001## and pharmaceutically acceptable salts thereof; wherein the variables R.sup.A,...
2018/0265464 Synthetic Sphingolipid-Like Molecules, Drugs, Methods of Their Synthesis and Methods of Treatment
Small molecules comprised of azacyclic constrained sphingolipid-like compounds and methods of their synthesis are provided. Formulations and medicaments are...
2018/0265463 Vitamin D3 Derivatives and Pharmaceutical Use Thereof
The present invention relates to vitamin D.sub.3 derivatives of the following formula, wherein each symbol has the same meaning as defined herein, and...
2018/0265462 NOVEL THIOUREA DERIVATIVES AS ACTIVATORS OF RORalpha AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
Provided is a compound activating ROR.alpha. gene, particularly a JC1 compound containing CGP52608 thiazolidinedione as a lead substance, and a ...
2018/0265461 Method for Producing Carboxylic Acid Thioester
According to the present invention, there is provided a method for producing carboxylic acid thioester, comprising reacting a compound represented by the...
2018/0265460 METHOD OF FORMING PARACYCLOPHANE CONTAINING FUNCTIONAL GROUND WITH DISULFIDE BOND
The present invention provides a method of forming paracyclyophane containing disulfide functional group. The paracyclophane is prepared by adding...
2018/0265459 DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF
Provided are crystalline .alpha., .alpha.-disubstituted amino acids and their crystalline salts containing a terminal alkene on one of their side chains, as...
2018/0265458 PROCESS TO PRODUCE POLYCARBAMATE, POLYCARBAMATE PRODUCED THEREBY AND A COATING COMPOSITION COMPRISING THE...
A process to prepare polycarbamate comprising adding urea to a polyol in the presence of at least one catalyst selected from the group consisting of compounds...
2018/0265457 METHOD FOR PRODUCING ISOCYANATES
The invention relates to a continuously operated method for producing isocyanates by reacting the corresponding amines with phosgene. When changing the target...
2018/0265456 PERSONALIZED, ALLOGENEIC CELL THERAPY OF CANCER
Resins are provided including bisphenol M diphthalonitrile ether resin or bisphenol P diphthalonitrile either resin. Compositions are also provided, including...
2018/0265455 PYRAZOLYL AND PYRIMIDINYL TRICYCLIC ENONES AS ANTIOXIDANT INFLAMMATION MODULATORS
Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: ##STR00001## wherein the variables are defined herein. Also...
2018/0265454 Method for Producing 4-Oxoquinoline Compound
The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production...
2018/0265453 CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS
Disclosed are 2-phenyl-cyclopropylmethanamines which are selective 5-HT(2C) receptor agonists and are used in the treatments of diseases and conditions wherein...
2018/0265452 P62-ZZ CHEMICAL INHIBITOR
A compound, or a pharmaceutically acceptable salt thereof, having a formula I of: ##STR00001## wherein Ar is an arylene or heteroarylene; R.sup.1 has a ...
2018/0265451 AN IMPROVED PROCESS FOR PREPARATION OF TRIENTINE DIHYDROCHLORIDE
The present invention provides a process for preparation of trientine dihydrochloride (1) comprising reaction of protected triethylene tetramine with...
2018/0265450 METHOD OF TREATING OCULAR DISORDERS WITH COMPOUNDS FOUND IN HARDERIAN GLAND SECRETIONS
The present invention is directed to pharmaceutical compositions comprising compounds found in Harderian gland secretions, a method of treating dry eye in a...
2018/0265449 METAL-CATALYZED ALKOXYCARBONYLATION OF A LACTONE
The metal-catalyzed alkoxycarbonylation of a lactone is a method of alkoxycarbonylating a .delta.-lactone, specifically ...
2018/0265448 PROCESS FOR CATALYTIC TRANSVINYLATION OF CARBOXYLIC ACIDS
A carboxylic acid is transvinylated with vinyl ester to give a vinyl ester product and the corresponding acid of the vinyl ester in the presence of a catalyst,...
2018/0265447 PROCESS FOR THE SYNTHESIS OF ACRYLIC ACID OLIGOMERS
A process for the synthesis of acrylic acid oligomer represented by formula (I): ##STR00001## in which n is an integer ranging from 1 to 10, wherein the...
2018/0265446 CATALYST AND METHOD FOR BIODIESEL PRODUCTION FROM UNREFINED LOW-GRADE OIL AND CRUDE AQUEOUS ALCOHOLS
A catalyst for catalyzing transesterification of esters or esterification of fatty acids, the catalyst is selected from the group consisting of manganese (II)...
2018/0265445 P-TOLUIC ACID PRODUCING METHOD
A method for producing highly pure p-toluic acid by a simple solid-liquid separation operation using as a raw material a substance inducible from a biomass...
2018/0265444 SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR PROTEINS AND THEIR USE IN THE TREATMENT OF CANCER
Small molecule stimulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing...
2018/0265443 PROCESS FOR PREPARING 1-[(1R,4R/S,8S)-10,10-DIMETHYL-7-METHYLENE-4-BICYCLO[6.2.0]DECANYL]ETHANO- NE
The present invention relates to a process for preparing 1-[(1R,4R/S,8S)-10,10-dimethyl-7-methylene-4-bicyclo[6.2.0]decanyl]ethano- ne.
2018/0265442 Myricanol Derivatives and Uses Thereof for Treatment of Neurodegenerative Diseases
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular,...
2018/0265441 METHOD OF BISPHENOL MANUFACTURE
An improved method of manufacture of a bisphenol comprises heating a monohydric phenol to a first temperature sufficient to melt the monohydric phenol; adding...
2018/0265440 CARBON DIOXIDE ELECTROLYTIC DEVICE
A carbon dioxide electrolytic device of an embodiment includes: an anode part including an anode which oxidizes water or hydroxide ions to produce oxygen; a...
2018/0265439 POLYFLUOROALKYL ALLYL COMPOUND AND METHOD FOR PRODUCING THE SAME
A polyfluoroalkyl allyl compound represented by the general formula: CF.sub.3(CF.sub.2).sub.n(CH.sub.2CF.sub.2).sub.a(CF.sub.2CF.sub.2).sub.b- ...
2018/0265438 METHODS OF MAKING CHLORINATED HYDROCARBONS
Methods for the manufacture of 1,1,1,2,3-pentachloropropane from 1,1,1,3-tetrachloropropane and chlorine are disclosed. Improved methods are provided for the...
2018/0265437 PROCESS FOR THE PREPARATION OF 2,3,3,3-TETRAFLUOROPROPENE
The invention provides a process for the preparation of 1234yf comprising (a) contacting 1,1,2,3,3,3-hexafluoropropene (1216) with hydrogen in the presence of...
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