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Patent # Description
2018/0264120 NOVEL OPHTHALMIC COMPOSITION COMPRISING REBAMIPIDE AND METHOD FOR PREPARING THE SAME
An ophthalmic composition is provided that includes rebamipide and a method for preparing the same. The ophthalmic composition of maintains its transparency...
2018/0264119 NANOPARTICLES AND METHOD FOR PRODUCING SAME
The nanoparticles of the present invention consist of a molecular aggregate containing an amphipathic block polymer that has a hydrophilic block and a...
2018/0264118 HYDROGEL FORMULATION WITH MILD ADHESION
The present disclosure relates to methods, compositions, and devices for treatments related to mammary tissue in subjects, including reducing the incidence of...
2018/0264117 PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs are provided. The pharmaceutical compositions include a therapeutically...
2018/0264116 Composition, its preparation and method of use in treating skin disorders
This invention pertains to a zafirlukast-containing composition, a method of preparing the composition, and a method for treating certain skin disorders using...
2018/0264115 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These...
2018/0264114 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These...
2018/0264112 Anti-CD40 Antibody Formulations
Provided herein, in some aspects, are low viscosity, low aggregation propensity, high anti-CD40 antibody concentration formulations.
2018/0264111 PHARMACEUTICAL PRODUCT WITH INCREASED STABILITY COMPRISING IMMUNOGLOBULINS
The present invention pertains to a pharmaceutical product comprising a polyclonal immunoglobulin solution in a pre-filled polymer syringe in secondary...
2018/0264110 ANTIBODIES SPECIFIC TO GLYCOSYLATED BTLA (B- AND T- LYMPHOCYTE ATTENUATOR)
Provided herein are molecules, such as antibodies, that selectively bind to glycosylated BTLA (B- and T-lymphocyte attenuator) relative to unglycosylated BTLA....
2018/0264109 MARKERS OF BREAST CANCER AND METHODS FOR THE USE THEREOF
In accordance with the present invention, the single gene SERPINA1 has been identified as a significant predictor of survival in ER+ and ER+/HER2+ breast...
2018/0264108 IMMUNOGLOBULIN-LIKE MOLECULES DIRECTED AGAINST FIBRONECTIN-EDA
The present invention is concerned with immunoglobulin (Ig)-like molecules or fragments thereof for use in treatment, prevention, or prevention of progression...
2018/0264107 TREATMENT OF AUTOIMMUNE DISEASES
The present invention concerns treatment of autoimmune diseases with antagonists which bind to B cell surface markers, such as CD19 or CD20.
2018/0264106 Particles Comprising a Shell with RNA
The present invention relates to RNA decorated particles such as RNA decorated lipid particles, preferably to RNA decorated liposomes. Further, the present...
2018/0264105 NUCLEIC ACID DERIVATIVE HAVING IMMUNOSTIMULATORY ACTIVITY
The purpose of the present invention is to provide double-stranded oligonucleotides comprising the CpG oligonucleotide mentioned below, as a nucleic acid...
2018/0264104 FUCOSYLLACTOSE AS BREAST MILK IDENTICAL NON-DIGESTIBLE OLIGOSACCHARIDE WITH NEW FUNCTIONAL BENEFIT
The invention concerns nutritional compositions with fucosyllactose for use in stimulation of NK cells. The composition is suitable for infants.
2018/0264103 FULLY HUMAN ANTIBODY AGAINST RESPIRATORY SYNCYTICAL VIRUS
Disclosed are an antibody (preferably a fully human antibody R66) against respiratory syncytical virus RSV, encoding nucleic acids thereof, a vetor and a host...
2018/0264102 DUAL ANTHRAX-PLAGUE VACCINES THAT CAN PROTECT AGAINST TWO TIER-1 BIOTERROR PATHOGENS, BACILLUS ANTHRACIS AND...
Bivalent immunogenic compositions against anthrax and plague are disclosed herein. One bivalent immunogenic composition comprises a triple fusion protein...
2018/0264101 FOOT-AND-MOUTH DISEASE VACCINE
Compositions for prevention of Foot and Mouth Disease (FM D) are provided, comprising an antigen component in the amount equivalent to 0.5-20 .mu.g FM D virus...
2018/0264100 Ebola Virus Disease Vaccine Taking Human Replication Deficient Adenovirus As Vector
Provided are an Ebola virus envelope glycoprotein (that is GP protein) codon optimized nucleotide sequence, a human replication deficient recombinant...
2018/0264099 LIVE ATTENUATED ORAL VACCINE AGAINST SHIGELLOSIS AND TYPHOID FEVER
Disclosed is the attenuated Salmonella typhi vaccine Ty21a utilized as a vector for Shigella and/or enterotoxogenic E. coli genes stably integrated in the...
2018/0264098 MODULATION OF REPLICATIVE FITNESS BY DEOPTIMIZATION OF SYNONYMOUS CODONS
Methods of producing a pathogen with reduced replicative fitness are disclosed, as are attenuated pathogens produced using the methods. In particular examples,...
2018/0264097 OMPA AND ASP14 IN VACCINE COMPOSITIONS AND AS DIAGNOSTIC TARGETS
Anaplasma phagocytophilum surface proteins Asp14 and OmpA and homologous genes from Anaplasmatacaea family members are used in compositions suitable for...
2018/0264096 Prophylactic Vaccine to Tumor Angiogenesis
Disclosed are compositions of matter, protocols, and treatment means for inducing an enhanced immunity targeting tumor endothelium in order to prophylactically...
2018/0264095 POPULATION-BASED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM
The disclosure relates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing...
2018/0264094 PERSONALISED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM
The disclosure relates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing...
2018/0264093 IMMUNOGENIC GLYCOPEPTIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Disclosed herein are immunogenic glycopeptide compounds for inducing immune responses to prevent and/or treat cancer. Other aspects of the present disclosure...
2018/0264092 METHODS AND APPARATUS FOR DELIVERING A THERAPEUTIC AGENT TO NASPHARYNGEAL MUCOSA TARGETS
A system for delivering a therapeutic agent to a nasopharyngeal mucosa target comprises a foam generating mechanism, a gas, a therapeutic agent in liquid form...
2018/0264091 ENZYMATIC FRACTIONS WITH ANTI-INFLAMMATORY ACTIVITY
Certain components of crude bromelain extract have surprisingly been found to not support, or to interfere with, the anti-inflammatory benefit of bromelain. By...
2018/0264090 ADENO-ASSOCIATED VIRUS MEDIATED GENE TRANSFER TO THE CENTRAL NERVOUS SYSTEM
A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly...
2018/0264089 MODIFIED IDURONATE 2-SULFATASE AND PRODUCTION THEREOF
Disclosed herein are a modified iduronate 2-sulfatase, a composition comprising a modified iduronate 2-sulfatase, as well as methods for preparing a modified...
2018/0264088 USE OF CREATINE KINASE AND DERIVED PEPTIDES THEREOF TO RELIEVE PAIN
Some embodiments are directed to the use of creatine kinase or fragments thereof which induce analgesia, and also to the use of pharmaceutical compositions...
2018/0264087 TREATMENT OF SHORT BOWEL SYNDROME PATIENTS WITH COLON-IN-CONTINUITY
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
2018/0264086 MAMMALIAN FOLLICLE-STIMULATING HORMONE COMPOSITION WITH INCREASED STABILITY
The present invention pertains to the field of gonadotropins. In particular, an improved composition comprising recombinant human follicle-stimulating hormone...
2018/0264085 Calcitonin Analogues for Treating Diseases and Disorders
Calcitonin analogues as a medicament for producing a decrease in liver triglycerides or for reducing fat accumulation in the liver of a subject are provided.
2018/0264084 METHODS FOR AUTOLOGOUS STEM CELL TRANSPLANTATION
Materials and methods for obtaining populations of lymphocytes and administering the population of lymphocytes to a subject are disclosed herein. In...
2018/0264083 Erythropoietin for Gastrointestinal Dysfunction
This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.
2018/0264082 METHOD OF TREATING ANEMIA USING LONG-ACTING EPO FORMULATION
The present invention relates to a method for treating anemia using a long-acting EPO formulation, and more specifically, a method for treating patients with...
2018/0264081 THERAPEUTIC PROTEIN FORMULATIONS
Systems and methods for preparing a therapeutic protein solution, reducing its viscosity, and administering it to a subject are provided herein. Methods...
2018/0264080 TOPICAL APPLICATIONS OF Kv1.3 CHANNEL BLOCKING PEPTIDES TO TREAT SKIN INFLAMMATION
Disclosed herein are methods for the topical treatment of inflammation of the skin and mucosa by applying a pharmaceutical composition including a protein or...
2018/0264079 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS
The present invention provides a compound, preferably a peptide, having the following characteristics: a) consisting of 9 amino acids in a linear arrangement;...
2018/0264078 NOVEL MICROCIN AND USES THEREOF
Microcin MccPDI and bacteria harboring the mcpM gene which encodes MccPDI limit growth of and/or kill pathogenic bacteria such as pathogenic Escherichia coli...
2018/0264077 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL SUPERINFECTIONS POST-INFLUENZA
The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza. In particular, the...
2018/0264076 COMPOSITION COMPRISING OIL DROPS
A composition comprises a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising an active principle. The invention...
2018/0264075 USE OF A CYCLIC TRIPEPTIDE FOR IMPROVING CELLULAR ENERGY METABOLISM.
The present invention relates to the use of a cyclic peptide comprising the tripeptide reproducing a binding site of fertilin beta to the oocyte integrin, for...
2018/0264074 USE OF POLYMYXIN AS AN ANTIDOTE FOR INTOXICATIONS BY AMATOXINS
The present application refers to the development of a new effective antidote for the poisonous Amanita mushroom species, after exploring an innovative in...
2018/0264073 PHARMACEUTICAL COMPOSITIONS OF WATER SOLUBLE PEPTIDES WITH POOR SOLUBILITY IN ISOTONIC CONDITIONS AND METHODS...
The present invention provides compositions comprising water soluble peptides with poor solubility in isotonic solutions which exhibit enhanced bioavailability...
2018/0264072 POLYPEPTIDES COMPRISING VINCULIN BINDING SITES FOR THE TREATMENT OF PROLIFERATION AND/OR ADHESION RELATED DISEASES
Disclosed are polypeptides including at least one vinculin binding sites, to nucleic acid sequences encoding thereof and to their use for treating a...
2018/0264071 MATERIALS FOR CATHEPSIN B ENHANCEMENT AND METHODS OF USE
The present invention provides methods for treating a subject afflicted with a protein accumulation disease or TBI, comprising administering to the subject at...
2018/0264070 CURCUMA MANGGA VAL ET. ZIPP. EXTRACT AS A TREATMENT TO OVERCOME PROSTATE PROBLEMS
A preparation comprises a herbal extract and/or fraction, and a pharmaceutical preparation includes extract of Curcuma mangga Val. et Zipp., which has...
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