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Patent # Description
2018/0264018 METHODS FOR IMPROVING THE GASTROINTESTINAL TOLERANCE OF FOOD AND BEVERAGE PRODUCTS COMPRISING SWEET,...
The present invention relates to methods for improving the gastrointestinal tolerance of food and beverage products comprising sweet, low-digestible...
2018/0264017 CARBORANE COMPOUNDS AND METHODS OF USE THEREOF
Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ER.beta.) agonists. In some...
2018/0264016 DOSAGE FORMS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE
Osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions.
2018/0264015 LEUKOCYTE INFILTRATION PROMOTING AGENT AND ANTITUMOR IMMUNOSTIMULATORY AGENT
A lysophospholipid receptor-activating substance is able to normalize abnormal blood vessels in tumors without affecting normal blood vessels and to thus...
2018/0264014 COMPOSITIONS AND METHODS FOR TREATING MULTIPLE SCLEROSIS
Provided are compositions and methods for treating multiple sclerosis (MS). One embodiment of the disclosed method entails orally administering to a MS patient...
2018/0264013 COMPOSITION AND METHODS FOR TREATING SLEEP DISORDERS
A method for treating sleep disorders includes the step of administering to a subject in need therefor a pharmaceutical composition comprising one or more...
2018/0264012 COMBINATION OF 25-HYDROXYVITAMIN D AND ANTI-INFLAMMITORIES FOR SUSTAINED PLASMA 17- ESTRADIOL LEVELS
This invention relates to the use of the combination of 25-hydroxyvitamin D3 ("25-OH D3") and antioxidants (ascorbic acid vitamin E and canthaxanthin) to make...
2018/0264011 COMPANION ANIMAL FEED WITH COMBINATION OF 25-HYDROXYVITAMIN D AND ANTIOXIDANTS/ANTI-INFLAMMATORIES
This invention relates to the use of the combination of 25-hydroxyvitamin D3 ("25-OH D3") and antioxidants/anti-inflammatories (ascorbic acid vitamin E and...
2018/0264010 COMBINATION OF 25-HYDROXYVITAMIN D AND ANTIOXIDANTS/ANTI-INFLAMMATORIES FOR BOVINE HEALTH
This invention relates to the use of the combination of 25-hydroxyvitamin D3 ("25-OH D3") and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at...
2018/0264009 METHOD OF PREVENTING OBESITY AND CARDIOVASCULAR PROBLEMS IN POULTRY
Provided is a feed for ameliorating weight gain in poultry comprising 25-hydroxy vitamin D, canthaxanthin, Vitamin E and Vitamin C. Animals fed this...
2018/0264008 COMBINATION
A novel combination comprising a 17 .alpha.-hydroxylase/C17,20 lyase inhibitor, for example: (3.beta.)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol or a...
2018/0264007 PHARMACEUTICAL COMPOSITION
A pharmaceutical composition is described. The composition comprises at least one mometasone compound selected from mometasone, pharmaceutically acceptable...
2018/0264006 COMPOSITIONS COMPRISING TRITERPENOIDS
The invention relates to compositions and formulations comprising at least one triterpenoic acid and at least one neutral triterpenoid and uses thereof for...
2018/0264005 METHODS OF TREATING ERECTILE DYSFUNCTION
An active agent for use in a method of, or for use in the preparation of a medicament for, treating or inhibiting the development of erectile dysfunction...
2018/0264004 NOVEL CHEMOIMMUNOTHERAPY FOR EPITHELIAL CANCER
The invention provides a method for treating cancer in a subject in need thereof, wherein said subject comprises cancer tissue that `contains epithelial cancer...
2018/0264003 INHIBITORS OF THE PLASMODIAL SURFACE ANION CHANNEL AS ANTIMALARIALS
Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a...
2018/0264002 RNA POLYMERASE I INHIBITORS AND USES THEREOF
Provided are novel compounds which are capable of inhibiting an activity of RNA polymerase I, and uses thereof in treating diseases or disorders modulated by...
2018/0264001 SUSTAINED RELEASE OLANZAPINE FORMULATIONS
The disclosure is directed to methods of treating schizophrenia or bipolar disorder by subcutaneously administering a sustained-release dosage form of...
2018/0264000 COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF
The present invention provides modulators of protein function, to restore protein homeostasis, including GSPT1 activity. The invention provides methods of...
2018/0263999 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS
Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds ("diaminophenothiazinium compounds") including...
2018/0263998 PHARMACEUTICAL COMPOSITION OF FUSED AMINODIHYDROTHIAZINE DERIVATIVE
The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): ##STR00001## or...
2018/0263997 PHARMACEUTICAL COMPOSITIONS COMPRISING A JAK INHIBITOR
Pharmaceutical compositions comprising filgotinib maleate Form I and uses thereof are described herein.
2018/0263996 ARYL SULTAM DERIVATIVES AS RORc MODULATORS
Compounds of the formula I: ##STR00001## or a pharmaceutical salt thereof, wherein p, s, A, R.sup.3 and R.sup.e are as defined herein. Also disclosed are methods...
2018/0263995 GENERATION OF MUSCLE LINEAGE CELLS AND THERAPEUTIC USES THEREOF
Methods and compositions for producing mature myotubes are provided herein. In some instances, the method involves contacting a myoblast in an in vitro culture...
2018/0263994 Benzimidazole Derivatives as PI3 Kinase Inhibitors
This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide...
2018/0263993 METHOD FOR PREVENTING AND/OR TREATING CHRONIC TRAUMATIC ENCEPHALOPATHY-IV
The present invention related to a method of preventing and/or treating chronic traumatic encephalopathy.
2018/0263992 TREATMENT OF NEURODEGENERATIVE DISEASES
Methods for the prevention and treatment of neurodegenerative diseases, in particular motor neuron diseases such as amyotrophic lateral sclerosis (ALS), is...
2018/0263991 COMPLEXES AND SALTS OF DIHYDROPYRIMIDINE DERIVATIVES AND THEIR APPLICATION IN PHARMACEUTICALS
This invention relates to L-tartaric acid complexes, acid addition salts, base addition salts of the compound named ...
2018/0263990 CARDIO- AND RENOPROTECTIVE ANTIDIABETIC THERAPY
The present invention relates to a certain DPP-4 inhibitor for use in cardio- and/or renoprotective therapy, including in patients at high vascular risk.
2018/0263989 THERAPEUTIC APPROACHES FOR TREATING PARKINSON'S DISEASE
The present invention relates to compositions and methods for the treatment of Parkinson's disease and related disorders. More specifically, the present...
2018/0263988 SUBSTITUTED PYRAZOLOPYRIMIDINES AS GLUCOCEREBROSIDASE ACTIVATORS
Substituted pyrazolopyrimidines and dihydropyrazolopyrimidines and related compounds, their methods of manufacture, compositions containing these compounds,...
2018/0263987 TREATING MELANOMA WITH MEBENDAZOLE AND A MITOGEN-ACTIVATED KINASE INHIBITOR
Provided herein are methods for treating melanoma in a subject.
2018/0263986 TREATMENT OF ALOPECIA AREATA
The present invention provides a novel treatment of alopecia areate. The problem to be solved by the invention is to provide a new pharmaceutical use of...
2018/0263985 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV
Provided are methods, uses, pharmaceutical regimens, pharmaceutical compositions, and kits comprising modulators of TLR8 and pharmaceutically acceptable salts...
2018/0263984 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS
Compounds of Formula I: ##STR00001## and salts thereof in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, X, Y and n have the meanings given in the specification, are...
2018/0263983 COMBINATION OF CREATINE, AN OMEGA-3 FATTY ACID, AND CITICOLINE
In one aspect, the invention relates to compositions comprising at least one creatine or creatine analog, at least one omega-3 fatty acid, and citicoline...
2018/0263982 CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION
The invention provides methods and compositions that are useful for treating allergic diseases, bacterial infections, fungal infections, viral infections,...
2018/0263981 SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES AND THEIR USE
The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations...
2018/0263980 STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING A PYRIMIDINE-SULFAMIDE
The invention relates to stable pharmaceutical compositions comprising the compound of the below formula, or pharmaceutically acceptable salts, solvates,...
2018/0263979 COMBINATION OF RAF INHIBITORS AND AURORA KINASE INHIBITORS
The present disclosure relates to methods for the treatment of cancers. In particular, the disclosure provides methods for treatment of cancer by administering...
2018/0263978 Bromocriptine Formulations
The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The...
2018/0263977 CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR
Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.
2018/0263976 COMPOSITION AND METHOD FOR TREATMENT OF DEPRESSION AND PSYCHOSIS IN HUMANS
This application relates to combination compositions for use in treatment of depression, and which can alleviate the anxiogenic side effects of certain...
2018/0263975 Methods Of Treating Motor And Movement Disorders And Side Effects Thereof Associated with Parkinson's Disease...
This invention provides methods of treating motor disorder side effects associated with the administration of levodopa to a subject having Parkinson's disease,...
2018/0263974 CRYSTALLINE SALTS OF NALOXONE AND NALTREXONE
This invention relates to crystalline salts of naloxone and of naltrexone and their use as opioid antagonists. The crystalline salts of the invention include...
2018/0263973 COCRYSTALS OF NALOXONE AND NALTREXONE
This invention relates to cocrystals of naloxone and of naltrexone and their use as opioid antagonists. The cocrystals of the invention include naloxone...
2018/0263972 ANALOGS OF DEUTETRABENAZINE, THEIR PREPARATION AND USE
The disclosure is directed to deutetrabenazine analogs, compositions comprising same and methods of detecting same in compositions comprising deutetrabenazine.
2018/0263971 COMBINATION OF TOPOISOMERASE-I INHIBITORS WITH IMMUNOTHERAPY IN THE TREATMENT OF CANCER
The present disclosure relates to compositions and methods for treating cancer, more specifically to methods and compositions comprising a Topoisomerase I...
2018/0263970 COMPOUNDS AND METHODS USEFUL FOR TREATING OR PREVENTING HEMATOLOGICAL CANCERS
The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with DHODH inhibitors, such as ...
2018/0263969 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL INFECTIONS
Pharmaceutical compositions and methods for treating bacterial infections are disclosed.
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