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Patent # Description
2018/0273661 SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE...
The present invention relates to a compound according to Formula (I) wherein R.sup.1 is a hydrocarbyl group selected from the group consisting of alkyl,...
2018/0273660 RADICAL POLYMERISATION OF ETHYLENE INITIATED BY A COUPLE OF ORGANIC PEROXIDES WITH HIGH PRODUCTIVITY
The invention relates to a process for manufacturing polyethylene or an ethylene copolymer, comprising a step of radical polymerization or copolymerization of...
2018/0273659 PROCESS FOR PREPARING POLYMER AND CARBON NANOSPHERES BY CATALYTIC POLYMERIZATION
The present disclosure relates to a process for preparing polymer and carbon nanospheres. In particular, the present disclosure is directed to preparing...
2018/0273658 POLYMER COMPOSITION AND OPTICAL MATERIAL
Provided is a polymer composition, wherein the polymer composition has a refractive index difference (B-A) of 0.04 or greater but 0.1 or less between a minimum...
2018/0273657 RESIN FORMULATION AND USES THEREOF
There is provided a resin formulation comprising a base acrylate monomer or oligomer, a solubilizing acrylate monomer or oligomer, a photoinitiator compound, a...
2018/0273656 CURABLE COMPOSITION AND CURED PRODUCT
To provide a curable composition whereby it is possible to obtain a cured product having a high Abbe number and being excellent in transparency, crack...
2018/0273655 Catalyst Systems and Methods for Preparing and Using the Same
Methods for preparing a catalyst system that includes contacting at least one aromatic hydrocarbon, at least one activator, at least one catalyst having a...
2018/0273654 A PROCESS FOR PREPARING FUNCTIONAL POLYMERS THROUGH ADDITION OF AMINO AND POLYMERYL GROUPS TO ALDEHYDE MOIETIES
The present disclosure relates to a one-pot process for synthesizing functional compounds or functional polymers by reacting an aldehyde with an alkyl-zinc or...
2018/0273653 PROCESS FOR CONVERTING A POLYMERIC ESTER TO A POLYMERIC ACID
The present invention generally relates to processes for converting an ester group to an acid group for polymers having a pendant ester of an acid group. This...
2018/0273652 Iminodiacetic Acid Type Chelate Resin and Method for Producing Same
An iminodiacetic acid type chelate resin which can be easily and efficiently produced and which can efficiently adsorb and separate metal ions; and a method...
2018/0273651 MODIFIED ISOBUTYLENE-ISOPRENE RUBBER, PRODUCTION METHOD FOR SAME AND CURED MATERIAL OF SAME
The present invention provides: a modified isobutylene-isoprene rubber including a structural unit of Chemical Formula I, a production method for the same, and...
2018/0273650 METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER...
Studies have been made for the purpose of achieving both the improvement in the storage stability of a solution-polymerized diene rubber that is modified with...
2018/0273649 CROSSLINKED POLYMER, HYDROGEL OR WATER-BASED FRACTURING FLUID COMPRISING THE SAME, AND METHODS OF MAKING AND...
The invention provides a crosslinked polymer, a hydrogel, a water-based fracturing fluid comprising the same, and methods of making and using thereof. The...
2018/0273648 PROCESS IN WATER FOR THE PREPARATION OF BUTYRIC ESTERS OF HYALURONIC ACID SODIUM SALT
The present invention relates to a process for the preparation of hyaluronic acid butyrate, or a salt thereof, acceptable for pharmaceutical or cosmetic use or...
2018/0273647 METHOD FOR CONCENTRATING BETA-GLUCANS
The presently claimed invention relates to a method for concentrating a beta-glucan comprising at least the following steps: (a1) contacting an aqueous...
2018/0273646 PROCESS FOR PREPARING AN ESTER OF A CELLULOSE ETHER IN THE PRESENCE OF ACETIC ACID AND A REACTION CATALYST
A process for preparing an esterified cellulose ether comprises the step of esterifying a cellulose ether with (i) an aliphatic monocarboxylic acid anhydride...
2018/0273645 METHOD FOR PRODUCING HYDROXYPROPYL METHYL CELLULOSE
Provided is a method for producing hydroxypropyl methyl cellulose (HPMC) having high hydroxypropoxy content, low ash content, and low insoluble fiber content....
2018/0273644 CELLULOSE XANTHATE NANOFIBER
Nanofiber that keep crystallinity are obtained from a cellulose material under light load. The nanofiber are obtained by treating a material containing...
2018/0273643 BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In...
2018/0273642 HETERODIMER BINDING PROTEINS AND USES THEREOF
The present disclosure provides polypeptide heterodimers formed between two different single chain fusion polypeptides via natural heterodimerization of an...
2018/0273641 VL ANTIGEN BINDING PROTEINS EXHIBITING DISTINCT BINDING CHARACTERISTICS
Methods for making, identifying, isolating and/or making binding proteins that contain an immunoglobulin light chain variable domain, including a somatically...
2018/0273640 MODIFIED T LYMPHOCYTES HAVING IMPROVED SPECIFICITY
Provided herein are modified T lymphocytes comprising chimeric receptors and methods of use thereof.
2018/0273639 ANTIBODIES TARGETING QUIESCIN SULFHYDRYL OXIDASE (QSOX1) AND USES OF SAME
An antibody comprising an antigen recognition domain exhibiting species cross reactivity to human QSOX1 and murine QSOX1 is disclosed. Methods of producing the...
2018/0273638 LIN28- MEDIATED CONTROL OF LET-7 BIOGENESIS
The present embodiments provide for compositions and methods that regulate microRNA-binding protein-mediated miRNA biogensis; for example Lin28-mediated...
2018/0273637 METHODS AND COMPOSITIONS FOR TREATMENT OF ATHEROSCLEROSIS
The present invention provides methods and compositions for treating atherosclerosis in a subject comprising the use of therapeutic compounds to reduce Reelin...
2018/0273636 HER2 BINDING PROTEINS BASED ON DI-UBIQUITIN MUTEINS
The present invention relates to new Her2 binding molecules based on di-ubiquitin muteins. The invention further refers to Her2 binding proteins optionally...
2018/0273635 Antigen-Binding Constructs Targeting HER2
Described herein are high affinity antigen binding constructs, e.g., antibodies, directed to the ECD2 domain of HER2. The antigen-binding constructs comprise...
2018/0273634 ANTIBODY POLYPEPTIDES AND USES THEREOF
The present invention provides antibody polypeptides with binding specificity for prostate specific antigen (PSA), wherein the antibody polypeptide comprises...
2018/0273633 ANTIBODIES SPECIFIC FOR CLL-1
Provided herein are antibodies specific for CLL-1.
2018/0273632 ANTI-CD134 (OX40) ANTIBODIES AND USES THEREOF
The invention provides antibodies that specifically bind to human CD134. Invention anti human CD134 antibodies specifically bind to the extracellular domain of...
2018/0273631 HUMAN IMMUNE THERAPIES USING A CD27 AGONIST IN COMBINATION WITH ANOTHER IMMUNE AGONIST TO TREAT CANCER
Methods of inducing T cell proliferation and expansion in vivo for treating conditions wherein antigen-specific T cell immune response are therapeutically...
2018/0273630 ANTI-CD40 ANTIBODIES AND METHODS OF USE
The present invention provides high affinity anti-CD40 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic...
2018/0273629 GLUCAGON RECEPTOR BINDING PROTEINS AND METHODS OF USE THEREOF
The present disclosure provides binding proteins, such as antibodies, that bind glucagon receptors, including a human glucagon receptor, and methods of their use.
2018/0273628 GENERATION OF HUMAN MACROPHAGES IN IMMUNODEFICIENT NON-HUMAN HOSTS
The invention relates to the use of non-anti-human antibodies to stimulate the generation of human macrophages in immunodeficient non-human hosts,...
2018/0273627 ANTI IL-36R ANTIBODIES COMBINATION THERAPY
The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and...
2018/0273626 OMALIZUMAB RESISTANT IGE VARIANTS AND THEIR USE IN ANTI-IGE THERAPY
Omalizumab-resistant IgE variants and methods of using them in combination with omalizumab for treatment of IgE-mediated disorders, including allergic...
2018/0273625 ANTIBODY FOR IMMUNOASSAY AND METHOD FOR PREPARING SAME
Provided are a method of efficiently producing an sIL-2R antigen in an amount necessary for antibody generation, and a method of producing an anti-sIL-2R...
2018/0273624 CANCER IMMUNOTHERAPY BY DISRUPTING PD-1/PD-L1 SIGNALING
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a...
2018/0273623 Bispecific HER2 And CD3 Binding Molecules
Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to...
2018/0273622 CD3 BINDING POLYPEPTIDES
The present disclosure relates to protein molecules that specifically bind to CD3, which may have at least one humanized CD3-binding domain. Such molecules are...
2018/0273621 HUMANIZED ANTI-CD19 ANTIBODIES AND THEIR USE IN TREATMENT OF ONCOLOGY, TRANSPLANTATION AND AUTOIMMUNE DISEASE
The present invention provides chimeric and humanized versions of anti-CD19 mouse monoclonal antibodies. The invention further relates to pharmaceutical...
2018/0273620 ANTIBODY MOLECULES WHICH BIND CD22
The present disclosure relates to antibody molecules comprising a binding domain specific to CD22, said binding domain comprising SEQ ID NO: 1, 2, 3, 4, 5 and...
2018/0273619 DOSAGE REGIMEN FOR MADCAM ANTAGONISTS
The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about...
2018/0273618 Combination Therapy For Treatment Of Disease
The present invention provides methods comprising combination therapy for modulating immune responses, for inhibiting tumor growth, and/or for treating cancer....
2018/0273617 BINDING MOLECULES SPECIFIC FOR ASCT2 AND USES THEREOF
This disclosure provides ASCT2-binding molecules, e.g., anti-ASCT2 antibodies, and antigen-binding fragments thereof. In certain aspects, the ASCT2-binding...
2018/0273616 COMPOSITIONS AND METHODS FOR INHIBITING CANCER STEM CELLS
The disclosure generally provides compositions and methods that are useful in the treatment of cancer. More specifically, the methods and compositions may be...
2018/0273615 METHODS AND COMPOSITIONS COMPRISING PURIFIED RECOMBINANT POLYPEPTIDES
Purified recombinant polypeptides isolated from Chinese hamster ovary host cells, including antibodies, such as therapeutic antibodies, and methods of making...
2018/0273614 ANTAGONISTS OF IL-17C FOR THE TREATMENT AND/OR PREVENTION OF ATOPIC DERMATITIS
The present invention provides antagonists of IL-17C for use in the treatment and/or prevention of atopic dermatitis and related conditions.
2018/0273613 HUMANIZED OR AFFINITY-MATURED ANTI ANG-2 ANTIBODY AND USES THEREOF
An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes...
2018/0273612 METHODS OF PRODUCING ANTI-C5a ANTIBODIES
The present disclosure relates to, inter alia, antibodies, or antigen-binding fragments thereof, that bind to C5a and to use of the antibodies in methods for...
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