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Patent # Description
2018/0271839 COMPOSITIONS AND METHODS FOR TREATING CONDITIONS RELATED TO ELEVATED LEVELS OF EOSINOPHILS AND/OR BASOPHILS
Disclosed herein are methods of treating conditions, which may be associated with elevated levels of eosinophils and/or basophils, with a therapeutically...
2018/0271838 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING PERIPHERAL NEUROPATHY OR SPINAL CORD INJURY
The present invention provides in one embodiment a pharmaceutical composition for treating and/or preventing peripheral neuropathy or spinal cord injury...
2018/0271837 ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF
A compound of Formula (I)) or or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating hearing loss or balance...
2018/0271836 TOPICAL NON-AQUEOUS PHARMACEUTICAL FORMULATIONS CONTAINING AN ALKYL SULFOXIDE FOR THE TREATMENT OF TOPICAL...
The present application relates to non-aqueous pharmaceutical formulations containing an anti-microbial agent.
2018/0271835 INDOMETHACIN ANALOGS FOR THE TREATMENT OF CASTRATE-RESISTANT PROSTATE CANCER
Provided are compositions for inhibiting a biological activity of an aldo-keto reductase family 1, member C3 (AKR1C3) polypeptide. In some embodiments, the...
2018/0271834 PHYTOESTROGEN COMPOSITIONS AND ASSOCIATED METHODS
Methods for controlling estrogen metabolite formation in a subject and compositions for use therein are disclosed and described. In one aspect, estrogen...
2018/0271833 GLYCOPYRROLATE SALTS
Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including...
2018/0271832 REDUCTION OF ER-MAM-LOCALIZED APP-C99 AND METHODS OF TREATING ALZHEIMER'S DISEASE
The invention provides for methods for treating Alzheimer's Disease in a subject by reducing ER-MAM localized APP-C99.
2018/0271831 NEW COMPOSITIONS AND METHODS OF TREATING AND/OR PREVENTING CHRONIC OBSTRUCTIVE PULMONARY DISEASE
The present invention relates to a novel composition or method of use for the treatment and/or the prevention of chronic obstructive pulmonary disease (COPD)...
2018/0271830 COMPOSITION FOR PREVENTING OR TREATING CLIMACTERIC SYMPTOMS COMPRISING SOYBEAN EXTRACT COMPRISING COUMESTROL AS...
The present invention relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin...
2018/0271829 Preparation and Use of a Composition for Prevention and Mitigation of the Effects of Radiation
Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise ...
2018/0271828 MAST CELL STABILIZERS TREATMENT FOR SYSTEMIC DISORDERS
Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders, are provided.
2018/0271827 CANNABINOID COMPOSITIONS AND METHODS OF MAKING
A food additive comprising cannabinoids but lacking at least in part the taste and aroma associated with cannabis while retaining the psychoactive and...
2018/0271826 DRY POWDERS OF CANNABINOIDS AND METHODS FOR PREPARING DRY POWDERS
Dry powders comprise a cannabinoid, a polymer binding agent, a dispersing agent, and a bulking agent, and optionally an antioxidant, and are formed by carbon...
2018/0271825 USE OF SMALL MOLECULE INHIBITORS TARGETING EYA TYROSINE PHOSPHATASE
Inhibitors of EYA tyrosine phosphatase are provided herein, as well as pharmaceutical compositions and methods relating thereto.
2018/0271824 N4-PHENYL-QUINAZOLINE-4-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ERBB TYPE I RECEPTOR TYROSINE KINASE...
This invention provides compounds of Formula I ##STR00001## wherein B, G, A, E, R.sup.1, R.sup.2, R.sup.3, m and n are as defined herein, which are useful as...
2018/0271823 SULFUR-BASED BROAD SPECTRUM ANTIVIRALS
Methods of using the formulations disclosed herein to treat or prevent a broad spectrum of enveloped viruses are provided. In particular, a method of treating...
2018/0271822 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment and prevention of stroke and the sequelae...
2018/0271821 Neuroprotection in Demyelinating Diseases
Methods of treating neurological disorders characterized by extensive demyelination and/or axonal loss are provided. Examples of such disorders include...
2018/0271820 METHODS OF TREATING HEART FAILURE
Pharmaceutical preparations and methods for treating or preventing a heart failure disease, including heart failure with preserved ejection fraction (HFPEF),...
2018/0271819 METHODS OF CANCER TREATMENT
This present disclosure is directed to a method of selecting a cancer for treatment with protein kinase C (PKC) activators, and corresponding methods of...
2018/0271818 OILS WITH ANTI-INFLAMMATORY ACTIVITY CONTAINING NATURAL SPECIALIZED PRORESOLVING MEDIATORS AND THEIR PRECURSORS
The present invention encompasses oils that have anti-inflammatory or resolution-stimulating activity that contain or are enriched with Specialized...
2018/0271817 ALL-NATURAL ENTERIC SOFT CAPSULES
Described herein are soft capsules and enteric soft capsules comprising cationic Type A gelatin and acid insoluble enteric polymers. In particular, the...
2018/0271816 (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and Related Compounds as GABA...
Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
2018/0271815 STORAGE STABLE AQUEOUS INJECTABLE SOLUTION COMPRISING DICLOFENAC
The present invention relates to a stable, aqueous, injectable solution comprising diclofenac and polyvinylpyrrolidone. The present invention also relates to...
2018/0271814 METHOD FOR TREATING CANCER WITH LOW MOLECULAR WEIGHT COMPONENTS OF AURIN TRICARBOXYLIC ACID COMPLEX
A method of preventing and/or treating cancer in a subject is provided. The method includes administering to the subject a composition comprising an effective...
2018/0271813 SPRAYABLE ANALGESIC COMPOSITIONS
A sprayable analgesic composition is an aqueous ethanolic solution which contains a nonsteroidal anti-inflammatory drug (NSAID), lauryl lactate, lactic acid,...
2018/0271812 CALCIUM BASED CLINICAL MATERIAL WITH ANTIMICROBIAL PROPERTIES AND METHOD OF FORMING FOR PREVENTION OR TREATMENT...
Disclosed is an absorbable, calcium based, clinical material with antimicrobial properties and a method of forming for the prevention or treatment of infection...
2018/0271811 Treatment of Alzheimer's Disease using Compounds that Reduce the Activity of Non-Selective CA++ Activated...
NSC antagonists are disclosed as useful in the treatment of dementia, in delaying the onset of dementia, and in the prevention of dementia. Dementia so treated...
2018/0271810 COMPOUNDS FOR USE IN THE TREATMENT OF CONDITIONS ASSOCIATED WITH NADPH OXIDASE
A compound of formula (I) or a pharmaceutically acceptable salt thereof, for use in the treatment of a condition or disorder associated with nicotinamide...
2018/0271809 USE OF NICLOSAMIDE IN THE TREATMENT OF P53-DEFICIENT CELLS
The present disclosure describes a method of treating p53-deficient cells using a niclosamide derivative according to formula (I). The present disclosure...
2018/0271808 METHODS OF REDUCING CHEMORESISTANCE AND TREATING CANCER
Methods of treating cancer include administering a therapeutically effective amount of a pharmaceutical composition containing a pharmaceutically acceptable...
2018/0271807 Meglumine in Combination with Another Therapeutic
The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition...
2018/0271806 NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS
The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and...
2018/0271805 COMPOSITION FOR THE TREATMENT OF HUMAN AND MAMMALIAN ATHEROSCLEROSIS AND PATHOLOGICAL CALCIFICATION IN TISSUE
A compound for treatment of a disorder characterized by at least one of pathological calcification and/or plaque formation including a nutraceutical supplement...
2018/0271804 6-SHOGAOL DERIVATIVES AND ACTIVITIES THEREOF
Derivatives of 6-shogaol are described herein. Also described herein are methods of preparing the derivatives, as well as methods of using the derivatives to...
2018/0271802 METHODS OF DIAGNOSIS AND TREATMENT INVOLVING NITRITE
Methods and therapeutics for treating nitric oxide (NO) mediated condition comprising administering a therapeutically effective amount of a pharmaceutical...
2018/0271801 Zeaxanthin Formulations With Additional Ocular-Active Nutrients, For Protecting Eye Health And Treating Eye...
Oral formulations for promoting eye health, and in particular for preventing or treating macular degeneration, are disclosed, containing zeaxanthin, a...
2018/0271800 MICROCELL SYSTEMS FOR DELIVERING ACTIVE MOLECULES
An active molecule delivery system whereby active molecules can be released on demand and/or a variety of different active molecules can be delivered from the...
2018/0271799 MICROCELL DELIVERY SYSTEMS INCLUDING CHARGED OR MAGNETIC PARTICLES FOR REGULATING RATE OF ADMINISTRATION OF ACTIVES
An active molecule delivery system whereby active molecules can be released on demand and/or a variety of different active molecules can be delivered from the...
2018/0271798 METHODS AND COMPOSITIONS FOR MODIFYING MUCOUS MEMBRANES
The present invention relates to methods and compositions for modifying mucous membranes. In particular, the present invention relates to treating diseases...
2018/0271797 Method and apparatus for the manufacture of fibrous dosage forms
Recently, we have introduced fibrous dosage forms that enable predictable microstructures with a greater range of pharmaceutically relevant properties....
2018/0271796 COMPOSITIONS AND METHODS TO IMPROVE NANOPARTICLE DISTRIBUTION WITHIN THE BRAIN INTERSTITIUM
Improved distribution can be achieved by delivering nanoparticles possessing non-adhesive surfaces via CED in a hyperosmolar infusate solution. This delivery...
2018/0271795 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE
The disclosure relates to polynucleotides comprising an open reading frame of linked nucleosides encoding human methylmalonyl-CoA mutase precursor, human...
2018/0271794 ENCAPSULATED CELLS PRODUCING CYTOCHROME P450 AND METHODS OF USE THEREOF
Disclosed herein are methods and compositions to treat solid tumors. In one embodiment, the method of treating a solid tumor in a patient includes...
2018/0271793 METHOD TO GENERATE MICROCAPSULES WITH HEXAHYDROTRIAZINE (HT)-CONTAINING SHELLS
Materials and methods for preparing a payload-containing microcapsule with walls that have hexahydrotriazine (HT) and/or hemiaminal (HA) structures are...
2018/0271792 ORAL DELIVERY OF PHYSIOLOGICALLY ACTIVE SUBSTANCES
Embodiments may include a composition for oral drug delivery. The composition may include a physiologically active substance, a carrier compound, a...
2018/0271791 SYSTEMS AND METHODS FOR THE FABRICATION OF TABLETS, INCLUDING PHARMACEUTICAL TABLETS
Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of...
2018/0271790 STABLE BENZIMIDAZOLE FORMULATION
A benzimidazole formulation which lacks an intermediate layer and yet which is stable both during storage and during the passage through the stomach, and which...
2018/0271789 SUSTAINED-RELEASE COMPOSITION, METHOD FOR FABRICATING, AND USE THEREOF
The present disclosure provides a sustained-release composition including a sodium hydrosulfide and a carrier. The carrier is provided for carrying the sodium...
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