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Patent # Description
2018/0282296 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER
This invention is in the field of medicinal chemistry. In particular, the invention relates to novel small molecule compounds having a ...
2018/0282295 MATERIALS FOR ORGANIC ELECTTROLUMINESCENT DEVICES
The invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices.
2018/0282294 Process for the Preparation of Velpatasvir
The present disclosure provides a process for the preparation of velpatasvir intermediates. The intermediates may be further converted to velpatasvir or...
2018/0282293 Neuraminidase Inhibitor Compounds, Compositions and Methods for the Use Thereof in Anti-Viral Treatments
Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for...
2018/0282292 Method And System For Production Of A Chemical Commodity Using A Fiber Conduit Reactor
An apparatus includes a conduit with two process fluid inlets at one end of the conduit, one process fluid outlet at an opposing end, a heat exchange medium...
2018/0282291 Identification of Ebsulfur Analogues with Broad-Spectrum Antifungal Activity
The invention relates to novel ebsulfur analogues and novel pharmaceutical compositions comprising ebsulfur analogues. The invention also relates to novel...
2018/0282290 Acylated N-(1,2,5-oxadiazol-3-yl)-, N-(1,3,4-oxadiazol-2-yl)-, N-(tetrazol-5-yl)- and N-(triazol-5-yl)-aryl...
Acylated N-(1,2,5-oxadiazol-3-yl)-, N-(1,3,4-oxadiazol-2-yl)-, N-(tetrazol-5-yl)- and N-(triazol-5-yl)-aryl carboxamides, and use thereof as herbicides ...
2018/0282289 NOVEL AZOLE DERIVATIVES AS APELIN RECEPTOR AGONIST
The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease,...
2018/0282287 AZOLYLACRYLOYL DERIVATIVES AS THERAPEUTIC AGENTS FOR SICKLE CELL DISEASE
Azolylacryloyl derivatives with hypoxic properties are provided. The compounds have a generic formula: and are suitable for treating sickle cell disease and...
2018/0282286 FIPRONIL PRODUCTION PROCESS
An improved oxidation process for preparing 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethy- lsulphinyl-pyrazole, of formula (I) is...
2018/0282285 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS
The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
2018/0282284 PROCESS FOR PREPARATION OF AMINOPYRAZOLE
The present disclosure relates to an improved diazotization process for the preparation of 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole.
2018/0282283 ARYLCYCLOHEXYL PYRAZOLES AS NRF2 REGULATORS
The present invention relates to arylcyclohexyl pyrazole compounds of Formula (I) ##STR00001## methods of making them, pharmaceutical compositions containing...
2018/0282282 ISOQUINOLINES AS INHIBITORS OF HPK1
Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent...
2018/0282281 IMMUNOREGULATORY AGENTS
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such...
2018/0282280 QUINOLINE-BASED PROTEASOME INHIBITORS AND USES THEREOF
Described herein are quinoline compounds useful for, among other things, inhibition of the proteasome and for treatment of cancer and inflammation.
2018/0282279 Pantothenamide Analogues
The present invention concerns novel pantothenamide analogues having antimicrobial activity. In particular, the pantothenamide analogues of the present...
2018/0282278 METHOD FOR SYNTHESIZING BIPYRIDINE COMPOUND AND METHOD FOR MANUFACTURING PYRIDINE COMPOUND
A target bipyridine compound is synthesized with high purity and a high yield in a simple and safe manner in a short period of time. A method for synthesizing...
2018/0282277 METHOD FOR PREPARING A SERIES OF CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC LIGHT-EMITTING DIODES
Disclosed are a method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes. The structure of the material is as...
2018/0282276 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF
The present invention provides the compound represented by Formula 1, and an organic electric element comprising a first electrode, a second electrode, and an...
2018/0282275 New alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides
The present invention relates to novel effective alkynyl-substituted 3-phenylpyrrolidine-2,4-diones according to the general formula (I) or agrochemically...
2018/0282274 FULLERENE DERIVATIVE AND n-TYPE SEMICONDUCTOR MATERIAL
An object of the present invention is to provide a novel fullerene derivative usable in n-type semiconductor materials for organic thin-film solar cells and...
2018/0282273 METHOD FOR OXYGENATIVE COUPLING OF ALKYNES USING ACID CATALYST
The present disclosure relates to a method for preparing various physiologically active pharmaceutical ingredients, such as a 1,1-diaryl compound and a...
2018/0282272 SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS
The invention is concerned with the compounds of formula I or II: ##STR00001## and salts thereof. In addition, the present invention relates to methods of...
2018/0282271 ANTIBIOTIC AMINO ACID MIMETICS
Disclosed are methionine mimetic compounds that possess antibiotic properties in prokaryotic cells. The compounds of this invention comprise a dipeptide having...
2018/0282270 PREPARATION METHOD OF POLYTHIOL FOR OPTICAL LENSES BY USING METAL SULFIDE
Provided is a preparation of a thioether-based polythiol in a high purity using a metal monosulfide for the incorporation of a thioether group, wherein the...
2018/0282269 POLYTHIOL COMPOSITION WITH IMPROVED LONG-TERM STORAGE STABILITY AND OPTICAL LENSES USING SAME
Disclosed is to prevent generation of byproducts or a deterioration in the physical properties of a polythiol composition that may be caused by active oxygen...
2018/0282268 Process for Conversion of Dimethyl Sulfide to Methyl Mercaptan
Disclosed herein are systems and processes involving the catalyzed cleavage reaction of dimethyl sulfide to methyl mercaptan. The catalyzed cleavage reaction...
2018/0282267 METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL
A compound represented by formula (3): ##STR00001## (wherein R.sup.1 represents a C1-C6 alkyl group optionally having one or more halogen atoms, R.sup.2...
2018/0282266 (S)-CSA SALT OF S-KETAMINE, (R)-CSA SALT OF S-KETAMINE AND PROCESSES FOR THE PREPARATION OF S-KETAMINE
The present invention is directed to processes for the preparation of esketamine. The present invention is further directed to processes for the resolution of...
2018/0282265 METHOD FOR THE PROVISION OF CARBON DIOXIDE FOR THE SYNTHESIS OF UREA
The invention relates to a process for separating carbon dioxide from CO.sub.2-containing gases and an apparatus for providing carbon dioxide for the synthesis...
2018/0282264 SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP)
The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically...
2018/0282263 FARNESOID X RECEPTOR AGONISTS AND USES THEREOF
Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising...
2018/0282262 BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE
The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes...
2018/0282261 SYNTHESIS OF TERPHENYL COMPOUNDS
The present invention relates novel methods of synthesizing terphenyl compounds and in particular to novel methods for the synthesis of a compound of Formula I...
2018/0282260 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID POLYMORPHS
The present invention is directed to 1-aminocyclopropane-1-carboxylic acid polymorphs and agricultural compositions thereof.
2018/0282259 COMPOSITION MADE OF AMINO ACID OR ESTER WITH POLYMER QUALITY AND METHODS FOR OBTAINING SAME
The present invention relates to a composition which comprises at least one .alpha.,.omega.-amino-alkanoic acid or ester and at least one alkanoic ester or...
2018/0282258 PROCESS FOR CATALYTIC HYDROGENATION OF HALONITROAROMATICS
The present invention generally relates to processes for the catalytic hydrogenation of halonitroaromatics. In particular, the present invention includes...
2018/0282257 Aromatic Monoester Compositions and Processes for Preparing Same
This disclosure relates to compositions that include one or more aromatic monoesters derived from branched Guerbet alcohols and aromatic acids, or from...
2018/0282256 PROCESS FOR PRODUCING AROMATICS, P-XYLENE AND TEREPHTHALIC ACID, AND DEVICE FOR PRODUCING AROMATICS
The present invention relates to a process for producing aromatics, a process for producing p-xylene and terephthalic acid, and a device for producing...
2018/0282255 Process for the Manufacture of an Adipic Acid Product
Process for the manufacture of an adipic acid product by a reduction of a tetrahydrofuran dicarboxylic acid compound, wherein the tetrahydrofuran dicarboxylic...
2018/0282254 Methods for Preparing Phenolic Branched Chain Alkyl Fatty Acids or Esters Thereof and Methods for Killing...
Disclosed are methods for preparing phenolic branched chain fatty acids or alkyl esters thereof, involving subjecting in a pressurized container (a) at least...
2018/0282253 METHOD FOR PRODUCING ACETIC ACID
There is provided a method allowing industrially efficient production of high quality acetic acid having a good potassium permanganate test value and a low...
2018/0282252 METHOD FOR PRODUCING OPTICALLY ACTIVE 2-(2-FLUOROBIPHENYL-4-YL) PROPANOIC ACID
A novel process for producing optically active 2-(2-fluorobiphenyl-4-yl)propanoic acid is disclosed. This production process is characterized in that a...
2018/0282251 SYSTEMS AND PROCESSES FOR PRODUCING ORGANIC ACIDS DIRECT FROM BETA-LACTONES
Provided herein are reactor systems and processes for producing organic acids directly from beta-lactones. Such reactor systems and processes involve the use...
2018/0282250 VACUUM DISTILLATION FOR ENRICHING CANNABIDIOL
The present invention relates to a method for producing, obtaining and enriching cannabidiol (CBD) and to the use thereof. The invention also relates to a...
2018/0282249 PROCESS FOR THE PREPARATION OF GLYCOLS
A process for the preparation of glycols from a saccharide-containing feedstock comprising the steps of: (a) preparing a reaction mixture in a reactor vessel...
2018/0282248 PROCESS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND TETRAHYDROFURAN FROM FURAN
The present invention provides a process for the preparation of 1,4-butanediol and tetrahydrofuran said process comprising contacting furan with hydrogen and...
2018/0282247 PROCESS FOR THE PREPARATION OF ORGANIC HALIDES
The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their...
2018/0282246 METHOD FOR PRODUCING 1,3-BUTADIENE BY DEHYDROGENATING N-BUTENES, A MATERIAL FLOW CONTAINING BUTANES AND...
The invention relates to a process for preparing 1,3-butadiene from n-butenes, comprising the steps of: A) providing an input gas stream a comprising...
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