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Patent # Description
2018/0297958 ETOMIDATE DERIVATIVE AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF
The present invention discloses an etomidate derivative of Formula 1, or a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, a ...
2018/0297957 COMPOUNDS, POLYMERS AND COATING FORMULATIONS THAT COMPRISE AT LEAST ONE N-HALAMINE PRECURSOR, A CATIONIC CENTER...
The present disclosure relates to a compound that has biocidal activity or is a precursor of a compound with biocidal activity. The compound comprises an...
2018/0297956 CRYSTAL FORM OF QUINOLINE COMPOUND AND PROCESS FOR ITS PRODUCTION
A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin...
2018/0297955 N-(4-HYDROXY-4-METHYL-CYCLOHEXYL)-4-PHENYL-BENZENESULFONAMIDE AND ...
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted...
2018/0297954 2,4-DIHYDROXY-NICOTINAMIDES AS APJ AGONISTS
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, O and compositions comprising any of such...
2018/0297953 PYRIDINE COMPOUND
A pyridine compound represented by formula (I), or an N-oxide thereof is provided, wherein the variable groups are as defined in the specification. The...
2018/0297952 CATALYTIC HYDROGENATION OF SUBSTITUTED CYANOPYRIDINES AND PROCESS FOR PREPARING SUBSTITUTED PYRIDYLMETHYLBENZAMIDES
The present invention relates to novel processes for the preparation of substituted pyridyl-methylbenzamide derivatives of formula (I), in particular ...
2018/0297951 PROCESS FOR THE PREPARATION OF FEXOFENADINE AND OF INTERMEDIATES USED THEREIN
A new process for the preparation of fexofenadine and of related intermediates, which can be used in the preparation of fexofenadine, is provided.
2018/0297950 ORGANIC ELECTROLUMINESCENT MATERIAL
The present invention discloses an organic electronic luminescent material, with the chemical formula (I). The compounds having the chemical formula (I) in the...
2018/0297949 METHODS OF PREPARING TECOVIRIMAT
Disclosed are methods for the preparation of Tecovirimat for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly...
2018/0297948 SODIUM CHANNEL BLOCKERS
The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and use...
2018/0297947 TRITIATED NITROXIDES AND USES THEREOF
Long-term and high-density energy sources are described that utilize radioisotope batteries that provide a tritium (.sup.3H)-based direct energy conversion...
2018/0297946 POLYMORPHIC FORM OF PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF
The present invention relates to Saroglitazar free acid of Formula (IA) or its pharmaceutically acceptable salts, pharmaceutically acceptable solvates,...
2018/0297945 POLYMORPHIC FORM OF PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF
The present invention relates to Saroglitazar free acid of Formula (IA) or its pharmaceutically acceptable salts, pharmaceutically acceptable solvates,...
2018/0297944 SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS
The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases. ##STR00001##
2018/0297943 METHOD FOR PRODUCING POLYTHIOL COMPOUND, METHOD FOR PRODUCING CURABLE COMPOSITION, AND METHOD FOR PRODUCING...
Provided is a method for producing a polythiol compound, including obtaining one or more polythiol compounds selected from the group consisting of a polythiol...
2018/0297942 POLYAMINE SULFONAMIDES AND USES THEREOF
Cancer is a disease for which there remains a great unmet medical need, and therefore the discovery and development of new antineoplastic agents is critically...
2018/0297941 PROCESS FOR PREPARATION OF N-BOC BIPHENYL ALANINOL
A process is provided for preparation of (R)--N-Boc biphenyl alaninol. It provides a preparation process for a compound outlined as compound 4, which includes...
2018/0297940 METHOD FOR CONTROLLING THE PROCESS FOR MAKING ISOCYANATES
The invention relates to a method for preparing an aromatic polyisocyanate in an isocyanate plant comprising a reaction section for a phosgenation reaction,...
2018/0297939 ALPHA-CINNAMIDE COMPOUNDS AND COMPOSITIONS AS HDAC8 INHIBITORS
The present invention relates to inhibitors of histone deacetylases, in particular HDAC8, that are useful for the treatment of cancer and other diseases and...
2018/0297938 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY
Here described are compounds consisting of the structure (targeting molecule).sub.m-linker-(targeting molecule).sub.n, wherein the targeting molecule is a retinoid or...
2018/0297937 NOVEL VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX
This invention relates to a wax composition comprising a plurality of fatty acid amide compounds having the Formula (I): ##STR00001## where R.sup.1, R.sup.2,...
2018/0297936 Diabetes and Metabolic Syndrome Treatment with a Novel Dual Modulator of Soluble Epoxide Hydrolase and...
A catheter assembly includes an elongated catheter shaft, a magnetic sensor, and one or more wires. The elongated catheter shaft has a shaft proximal end and a...
2018/0297935 BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS AND USES THEREOF
.beta.-Substituted .beta.-amino acids, .beta.-substituted .beta.-amino acid derivatives, and .beta.-substituted .beta.-amino acid analogs and (bio)isosteres...
2018/0297934 TETRAHYDRO-ISOHUMULONE DERIVATIVES, METHODS OF MAKING AND USING
The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical...
2018/0297933 PROCESS FOR PREPARING A DIAMINE/DICARBOXYLIC ACID SALT
Processes are disclosed for preparing a diamine/dicarboxylic acid salt, wherein the dicarboxylic acid includes an aromatic dicarboxylic acid and is provided in...
2018/0297932 NICKEL DIATOMACEOUS EARTH CATALYST AND METHOD FOR PRODUCING THE SAME
A nickel diatomaceous earth catalyst having a weight loss rate measured by hydrogen-TG at 400 to 600.degree. C. of 0.05 to 2.0%.
2018/0297931 Compositions and Methods for the Treatment of Fatty Acid Metabolism Disorders
Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject...
2018/0297930 PROCESS FOR PURIFICATION OF METHYL METHACRYLATE
A process for purifying methyl methacrylate. The method comprises: (a) feeding a product mixture comprising methyl methacrylate, methanol, water and oligomers...
2018/0297929 GEMCABENE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR
This present invention provides gemcabene pharmaceutically acceptable salts having a PSD90 of 35 .mu.m to about 90 .mu.m, methods for purifying crude...
2018/0297928 COMPOSITIONS AND METHODS FOR AMELIORATING CNS INFLAMMATION, PSYCHOSIS, DELIRIUM, PTSD OR PTSS
The invention provides compositions and methods for ameliorating, treating, reversing or preventing pathology or inflammation in the central nervous system...
2018/0297927 PROCESS FOR THE PURIFICATION OF LEVULINIC ACID
A process for the purification of levulinic acid including the following steps: a. providing a composition 1, comprising at least 75 wt. % of levulinic acid;...
2018/0297926 HYDROFORMYLATION PROCESS FOR PRODUCING 1,6-DISUBSTITUTED HEXANE DERIVATIVES
The invention relates to a process for the production of 1,6-difunctionalized hexane derivatives from 1,3-diunsaturated hydrocarbons, preferably butadiene,...
2018/0297925 METHODS FOR TOTAL SYNTHESIS OF RESOLVIN E1
Methods for total chemical synthesis of Resolvin E1 (RvE1) include Wittig reaction of two compounds having hydroxyl protecting group in the presence of a...
2018/0297924 HYDROXYLATED TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES IN HERPESVIRUS AND HEPATITIS B AND USES THEREFOR
The present disclosure relates to inhibitors of herpesvirus nucleic acid metabolism and inhibitors of Hepatitis B virus. Also provided are methods of treatment...
2018/0297923 ERR MODULATORS AND USES THEREOF
Disclosed herein, inter alia, are compositions and methods useful for treating non-alcoholic fatty liver diseases.
2018/0297922 NOVEL OCTAHYDROINDENYL PROPANAL COMPOUNDS
The present invention pertains to novel octahydro-indene compounds and their unexpected advantageous use thereof in enhancing, improving or modifying the...
2018/0297921 Method of Production of Methanol Using CO2 and H2
Utilizing the common knowledge formula for creation of methanol CO.sub.2+3H.sub.2.fwdarw.CH.sub.3OH+H.sub.2O; for each mole of carbon dioxide, three moles of...
2018/0297920 PROCESS FOR THE PRODUCTION OF GLYCOLS
A process for the production of glycols is provided, the process comprising contacting a saccharide-containing feedstock with hydrogen in the presence of a...
2018/0297919 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE
A process for producing a main (hydro)halocarbon compound, including the formation of a mixture of compounds including hydrogen fluoride, ...
2018/0297918 MANUFACTURING METHOD OF 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE
There is provided an economically advantageous manufacturing method capable of efficiently obtaining 1-chloro-2,3,3,3-tetrafluoropropene by using...
2018/0297917 DEHYDROHALOGENATION REACTOR AND PROCESS
The invention provides a reactor comprising a reaction chamber having a catalytic surface in contact with reactants in said chamber, and a source for passing...
2018/0297916 POLYMERIZATION INHIBITING SYSTEM AND POLYMERIZATION INHIBITING METHOD
A polymerization inhibiting system includes a measuring apparatus, a supplying apparatus and a control apparatus. The measuring apparatus is configured to...
2018/0297915 METHOD FOR PREPARING ETHYLENE WITH IMPROVED ENERGY EFFICIENCY
Provided is a method for preparing ethylene with improved energy efficiency which can reduce energy due to direct heat exchange between processes.
2018/0297914 METHOD OF OXIDATIVE DEHYDROGENATION OF HYDROCARBON COMPOUNDS
A method of oxidative dehydrogenating a butane-containing hydrocarbon stream by contacting the same with a bimetallic catalyst in the presence of an oxidant,...
2018/0297912 PROCESS FOR THE OXIDATIVE COUPLING OF METHANE
A process for the oxidative coupling of methane to one or more C2+ hydrocarbons which includes subjecting a gas stream comprising methane, ethylene, optionally...
2018/0297911 MATERIALS AND METHODS FOR PRODUCING ALKENES AND DERIVATIVES THEREOF
The present disclosure relates to processes for production of alkene products from their alkene precursors, such as 3-hydroxyacid and alcohols, via either (1)...
2018/0297910 PROCESS FOR PRODUCING STYRENE
The invention relates to a process for the preparation of styrene or substituted styrenes comprising the steps of: (a) subjecting a feed containing 1-phenyl...
2018/0297909 METHOD OF MANUFACTURING PRESS POLYMER-BONDED EXPLOSIVE USING POLYMER EMULSION AND PRESS POLYMER-BONDED...
A method of manufacturing a press polymer-bonded explosive, in which a polymer emulsion is used to maximize the efficiency of a process, and a press...
2018/0297908 A GRANULAR FERTILIZER OR SOIL CONDITIONER AND A USE THEREOF
A granular fertilizer or soil conditioner (10) containing a bio-based core matrix (12) with at least one nitrogen compound and an inert barrier layer (12)...
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