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Patent # Description
2018/0311390 DEVICE FOR REDUCING ODOR IN ATHLETIC APPAREL STORAGE
A device which reduces odor in athletic apparel storage, notably athletic or "gym" bags, lockers, and similar places where athletic apparel might be stored...
2018/0311389 AERATION METHOD OF ISOLATOR SYSTEM
In a state where an incubator 3 is connected to an isolator 2 through a chamber 4 and opening/closing doors 11B and 12 are closed, a decontaminating gas G is...
2018/0311388 PORTABLE LIGHT FASTENING ASSEMBLY
A portable light fastening assembly for use with the human interface of an electronic device includes a lamp housing and an adjustable attachment device...
2018/0311387 SINGLE-EMITTER LIGHTING DEVICE THAT OUTPUTS A MINIMUM AMOUNT OF POWER TO PRODUCE INTEGRATED RADIANCE VALUES...
A lighting device configured to deactivate dangerous microorganisms in an environment. The lighting device includes at least one lighting element with a single...
2018/0311386 Lighting Device that Deactivates Dangerous Pathogens While Providing Visually Appealing Light
A lighting system configured to provide light and disinfect air in an environment. The lighting system includes an HVAC unit configured to provide air to the...
2018/0311385 NOVEL KININ-BASED THERANOSTIC PROBES FOR SOLID CANCERS AND USES THEREOF
It is provided new chemical entities allowing simultaneous diagnosis and treatment of cancers. More specifically, it is provided a theranostic compound...
2018/0311384 METHOD
The present invention relates to new and improved methods of synthesizing radiolabelling agents which can be used to label biomolecules for use as ...
2018/0311383 USING A BLUE-SHIFTED REFERENCE DYE IN AN OPTICAL GLUCOSE ASSAY
The invention is directed to a competitive glucose binding affinity assay comprising a glucose receptor (typically mannan binding lectin) labeled with an assay...
2018/0311382 MODIFIED-DEXTRANS FOR USE IN OPTICAL GLUCOSE ASSAYS
The invention is directed to a competitive glucose binding affinity assay comprising a glucose receptor (typically mannan binding lectin) labeled with an assay...
2018/0311381 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA...
2018/0311380 PROSTATE-TARGETING ADENO-ASSOCIATED VIRUS SEROTYPE VECTORS
The disclosure relates to compositions and methods for rAAV-mediated delivery of a transgene to a subject. In some embodiments, the rAAV transduces the...
2018/0311379 COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
The present invention relates to a complexed RNA, comprising at least one RNA complexed with one or more oligopeptides, wherein the oligopeptide has a length...
2018/0311378 SYNTHETIC PLATELETS
Provided herein are various functionalized particles comprising a shell, dendritic linkers, and functional moieties. The dendrimer linkers allow very large...
2018/0311377 DRUG DELIVERY SYSTEMS USING FC FRAGMENTS
The present invention provides drug delivery systems comprising FcRn binding partners (e.g., FcRn binding partner, Fc fragment) associated with a particle or...
2018/0311376 A Medical Composition and a Medical Hydrogel for Use in the Prevention and/or Treatment of a Disease of the...
The invention relates to medical compositions, a medical hydrogel, a medical kit and a multichamber discharge device for use in the prevention and/or treatment...
2018/0311375 PROCESS OF PREPARING ANTIBODY-DRUG CONJUGATE
The invention provides process for preparing antibody-drug conjugates, preferably trastuzumab maytansinoid conjugate linked via non-cleavable linker comprising...
2018/0311374 TARGETED CANCER THERAPY
Some embodiments of the present disclosure are directed to methods that include delivering to a subject a papillomavirus particle or soluble papillomavirus...
2018/0311373 CONJUGATE MOLECULE
This invention relates to a therapeutic molecule capable of suppressing an immune response against an organ or tissue transplantation in a patient. In...
2018/0311372 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING GLP-1 RECEPTOR AGONISTS CONJUGATED TO ANTAGONISTS...
Methods of treating metabolic diseases and disorders using a composition comprising an antigen binding protein specific for the GIPR polypeptide conjugated to...
2018/0311371 ANTI-TPBG ANTIBODIES AND METHODS OF USE
The invention provides anti-TPBG antibodies and methods of using the same.
2018/0311370 METHOD FOR PREVENTION OR TREATMENT OF ONE OR MORE OF DISEASES RELEVANT TO THE PROTEIN IN THE PROTEIN-CELL...
The present invention pertains to immunology, biomedicine field, specifically relates to a method for prevention or treatment of one or more of diseases...
2018/0311369 PEPTIDE-BASED MOLECULES FOR MODULATING CAR EXPRESSION OR ACCESSIBILITY AND USES THEREOF
Peptide-based molecules for modulating expression or accessibility to the coxsackievirus and adenovirus receptor (CAR) are disclosed. Cell-permeable...
2018/0311368 Modified Relaxin Polypeptides and Their Uses
Modified relaxin polypeptides and their uses thereof are provided
2018/0311367 MULTIVALENT PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME
Novel peptoid oligomers are disclosed that have a formula represented by the following formula Ia or Ib: ##STR00001## The peptoid oligomers are prepared as...
2018/0311366 Immunostimulating-Toxic RNA In Alkaline Earth Metal Formulation
A composition including an immunostimulating RNA molecule in a dication containing solution wherein the RNA includes a chemical modification which is toxic to...
2018/0311365 Modulators of PCSK9 Expression
The present embodiments provide methods, compounds, and compositions useful for inhibiting PCSK9 expression, which may be useful for treating, preventing, or...
2018/0311364 Protease Triggered Release Of Molecules From Hydrogels
The invention concerns compositions comprising: (i) biocompatible hydrogel, comprising a plurality of cross-linkers connecting backbone components of the...
2018/0311363 TRANSDERMAL ABSORPTION PREPARATION PRECURSOR
A transdermal absorption preparation precursor 50 containing a release liner 10 containing one first valley fold part 1, one or two first mountain fold parts...
2018/0311362 TRANSDERMAL ABSORPTION PREPARATION
Provided is a transdermal absorption preparation that shows superior skin permeability of a drug and that does not easily cause cold flow. A transdermal absorption...
2018/0311361 Compositions
The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and...
2018/0311360 Sprayable Topical Carrier and Composition Comprising Phosphatidylcholine
A pharmaceutical or cosmetic carrier for topical administration substantially consists of phosphatidylcholine, monoglyceride, fatty acid ester of...
2018/0311359 Antibody Formulations and Uses Thereof
The present application relates to formulations of anti-CD105 antibodies, antigen-binding fragments thereof, and uses thereof. Another aspect relates to...
2018/0311358 THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS
A thermoformable dual network hydrogel composition formed from a cross-linked polymer derived from one or more olefinically unsaturated polymerizable...
2018/0311357 EXTERNAL PREPARATION AND METHOD FOR PRODUCING SAME
An object of the present invention is to prevent a particle including a first fraction containing an active ingredient and a second fraction containing a...
2018/0311356 METHOD TO INHIBIT ENDOTHELIAL-TO-MESENCHYMAL TRANSITION
Embodiments herein provide for compositions and methods for inhibiting pathological endothelial-to-mesenchymal transition (EndMT), e.g., in endothelial cells...
2018/0311355 METHODS FOR RADIOTHERAPY TO TRIGGER LIGHT ACTIVATION DRUGS
A method and system for treating a subject with a disorder which provides within the subject at least one photoactivatable drug for treatment of the subject,...
2018/0311354 IMMUNOMAGNETIC NANOCAPSULE, PHARMACEUTICAL COMPOSITION THEREOF FOR TREATING CANCER AND KIT FOR TREATING CANCER
An immunomagnetic nanocapsule includes a core, a shell and an outer layer. The shell is formed by a complex, and the complex is fabricated by a combination of...
2018/0311353 TRIPLET-TRIPLET ANNIHILATION-BASED UPCONVERSION
The present invention generally relates to various photoreactions, including reactions generally based on triplet-triplet annihilation upconversion. One aspect...
2018/0311351 STABLE AQUEOUS FORMULATIONS OF ADALIMUMAB
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
2018/0311350 STABLE AQUEOUS FORMULATIONS OF ADALIMUMAB
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
2018/0311349 STABLE AQUEOUS FORMULATIONS OF ADALIMUMAB
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
2018/0311348 TRISPECIFIC MOLECULE COMBINING SPECIFIC TUMOR TARGETING AND LOCAL IMMUNE CHECKPOINT INHIBITION
The present invention relates to a novel molecule comprising three binding sites with specificity for a tumor cell, for an effector cell and for a checkpoint...
2018/0311347 POLYMORPHISMS IN CACHEXIA PREDICT CLINICAL OUTCOMES OF COLORECTAL CANCER PATIENTS RECEIVING IRINOTECAN AND...
Methods are provided for treating colorectal cancer patients with a therapy comprising irinotecan and bevacizumab. The methods entail administering the therapy...
2018/0311346 COMBINATION THERAPY OF IMMUNOTOXIN AND CHECKPOINT INHIBITOR
Regional, tumor-targeted, cytotoxic therapy, such as D2C7-immunotoxin (D2C7-IT), not only specifically target and destroy tumor cells, but in the process...
2018/0311345 A METHOD OF INHIBITING EXACERBATIONS OF T CELL-MEDIATED ALLOGRAFT VASCULOPATHY
The disclosure provides a method of reducing the likelihood of forming a T cell-mediated allograft vasculopathy lesion in a mammalian transplant recipient...
2018/0311344 MATERIALS AND METHODS FOR MODULATING IMMUNE RESPONSES
The present invention provides materials and methods for modulating an immune response. In one embodiment, the present invention provides an initial artificial...
2018/0311343 MESSENGER RIBONUCLEIC ACIDS FOR ENHANCING IMMUNE RESPONSES AND METHODS OF USE THEREOF
The disclosure features isolated mRNAs encoding a polypeptide that enhances immune responses to an antigen(s) of interest, such as polypeptides that activate...
2018/0311342 IMMUNOSTIMULATING AGENT
The present invention aims to provide an immunostimulating agent superior in an immunostimulatory effect, particularly a compound useful as a vaccine adjuvant,...
2018/0311341 METHOD FOR ENHANCING GENERATION OF ANTIGEN-SPECIFIC CYTOTOXIC T LYMPHOCYTES (CTL) AND ANTIBODIES
Provided are a composition and a food or drink, having the effect of enhancing an immune response to an antigen, which is administered by another route such as...
2018/0311340 NEW ADJUVANT AND VACCINE COMPOSITION CONTAINING THE SAME
The present invention relates to certain polyphenol(s) having adjuvant property that can be used for the vaccine preparation. Also, the current invention...
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