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Patent # Description
2018/0311289 INFECTION PROTECTIVE AGENT FOR INFANTS
Provided herein is an infection protective agent for ameliorating infections in infants, particularly newborns, without causing side effects. The infection...
2018/0311288 BIOEFFECTIVE KRILL OIL COMPOSITIONS
This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The...
2018/0311287 Modulation of Splenocytes in Cell Therapy for Traumatic Brain Injury
The invention provides methods for treating traumatic brain injury. The invention is generally directed to treating traumatic brain injury by administering...
2018/0311286 Method of Committed Differentiation of Human Induced Pluripotent Stem Cells into Leydig Cells and Application...
The present application provides an in-vitro committed differentiation method for inducing human induced pluripotent stem cells (hiPSCs) into Leydig cells...
2018/0311285 METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN USING HUMAN BIRTH TISSUE MATERIAL COMPOSITION
Methods of treating inflammation, pain or both inflammation and pain in a subject are provided. The method includes the step of administering a human birth...
2018/0311284 AMNIOTIC FLUID TOPICAL FORMULATION
A human amniotic fluid formulation has been developed for topical application to the eye, which is useful for the treatment of ocular diseases and injuries...
2018/0311283 PRODUCTS DERIVED FROM AMNIOTIC FLUID AND METHODS OF USE
Uncultured amniotic cell and protein fraction products derived from amniotic fluid and methods of preparing and using those compositions are provided....
2018/0311282 CHAMBER FOR ENCAPSULATING SECRETING CELLS
The invention relates to an encapsulating chamber for secreting cells, comprising a closed shell made of a semi-permeable membrane, said membrane comprising at...
2018/0311281 PRIMED MUSCLE PROGENITOR CELLS AND USES THEREOF
This invention relates to a method for repairing and reconstructing a damaged or non-functional muscle, in particular to a method and a tool kit using in vitro...
2018/0311280 Dosing Regimen for Treatment of Cognitive and Motor Impairments with Blood Plasma and Blood Plasma Products
Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and...
2018/0311279 HERBO-MINERAL FORMULATION FOR PREVENTION, TREATMENT AND MANAGEMENT OF RENAL DISORDERS AND METHOD OF PREPARATION...
Herbo-mineral formulation for prevention and treatment of Renal disorders are disclosed herein. The formulation includes combination of herb and mineral...
2018/0311278 PHARMACEUTICAL PREPARATION FOR DELIVERY OF POROUS MATERIAL TO LARGE INTESTINE OR LOWER PART OF SMALL INTESTINE
The problem with which the present invention is concerned is providing a novel pharmaceutical preparation, the restrictions on the administration of which to a...
2018/0311276 Method and Apparatus for Treating Oral Disease in Animals
Embodiments of the present invention are directed to methods and apparatus for the treatment of plaque, halitosis and other oral diseases in animals such as...
2018/0311275 Method, Target and Application for NO Accumulation to Decrease Pseudomonas Aeruginosa Invasiveness
Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa (P. aeruginosa); achieving NO accumulation...
2018/0311274 IN SITU NEUTRALIZATION COMPOSITION
A topical composition for treatment of conditions marked by elevated skin pH may include a partially neutralized carbomer vehicle neutralized to a pH less than...
2018/0311273 Method of Treating Inflammation
The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising...
2018/0311272 Compositions and Methods for Treating Joints
Compositions and methods are provided for treating joint conditions, such as osteoarthritis and/or the pain associated therewith. The compositions and methods...
2018/0311271 USE OF BETA-1,3-GLUCAN FOR MODULATING IMMUNE FUNCTION AND TREATING INTESTINAL INFLAMMATION
The present application relates to beta-1,3-glucan and uses thereof to modulate immunity in the human body. Also provided are methods for treatment and/or...
2018/0311270 RNA MOLECULE FOR REPAIRING DNA DAMAGE
The purpose of the present invention is to obtain a novel and effective composition for ameliorating DNA damage. Used is a composition for ameliorating DNA...
2018/0311269 TARGETED CANCER THERAPY
Some embodiments of the present disclosure are directed to methods that include delivering to a subject a nucleic acid encoding an antigen, wherein the nucleic...
2018/0311268 RESPONSE-GUIDED HCV THERAPY
The present disclosure relates to solid dosage forms comprising anti-HCV compounds and methods of using such dosage forms to treat or prevent HCV infection....
2018/0311267 METHODS FOR TREATING PULMONARY NON-TUBERCULOUS MYCOBACTERIAL INFECTIONS
Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection...
2018/0311266 COMPOSITIONS COMPRISING AND METHODS OF USING INHIBITORS OF SODIUM-GLUCOSE COTRANSPORTERS 1 AND 2
Pharmaceutical dosage forms useful for improving the cardiovascular and/or metabolic health of patients, particularly those suffering from type 2 diabetes, are...
2018/0311265 Methods and Compositions for Treatment of COPD Diseases
The present disclosure relates to treatment of a pulmonary disease. The methods and kits provided herein facilitate relieving the symptoms resulting from the...
2018/0311264 COMPOSITION FOR MODULATING IRAK1
The present invention relates to the treatment of breast cancer, more particularly triple negative breast cancer (TNBC), with the use of an inhibitor of...
2018/0311263 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS
Provided are compounds, methods, and pharmaceutical compositions for treating Filoviridae virus infections by administering ribosides, riboside phosphates and...
2018/0311262 19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF
Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I): ##STR00001## and pharmaceutically acceptable salts thereof; wherein ,...
2018/0311261 METHODS OF TREATING ADVANCED PROSTATE CANCER
Provided herein are methods for treating metastatic prostate cancer using anti-androgen compounds and radionuclide-labeled androgens.
2018/0311260 CORTICOSTEROIDS FOR THE TREATMENT OF JOINT PAIN
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or...
2018/0311259 OXYSTEROLS AND HEDGEHOG SIGNALING
Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit Hedgehog signaling. Also described herein are methods...
2018/0311258 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
Described herein are deuterium-enriched neuroactive steroids of the Formula (II) or a pharmaceutically acceptable salt thereof; wherein R.sup.2a, R.sup.2b,...
2018/0311257 SELECTIVE HDAC8 INHIBITORS AND THEIR USES
The present invention relates to small molecule compounds based on benzopyrimido- or benzoimidazo-thiazin-imine as well as their (synthesis) intermediates and...
2018/0311256 METHOD OF TREATING PATIENTS COADMINISTERED A FACTOR Xa INHIBITOR AND VERAPAMIL
The present disclosure in various embodiments teaches methods of treating patients in need of treatment with a Factor Xa inhibitor, and who are also...
2018/0311255 FUSED IMIDAZO-PIPERIDINE JAK INHIBITOR COMPOUND
The invention provides a compound of formula 1 ##STR00001## or a pharmaceutically-acceptable salt thereof, that is useful as a JAK inhibitor. The invention also...
2018/0311254 DNA-PK INHIBITORS
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said...
2018/0311253 USE OF PAR-1 ANTAGONISTS FOR PREVENTING AND/OR TREATING PELVI-PERINEAL FUNCTIONAL PATHOLOGICAL CONDITIONS
The present invention relates to the use of PAR1 antagonists, in particular of vorapaxar, of atopaxar and of ...
2018/0311252 Therapeutic Targeting of Casein Kinase 1 Delta in Breast Cancer
The invention provides a method of inhibiting casein kinase 1.delta. (CK1.delta.), comprising contacting the CK1.delta. with a compound of formula (I), as...
2018/0311251 EZH2 INHIBITORS FOR TREATING LYMPHOMA
The present disclosure relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents,...
2018/0311250 MACROCYCLIC SPIROCARBAMATE DERIVATIVES AS FACTOR XIA INHIBITORS, PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS AND...
The present invention provides a compound of Formula (I) and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds and said...
2018/0311249 COMBINATION THERAPY FOR TREATING MALIGNANCIES
Provided are methods and compositions for treating AML in patients carrying an IDH2 mutation using a combination of an inhibitor of a mutant IDH2 enzyme and an...
2018/0311248 COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES
Compounds and compositions for treating injuries caused by exposure to chemical warfare agents are described herein.
2018/0311247 COMBINATION THERAPIES FOR TREATING CANCERS
Provided herein are methods that relate to a therapeutic strategy for treatment of cancer, and allergic, autoimmune, and inflammatory disorders including...
2018/0311246 KINETIN/ZEATIN TOPICAL FORMULATION
The solubility of kinetin and/or of zeatin is increased when either or both are combined in a formulation that includes a polyoxyalkylene-n-glycerol...
2018/0311245 USE OF A COMBINATIONAL THERAPY OF LSD1 INHIBITORS WITH CDK2 INHIBITORS IN THE TREATMENT OF CANCER
The present disclosure relates to methods of treating cancer and pharmaceutical compositions for use in the treatment of cancer, including ...
2018/0311244 METHODS OF TREATING LIVER DISEASE
The present disclosure relates to a method of preventing and/or treating liver disease comprising administering an ASK1 inhibitor in combination with a ACC...
2018/0311243 NURR1:RXR ACTIVATING COMPOUNDS FOR SIMULTANEOUS TREATMENT OF SYMPTOMS AND PATHOLOGY OF PARKINSON'S DISEASE
The invention provides a series of substituted aryl pyrimidine compounds and the use of these compounds as therapeutics to treat or prevent neurodegenerative...
2018/0311242 PYRIMIDINEDIONE COMPOUNDS
Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy...
2018/0311241 PHARMACEUTICAL SYNERGISTIC COMBINATION
The present invention describes a synergistic composition comprising of Fimasartan or pharmaceutically effective salts thereof and a NEP inhibitor or...
2018/0311240 METHODS OF USING DIAMINOPYRIMIDINE P2X3 AND P2X2/3 RECEPTOR MODULATORS FOR TREATMENT OF RESPIRATORY AND...
Methods for treating respiratory and gastrointestinal diseases mediated by a P2X.sub.3 and/or a P2X.sub.2/3 receptor antagonist, the methods comprising...
2018/0311239 HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME
Disclosed are chemical entities which are compounds of formula (I): ##STR00001## or pharmaceutically acceptable salts thereof; wherein Y, R.sup.a, R.sup.a',...
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