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Patent # Description
2018/0311238 Selective Agonist Of a6 Containing nAChRs
The present invention relates to a subtype selective partial agonist of .alpha.6 containing nicotinic acetylcholine receptors. Due to its uniquely selective...
2018/0311237 COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS
Pharmaceutical compositions comprising 5-[2-pyrazinyl]-4-methyl-1,2-3-thione or an analogue, derivative, metabolite, prodrug, solvate or a pharmaceutically...
2018/0311236 USE OF MASITINIB AND OTHER MAST CELL INHIBITORS FOR TREATMENT OF PARKINSON'S DISEASE
Disclosed is a mast cell inhibitor, a pharmaceutical composition and a method for the treatment of patients afflicted with Parkinson's disease, wherein the...
2018/0311235 METHODS OF TREATING DEPRESSION
The present disclosure relates to methods of transitioning patients or obese patients being treated with vortioxetine to treatment with a monoamine oxidase...
2018/0311234 DEVICE AND KIT FOR DOSING AND DISPENSING NON-LIQUID MEDICINE
A device for dosing and dispensing a dose of a non-liquid medicine that comprises a body connectable to a container containing an amount of a non-liquid...
2018/0311233 PHARMACEUTICAL COMBINATION OF OPIOID AND PROSTAGLANDIN COMPOUND
Provided is a method for treating a condition or disease which is one of the indications for opioid use, which comprises administering a combination of: (a) a...
2018/0311232 TRIPLE COMBINATION
The invention provides a combination comprising 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]quinoli- ne or a pharmaceutically acceptable...
2018/0311231 DESETHYLHYDROXYCHLOROQUINE FOR THE TREATMENT OF DISEASES ASSOCIATED WITH INFLAMMATION
Compositions and methods are provided for inhibiting or treating the early and established stages of inflammatory diseases by administration of an effective...
2018/0311230 USE OF LAQUINIMOD TO DELAY HUNTINGTON'S DISEASE PROGRESSION
The subject invention provides methods of treating or delaying disease progression in a subject afflicted with Huntington's disease (HD) comprising...
2018/0311229 C-Met Modulator Pharmaceutical Compositions
Pharmaceutical compositions and unit dosage forms comprising Compound (I) are disclosed. ##STR00001##
2018/0311228 MEDICAL PRODUCT AND METHOD FOR ELIMINATING SYMPTOMS OF NICOTINE WITHDRAWAL
In essence, the present invention relates to a medical product containing a normal saline solution and about 1/8.sup.th of 1 milligram and 3 milligrams of...
2018/0311227 PHARMACEUTICAL COMPOSITION AND USES THEREOF
Pharmaceutical compositions containing a combination of anti-chondrogenesis agents are disclosed. Methods of reducing scleral chondrogenesis, reducing one or...
2018/0311226 METHODS OF TREATMENT USING A JAK INHIBITOR COMPOUND
The invention relates to methods of treating ocular diseases and certain respiratory diseases using the compound ...
2018/0311225 EXTERNAL PREPARATION
The present invention provides an external preparation that exerts excellent allergy treatment effects and comprises a combination of at least one ingredient...
2018/0311224 METHODS OF TREATING OVARIAN CANCER
The present invention provides methods of administering a PARP inhibitor to a cancer patient.
2018/0311223 CRYSTALLINE FORMS OF A JAK INHIBITOR COMPOUND
The present invention provides crystalline hydrates of the oxalate and succinate salts of ...
2018/0311222 Opioid Receptor Ligands And Methods Of Using And Making Same
This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain...
2018/0311221 METHODS OF ADMINISTERING PIRFENIDONE THERAPY
The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors...
2018/0311220 TREATMENT OF CANCERS WITH ACQUIRED RESISTANCE TO KIT INHIBITORS
The present invention provides compositions and methods for treating cancers which have acquired resistance to a KIT inhibitor by administering effective...
2018/0311219 COMPOSITIONS FOR AN ORALLY ACTIVE 1,2,4-OXADIAZOLE FOR THE TREATMENT OF DISEASE
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases...
2018/0311218 Substituted Pyrazole and Pyrrole Compounds and Methods for Using Them for Inhibition of Initiation of...
Disclosed are pyrazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure (I) and...
2018/0311217 METHODS OF TREATMENT AND COMPOSITIONS WITH XANTHINE OXIDASE INHIBITORS
Methods and pharmaceutical compositions for reducing number of gout flares experienced by a patient are disclosed. The methods can comprise administering to a...
2018/0311216 Pharmaceutical Composition Comprising Deferasirox
The present invention relates to a pharmaceutical composition comprising deferasirox, a process for preparing such pharmaceutical composition, and its use in...
2018/0311215 PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR
The invention provides a pharmaceutical composition for injection comprising a NL-101 type compound and a preparation method thereof. The composition uses the...
2018/0311214 ANTIMICROBIAL DRUG SYNTHESIS AND THERAPEUTIC COMPOSITIONS
This invention relates to the medical use of an antimicrobial agent, racemic Ornidazole, its (R) and (S) enantiomers, or pharmaceutically acceptable salts or...
2018/0311213 POLYMORPHIC FORMS OF ST-246 AND METHODS OF PREPARATION
Polymorph forms of 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocy- cloprop[f]isoindol-2(1H)-yl)-benzamide are disclosed as well as...
2018/0311212 BIFUNCTIONAL PRODRUGS
A first aspect of the invention relates to novel compounds and more precisely to novel bifunctional prodrugs and drugs. An additional aspect of the invention...
2018/0311211 ORAL FORMULATIONS OF PYRROLIDINE DERIVATIVES
The present invention relates to solid oral formulations comprising a compound of formula ...
2018/0311210 METHOD FOR INHIBITING GROWTH OF CANCER CELLS
A method of inhibiting the growth of cancer cells is disclosed in which cancer cells that contain an enhanced amount relative to non-cancerous cells of one or...
2018/0311209 DOSING REGIMENS OF PKC ACTIVATORS
Dosing regimens and methods are disclosed for upregulating on protein kinase C (PKC) while reducing subsequent downregulation, comprising administering a PKC...
2018/0311208 USES OF BUTYLIDENEPHTHALIDE
A method for decreasing the incidence rate and/or recurrent rate of cancer is provided. The method comprises administering to a subject in need an effective...
2018/0311207 Novel Methods of Treating Hearing Loss
Provided are methods of treating various forms of hearing loss caused by aberrant calcium fluxes in auditory cells. The methods encompass the administration of...
2018/0311206 USE OF STING AGONISTS TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION
Provided herein are methods of treating a subject having hepatitis B viral (HBV) infection. More specifically, disclosed herein are methods of stimulating the...
2018/0311205 USE OF CANNABINOIDS AND TERPENES FOR TREATMENT OF ORGANOPHOSPHATE AND CARBAMATE TOXICITY
Pharmaceutical compositions in which isolated cannabinoid receptor modulators are optionally combined with terpene blends in a pharmaceutically acceptable...
2018/0311204 METHOD FOR PREVENTING OR TREATING HEART FAILURE
The present invention discloses a method for preventing or treating heart failure, relating to a novel use of nobiletin, the nobiletin reverses cardiac...
2018/0311203 LIQUID FORMULATION OF CABAZITAXEL
The present invention relates to a stable liquid formulation of cabazitaxel. The formulation comprises cabazitaxel, and at least one solubilizer. Typically,...
2018/0311202 METHOD FOR TREATING INFECTIOUS DISEASES WITH ISOTHIOCYANATE FUNCTIONAL COMPOUNDS
A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious...
2018/0311201 ORAL PHARMACEUTICAL COMPOSITION COMPRISING OTILONIUM BROMIDE AND SIMETHICONE WITH CERTAIN BULK DENSITY AND...
The present invention relates to a pharmaceutical composition for oral use comprising therapeutically effective amount of otilonium bromide in combination with...
2018/0311200 OIL COMPRISING POLYUNSATURATED FATTY ACIDS
The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted...
2018/0311198 COMPOSITIONS OF CHLOROGENIC ACID AND METHODS FOR MAKING AND USING THE SAME IN OBESITY MANAGEMENT
The present invention is directed compositions derived from green coffee bean extract and methods for the use and manufacture of such compositions. The...
2018/0311197 METHOD FOR IMPROVING RECOGNITION AND/OR WORKING MEMORY IN HYPERPHENYLALANIMENIA AND PHENYLKETONURIA PATIENTS
The invention pertains to the use of a composition in the manufacture of a product or method for therapeutically improving, promoting, restoring or maintaining...
2018/0311196 METHOD FOR IMPROVING WHITE MATTER INTEGRITY IN HYPERPHENYLALANINEMIA AND PHENYLKETONURIA PATIENTS
The invention pertains to the use of a composition in the manufacture of a productor method for therapeutically improving, promoting, restoring or maintaining...
2018/0311195 Compositions for Diagnosis and Treatment of Type 2 Diabetes
Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided,...
2018/0311194 APPLICATION OF TRANILAST IN PREPARATION OF DRUG TREATING SCLEREDEMA DIABETICORUM
Provided is an application of tranilast in the preparation of a medicament for treating scleredema diabeticorum. Tranilast was originally used clinically for...
2018/0311193 METHOD OF TREATING DELAYED HEALING OF A WOUND ASSOCIATED WITH DIABETES
The method of treating delayed healing of a wound associated with diabetes includes administering to the wound a composition comprising an anti-senescence...
2018/0311192 Compositions and Methods for the Treatment of Cancer
The present invention discloses anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor...
2018/0311191 NEW COMBINATION THERAPIES FOR TREATING NEUROLOGICAL DAMAGE
The invention is directed to combinations of acamprosate and ribavirin, to pharmaceutical compositions, kits and treatment methods for the treatment or...
2018/0311190 BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR TREATING CANCER
Provided are benzenesulfonamide derivatives or pharmaceutically acceptable salts thereof. Also provided is a method for treating cancer by using a...
2018/0311189 Capsaicinoids for Use in Treating ACRAL Lick Granuloma
The invention provides methods for treating acral lick granuloma in a canine using a capsaicinoid, such as capsaicin. The invention also provides methods for...
2018/0311188 ANTI-FUNGAL COMPOSITIONS FOR TREATING NAILS AND METHODS FOR FABRICATING AND USING THEREOF
Pharmaceutical compositions for treating, mitigating or preventing fungal nail diseases, disorders or pathologies are described, the compositions comprising at...
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