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Patent # Description
2018/0326026 METHOD AND COMPOSITION FOR TREATING SARCOPENIA
A method of treating sarcopenia comprises immunizing a subject in need thereof against AGE-modified proteins or peptides of a cell. Immunizing a subject...
2018/0326025 HUMAN-ENZYME MEDIATED DEPLETION OF HOMOCYSTEINE FOR TREATING PATIENTS WITH HYPERHOMOCYSTEINEMIA AND HOMOCYSTINURIA
Methods and compositions relating to the engineering of an improved protein with homocyst(e)inase enzyme activity are described. For example, there are...
2018/0326024 MATERIALS AND METHODS FOR TREATING EMBOLISM
This document relates to materials and methods for treating and/or preventing an embolism (e.g., a cerebral embolism). For example, methods for using a...
2018/0326023 PLASMINOGEN DOSAGE REGIMEN FOR WOUND HEALING
The invention concerns the use of plasminogen or a biologically active variant thereof for the preparation of a medicament for local administration of at least...
2018/0326022 COMPOSITIONS AND METHODS FOR IMPROVING HEART FUNCTION AND TREATING HEART FAILURE
Described herein is a method for improving or stabilizing cardiac function by inhibiting tubulin carboxypeptidase (TCP). Also described herein is a method for...
2018/0326021 Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders
The present disclosure is directed to methods of treating a cytoplasmic glycogen storage disorder, including glycogen storage disease I, glycogen storage...
2018/0326020 METHODS AND COMPOSITIONS FOR REDUCING THE ENVIRONMENTAL IMPACT OF ANIMAL WASTE
Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an...
2018/0326019 COMPOSITIONS COMPRISING ALKALINE PHOSPHATASE AND/OR NATRIURETIC PEPTIDE AND METHODS OF USE THEREOF
The present invention provides methods, compositions, and kits for the treatment of neurocutaneous syndromes, such as neurofibromatosis type I; disorders...
2018/0326018 ALKALINE PHOSPHATASE FORMULATIONS
The present invention provides, in part, formulations comprising an alkaline phosphatase (AP)-based agent. Particularly, modified-release powder formulations...
2018/0326017 METHODS FOR TREATING CRANIOSYNOSTOSIS IN A PATIENT
The disclosure features methods for treating craniosynostosis in a patient (e.g., a patient having hypophosphatasia (HPP) and exhibiting or likely to have...
2018/0326016 TREATING GLAUCOMA, CARDIOVASCULAR DISEASES, AND RENAL DISEASES
This document provides methods and materials related to treating glaucoma, ocular hypertension, cardiovascular diseases, and renal diseases. For example, this...
2018/0326015 PHARMACOLOGICAL USE OF A MYOKINE ABLE TO PRESERVE THE FUNCTION AND MASS OF THE PANCREATIC CELLS UNDER...
Object of the present invention is the use of a known protein, irisin, for preservation of the functionality and survival of the cells of the pancreatic islets.
2018/0326014 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF DIABETES
Disclosed are pharmaceutical formulations for the treatment of diabetes, comprising a combination of insulin with tetra- or pentapeptides having an...
2018/0326013 PROTEIN COMPLEX BY USE OF A SPECIFIC SITE OF AN IMMUNOGLOBULIN FRAGMENT FOR LINKAGE
Provided is a complex composition, of which positional isomers are minimized by using a N-terminus of an immunoglobulin Fc region as a binding site when the...
2018/0326012 METHOD FOR TREATING TUMOR BY USING RECOMBINANT INTERFERON WITH CHANGED SPATIAL CONFIGURATION
The present invention provides methods for treating tumors in subjects by using a recombinant interferon (rSIFN-co), and optionally, methods for treating solid...
2018/0326011 Immunoconjugates
The present invention generally relates to immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-2 polypeptide and a bispecific...
2018/0326010 Immunoconjugates
The present invention generally relates to immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-2 polypeptide and an antibody that...
2018/0326008 COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as...
2018/0326007 COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as...
2018/0326006 COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as...
2018/0326005 COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as...
2018/0326004 COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as...
2018/0326003 EBV ANTIGEN SPECIFIC T-CELL RECEPTOR AND USE THEREOF
The present invention relates to an EBV antigen specific T-cell receptor and the use thereof. Specifically, the present invention provides T cells specific for...
2018/0326002 PEPTIDES DERIVED FROM KITA-KYUSHU LUNG CANCER ANTIGEN (KKLC1, CT83, CXORF61) AND COMPLEXES COMPRISING SUCH...
The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen (CT83), complexes comprising such peptides bound to recombinant...
2018/0326001 Neuroprotective Peptides
The invention relates to the use of an isolated peptide of 10 to 32 amino acid residues in length for the treatment of neural injury, wherein the isolated...
2018/0326000 METHODS AND COMPOSITIONS FOR MODULATING PD1
Disclosed herein are methods and compositions for modulating expression of a PD1 gene.
2018/0325999 POLYPEPTIDE-POLYMER CONJUGATES AND METHODS OF USE THEREOF
The present invention provides polypeptide-polymer conjugates. A subject polypeptide-polymer conjugate is useful in a variety of applications, which are also...
2018/0325998 DELIVERABLE EXTRACELLULAR VESICLES INCORPORATING CELL MEMBRANE TRANSPORT PROTEINS
Disclosed are extracellular vesicles (EVs), such as exosomes, comprising a heterologous cell membrane transporter protein, such as the sodium iodide symporter...
2018/0325997 COMPOUNDS FOR USE IN THE TREATMENT OF TELOMERE RELATED DISEASES AND/OR TELOMERE RELATED MEDICAL CONDITIONS
The invention relates to compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions, particularly wherein said...
2018/0325996 PREVENTION AND TREATMENT OF OCULAR SIDE EFFECTS WITH A CYCLOSPORIN
Therapeutic methods are disclosed herein.
2018/0325995 PROTOCOL FOR TREATMENT OF LUPUS NEPHRITIS
By employing a pharmacodynamic dosing regimen, the effectiveness of a protocol for treatment of lupus nephritis with voclosporin can be maximized while...
2018/0325994 ANTI-BACTERIAL COMPOSITIONS FOR DRUG ADMINISTRATION
Non-toxic aqueous compositions are provided having antibacterial activity. Specifically, the invention provides aqueous alkyl glycoside or saccharide alkyl...
2018/0325993 OCTREOTIDE INJECTION
The present invention relates to a sterile solution comprising: octreotide in the form of a pharmaceutically acceptable salt, present at a concentration...
2018/0325992 MODULATION OF AXON DEGENERATION
The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using...
2018/0325991 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325990 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325989 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325988 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325987 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325986 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325985 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325984 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325983 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325982 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2018/0325981 AGONIST PEPTIDE FOR ADIPONECTIN RECEPTOR
A peptide includes SEQ ID NO: 1 (Xaa1-Tyr-Phe-Ala-Tyr-His-Pro-Asn-Ile-Pro-Gly-Leu-Xaa2-Tyr-Phe), wherein Xaa1 is any one selected from the group consisting of...
2018/0325980 COMPOSITION FOR IMPROVING MEMORY, LEARNING ABILITY, AND COGNITIVE ABILITY
There is provided a composition for improving memory, learning ability, and cognitive ability. It has been confirmed that a peptide having a C-terminal region...
2018/0325979 PEPTIDE-INDUCED NK CELL ACTIVATION
The invention relates to a peptide capable of activating NK cell-mediated immunity, the peptide comprising or consisting of the amino acid sequence XnAX2X1,...
2018/0325978 USE OF COMPLEXES OF WHEY PROTEIN MICELLES AND PECTIN FOR MANAGING BODY WEIGHT
The present invention relates to a composition comprising complexes of whey protein micelles and pectin for use in the treatment or prevention of obesity or...
2018/0325977 COLLAGEN PEPTIDE-BASED MEDICAMENT COMPOSITIONS AND DEVICES AND METHODS OF PRODUCTION AND USE THEREOF
The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more...
2018/0325976 ANGIOGENESIS INHIBITOR
An angiogenesis inhibitor effective in inhibiting angiogenesis which causes a disease is obtained by, for example, sterilely filtrating, disinfecting, and...
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