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Patent # Description
2018/0327795 METHOD FOR PREPARING ANTHOCYANIN OLIGOMERS BY USING COENZYME DERIVED FROM ASPERGILLUS SP. STRAIN
The present invention relates to a method of preparing an anthocyanin oligomer using a coenzyme derived from an Aspergillus sp. strain, and more particularly...
2018/0327794 Enzymatic Epoxydation Of Natural Rubber
Disclosed is a method for epoxidating natural rubber using enzymes that generate reactive oxygen species.
2018/0327793 METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS
The present disclosure provides methods for preparing .beta.-substituted tryptophan compounds. The methods include: combining i) an unsubstituted indole or a...
2018/0327792 Fermented Hydrolyzed Plant-Origin Material
A method and composition can provide fermented plant-origin material. The method can comprise several steps. A first step comprises hydrolyzing a plant-origin...
2018/0327791 Method for Producing C4-Dicarboxylic Acid
Provided is a transformed cell improved in C4 dicarboxylic acid productivity. A transformed cell containing a foreign polynucleotide encoding a polypeptide...
2018/0327790 A SYSTEM FOR IMPROVED PRODUCTION TITERS IN FERMENTATIONS
The invention provides a genetically modified micro-organism for intracellular biosynthesis of a cellular metabolite, comprising a synthetic error correction...
2018/0327789 METHODS FOR PRODUCTION OF OXYGENATED TERPENES
The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides,...
2018/0327788 MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL,...
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents...
2018/0327787 NOVEL SUCROSE UNASSIMILATING FLOCCULENT YEAST
An object of the present invention is to provide a sucrose unassimilating yeast which has a flocculation ability and has much of a proven performance of food...
2018/0327786 NOVEL CRISPR ENZYMES AND SYSTEMS
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or...
2018/0327785 CAS PROTEINS AND GUIDE RNA SYSTEMS FOR GENOME EDITING
Compositions and methods are provided for restoring function to a non-functional gene product in the genome of a cell. The methods and compositions employ a...
2018/0327784 Nuclease-Independent Targeted Gene Editing Platform and Uses Thereof
The present invention discloses a system for targeted gene editing and related uses.
2018/0327783 TRANSDUCTION BUFFER
The invention relates to transduction compounds, buffers and methods for introducing molecules into cells. The invention also relates to methods of treatment,...
2018/0327782 LENTIVIRAL VECTORS AND USES THEREOF
The invention relates to compositions containing polynucleotide vectors capable of expressing a nucleic acid encoding a fusion polypeptide on the surface of a...
2018/0327781 NOVEL RNA-BASED VECTOR SYSTEM FOR TRANSIENT AND STABLE GENE EXPRESSION
The present application generally compositions comprising a synthetic delivery RNA comprising a first sequence from a viral genome and/or a second sequence...
2018/0327780 CYP-P22 BIOCATALYTIC NANOPARTICLES WITH CYTOCHROME P450 ACTIVITY FOR PRODRUG ACTIVATION
Hybrid proteins with cytochrome P450 activity and which are encapsulated in a nanocapsid (nanoparticles charged with cytochrome P450 activity) are designed and...
2018/0327779 MULTIPLE VECTOR SYSTEM AND USES THEREOF
The present invention relates to constructs, vectors, relative host cells and pharmaceutical compositions which allow an effective gene therapy, in particular...
2018/0327778 ANIMAL MODELS FOR BRAIN INFLAMMATION AND WHITE MATTER DEGENERATION
Provided are methods of making and using animal models for brain inflammation and white matter degeneration.
2018/0327777 ENHANCED EXPRESSION AND STABILITY REGIONS
Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant...
2018/0327776 AXMI554 DELTA-ENDOTOXIN GENE AND METHODS FOR ITS USE
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding...
2018/0327775 Rust Resistance Gene
The present invention relates to new transporter polypeptides, and genes encoding therefor, which can be used to confer upon a plant resistance to one or more...
2018/0327774 EPSPS MUTANTS
The present invention relates to the production of a non-transgenic plant resistant or tolerant to a herbicide of the phosphonomethylglycine family, e.g.,...
2018/0327773 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES
Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure...
2018/0327772 METHODS OF ENGINEERED TISSUE SUCCULENCE IN PLANTS
Disclosed herein are methods of altering tissue succulence in plants. In some examples, a disclosed method includes overexpressing a modified helix-loop-helix...
2018/0327771 YIELD AND STRESS TOLERANCE IN TRANSGENIC PLANTS IV
Polynucleotides and polypeptides incorporated into expression vectors have been introduced into plants and were ectopically expressed. The polypeptides of the...
2018/0327770 GUAYULE WITH INCREASED RUBBER PRODUCTION AND YIELD
A reduction in the amount of functional PaAos in guayule results in the production of increased amounts rubber compared to the amount of rubber produced by...
2018/0327769 PAPAVER SOMNIFERUM STRAIN WITH HIGH CONCENTRATION OF THEBAINE
The present invention is directed to an improved poppy straw, concentrate of poppy straw and opium of Papaver somniferum for the production of thebaine...
2018/0327768 TARGETED DELIVERY OF THERAPEUTIC PROTEINS BIOENCAPSULATED IN PLANT CELLS TO CELL TYPES OF INTEREST FOR THE...
Compositions and methods for producing therapeutic fusion proteins comprising targeting sequences directing the protein to cells or tissues of interest are...
2018/0327767 COMPOSITIONS AND METHODS FOR PRODUCING STARCH WITH NOVEL FUNCTIONALITY
This invention disclosure relates to novel maize starch. The starch can be made from the newly developed waxy sugary-2 double-mutant maize that has low...
2018/0327766 NUCLEIC ACID SEQUENCES ENCODING TRANSCRIPTION FACTORS REGULATING ALKALOID BIOSYNTHESIS AND THEIR USE IN...
Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment,...
2018/0327765 GUAYULE WITH INCREASED RUBBER PRODUCTION AND YIELD
Altered guayule that produce more rubber than the amount of rubber produced by non-altered guayule are provided. The alterations may include (i) a reduction in...
2018/0327764 PRODUCTION OF IN VIVO N-DEGLYCOSYLATED RECOMBINANT PROTEINS BY CO-EXPRESSION WITH ENDO H
Plants have emerged as an alternative expression system and are increasingly being used by industry and academia for producing target proteins. However, the...
2018/0327763 SORGHUM-DERIVED TRANSCRIPTION REGULATORY ELEMENTS PREDOMINANTLY ACTIVE IN ROOT HAIR CELLS AND USES THEREOF
Transcription regulatory elements, namely promoter and terminator sequences, obtained from Sorghum bicolor that drive RNA transcription predominately in root...
2018/0327762 BIOCONTAINMENT/BIOCONTROL SYSTEM AND METHODS
This disclosure describes, in one aspect, a cell that includes a biocontainment system. Generally, the biocontainment system includes a coding region whose...
2018/0327761 METHOD FOR PRODUCING PRECISE DNA CLEAVAGE USING CAS9 NICKASE ACTIVITY
The present invention is in the field of a method for genome engineering based on the type II CRISPR system, particularly a method for improving specificity...
2018/0327760 PLANTS AND SEEDS OF CORN VARIETY CV375294
According to the invention, there is provided seed and plants of the corn variety designated CV375294. The invention thus relates to the plants, seeds and...
2018/0327759 Transgenic plants with enhanced agronomic traits
This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to...
2018/0327758 RECOMBINANT MICROALGAE INCLUDING KETO-ACYL ACP SYNTHASE
Methods and compositions for the production of food compositions, oils, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided,...
2018/0327757 ENHANCED PROTEIN EXPRESSION AND METHODS THEREOF
The present disclosure is generally related to modified Gram positive bacterial cells producing increased amounts of one or more protein(s) of interest and...
2018/0327756 CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and...
2018/0327755 TREATMENT OF AGE-RELATED MACULAR DEGENERATION USING RNA COMPLEXES THAT TARGET MYD88 OR TLR3
In certain aspects, provided herein are RNA complexes that inhibit Myeloid differentiation primary response gene 88 (MyD88) and/or Toll-like receptor 3 (TLR3)...
2018/0327754 Modulation of CCR10 Signals for Treatment of Skin and Intestinal Inflammatory Diseases and Infection
The invention provides compositions and methods for targeting CCR10 and/or the CCR10/ligand axis to modulate the immune response in a subject.
2018/0327753 MEANS AND METHODS FOR REDUCING TUMORIGENICITY OF CANCER STEM CELLS
Provided are RNA inhibitory molecules, particularly siRNA molecules silencing the expression of Voltage-Dependent Ion Chanel-1 (VDAC1) for the induction of...
2018/0327752 METHODS AND COMPOSITIONS FOR MODULATING AAV INFECTION
Compositions and methods are provided for modulating adeno-associated virus (AAV) infection. For example, compositions and methods are provided for enhancing...
2018/0327751 siRNA COMPOSITIONS THAT SPECIFICALLY DOWNREGULATE EXPRESSION OF A VARIANT OF THE PNPLA3 GENE AND METHODS OF USE...
The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a...
2018/0327750 Methods and Compositions for Reducing Immunosupression by Tumor Cells
The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells...
2018/0327749 ANTISENSE COMPOSITION AND METHOD FOR TREATING MUSCLE ATROPHY
A method and compound for treating skeletal muscle mass deficiency in a human subject are disclosed. The composition is an oligomer of morpholino subunits and...
2018/0327748 RNA INTERFERENCE IN SKIN INDICATIONS
The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal...
2018/0327747 EXOGENOUS CONTROL OF MAMMALIAN GENE EXPRESSION THROUGH APTAMER-MEDIATED MODULATION OF POLYADENYLATION
Embodiments of the disclosure concern the use of expression constructs in which at least one polyA signal is embedded upstream of an expressible transcript,...
2018/0327746 Alpha-AMYLASE-BINDING NUCLEIC ACID MOLECULE AND USE THEREOF
The present invention provides a novel nucleic acid molecule that can be used for detection of .alpha.-amylase. The .alpha.-amylase-binding nucleic acid...
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