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Patent # Description
2018/0371433 THERMOSTABLE HALOARCHAEAL INORGANIC PYROPHOSPHATASE
The invention pertains to a PPA from a microorganism belonging to the family Halobacteriaceae (HPPA), for example, a PPA from Haloferax volcanii. The HPPA...
2018/0371432 TE2FT ENZYME FOR ENZYMATIC SYNTHESIS OF ALPHA1-2-FUCOSIDES
.alpha.1-2-fucosyltransferases, and methods and compositions for making and using .alpha.1-2-fucosyltransferases, are described herein.
2018/0371431 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF ARMODAFINIL
The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods...
2018/0371430 Heme Protein Catalysts for Carbon-Silicon Bond Formation In Vitro and In Vivo
The present invention provides compositions and methods for catalyzing the formation of carbon-silicon bonds using heme proteins. In certain aspects, the...
2018/0371429 AMADORIASE HAVING IMPROVED SPECIFIC ACTIVITY
This invention provides an amadoriase having improved specific activity on a glycated substrate, compared with conventional amadoriase. Provided is an...
2018/0371428 KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase...
2018/0371427 BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES
The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides,...
2018/0371426 CHROMATOGRAPHY BASED PURIFICATION STRATEGIES FOR VIRUSES
The present invention provides purification strategies for sterically demanding, i.e. large and pleomorphic, infectious virus particles or VLPs derived...
2018/0371425 ONCOLYTIC ADENOVIRUSES WITH INCREASED PROPORTION OF THE 156R SPLICING ISOFORM OF THE E1B PROTEIN
The invention relates to a recombinant adenovirus that has an oncolytic effect in a cancer cell. By modulating the level and type of splice isoforms of the E1B...
2018/0371424 PRRSV SX-105 strain and use thereof
The present invention relates to porcine reproductive and respiratory syndrome virus (PRRSV) vaccines in a field of veterinary biological products, and more...
2018/0371423 NON-VIRAL IPSCS INDUCING METHOD, COMPOSITIONS, KITS AND IPSCS
The present invention relates to a non-viral iPSCs induction method as well as the compositions, kits and iPSCs obtained therefrom. More specifically, the...
2018/0371422 NON-VIRAL IPSCS INDUCING METHOD, COMPOSITIONS, KITS AND IPSCS
The present invention relates to a non-viral iPSCs induction method as well as the compositions, kits and iPSCs obtained therefrom. More specifically, the...
2018/0371421 METHODS AND COMPOSITIONS RELATED TO DIFFERENTIATED LUNG CELLS
Described herein are methods and compositions related to induced alveolar epithelial type 2 cells (iAEC2s), e.g., artificially-produced epithelial type 2 cells.
2018/0371420 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO PANCREATIC ENDOCRINE CELLS
The present invention provides methods to promote differentiation of pancreatic endoderm cells to pancreatic endocrine rich clusters and to enhance insulin...
2018/0371419 METHOD OF FABRICATING SUBSTRATE FOR CULTURING STEM CELL
The present disclosure relates to a method of fabricating a substrate for culturing stem cells, including forming a plasma polymer layer from a precursor...
2018/0371418 FORMULATION COMPRISING EXTRACELLULAR VESICLES, METHOD FOR PRODUCING THE SAME, AND USES THEREOF
Disclosed herein is a formulation comprising an extracellular vesicle (EV), and a therapeutic active agent induced or embedded in the EV. According to...
2018/0371417 BOVINE SERUM COMPOSITION AND METHOD FOR CULTURING CELLS USING SAID BOVINE SERUM COMPOSITION AS ADDITIVE
Provided is a method for producing an economical bovine serum composition containing many factors useful for cell proliferation. The method includes a step of...
2018/0371416 SCAFFOLD-FREE TISSUE CONSTRUCTS
A tissue construct comprising includes a self-assembled, scaffold-free, high-density cell aggregate. The cell aggregate includes a plurality of cells and a...
2018/0371415 TISSUE-ENGINEERED THREE-DIMENSIONAL MODEL FOR TUMOR ANALYSIS
A 3D decellularized bone scaffold seeded with cancer cells, such as prostate cancer cells or Ewing's sarcoma is provided. The three-dimensional includes...
2018/0371414 ICOS Critically Regulates the Expansion and Function of Inflammatory Human Th17 Cells
The invention includes compositions and methods for generating and expanding therapeutic Th17 cells. The invention includes contacting T cells with a...
2018/0371413 PRODUCTS AND METHODS FOR ACTIVATING AND/OR EXPANDING T CELLS
The present disclosure relates to products and methods for activating and/or expanding T cells. Certain embodiments of the present disclosure provide a porous...
2018/0371412 THERAPEUTIC T CELLS
Use of C-X-C chemokine receptor type 4 (CXCR4) for increasing the capacity for self-renewal and/or persistence in a T cell; increasing the capacity for...
2018/0371411 KIDNEY-SPECIFIC TUMOR VACCINE DIRECTED AGAINST KIDNEY TUMOR ANTIGEN G-250
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers...
2018/0371410 MEANS AND METHODS FOR INFLUENCING THE STABILITY OF CELLS
The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6...
2018/0371409 METHOD FOR PRODUCING CILIARY MARGINAL ZONE-LIKE STRUCTURE
The invention provides a method for producing a cell aggregate containing a ciliary marginal zone-like structure by culturing a cell aggregate containing a...
2018/0371408 CELL CULTURES AND METHODS OF USE
Provided herein is a composition that includes spermatogonial cells, Sertoli cells, and Leydig cells, and an optional protein matrix. In one embodiment, the...
2018/0371407 METHODS OF GENERATING TISSUE USING DEVITALIZED, ACELLULAR SCAFFOLD MATRICES DERIVED FROM MICRO-ORGANS
A composition of matter is provided comprising a devitalized, acellular tissue-derived scaffold seeded with differentiated cells, particularly pancreatic islet...
2018/0371406 Unitary 3D Culture Device
A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing...
2018/0371405 METHODS AND COMPOSITIONS FOR DELIVERY OF CRISPR BASED ANTIMICROBIALS
The invention is directed to antibacterial compositions comprising bacteria modified to comprise phasmids engineered to deliver of CRISPR RNAs and methods for...
2018/0371404 METABOLIC ENGINEERING OF MEMBRANE PROTEINS TO IMPROVE ESCHERICHIA COLI MEMBRANE INTEGRITY AND PRODUCTION OF...
The present disclosure provides bacteria with improved membrane integrity related primarily to outer membrane protein content and increased fatty acid...
2018/0371403 Facultative Endophytic Plant Growth Promoting Bacteria
Described herein are two bacterial strains, designated as KGS-2 and KGS-8 which have been shown to solubilize soil phosphorus and to enhance the growth of...
2018/0371402 Medium composition for producing alpha-glucosidase inhibitors fermented from Paenibacillus
A medium composition for producing alpha-glucosidase inhibitors fermented from Paenibacillus, comprising chitin as a carbon source, proteome as a nitrogen...
2018/0371401 GREEN ALGAE MUTANT EXHIBITING RESISTANCE TO INTENSE LIGHT, AND USE THEREOF
While green algae are expected to serve as raw materials of biomass fuels, they are damaged by high-intensity light when subjected to mass-culture outdoors in...
2018/0371400 ELECTROMECHANICAL LYSIS OF BACTERIAL PATHOGENS USING ION CONCENTRATION POLARIZATION
Scalable, high throughput and power-efficient electromechanical lysis using low electric potential, which can be used for harvesting valuable intracellular...
2018/0371399 IMPROVEMENTS IN AND RELATING TO INSTRUMENTS FOR PROCESSING CELLS
Disclosed herein is an instrument suitable for processing cells for example culturing, concentrating or washing said cells, the instrument comprising: a...
2018/0371398 CELL CULTURING SYSTEM FOR CULTURING ADHERENT CELLS AND LIQUID SUPPLY INTERFACE COMPRISING A CELL CULTURE CONTAINER
The invention relates to a liquid supply interface for a cell culture system for supplying cell cultures found in different cell culture containers with a...
2018/0371397 CELL CULTURING SYSTEM FOR CULTIVATING ADHERENT CELLS AND LIQUID SUPPLY INTERFACE COMPRISING A CELL CULTURE...
The invention relates to a liquid supply interface for a cell culture system for supplying cell cultures found in different cell culture containers with a...
2018/0371396 CELL CULTURE SYSTEM, CELL CULTURE ENVIRONMENT EVALUATION DEVICE, AND PROGRAM
An object of the present disclosure is to provide a cell culture system, a cell culture environment evaluation device, and a program, capable of performing...
2018/0371394 Automatic Multi-tray and Multi-plate Bioreactor Systems for Adherent Cultures
Disclosed herein is an improved automatic bioreactor system utilizing a multi-tray or multi-plate cell culture vessel for cultivating adherent cells.
2018/0371393 IMPROVEMENTS IN AND RELATING TO CELL HARVESTING APPARATUS
Disclosed herein is a cell harvesting instrument suitable for concentrating cells from a source suspension of cells and/or washing said cells, the instrument...
2018/0371392 INLAY FOR A CULTURE PLATE AND CORRESPONDING METHOD FOR PREPARING A CULTURE PLATE SYSTEM WITH SUCH INLAY
The present invention is concerned with an inlay (10) for a culture plate (20) for microorganisms or cells, a culture plate unit (30) for microorganisms or...
2018/0371391 PURE ALGAE GROWTH SYSTEM AND METHOD
A tank receives, mixes, and dispenses input materials including algae feed stock, a micro-nutrients, cleaning solution, a sterile gas, a heating/cooling fluid,...
2018/0371390 A CELL CULTURE DEVICE
A cell culture device comprising a container, at least one divider and a plurality of cell growth blocks located within the container. The divider separates...
2018/0371389 Method and Apparatus for Generating Three-Dimensional Patterned Soft Structures and Uses Thereof
A method for generating a three-dimensional patterned soft structure, including the steps of providing a soft supporting substrate, providing a drop-on-demand...
2018/0371388 CELL CULTURE DEVICE
Cell culture device includes incubator unit that cultures cells in culture container, transport unit that transports culture container to incubator unit, task...
2018/0371387 FLAVOR INFUSED ALCOHOLIC BEVERAGE AND METHOD OF MAKING THE SAME
The present invention is an alcoholic beverage having the sensory characteristics of a flavored distilled spirit. The method for making the alcoholic beverage...
2018/0371386 HIGH PRESSURE PROCESSING (HPP) FOR INFUSING FLAVOR INTO LIQUIDS CONTAINING ALCOHOL
A method for infusing a flavor from a substance into an infusion liquid. The method includes placing the infusion liquid and the substance into a vessel, where...
2018/0371385 BEVERAGE MAKER
A beverage maker includes a fermentation tank having an inner space, a water tank that supplies water to the fermentation tank, and an ingredient supply...
2018/0371384 METHOD FOR PRODUCING ROOTING-SUPPRESSED MALT
A method for producing malts, including steeping barley in steeping water containing phosphoric acid, and a method for producing foodstuff (for example, a...
2018/0371383 COATED DETERGENT TABLET
The invention relates to a detergent tablet comprising a body made from compacted powder, said body being coated with a water-soluble coating, said...
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