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Patent # Description
2018/0371129 ETHYLENE AND BUTADIENE COPOLYMER HAVING A HOMOGENEOUS MICROSTRUCTURE
An ethylene/butadiene copolymer comprising statistically distributed ethylene units and butadiene units is provided. The molar fraction of the ethylene units...
2018/0371128 Functionalized polydicyclopentadiene polymer
Disclosed herein are embodiments of methods for making and using functionalized forms of polydicyclopentadiene polymers. The disclosed polymers and methods...
2018/0371127 METHOD FOR PRODUCING VINYL ETHER POLYMER HAVING HYDROXYL GROUP ON SIDE CHAIN AND TEMPERATURE-RESPONSIVE POLYMER...
[Object] To provide a method for producing a vinyl ether polymer having a hydroxyl group on the side chain, wherein the vinyl ether polymer having a low...
2018/0371126 ARTICLES WITH IMPROVED OPTICAL PROPERTIES
Molded articles comprising a polypropylene homopolymer with rather high melt flow rate, high stiffness, improved optical properties and an advantageous balance...
2018/0371125 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME
The present invention relates to a modified conjugated diene-based polymer, and more particularly, provides a modified conjugated diene-based polymer which...
2018/0371124 PHOTOCURABLE ELECTRON DEFICIENT OLEFIN-CONTAINING COMPOSITIONS
This invention relates to photocurable electron deficient olefin-containing compositions, such as those containing certain 2-cyanoacrylates,...
2018/0371123 LIGHT GENERATING MICROCAPSULES FOR SELF-HEALING POLYMER APPLICATIONS
A self-healing polymeric material includes a polymeric matrix material, a plurality of monomer mixture microcapsules dispersed in the polymeric matrix...
2018/0371122 LIGHT GENERATING MICROCAPSULES FOR SELF-HEALING POLYMER APPLICATIONS
A self-healing polymeric material includes a polymeric matrix material, a plurality of monomer mixture microcapsules dispersed in the polymeric matrix...
2018/0371121 FLUOROPOLYMER DISPERSION
Aqueous fluoropolymer dispersions are described, along with coatings obtained with the dispersions, and methods of making coatings and dispersions.
2018/0371120 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND...
A method for producing a solid catalyst for olefin (co)polymerization includes bringing into contact with each other a magnesium compound, a tetravalent...
2018/0371119 PROCESS FOR PROVIDING INORGANIC POLYMER CERAMIC-LIKE MATERIALS
A process for providing inorganic polymer ceramic-like materials. The process comprises providing a first material which comprises at least one non-oxide...
2018/0371118 Epoxidized Oil and Resin Compositions
In some aspects, the disclosure relates to thermoset polymeric compositions consisting of functional bio-based epoxies and/or their derivatives (e.g....
2018/0371117 SYNTHESIS AND ASSEMBLY OF CLICKABLE MICROGELS INTO CELL-LADEN POROUS SCAFFOLDS
This invention is in the field of medicinal chemistry. The present invention provides cell-laden hydrogels and hydrogel assemblies thereof for use in tissue...
2018/0371116 LIGAND COMPOUND, TRANSITION METAL COMPOUND AND CATALYST COMPOSITION INCLUDING THE TRANSITION METAL COMPOUND
The present invention relates to a novel ligand compound, a transition metal compound and a catalyst composition including the transition metal compound. The...
2018/0371115 PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND CO-POLYMERIZATION
The present invention relates to a process for preparing a solid catalyst component suitable for producing polyethylene and its copolymers, said process...
2018/0371114 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD OF PREPARING THE SAME
The present invention relates to a modified conjugated diene-based polymer, and more particularly, provides a modified conjugated diene-based polymer including...
2018/0371113 MODIFIER, MODIFIED AND CONJUGATED DIENE-BASED POLYMER AND METHODS FOR PREPARING THEM
The present invention relates to a modifier and a modified and conjugated diene-based polymer including a functional group derived therefrom, and more...
2018/0371112 PROCESS FOR EXTRACTING RESIN AND RUBBER FROM GUAYULE PLANTS
The present invention relates to the sector of the industry for extracting and processing natural rubber, and other components, from plant material. In...
2018/0371111 PROCESS FOR EXTRACTING LATEX, RESIN AND RUBBER FROM GUAYULE PLANTS
The present invention relates to the industrial sector of extracting and processing natural rubber, and other components, from plant material. In particular,...
2018/0371110 MODIFIED CYCLODEXTRINS FOR THE SELECTIVE SEQUESTRATION OF FENTANYL RELATED COMPOUNDS AND USES THEREOF
Novel thioalkylcarboxylate-modified CDs and pharmaceutical compositions comprising these thioalkylcarboxylate-modified CDs are disclosed, as well as methods of...
2018/0371109 METHOD FOR PRODUCING CELLULOSE NANOFIBER DRY SOLID
A method for producing a dry solid of cellulose nanofiber, the method comprising (A) preparing a dispersion in which cellulose nanofiber with an average fiber...
2018/0371108 Antibody specific to staphylococcus aureus, therapeutic method and detection method using same
We provide new monoclonal antibody inhibitors of coagulases for treatment of S. aureus. The monoclonal antibodies are useful in targeting the SC N-terminus and...
2018/0371107 NSP4 INHIBITORS AND METHODS OF USE
The invention provides NSP4 inhibitors (such as anti-NSP4 antibodies) and methods of using the same.
2018/0371106 MONOCLONAL ANTIBODIES FOR USE IN DIAGNOSIS AND THERAPY OF CANCERS AND AUTOIMMUNE DISEASE
The specification describes the sequences for antibodies that recognize the HLA-A2-restricted peptide PR-1 in the context of HLA presentation on the surface of...
2018/0371105 IDENTIFICATION AND USE OF NEW TUMOR-PROMOTING GENE IN HEMATOLOGICAL MALIGNANCIES
Methods are provided for diagnosing and treating a blood cancer or a myelodysplastic syndrome in a subject. Associated compositions and kits therefor are also...
2018/0371104 Deimmunized Serum-Binding Domains and Their Use in Extending Serum Half-Life
The present invention is directed to a polypeptide (for example, an antigen-binding molecule) that comprises a polypeptide portion of a deimmunized...
2018/0371103 ANTIBODIES AGAINST IMMUNOGENIC GLYCOPEPTIDES, COMPOSITIONS COMPRISING THE SAME AND USE THEREOF
Disclosed herein are antibodies which specifically bind to at least one epitope defined by the immunogenic glycopeptide. Other aspects of the present...
2018/0371102 NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also...
2018/0371101 INTRAVESICAL THERAPY FOR BLADDER CANCER
This invention relates to an intravesical therapy for bladder cancer.
2018/0371100 ANTIBODY WHICH SPECIFICALLY BINDS TO HUMAN CRTH2
There is provided an anti-human CRTH2 antibody which has desired activity by recognizing and binding to a specific human CRTH2; the antibody fragment; DNA...
2018/0371099 THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER
The present invention provides therapeutic and diagnostic methods and compositions for cancer, for example, bladder cancer. The invention provides methods of...
2018/0371098 ANTI-JAGGED1 ANTIBODIES AND METHODS OF USE
The invention provides anti-Jagged1 antibodies and methods of using the same.
2018/0371097 CANINIZED HUMAN ANTIBODIES TO HUMAN IL-4R ALPHA
The present invention provides caninized human anti-human IL-4R.alpha. antibodies that have specific sequences and a high binding affinity for canine...
2018/0371096 ANTI-AXL ANTIBODIES
Antibodies which specifically bind to the Axl protein are described. Also disclosed are methods for the production and use of the anti-Axl antibodies.
2018/0371095 HYBRIDOMA CLONES, MONOCLONAL ANTIBODIES TO VSIG-4, AND METHODS OF MAKING AND USING
Described herein are monoclonal antibodies that bind to VSIG-4 including antibodies that block the binding of VSIG-4 to SIGLEC-7, compositions including the...
2018/0371094 METHOD FOR PURIFYING ACTIVE POLYPEPTIDES OR IMMUNOCONJUGATES
The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active...
2018/0371093 ANTIBODY MOLECULES TO PD-1 AND USES THEREOF
Antibody molecules that specifically bind to PD-1 are disclosed. The antibody molecules can be used to treat or prevent cancerous or infectious conditions and...
2018/0371092 TREATMENT OF LUNG CANCER USING A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND AN ANTI-CTLA-4 ANTIBODY
This disclosure provides a method for treating a subject afflicted with a lung cancer, which method comprises administering to the subject therapeutically...
2018/0371091 GENE SIGNATURES FOR DETERMINING ICOS EXPRESSION
Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene...
2018/0371090 Antibodies Comprising Chimeric Constant Domains
Antibodies, antigen-binding proteins and Fc-fusion proteins that comprise recombinant polypeptides containing a chimeric heavy chain constant region sequence...
2018/0371089 ASYMMETRIC HETERODIMERIC FC-SCFV FUSION ANTI-GLOBO H AND ANTI-CD3 BISPECIFIC ANTIBODY AND USES THEREOF IN CANER...
A bispecific anti-Globo H antibody includes an anti-Globo H antibody that binds specifically to Globo H; and a T-cell targeting domain fused to a CH3 domain of...
2018/0371088 TARGET CELL-DEPENDENT T CELL ENGAGING AND ACTIVATION ASYMMETRIC HETERODIMERIC Fc-ScFv FUSION ANTIBODY FORMAT...
An asymmetric heterodimeric antibody includes a knob structure formed in a CH3 domain of a first heavy chain; a hole structure formed in a CH3 domain of a...
2018/0371087 OPTIMIZATION OF ANTIBODIES THAT BIND LYMPHOCYTE ACTIVATION GENE-3 (LAG-3), AND USES THEREOF
The present invention provides isolated monoclonal antibodies that specifically bind LAG-3, and have optimized functional properties compared to previously...
2018/0371086 MULTISPECIFIC ANTIBODIES THAT TARGET HIV GP120 AND CD3
Multispecific antibodies (e.g., bispecific antibodies) that bind to HIV gp120 and CD3 are disclosed. Also disclosed are methods of using such antibodies to...
2018/0371085 ANTIBODIES TARGETING FC RECEPTOR-LIKE 5 AND METHODS OF USE
The presently disclosed subject matter provides fully human antibodies or antigen-binding fragments thereof that bind to FcRL5 and methods of using the same.
2018/0371084 HUMAN ANTI-PD-1, PD-L1, AND PD-L2 ANTIBODIES AND USES THEREFOR
The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to...
2018/0371083 ANTI-TIGIT ANTIBODIES
The present invention relates to anti-TIGIT antibodies, as well as use of these antibodies in the treatment of diseases such as cancer and infectious disease.
2018/0371082 NOVEL ANTIBODY USEFUL IN NEUROLOGICAL OR NEURODEGENERATIVE DISORDERS
The present invention relates to an anti-NMDA antibody or fragment or derivative thereof which is effective in inhibiting the deleterious effects of...
2018/0371081 Novel Modulators
Antibodies that modulate insulin receptor signaling are provided.
2018/0371080 BINDING AGENTS AFFECTING GHSR ACTIVITY AND METHODS OF USE THEREOF
The present disclosure provides binding agents that modulate the interaction between LEAP2 and GHSR. Specifically, the present disclosure provides binding...
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